Clinical trials: Intracranial Aneurysms
Cerebral Aneurysm, Arteriovenous Malformations
Exploration of Anticoagulation Program in Cerebral Aneurysm and Arteriovenous Malformations With Hybrid Operation 2
In the stage of randomized controlled study, our purpose is to obtain the Intraoperative anticoagulation program supported by evidence-based medicine.
- Trial name
- EAPCAAMHO2 (NCT03306836)
- Testing
- Heparin Sodium
- Where
- China
- Volunteers
- 408 people
- Sponsor
- Beijing Tiantan Hospital
Brain Aneurysm, Intracranial Hemorrhages
Outcome Study of the Pipeline Embolization Device With Vantage Technology in Unruptured Aneurysms
In this project the investigators study the safety and efficacy of the pipeline embolization device with vantage technology in treatment of unruptured brain aneurysms
- Conditions
- Brain Aneurysm, Intracranial Hemorrhages, Stroke
- Trial name
- PEDVU (NCT05626504)
- Testing
- Pipeline Embolization Device with Vantage Technology
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- King's College Hospital NHS Trust
Intracranial Aneurysm, Arteriovenous Malformations, Cerebral
Patient-specific Planning of Minimally Invasive Brain Interventions Based on Vascular-hemodynamic Mapping
Endovascular procedures for treating brain aneurysms and arteriovenous malformations (AVMs) are becoming increasingly popular due to their less invasive nature and lower risk of complications.
- Trial name
- NCT06588543
- Testing
- Endovascular treatment
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- University Hospital, Ghent
Subarachnoid Hemorrhage, Aneurysmal
New Therapeutic System of Ruptured Intracranial Aneurysms Based on Big Data From Chinese Population
This study aims at clarifying the current situation of Emergency treatment of aneurysmal subarachnoid hemorrhage (SAH) in China, and analyzing the safety and efficacy of the treatment strategy between interventional treatment and…
- Trial name
- NATIONAL-2 (NCT03153748)
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Changhai Hospital
Intracranial Aneurysm
Hemodynamic Analysis for Intracranial Aneurysms Recanalization After Endovascular Treatment
This study was designed to collect a large series of patients with aneurysms treated endovascularly to analyze hemodynamic factors that affect aneurysm recanalization.
- Trial name
- HARET (NCT02812108)
- Testing
- intracranial stent, flow diverter and coils
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Neurosurgical Institute
Intracranial Aneurysm
Cascade Clinical Data Collection Protocol
This study is a multi-center, single arm, open label, retrospective and prospective clinical data collection of CascadeTM, Non-Occlusive Remodeling Net, in adults with intracranial aneurysms, demonstrating the effectiveness and…
- Trial name
- NCT04760925
- Testing
- CascadeTM, Non-Occlusive Remodeling Net
- Where
- 7 sites in Bulgaria, Germany and 3 more
- Volunteers
- 112 people
- Sponsor
- Perflow Medical
Unruptured Cerebral Aneurysm, Artificial Intelligence (AI)
AI Models for Cerebral Aneurysms Segmentation, Detection and Stability Prediction
Aneurysmal subarachnoid hemorrhage (SAH) is one of the critical diseases that severely threaten human health, with a clinical mortality rate reaching as high as 30%.
- Conditions
- Unruptured Cerebral Aneurysm, Artificial Intelligence (AI), Subarachnoid Hemorrhage, Aneurysmal, Magnetic Resonance Angiography
- Trial name
- AI-CARE (NCT06766422)
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Airway Management
Airway Management With Supraglottic Devices in Unruptured Intracranial Aneurysms
Endovascular techniques for the treatment of intracranial aneurysms are growing.
- Trial name
- NCT03632902
- Testing
- supraglottic device
- Where
- Spain
- Volunteers
- 205 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Brain Neoplasms, Intracranial Aneurysm
Efficiency of Two Glucose Sampling Protocols for Maintenance of Euglycemia
What is the efficacy and safety of q 30 minutes vs. q 1hour glucose sampling and intervention for an intensive insulin protocol to achieve and maintain euglycemia in non-diabetic patients undergoing craniotomy? The investigators…
- Trial name
- NCT00993057
- Testing
- Insulin
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwestern University
Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Intracranial
Chemical and Mechanical Angioplasty for Vasospasm (SAVEBRAIN)
This is a monocentric randomized prospective trial comparing 2 different endovascular strategies of intracranial arterial angioplasty in case of refractory intracranial arterial vasospastic stenosis : chemical angioplasty…
- Conditions
- Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Intracranial, Stenosis, Ruptured Cerebral Aneurysm
- Trial name
- SAVEBRAIN (NCT05268445)
- Testing
- Chemical and Mechanical Angioplasty for Refractory Intracranial Arterial Vasospastic Stenosis
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Erasme University Hospital
Intracranial Non-saccular Aneurysms
Safety and Efficacy of the Flow Diverter in the Treatment of Intracranial Non-saccular Aneurysm
Using data obtained from the treatment of intracranial non-saccular aneurysms with flow diverter, evaluate the effecy and safety of blood flow diverter for the endovascular treatment of intracranial non-saccular aneurysms.
- Trial name
- SAEFD (NCT07205302)
- Testing
- flow diverter
- Volunteers
- 168 people
- Sponsor
- RenJi Hospital
Vasospasm, Cerebral, Aneurysmal Subarachnoid Hemorrhage
The Effect of Sympathetic Modulation on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage
The purpose of the study is to see that in addition to existing therapy, how well an additional procedure named spinal cord stimulation might reduce blood vessel spasm from aneurysm rupture.
- Trial name
- NCT06443177
- Testing
- Vectris trial leads and stimulation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama at Birmingham
Unruptured Intracranial Aneurysm
Treatment Strategies for Unruptured Intracranial Aneurysms in the Chinese Population China Treatment Trial for Unruptured Intracranial Aneurysm (ChTUIA)
The goal of this prospective observational cohort study is to learn about treatment strategies for unruptured intracranial aneurysms in the Chinese population.
- Trial name
- ChTUIA (NCT05844163)
- Testing
- observation
- Where
- China
- Volunteers
- 31,595 people
- Sponsor
- Beijing Tiantan Hospital
Arterial Aneurysm Wall Enhancement on HRMRI
Risk Assessment and Mechanism Analysis of Intracranial Multiple Aneurysm Instability Based on High-resolution Magnetic Resonance, Imaging Histology and Hemodynamics
This project proposes to establish a prospective cohort of MIA based on a preexisting multicenter MIA database and to combine multidimensional methods such as high-resolution magnetic resonance, hemodynamics, ambulatory blood…
- Trial name
- NCT06539767
- Where
- 2 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Zhujiang Hospital
Intracranial Aneurysm, Abdominal Aortic Aneurysm
UVA Brain and Aortic Aneurysm Study
The purpose of this study is to examine the percentage of patients who present with abdominal aortic aneurysms (AAA) will also have intracranial aneurysms (IA) and conversely; to examine the percentage of patients who present…
- Trial name
- BAAS (NCT02869464)
- Testing
- Imaging-Ultrasound, Imaging-MRA, DNA, RNA testing
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of Virginia
Cerebral Aneurysm Unruptured, Cerebral Aneurysm
Use of Classic LMA During Endovascular Therapy
Background: Earlier treatment and resolution for patients with cerebral aneurysms is now possible due to earlier diagnosis. This observational study aims to evaluate the intraoperative cardiovascular parameters in patients with…
- Conditions
- Cerebral Aneurysm Unruptured, Cerebral Aneurysm, Hemodynamic Instability, Airway Morbidity
- Trial name
- NCT03288519
- Volunteers
- 60 people
- Sponsor
- Universidad de Antioquia
Intracranial Aneurysms
Patients' Follow-up After Subarachnoid Haemorrhage Caused by Ruptured Intracranial Aneurysms
After endovascular treatment of the intracranial aneurysm, recanalization may occur, with a risk of recurrent subarachnoid haemorrhage or long-term angiographic recurrences of aneurysms.
- Trial name
- FUSAC (NCT02879175)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Intracranial Aneurysm
Reduction of Microembolism After the Intervention Surgery of Intracranial Aneurysms by Administration of Tirofiban
The goal of this clinical trial is to investigate whether intravenous injection of tilofiban can reduce microembolism in patients with unruptured intracranial aneurysms after Stent-Assisted Coil Embolization.The main questions it…
- Trial name
- NCT05841147
- Testing
- Tirofiban, normal saline
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Lu Hua
Subarachnoid Hemorrhage, Cerebral Aneurysm
Hypothalamo-, Pituitary-, Adrenal Axis Dysfunction in Subarachnoid Hemorrhage
Subarachnoid haemorrhage (SAH) may cause damage to the hypotalamo-pituitary-adrenal axis (HPA) thus disturbing the hormonal response of these structures.
- Trial name
- SAHENDO (NCT00614887)
- Where
- Finland
- Volunteers
- 46 people
- Sponsor
- Kuopio University Hospital
Kidney Transplant; Complications, Aneurysm, Brain
Evaluation of Nephrectomy Specimen for Intracranial Aneurysm Development in ADPKD
ADPKD is the most common form of hereditary kidney disease and is known to occur in 1 of 400 to 1000 population in the U.S. ADPKD consists of 2.8% of patients receiving kidney transplantation in the investigator's center.
- Conditions
- Kidney Transplant; Complications, Aneurysm, Brain, Polycystic Kidney Diseases
- Trial name
- NCT03889392
- Testing
- Kidney transplantation and nephrectomy
- Volunteers
- 154 people
- Sponsor
- Asan Medical Center