Clinical trials: Intracranial Arterial Aneurysm
Intracranial Aneurysm
Study to Evaluate the Safety and Effectiveness of the CODMAN ENTERPRISE® Vascular Reconstruction Device
The purpose of this study is to demonstrate effectiveness and safety of the CODMAN ENTERPRISE® Vascular Reconstruction Device and Delivery System.
- Trial name
- NCT02532517
- Testing
- CODMAN ENTERPRISE® Vascular Reconstruction Device and Delivery System
- Where
- 11 sites in United States
- Volunteers
- 45 people
- Sponsor
- Cerenovus, Part of DePuy Synthes Products, Inc.
Intracranial Aneurysm
Medina Embolization Device In Neurovascular Aneurysm Study
A global prospective, multi-center, single-arm, post-market clinical follow-up (PMCF) study conducted to assess the performance of the Medina Embolization Device when used in unruptured and ruptured intracranial aneurysms.
- Trial name
- MEDINA (NCT02982200)
- Where
- 3 sites in Austria, Italy and 1 more
- Volunteers
- 15 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Cerebral Arteriovenous Malformation, Intracranial Arterial Diseases
Cerebral Arteriovenous Malformation With Aneurysm: Epidemiology, Clinical Features, and Prognosis
The study is a multicenter, prospective cohort study designed to assess the natural history, clinical safety and efficacy of various treatment strategies in patients with cerebral arteriovenous malformations (AVMs) and…
- Conditions
- Cerebral Arteriovenous Malformation, Intracranial Arterial Diseases, Intra Cerebral Hemorrhage, Intracranial Aneurysm
- Trial name
- NCT07353736
- Where
- China
- Volunteers
- 630 people
- Sponsor
- Duan Chuanzhi
Cerebral Aneurysm, Cerebral Aneurysm Unruptured
Parent Artery Reconstruction for Cerebral Aneurysms Using a Novel Flow Diverter With Surface Modification
The primary objective of this trial is to evaluate the safety and efficacy of the cerebral flow diverter in the endovascular treatment of wide-necked cerebral aneurysms
- Trial name
- NCT05774782
- Testing
- Cerebral flow diverter
- Where
- China
- Volunteers
- 143 people
- Sponsor
- Sinomed Neurovita Technology Inc.
Intracranial Aneurysm
INCA: Intracranial Aneurysm Treatment With NeXsys
Prospective, single center first-in-man study of use of device for intracranial aneurysm occlusion
- Trial name
- INCA (NCT02507531)
- Testing
- NeXsys Embolization System
- Where
- Argentina
- Volunteers
- 3 people
- Sponsor
- Cerus Endovascular, Inc.
Subarachnoid Hemorrhage
Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm
The purpose of the study is to examine the safety of a 14 day infusion of sodium nitrite, and to study the pharmacokinetics of nitrite, during a 14 day infusion in patients with ruptured cerebral aneurysms.
- Trial name
- NCT00873015
- Testing
- Sodium nitrite, Saline
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Hope Pharmaceuticals
Blood Pressure, Subarachnoid Hemorrhage
Blood Pressure Treatment in ICU Patients with Subarachniodal Haemorrhage.
An MRI study to examine the relationship between blood pressure and cerebral blood flow in patients with subarachnoidal hemorrhage and suspect or verified vasospasm.
- Conditions
- Blood Pressure, Subarachnoid Hemorrhage, Aneurysm Cerebral
- Trial name
- BFBP (NCT06033378)
- Testing
- Blood pressure elevation
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Umeå University
Ruptured Aneurysm of Intracranial Artery
DIVERT: Diversion of Flow in Intracranial VErtebral and Blood Blister-like Ruptured Aneurysms Trial: A Randomized Trial Comparing Pipeline Flow Diversion and Best-Standard-Treatment
The purpose of the DIVERT study is to provide a prudent, controlled clinical context for the use of flow diversion, a promising option of yet unproven benefit, in the care of patients with acute blood blister-like and dissecting…
- Trial name
- DIVERT (NCT01976026)
- Testing
- Flow Diversion, Best Standard Therapy
- Where
- Canada
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Subarachnoid Hemorrhage, Intracranial Aneurysm
Randomized, Double-blind, Placebo-controlled Trial to Investigate Safety and Efficacy of Cerebrolysin™ in Patients With Aneurysmal Subarachnoid Hemorrhage
This is a randomized, placebo-controlled, single-center clinical trial investigating the effectiveness of administrating intravenous Cerebrolysin™ (EVER NEURO Pharma, Austria), a preparation of low-molecular weight neurotrophic…
- Conditions
- Subarachnoid Hemorrhage, Intracranial Aneurysm, Delayed Cerebral Ischemia, Delayed Ischemic Neurological Deficit
- Trial name
- CESAR (NCT01787123)
- Testing
- Intravenous Cerebrolysin, Normal Saline
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Kwong Wah Hospital
Dissecting Aneurysm of Cerebral Artery
Dynamic Contrast-Enhanced Magnetic Resonance Imaging Analysis for Prognosis of Intracranial Dissecting Aneurysm With Intramural Hematoma After Endovascular Treatment
This study will evaluate the feasibility to predict the prognosis of IDA with IMH by DCE-MRI and provide theoretical basis for the prognosis and intervention of the disease.
- Trial name
- DEMAT (NCT03940859)
- Testing
- intracranial stent, flow diverter and coils
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Neurosurgical Institute
Aneurysm, Brain Aneurysm
Multimodal Biocollection Linked to the French Register of Intracranial Aneurysms
The purpose of the bCAN study is to create a prospective collection of multimodal data and human samples, linked to the French Intracranial Aneurysm Registry (FRAN).
- Conditions
- Aneurysm, Brain Aneurysm, Congenital Disease
- Trial name
- bCAN (NCT06689410)
- Testing
- blood or saliva sample
- Where
- 26 sites in France
- Volunteers
- 1,100 people
- Sponsor
- Nantes University Hospital
Brain Neoplasm, Intracranial Aneurysm
Subclavian Vein catheterization_Seldinger Vs Modified Seldinger
Seldinger technique is a minimally invasive technique in which the practitioner accesses the target vessel with a small bore needle, then dilates to the size required for the catheter.
- Conditions
- Brain Neoplasm, Intracranial Aneurysm, Cerebrovascular Moyamoya Disease
- Trial name
- MS (NCT02090010)
- Testing
- Seldinger technique, Modified Seldinger technique
- Where
- South Korea
- Volunteers
- 418 people
- Sponsor
- Seoul National University Hospital
Stent Embolisation
Efficacy and Safety of StENt-assisted Treatment for CErebral Aneurysms
Prospective registry study to evaluate safety and efficacy of stent assisted embolization of intracranial aneurysm.
- Trial name
- NCT01702584
- Testing
- stent assisted embolization
- Where
- Japan
- Volunteers
- 500 people
- Sponsor
- Kobe City General Hospital
Brain Aneurysm
Aneurysm Study of Pipeline in an Observational Registry
The primary objective of this study is to further expand the body of clinical knowledge in patients undergoing Pipeline Embolization Device (Pipeline or PED) placement for intracranial aneurysms (IAs or ICAs) according to…
- Trial name
- ASPIRE (NCT01557036)
- Testing
- Pipeline Embolization Device
- Where
- 36 sites in United States, Argentina and 6 more
- Volunteers
- 200 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Aneurism
Genetic Profile In Patients With Ruptured and Unruptured Intracranial Aneurysms
The project will involve multiple units within our Institute (Neurosurgery, Cerebrovascular Diseases, Neurology IV), as well as additional neurosurgical centers across Italy, for the enrollment of patients with saccular…
- Trial name
- ANEUBIO (NCT07233915)
- Where
- Italy
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Intracranial Aneurysm, Postoperative Pain
Effect of Bilateral Greater Occipital Nerve Block on Headache After Intracranial Aneurysm Coiling
Postoperative headache is a common complication following endovascular coil embolization of intracranial aneurysms and may increase analgesic requirements, impair patient comfort, and contribute to hemodynamic instability.
- Trial name
- NCT07910864
- Testing
- Ultrasound-Guided Bilateral Greater Occipital Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Konya City Hospital
Subarachnoid Aneurysm Hemorrhage, Unruptured Intracranial Aneurysm
Investigation of Protein Heterogeneity in Extracellular Vesicles Derived From Different Human Blood Circulatory Regions
The goal of this observational study is to learn about the protein heterogeneity in extracellular vesicles (EVs) derived from different human blood circulatory regions of patients with ruptured or unruptured intracranial…
- Trial name
- DBCR-EV-p (NCT07439965)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Hospital of Jilin University
Intracranial Aneurysm
Prediction of Development and Rupture Risk for Intracranial Unruptured Aneurysms
In recent years, researches on the natural history and risk factors of intracranial unruptured aneurysms have become a hot topic at home and abroad. However, risk factors for aneurysm rupture is still unclear yet.
- Trial name
- NCT05576727
- Testing
- Unruptured intracranial aneurysms
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cerebral Aneurysm
Decision Aids in Cerebral Aneurysm Treatment
Identifying and making a decision about the best health treatment or screening option can be difficult for patients. Decision aids can be used when there is more than one reasonable option, when no option has a clear advantage in…
- Trial name
- NCT02503553
- Testing
- Option grid for cerebral aneurysm treatment, Control
- Where
- United States
- Sponsor
- Dartmouth-Hitchcock Medical Center
Aneurysm Cerebral
Perioperative Risk in Patients on Chronic Aspirin Undergoing Craniotomy
This study is looking at how taking aspirin regularly affects bleeding during and after brain surgery. Specifically, it focuses on patients who are having elective surgery to clip a brain aneurysm.
- Trial name
- ASPRIN (NCT07086183)
- Testing
- Observation
- Where
- 3 sites in United States, Italy and 1 more
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic