Clinical trials: Intracranial Arterial Diseases
Stroke, Middle Cerebral Artery Infarction
Gait Training for Persons With Stroke
The objective of this study is to investigate the effects of an automatic gait trainer (Lokomat) handled by physical therapists compared with categorized gait training by physical therapists in ambulatory stroke patients.
- Trial name
- GTS (NCT00612300)
- Testing
- Lokomat - Physical therapy, Physical therapy - Lokomat
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- University of Aarhus
Intracranial Aneurysm
Prevalence and Factors Associated With the Occurrence of Depression Six Months After an Endovascular Treatment of Intracranial Aneurysm
During the last decade, the embolization has become the treatment of choice for ruptured intracranial aneurysms, to improve the neurological outcome of patients.
- Trial name
- DEP-AIC (NCT02866812)
- Testing
- questionnaires assessing the state of fatigue, depression and anxiety
- Where
- France
- Volunteers
- 133 people
- Sponsor
- CHU de Reims
Intracranial Aneurysm
Aneurysmal Subarachnoid Hemorrhage and Superior Mesenteric Artery Flow Study
The purpose of this research study is to determine if the diameter and flow of the superior mesenteric artery in patients with aneurysmal subarachnoid hemorrhage undergoing hypertensive therapy for cerebral artery vasospasm are…
- Trial name
- NCT02684500
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Florida
Intracranial Aneurysm
Screening Intracranial Aneurysms With Magnetic Resonance Angiography (MRA) in China
The Chinese Cerebral Aneurysms Survey is a continuing prospective study among middle-aged and older individuals (35 - 75 years) that aims to determine the prevalence of cerebral intracranial aneurysms in the general population…
- Trial name
- NCT00926172
- Where
- China
- Volunteers
- 4,500 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Abdominal Aortic Aneurysm, Coronary Heart Disease NOS
Social Deprivation and Initial Presentation of 12 Cardiovascular Diseases: a CALIBER Study
Study of heterogeneity in associations between social deprivation and the initial presentation of 12 cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease NOS, Unheralded Corronary Death, Intracerebral Haemorrhage
- Trial name
- IP4 (NCT01937065)
- Testing
- No treatment
- Where
- United Kingdom
- Volunteers
- 1,937,360 people, healthy volunteers welcome
- Sponsor
- University College, London
Intracranial Aneurysm
Evolve China PMCF Study
A prospective, multi-center, single-arm, open-label, observational, post-market clinical follow-up. The expected duration of the study is 8 years (including up to 5-years' follow-up).
- Trial name
- NCT06368622
- Testing
- Surpass Evolve Flow Diverter System
- Where
- 24 sites in China
- Volunteers
- 500 people
- Sponsor
- Stryker Neurovascular
Brain Aneurysm
Safety and Effectiveness of an Intracranial Aneurysm Embolization System for Treating Large or Giant Wide Neck Aneurysms
This clinical research study is designed to determine safety and effectiveness of the Surpass Flow Diverter (Surpass System), an investigational device developed to treat wide-neck, large or giant intracranial aneurysms.
- Trial name
- SCENT (NCT01716117)
- Testing
- Surpass Flow Diverter
- Where
- 26 sites in United States, Netherlands
- Volunteers
- 213 people
- Sponsor
- Stryker Neurovascular
Ischemic Stroke, Transient Ischemic Attack
Regular Physical Exercise in Patients With Symptomatic Intracranial Arterial Stenosis
The objective of this study is to evaluate the effectiveness and safety of regular physical exercise in preventing ischemic stroke events in patients with symptomatic intracranial arterial stenosis.
- Trial name
- RESIST (NCT06615726)
- Testing
- Regular physical exercise, Control group
- Where
- 58 sites in China
- Volunteers
- 1,300 people
- Sponsor
- Capital Medical University
Moyamoya Disease, Remote Ischemic Preconditioning
Effects of Remote Ischemic Preconditioning With Postconditioning on Neurologic Outcome
In the present study, we evaluated whether RIPC with RIPostC reduce the major neurocomplication in patients undergoing STA-MCA anastomosis.
- Trial name
- NCT03072914
- Testing
- RIPC with RIPostC
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul National University Hospital
Intracranial Aneurysm
pCONUS2 Treatment of Wide Neck Intracranial Aneurysms 2
To assess safety and efficacy of pCONUS2 for the treatment of wide neck bifurcation aneurysms.
- Trial name
- pToWin2 (NCT03273478)
- Testing
- Endovascular treatment of bifurcation aneurysm with pCONUS2
- Volunteers
- 100 people
- Sponsor
- Phenox GmbH
Stroke, Ischemic, Mild Cognitive Impairment
Dapagliflozin Effect in Cognitive Impairment in Stroke Trial
Background: Dementia is an international public health problem, affecting approximately 50,000,000 people worldwide in 2018 and will triple by 2050; furthermore, reaching an approximate cost of 4 billion dollars.
- Conditions
- Stroke, Ischemic, Mild Cognitive Impairment, Dementia, Vascular, Metabolic Syndrome
- Trial name
- DECIST (NCT05565976)
- Testing
- Dapagliflozin 10mg Tab, Statins (Cardiovascular Agents), Platelet Antiaggregant
- Where
- Mexico
- Volunteers
- 270 people
- Sponsor
- Jaime Daniel Mondragon
Subarachnoid Hemorrhage, Aneurysmal, Subarachnoid Hemorrhage
Remote Ischemic Preconditioning in Subarachnoid Hemorrhage
Rupture of brain aneurysms is a common cause of death and disability, accounting for as many as 10% of stroke cases in the United States.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Subarachnoid Hemorrhage, Cerebral Vasospasm, Intracranial Aneurysm
- Trial name
- RIPC-SAH (NCT01158508)
- Testing
- Remote ischemic preconditioning
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Cerebral Arteriovenous Malformations
Treatment of Cerebral Arteriovenous Malformations With SQUID™ Liquid Embolic Agent
A non-interventional multicentric study for patients with a cerebral AVM for which endovascular treatment is indicated.
- Trial name
- NCT02602990
- Testing
- SQUID™
- Where
- 6 sites in Belgium, Germany
- Volunteers
- 50 people
- Sponsor
- Emboflu
Herpes Zoster (HZ), Vascular Dementia
A Study That Collects Participant Data and Biospecimens to Analyze Pathogenic Exosomes That Mediate Increased Vascular Dementia Risk in Individuals With Herpes Zoster.
The purpose of this observational research study is to study if patients with herpes zoster, also known as Shingles, have a higher risk of vascular dysfunction (problems with blood vessels, including stroke) and vascular dementia…
- Trial name
- R01 (NCT06903078)
- Where
- 2 sites in United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Center for Clinical Studies, Texas
Stroke
Impact of Verticalization on Intracranial Hemodynamics Assessed in Transcranial Doppler at the Acute Phase of Cerebral Infarction
The management of patients with ischemic stroke or transient ischemic attack is based on the preservation of a brain area by maintaining sufficient intracranial hemodynamics (IH) and with rapid recanalization.
- Trial name
- STAND (NCT03985059)
- Testing
- Transcranial Doppler
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Moyamoya Disease, Moyamoya
Imaging in Moyamoya Disease - Study to Investigate Different Imaging Technologies for a Better Understanding of Various Imaging Techniques to Evaluate Cerebral Hemodynamics, Disease-activity and Possibly the Etiology in Moyamoya Patients
Aim of this study is to improve patient care in Moyamoya Patients by improving Imaging technologies and aiming to identify factors involved in disease progression.
- Trial name
- IMAGINE (NCT06330818)
- Testing
- MRI, H2 15O PET/CT, Biosampling
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Intracranial Aneurysm
Compare the Safety and Effectiveness of Two Different Kinds of Stent System in Intracranial Aneurysms
The primary objective of this trial is to evaluate the safety and efficacy of SINOMED IAS in patients with intracranial aneurysms.
- Trial name
- NCT06303063
- Testing
- SINOMED IAS Stent System, Neuroform Atlas Stent System
- Where
- 14 sites in China
- Volunteers
- 203 people
- Sponsor
- Sinomed Neurovita Technology Inc.
Cerebral Aneurysm
Framing Eighteen Coils in Cerebral Aneurysms Trial
This trial is being conducted in order to compare angiographic outcomes in patients receiving 0.014-0.0155" platinum framing and filling coils (larger diameter coils) versus those treated solely with coils less than 0.014" (with…
- Trial name
- FEAT (NCT01655784)
- Testing
- Coil Embolization with larger Diameter Coils, Coil Embolization with Standard Diameter Coils
- Where
- 24 sites in United States
- Volunteers
- 651 people
- Sponsor
- Vanderbilt University Medical Center
Intracranial Arterial Diseases
Rosuvastatin Treatment for Intracranial Arterial Stenosis Based on Magnetic Resonance Angiography
The purpose of this study is to investigate the effects of rosuvastatin treatment on degree of intracranial arterial stenosis.
- Trial name
- NCT02341794
- Testing
- Rosuvastatin
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Tokyo Medical University
Cerebral Arteriovenous Malformation, Intracranial Arterial Diseases
Cerebral Arteriovenous Malformation With Aneurysm: Epidemiology, Clinical Features, and Prognosis
The study is a multicenter, prospective cohort study designed to assess the natural history, clinical safety and efficacy of various treatment strategies in patients with cerebral arteriovenous malformations (AVMs) and…
- Conditions
- Cerebral Arteriovenous Malformation, Intracranial Arterial Diseases, Intra Cerebral Hemorrhage, Intracranial Aneurysm
- Trial name
- NCT07353736
- Where
- China
- Volunteers
- 630 people
- Sponsor
- Duan Chuanzhi
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