Clinical trials: Intracranial Arterial Diseases
Cerebral Amyloid Angiopathy, Intracerebral Hemorrhage Lobar
Colchicine for the Prevention of Recurrence in Cerebral Amyloid Angiopathy RElated IntraCerebral Hemorrhage
The goal of this clinical trial is to assess the safety and tolerability of colchicine for preventing intracerebral haemorrhage (ICH) recurrence in patients with cerebral amyloid angiopathy (CAA)-ICH at high risk of recurrence.
- Trial name
- CARE-ICH (NCT07026994)
- Testing
- Colchicine 0.5mg
- Where
- 3 sites in China
- Volunteers
- 80 people
- Sponsor
- Huashan Hospital
Intracranial Aneurysm
pCONus Treatment of Wide Neck Intracranial Aneurysms
To assess safety and efficacy of pCONus for the treatment of wide neck bifurcation aneurysms.
- Trial name
- pToWin (NCT02554708)
- Testing
- implantation of the pCONus Bifurcation Aneurysm Implant
- Where
- 10 sites in Argentina, Austria and 3 more
- Volunteers
- 116 people
- Sponsor
- Phenox GmbH
Alzheimer s Disease, Vascular Dementia
Predictors of Emergency Department Use in Frail Patients
When admitted to the emergency department (ED), elderly non-autonomous patients show high risk of adverse health outcomes. The prompt identification of ED use risk factors in such population is hence needed.
- Conditions
- Alzheimer s Disease, Vascular Dementia, Frailty, Elderly
- Trial name
- THE-Spoke 10 (NCT07259499)
- Testing
- Plasma phosphorylated Tau 181
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- University of Pisa
Cadasil
CADASIL Registry Study
The aim of this study is to determine the clinical spectrum and natural progression of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) and related disorders in a prospective…
- Trial name
- NCT04310098
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Bin Cai
Brain Aneurysm, Stroke
Safety and Efficacy of Aneurysms Treated With Endovascular Devices
In this project the investigators study the safety and efficacy of the recent endovascular devices used in treatment of brain aneurysms.
- Conditions
- Brain Aneurysm, Stroke, Intracranial Hemorrhages
- Trial name
- SEATED (NCT07175519)
- Testing
- Endovascular treatment of aneurysms
- Where
- United Kingdom
- Volunteers
- 5,000 people
- Sponsor
- King's College London
Intracranial Aneurysms
Pivotal Study of the LVIS (Low Profile Visualized Intraluminal Support)
The purpose of this study is to evaluate the safety and efficacy of the Low Profile Visualized Intraluminal Support(LVIS™ and LVIS™ Jr.)devices from MicroVention, Inc.
- Trial name
- LVIS (NCT01793792)
- Testing
- LVIS™ and LVIS™ Jr
- Where
- 21 sites in United States
- Volunteers
- 153 people
- Sponsor
- Microvention-Terumo, Inc.
Acute Stroke, Ischemic Stroke
Rescue Intracranial Stenting in Acute Ischemic Stroke
In acute ischemic stroke caused by intracranial large vessel occlusion, rescue intracranial stenting has been recently a treatment option to achieve recanalization in patients with the failure of mechanical thrombectomy.
- Conditions
- Acute Stroke, Ischemic Stroke, Intracranial Atherosclerosis, Stent Stenosis
- Trial name
- RISIS (NCT04986774)
- Testing
- Rescue intracranial stenting
- Where
- Vietnam
- Volunteers
- 85 people
- Sponsor
- Can Tho Stroke International Services Hospital
Intracranial Saccular Aneurysm, Either Rupture or Unruptured, Wide Neck Aneurysm
Solitaire Aneurysm Remodeling Registry
The objective of the registry is to evaluate the effectiveness and performance of the Solitaire Neurovascular Remodeling Device when used with embolic coils in the treatment of intracranial aneurysms.
- Trial name
- NCT04905303
- Where
- France
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Intracranial Aneurysm
MAXimizing Flow Diversion Effect On the Treatment of Large Intracranial Aneurysms With Embolization Devices
Investigate the ability of the intra-operative, intra-aneurysmal flow evaluation to assist with the treatment of intracranial large aneurysms using Embolization Device(s)
- Trial name
- MAX-PIPE (NCT03161769)
- Testing
- Neurovascular treatment of intracranial aneurysms, AneurysmFlow image processing software
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Chronic Stable Angina, Vascular Dementia
The Effect of Danzhu Fuyuan Granule as Adjunctive Therapy for Chronic Stable Angina, Vascular Dementia and Idiopathic Membranous Nephropathy: A Bayesian Basket Trial
This study is designed as a bayesian basket trial , which aims to evaluate the efficacy of Danzhu Fuyuan Granule in patients with Chronic Stable Angina, Vascular Dementia and Idiopathic Membranous Nephropathy
- Conditions
- Chronic Stable Angina, Vascular Dementia, Idiopathic Membranous Nephropathy
- Trial name
- NCT04498962
- Testing
- Danzhu Fuyuan Granule
- Where
- 7 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Jingqing Hu
Stable Angina, Unstable Angina
Serum Uric Acid Levels and Onset of Cardiovascular Diseases: a CALIBER Study
Serum uric acid level is a commonly measured biomarker. The association between serum uric acid level and the risk of developing cardiovascular diseases has been observed in some studies, while others showed controversial…
- Conditions
- Stable Angina, Unstable Angina, Myocardial Infarction, Unheralded Coronary Heart Disease Death
- Trial name
- NCT03425305
- Volunteers
- 180,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Moyamoya Disease
The Role of m6A RNA Modification in Moyamoya Disease
The purpose of this study is to detect the change of m6A RNA modification from peripheral blood of patients with moyamoya disease, and to assess the relationship between clinical characteristics.
- Trial name
- NCT04696094
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Dementia, Vascular
A Placebo-controlled Trial to Evaluate the Safety and Efficacy of Galantamine in the Treatment of Vascular Dementia
This is a trial to evaluate the safety and effectiveness of galantamine in patients with dementia secondary to blood vessel disease in the brain.
- Trial name
- NCT00035191
- Testing
- galantamine
- Volunteers
- 254 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Intracranial Aneurysms
Feasibility Study of the LVIS™ (Low-profile Visualized Intraluminal Support)Device
The purpose of this study is to evaluate the safety and probable benefit of the Low-profile Visualized Intraluminal Support (LVIS™ and LVIS™ Jr.)devices from MicroVention, Inc.
- Trial name
- LVIS (NCT01541254)
- Testing
- Low profile Visualized Intraluminal Device (LVIS and LVIS Jr.)
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Microvention-Terumo, Inc.
Aneurysm, Intracranial
An EFS Assessing the Electrolytic eCLIPs System for Treatment of Intracranial Aneurysms
The purpose of this study is to investigate the feasibility and initial clinical safety of eCLIPs device use for the treatment of wide-necked bifurcation aneurysms.
- Trial name
- NCT04886505
- Testing
- Electrolytic eCLIPs Bifurcation System
- Sponsor
- Evasc Medical Systems Corp.
Dementia, Dysphagia
Family Caregiver Online Survey (Dementia and Swallowing Difficulties)
The Family Caregiver Survey is a one-time, 30-minute, online survey for people living with and caring for a family member with dementia.
- Conditions
- Dementia, Dysphagia, Dementia Alzheimers, Dementia, Vascular
- Trial name
- NCT06471660
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Ischemic Stroke
External Counterpulsation Therapy for Severe Steno-occlusive Intracranial Stenosis
Intracranial stenosis is prevalent among Asians and constitute a common cause of cerebral ischemia. While the best medical therapy carries stroke recurrence rates in access of 10% per year, intracranial stenting was associated…
- Trial name
- NCT03921827
- Testing
- Enhance External Counterpulsation Therapy
- Where
- Singapore
- Volunteers
- 130 people
- Sponsor
- National University of Singapore
Subarachnoid Hemorrhage, Intracranial Aneurysm
Swiss Study on Subarachnoid Hemorrhage
This registry was created to assess management parameters of patients treated for aneurysmal subarachnoid hemorrhage in Switzerland.
- Trial name
- Swiss-SOS (NCT03245866)
- Testing
- Observational/ no intervention
- Where
- 9 sites in Switzerland
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Geneva
Aneurysm, Cerebral Aneurysm
Doppler Flow Wires in Cerebral Angiography
The purpose of this study is to use a wire with a Doppler tip to measure blood flow in vessels in the brain and determine hemodynamic factors associated with treatment success or failure.
- Trial name
- NCT03145701
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- University of Washington
Intracranial Aneurysm
FRED Retrospective Study of Intracranial Aneurysms Treatment
To evaluate the long-term safety and efficacy of Flow Re-Direction Endoluminal Device System (FRED) in the treatment of intracranial aneurysms in the post-market environment
- Trial name
- FRED (NCT06982781)
- Testing
- Flow Re-Direction Endoluminal Device System(FRED)
- Volunteers
- 2,000 people
- Sponsor
- Microvention-Terumo, Inc.
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