Clinical trials: Intracranial Arterial Aneurysm
Intracranial Aneurysm
Pipeline Flex With SHield Technology Embolization - An International MulticEnter ObservationaL Post Market StuDy
This is a prospective, single-arm, multi-center post-market observational study assessing the performance of the Pipeline™ Flex Embolization Device with Shield Technology™ in subjects undergoing treatment for intracranial…
- Trial name
- SHIELD (NCT02719522)
- Testing
- Pipeline™ Flex Embolization Device with Shield Technology™
- Where
- 21 sites in Australia, Denmark and 9 more
- Volunteers
- 205 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Brain Aneurysms
International Retrospective Study of Pipeline Embolization Device
The primary objective of this retrospective study is to determine the incidence of important safety outcomes in patients who have undergone Pipeline Embolization Device placement for intracranial aneurysms (IAs).
- Trial name
- IntrePED (NCT01558102)
- Where
- 17 sites in United States, Argentina and 4 more
- Volunteers
- 793 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Aneurysms
The ENTERPRISE Study - Study of the Enterprise Self-Expanding Stent System
To evaluate the safety and feasibility of the Cordis Neurovascular Self-Expanding Stent System to facilitate endovascular coil embolization of wide neck saccular intracranial aneurysms.
- Trial name
- NCT00288405
- Testing
- Cordis Self Expanding Stent
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Codman & Shurtleff
Brain Aneurysm
Aneurysm Genetic Risk in Patients With QIB Changes
Intracranial aneurysm rupture is a leading cause of hemorrhagic strokes which carry high mortality and disability rates as well as high healthcare costs.
- Trial name
- AnGen (NCT05317169)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Intracranial Aneurysm
Diversion-p64 Post Market Clinical Follow-Up Study to Assess Safety and Effectiveness of the p64 Flow Modulation Device
The purpose of this study is to assess safety and effectiveness of the p64 Flow Modulation Device.
- Trial name
- NCT02600364
- Where
- 26 sites in Argentina, Belgium and 8 more
- Volunteers
- 450 people
- Sponsor
- Phenox GmbH
Cerebral Aneurysm
Valproic Acid, Magnesium Sulphate, Rocuronium Requirement, Postoperative Analgesia
The investigators hypothesized that valproic acid will increase rocuronium requirement and MgSO4 infusion would reduce requirement of muscle relaxant in craniotomy patients preloaded with sodium valproate.
- Trial name
- NCT01460563
- Testing
- Magnesium Sulfate, 0.9% saline
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Bundang Hospital
Cerebral Aneurysms, Intracranial Aneurysms
NOn-inVAsive Blood Pressure Monitoring in Intracranial Aneurysm Embolization
The goal of this clinical trial is to evaluate whether non-invasive continuous blood pressure monitoring (NVBP) using the ClearSight system can safely serve as an alternative to radial arterial catheterization for invasive…
- Conditions
- Cerebral Aneurysms, Intracranial Aneurysms, Coil Embolization, Hemodynamic Instability
- Trial name
- NOVA (NCT07246148)
- Testing
- Non-invasive continuous blood pressure monitoring, Invasive arterial blood pressure monitoring
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Korea University Anam Hospital
Blood Pressure, Subarachnoid Hemorrhage
Blood Pressure Treatment in ICU Patients with Subarachniodal Haemorrhage.
An MRI study to examine the relationship between blood pressure and cerebral blood flow in patients with subarachnoidal hemorrhage and suspect or verified vasospasm.
- Conditions
- Blood Pressure, Subarachnoid Hemorrhage, Aneurysm Cerebral
- Trial name
- BFBP (NCT06033378)
- Testing
- Blood pressure elevation
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Umeå University
Intracranial Aneurysm, Wide Neck Aneurysm, Large Neck Aneurysm, Lesion
Clinical Study of Merlin's DiVeRt - Vascular Reconstruction Device and Delivery System
The objective of the proposed investigation is to assess the safety and effectiveness of the Merlin's DiVeRt system for the treatment of intracranial lesions.
- Trial name
- NCT04589585
- Testing
- DiVeRt
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Merlin MD Pte Ltd
Aneurysm
A Feasibility Study of the Surpass Aneurysm-Embolization System in Intracranial Arteries
The purpose of this study is to evaluate safety and performance of the Surpass Aneurysm-Embolization System.
- Trial name
- NCT01101347
- Testing
- Aneurysm-Embolization System
- Volunteers
- 10 people
- Sponsor
- Surpass Medical Ltd.
Cerebral Arterial Aneurysm
Role of Propofol Postconditioning on Oxidative Stress and Cognitive Function
The purpose of this study was to evaluate differences between propofol postconditioning and sevoflurane anesthesia in the intracranial aneurysm surgery about antioxidant effect.
- Trial name
- NCT02691416
- Testing
- propofol postconditioning, sevoflurane
- Volunteers
- 60 people
- Sponsor
- The Third Central Clinical College of Tianjin Medical University
Aneurysm Cerebral
The TERUMO FRED X EARLY FEASIBILITY STUDY (FAST) STUDY.
The TERUMO FRED X EARLY FEASIBILITY STUDY (FAST) is a prospective, single-arm investigation.
- Trial name
- FAST (NCT07761598)
- Testing
- Fred X Medical Device Intervention for Aneurysm Treatment with DAPT Therapy.
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Jacobs institute
Wide-neck, Saccular Intracranial Aneurysms
The Penumbra Liberty Trial: Safety and Effectiveness in the Treatment of Wide-Neck Intracranial Aneurysms
To assess the safety and effectiveness of the Penumbra Liberty Stent System as adjunctive treatment to embolic coils for wide-neck, saccular, intracranial aneurysms in the internal carotid artery (ICA).
- Trial name
- NCT01636453
- Testing
- Stent assisted coiling with the Liberty Stent
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Penumbra Inc.
Dissecting Aneurysm of Cerebral Artery, Intramural Hematomas
Atorvastatin in the TREATment of Intracranial Unruptured VertebroBasilar Dissecting Aneurysms
This study was designed to whether there is a measurable reduction in inflammation in walls of unruptured vertebrobasilar dissecting aneurysms with atorvastatin.
- Conditions
- Dissecting Aneurysm of Cerebral Artery, Intramural Hematomas, Inflammation Vascular
- Trial name
- ATREAT-VBD (NCT04943783)
- Testing
- Atorvastatin 20mg
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Beijing Neurosurgical Institute
Aneurysms, Vascular Diseases
Researching AXIUM Coiling Experience and Recanalization (RACER)
The data collected in this study will be used to support International Regulatory submissions. The study objective is to evaluate the continued safety and efficacy of the AXIUM Progressive Coil System.
- Conditions
- Aneurysms, Vascular Diseases, Cerebrovascular Disorders, Intracranial Arterial Diseases
- Trial name
- RACER (NCT00703794)
- Testing
- The AXIUM Progressive Coil System
- Where
- 18 sites in United States
- Volunteers
- 119 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Brain Aneurysm
Safety and Effectiveness of an Intracranial Aneurysm Embolization System for Treating Large or Giant Wide Neck Aneurysms
This clinical research study is designed to determine safety and effectiveness of the Surpass Flow Diverter (Surpass System), an investigational device developed to treat wide-neck, large or giant intracranial aneurysms.
- Trial name
- SCENT (NCT01716117)
- Testing
- Surpass Flow Diverter
- Where
- 26 sites in United States, Netherlands
- Volunteers
- 213 people
- Sponsor
- Stryker Neurovascular
Cerebral Aneurysm, Thromboembolic Disease
Prospective, Single-Arm, Multicenter Study to Evaluate the Effectiveness and Safety of Endovascular Treatment in Patients With Cerebral Aneurysms Using P64 and P48 Flow-Diverter Stents
The use of flow-diverting stents for the endovascular treatment of cerebral aneurysms has proven to be effective and efficient in several clinical studies, leading to its widespread adoption.
- Trial name
- pSPAIN_HPC (NCT06201598)
- Testing
- Group 1 - Intervention 1
- Where
- 11 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario Central de Asturias
Intracranial Aneurysm, Stroke, Ischemic
Neurovascular Product Surveillance Registry
Post market surveillance registry
- Trial name
- INSPIRE (NCT02988128)
- Testing
- Treatment for intracranial aneurysms, Treatment for Acute Ischemic Stroke
- Where
- 99 sites in Argentina, Australia and 22 more
- Volunteers
- 4,000 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Intracranial Aneurysm
Tubridge Flow Diverter Study For Intracranial Aneurysms
The scope of this trial is the collection and analysis of the important safety outcomes in the real world, related to the use of the Tubridge flow diverter in the treatment of intracranial aneurysms.
- Trial name
- TRACE-IA (NCT05646108)
- Testing
- Endovascular treatment
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- MicroPort NeuroTech Co., Ltd.
Brain Neoplasm, Intracranial Aneurysm
Subclavian Vein catheterization_Seldinger Vs Modified Seldinger
Seldinger technique is a minimally invasive technique in which the practitioner accesses the target vessel with a small bore needle, then dilates to the size required for the catheter.
- Conditions
- Brain Neoplasm, Intracranial Aneurysm, Cerebrovascular Moyamoya Disease
- Trial name
- MS (NCT02090010)
- Testing
- Seldinger technique, Modified Seldinger technique
- Where
- South Korea
- Volunteers
- 418 people
- Sponsor
- Seoul National University Hospital