Clinical trials: Intracranial Arterial Aneurysm
Intracranial Aneurysm
AI for Detection of Brain Aneurysm: Low-cost Opportunistic Screening
The goal of this clinical trial is to verify the opportunistic screening potential of the AI software for detection of brain unruptured intracranial aneurysms (UIA) on routinely performed brain NECT scans in a prospective setting…
- Trial name
- AIDALOS-III (NCT07123818)
- Testing
- AI software
- Where
- 4 sites in Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ziekenhuis Oost-Limburg
Intracranial Aneurysms
Prospective Study of High-penetration Super-resolution Transcranial Ultrasound for Early Identification of Postoperative Intracranial Metallic Targets After Aneurysm Clipping
To evaluate the patient-level early diagnostic performance of high-penetration super-resolution transcranial ultrasound for identifying intracranial metallic targets, and to further assess clip-level detection, localization…
- Trial name
- HPSR-TCUS Clip (NCT07583225)
- Volunteers
- 78 people
- Sponsor
- Chinese PLA General Hospital
Subarachnoid Hemorrhage, Aneurysmal, Intracranial Aneurysm
Predictors of Rupture Risk of Intracranial Aneurysms
Patients admitted to Haukeland University Hospital with either UIA or aSAH underwent a measurement of bioelectrical impedance and body mass composition using InBody 10. Lipids and lipoproteins were collected from plasma.
- Trial name
- RAPID (NCT04613427)
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University of Bergen
Intracranial Aneurysm
Contour Neurovascular System - European Pre-Market Unruptured Aneurysm
Cerus Endovascular is sponsoring a prospective, multi-center trial to document the safety and performance of the Contour Neurovascular System™ ("Contour").
- Trial name
- CERUS (NCT03680742)
- Testing
- Contour Neurovascular System
- Where
- 6 sites in Austria, Denmark and 1 more
- Volunteers
- 34 people
- Sponsor
- Cerus Endovascular, Inc.
Intracranial Aneurysm
Prospective Study on Embolization of Intracranial Aneurysms With Pipeline™ Embolization Device
The purpose of this study is to assess the safety and effectiveness of the Pipeline™ device in the treatment of unruptured, wide-neck intracranial aneurysms.
- Trial name
- PREMIER (NCT02186561)
- Testing
- Pipeline™ Embolization Device/ Pipeline™Flex Embolization Device
- Where
- 23 sites in United States, Canada
- Volunteers
- 197 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Intracranial Aneurysm
pCONus Treatment of Wide Neck Intracranial Aneurysms
To assess safety and efficacy of pCONus for the treatment of wide neck bifurcation aneurysms.
- Trial name
- pToWin (NCT02554708)
- Testing
- implantation of the pCONus Bifurcation Aneurysm Implant
- Where
- 10 sites in Argentina, Austria and 3 more
- Volunteers
- 116 people
- Sponsor
- Phenox GmbH
Intracranial Aneurysm
Compare the Safety and Effectiveness of Two Different Kinds of Stent System in Intracranial Aneurysms
The primary objective of this trial is to evaluate the safety and efficacy of SINOMED IAS in patients with intracranial aneurysms.
- Trial name
- NCT06303063
- Testing
- SINOMED IAS Stent System, Neuroform Atlas Stent System
- Where
- 14 sites in China
- Volunteers
- 203 people
- Sponsor
- Sinomed Neurovita Technology Inc.
Intracranial Aneurysm
Complete Occlusion of Coilable Aneurysms
To compare the safety and effectiveness of Pipeline Embolization Device to coil embolization for the treatment of coilable wide-necked intracranial aneurysms
- Trial name
- COCOA (NCT00777907)
- Testing
- Pipeline Embolization Device (PED), Coil embolization
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Chestnut Medical Technologies
Intracranial Aneurysm
A Study of Choydar Flow-Directed Mesh Stent in the Treatment of Unruptured Intracranial Aneurysms
The purpose of this study is to assess how safe choydar flow-directed mesh stent is and how well it works in the treatment of unruptured intracranial aneurysms (a condition in which a bulging blood vessel in the brain can burst…
- Trial name
- CROWN (NCT07228312)
- Where
- 8 sites in China
- Volunteers
- 200 people
- Sponsor
- Johnson & Johnson Medical (Shanghai) Ltd.
Brain Aneurysm
Trial on Endovascular Aneurysm Management
The management of patients with unruptured aneurysms is controversial. Patients with unruptured aneurysms may suffer intracranial hemorrhage, but the incidence of this event is still debated.
- Trial name
- TEAM (NCT00537134)
- Testing
- Embolization, coiling
- Where
- 9 sites in United States, Canada and 2 more
- Volunteers
- 80 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Brain Aneurysm
CLinical EValuation of WEB 0.017 Device in Intracranial AneuRysms
The study is an observational, European, multi-center, prospective assessment of the clinical utility of the 0.017 WEB Aneurysm Embolization System in subjects with intracranial aneurysms deemed appropriate for endovascular…
- Trial name
- CLEVER (NCT03844334)
- Testing
- WEB Aneurysm Embolization System
- Where
- 4 sites in France, Germany and 1 more
- Volunteers
- 163 people
- Sponsor
- Microvention-Terumo, Inc.
Intracranial Aneurysm, Subarachnoid Hemorrhage
CorPath® GRX Neuro Study
The primary objective of this study is to evaluate the effectiveness and safety of robotic-assisted endovascular embolization procedures compared to objective performance criteria for traditional, manual operation based on the…
- Conditions
- Intracranial Aneurysm, Subarachnoid Hemorrhage, Headache
- Trial name
- NCT04236856
- Testing
- Robotic Endovascular Procedure
- Where
- 10 sites in Australia, Austria and 4 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Siemens Healthineers Endovascular Robotics, Inc.
Intracranial Aneurysm
Brain Low-risk Aneurysm Stereotactic Radiosurgical Trial
The goal of this clinical trial is to confirm the feasibility and safety of performing radiosurgery on unruptured, low-risk aneurysms in humans. Participants will choose if they want to undergo radiosurgery or not.
- Trial name
- BLAST (NCT06047951)
- Testing
- Stereotactic RadioSurgery (SRS)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Dr David Mathieu
Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Intracranial
Chemical and Mechanical Angioplasty for Vasospasm (SAVEBRAIN)
This is a monocentric randomized prospective trial comparing 2 different endovascular strategies of intracranial arterial angioplasty in case of refractory intracranial arterial vasospastic stenosis : chemical angioplasty…
- Conditions
- Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Intracranial, Stenosis, Ruptured Cerebral Aneurysm
- Trial name
- SAVEBRAIN (NCT05268445)
- Testing
- Chemical and Mechanical Angioplasty for Refractory Intracranial Arterial Vasospastic Stenosis
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Erasme University Hospital
Intracranial Aneurysms, Seizure
Seizure Prophylaxis in Aneurysm Repair
After a thorough review of the existing literature as well as a review of our own practice, the investigators have concluded that the decision to treat patients undergoing aneurysm repair with levetiracetam has reached true…
- Trial name
- SPAR (NCT01801072)
- Testing
- Levetiracetam
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Michigan
Cardiac Pacing, Artificial, Aneurysm, Brain
Rapid Ventricular Pacing During Cerebral Aneurysm Surgery: a Retrospective Study Concerning the Safety for Heart and Brain
Rapid ventricular pacing (RVP) is a technique to obtain flow arrest for short periods of time during dissection or rupture of the aneurysm. RVP results in an adequate fall of blood pressure which presents as an on-off phenomenon.
- Conditions
- Cardiac Pacing, Artificial, Aneurysm, Brain, Arteriovenous Malformations, Cerebral
- Trial name
- NCT03281395
- Testing
- Rapid ventricular pacing (RVP), No rapid ventricular pacing
- Where
- Belgium
- Volunteers
- 27 people
- Sponsor
- University Hospital, Antwerp
Subarachnoid Hemorrhage, Cerebral Aneurysm
Amnesia After Surgery for Anterior Communicating Aneurysm： High Resolution Magnetic Resonance (MR) Imaging Findings
To clarify whether amnesia after treatment of anterior communicating aneurysm (ACoA)is related to infarcts caused by occlusion or damage of the perforating artery of the ACoA, we used 3.0-T 3D high resolution MR imaging to…
- Conditions
- Subarachnoid Hemorrhage, Cerebral Aneurysm, Amnesia
- Trial name
- NCT01919775
- Volunteers
- 14 people
- Sponsor
- Tohoku University
Intracranial Aneurysm
Screening Intracranial Aneurysms With Magnetic Resonance Angiography (MRA) in China
The Chinese Cerebral Aneurysms Survey is a continuing prospective study among middle-aged and older individuals (35 - 75 years) that aims to determine the prevalence of cerebral intracranial aneurysms in the general population…
- Trial name
- NCT00926172
- Where
- China
- Volunteers
- 4,500 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Craniocerebral Trauma, Intracranial Aneurysm
Hypovitaminosis D in Neurocritical Patients
Vitamin D has been shown to impact prognosis in a variety of retrospective and randomized clinical trials within an intensive care unit (ICU) environment.
- Conditions
- Craniocerebral Trauma, Intracranial Aneurysm, Brain Neoplasms, Spinal Cord Injuries
- Trial name
- NCT02881957
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- University of Utah
Intracranial, Wide-Neck, Saccular Aneurysms
Study of the Enterprise Self-Expanding Stent System With Endovascular Coil Embolization of Wide- Neck Saccular Intracranial Artery Aneurysms
Cordis Self Expanding Stent for use with embolic coils for the treatment of wide-neck, intracranial, saccular aneurysms arising from a parent vessel
- Trial name
- NCT00233753
- Testing
- Cordis Neurovascular Self-Expanding Stent
- Volunteers
- 30 people
- Sponsor
- Codman & Shurtleff