Clinical trials: Intracranial Haemorrhage
Aneurysm, Subarachnoid Hemorrhage
SMCV Assessment on Brain Swelling in Patients With SAH
Cerebral swelling is a major complication following aneurysmal subarachnoid hemorrhage.This study is a retrospective cohort aimed to predict the extent of brain swelling.
- Conditions
- Aneurysm, Subarachnoid Hemorrhage, Brain Swelling
- Trial name
- Bayysmcv (NCT05696639)
- Testing
- Aneurysm embolization
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Shenzhen Baoan District People's Hospital
Head Injury, Subarachnoid Hemorrhage
Influence of Drainage on EVD ICP-signal
This observational study investigates ICP signals obtained through an external ventricular drain in the brain connected with an external transducer.
- Trial name
- NCT03164434
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stroke, Acute, Intracerebral Hemorrhage
The Akershus Study of Ischemic Stroke and Thrombolysis -1
This observational study comprises consecutively patients with cerebrovascular diseases admitted to the Stroke Unit at Akershus University Hospital in Norway.
- Conditions
- Stroke, Acute, Intracerebral Hemorrhage, Stroke, Ischemic, TIA
- Trial name
- ASIST-1 (NCT05378490)
- Where
- Norway
- Volunteers
- 6,000 people
- Sponsor
- University Hospital, Akershus
Aneurysmal Subarachnoid Hemorrhage
Prevention of Ischemia in Aneurysmal Subarachnoid Hemorrhage Through Remote Ischemic Preconditioning
Aneurysmal subarachnoid hemorrhage (SAH) is a severe form of stroke caused by bleeding around the brain. Despite early treatment of the initial hemorrhage, many patients develop delayed cerebral ischemia several days later, which…
- Trial name
- HMA (NCT07761520)
- Testing
- Remote Ischemic Preconditioning
- Volunteers
- 140 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Intracerebral Hemorrhage
Chinese Multicenter Cohort Study of Intracerebral Hemorrhage
Spontaneous intracerebral hemorrhage is a severe form of stroke associated with high mortality and long-term disability. The Chinese Multicenter Cohort Study of Intracerebral Hemorrhage (CASA) is a prospective observational…
- Trial name
- CMCS-ICH (NCT07833410)
- Where
- China
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Subarachnoid Hemorrhage, Aneurysmal, Intracranial Aneurysm
Predictors of Rupture Risk of Intracranial Aneurysms
Patients admitted to Haukeland University Hospital with either UIA or aSAH underwent a measurement of bioelectrical impedance and body mass composition using InBody 10. Lipids and lipoproteins were collected from plasma.
- Trial name
- RAPID (NCT04613427)
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University of Bergen
Hematoma, Subdural, Chronic
The Role of Meningeal Lymphatic Vessels in the Absorption of Chronic Subdural Hematoma and Its Injury Mechanism
Chronic subdural hematoma (CSDH) is a very common hemorrhagic disease of the nervous system, accounting for about 10% of hemorrhagic strokes.
- Trial name
- NCT05426889
- Testing
- subdural hematoma burr hole drainage, drug conservative treatment
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intracranial Hemorrhages
Safety and Efficacy of Remote Ischemic Conditioning for Spontaneous Intracerebral Hemorrhage
The purpose of this study is to determine the efficacy and safety of remote ischemic conditioning in treating acute intracerebral hemorrhage.
- Trial name
- NCT05609110
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Yi Yang
Subarachnoid Haemorrhage
Simvastatin in Aneurysmal Subarachnoid Haemorrhage (STASH) a Multicentre Randomised Controlled Clinical Trial
Intracranial bleeding from ruptured blood vessels (called a subarachnoid haemorrhage -SAH) affects 7000 patients each year in the UK and is a source of considerable death and disability, even in young adults.
- Trial name
- STASH (NCT00731627)
- Testing
- simvastatin
- Where
- 2 sites in United States
- Volunteers
- 803 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Intracerebral Hemorrhage, Motor Impairment
Fluoxetine for Motor Recovery After Acute Intracerebral Hemorrhage
This is a randomized, double-blind, placebo-controlled, multicenter clinical trial that will be carried out in Mexico. The purpose of this study is to test whether a 3-month treatment with fluoxetine enhances motor recovery in…
- Trial name
- FMRICH (NCT01737541)
- Testing
- Fluoxetine
- Where
- 4 sites in Mexico
- Volunteers
- 32 people
- Sponsor
- Universidad Autónoma de Aguascalientes
Subarachnoid Hemorrhage, Aneurysmal
Interest of Tissue Oxygen Pressure (PtiO2) Monitoring to Detect a Vasospasm Post Aneurysmal Subarachnoid Hemorrhage
Vasospasm is a current complication after aneurysmal subarachnoid hemorrhage and often and often associated with brain ischemia.
- Trial name
- O2-VASO (NCT03361722)
- Volunteers
- 10 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Subarachnoid Hemorrhage, Subarachnoid Hemorrhage, Aneurysmal
Ultra-early STatin in Patients With Aneurysmal subaRachnoid Hemorrhage (Ue-STAR)
A researcher-initiated and conducted multicenter, randomized controlled trial aimed at evaluating the efficacy and safety of ultra-early statin therapy in the treatment of acute aneurysmal subarachnoid hemorrhage (aSAH).
- Conditions
- Subarachnoid Hemorrhage, Subarachnoid Hemorrhage, Aneurysmal, Aneurysmal Subarachnoid Hemorrhage, Hemorrhage, Aneurysmal Subarachnoid
- Trial name
- Ue-STAR (NCT06559072)
- Testing
- Atorvastatin
- Where
- China
- Sponsor
- The George Institute
Intracerebral Hemorrhage
Effects and Mechanisms of Celecoxib on Intracerebral Hemorrhage
This trial is a phase IIa human clinical study, in which 60 patients with intracerebral hemorrhage (ICH) at basal ganglion or thalamus within 6 h after onset will be enrolled.
- Trial name
- NCT05434065
- Testing
- Celecoxib 200mg
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Brain Aneurysms
Remote Ischemic Pre-conditioning in Subarachnoid Hemorrhage
The purpose of the study is to investigate if briefly stopping blood flow to the patient's leg will lead to the patient's body being better able to tolerate possible decreased blood flow to regions of the brain which otherwise…
- Trial name
- RIPC-SAH (NCT02381522)
- Testing
- Remote Ischemic Pre-conditioning
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Loma Linda University
Aneurysmal Subarachnoid Hemorrhage
The Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage
The purpose of this phase II study is to further assess the safety of tiopronin in aneurysmal subarachnoid hemorrhage(aSAH) patients in order to obtain preliminary data on the efficacy of tiopronin versus placebo in reducing…
- Trial name
- NCT01095731
- Testing
- Tiopronin
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- E. Sander Connolly
Cerebral Hemorrhage, Intracranial Arteriovenous Malformations
MRI for the Early Evaluation of Acute Intracerebral Hemorrhage
What happens in the borderzone of a cerebral hemorrhage remains widely onknown and furhter the best timing for doing MR to look for vascular pathology in cerebral hemorrhage has not yet been determined.
- Conditions
- Cerebral Hemorrhage, Intracranial Arteriovenous Malformations, Intracranial Hemorrhage, Hypertensive, Brain Neoplasms
- Trial name
- NCT01689402
- Testing
- MRI Scan with the specified sequences below:
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Bispebjerg Hospital
Subarachnoid Hemorrhage
HyperHAES Versus Placebo - Effect on Intracranial Pressure in SAH Patients
The purpose of this study is to determine whether 7.2% NaCl in 6% hydroxyethyl starch will lower intracranial pressure (ICP) in SAH-patients with normal or moderately elevated ICP in a placebo controlled study, and to describe…
- Trial name
- NCT00199706
- Testing
- 7.2% NaCl in 6% hydroxyethyl starch solution
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Intra Cerebral Hemorrhage, Stroke
Ultra-Early, Minimally inVAsive intraCerebral Haemorrhage evacUATion Versus Standard trEatment
A randomized controlled trial of ultra-early, minimally invasive, hematoma evacuation versus standard care within 8 hours of intracerebral hemorrhage.
- Trial name
- EVACUATE (NCT04434807)
- Testing
- Minimally invasive hematoma evacuation
- Where
- 13 sites in Australia
- Volunteers
- 240 people
- Sponsor
- University of Melbourne
Ischemic Stroke, Haemorrhagic Stroke
COAgulation Disorders in Ischaemic and Haemorrhagic Stroke
In this study the investigators will assess both procoagulant and anticoagulant pathways using thrombin generation and platelet function tests; as well as neuronal ischemia using cell free DNA in all patients presenting with…
- Conditions
- Ischemic Stroke, Haemorrhagic Stroke, Aneurysmal Subarachnoid Hemorrhage
- Trial name
- COADIHS (NCT05974111)
- Testing
- blood sampling
- Where
- Belgium
- Volunteers
- 379 people
- Sponsor
- Ziekenhuis Oost-Limburg
Intracerebral Hemorrhage
Simvastatin For Intracerebral Hemorrhage Study
Study Objective: To analyze if statins are effective in ameliorating perihematomal edema evolution thereby reducing mortality and improving functional outcomes following spontaneous intracerebral hemorrhage (ICH).
- Trial name
- NCT00718328
- Testing
- Simvastatin 80 mg
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Johns Hopkins University