Clinical trials: Intracranial Surgery
Intracerebral Haemorrhage (ICH)
Surgical Evacuation Of Spontaneous Intracerebral Hematoma: Clinical Outcomes and Prognostic Factors
The aim of this study is to assess the safety and efficacy of surgical evacuation of spontaneous intracerebral hemorrhage.
- Trial name
- NCT06816641
- Testing
- Surgical Evacuation of Intracerebral Hemorrhage
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Ischemic Stroke, Brain Tumor
Confounding Factors in the Detection of Intracranial Hemorrhage With the Infrascanner
The investigators prospectively want to use the Infrascanner in patients with ischemic stroke, patients with brain surgery, patients with brain tumors, patients with intracranial hemorrhage and patients with a normal CT scan of…
- Conditions
- Ischemic Stroke, Brain Tumor, Brain Surgery, Intracranial Hemorrhage
- Trial name
- NCT02809651
- Testing
- Infrascanner
- Where
- Belgium
- Volunteers
- 89 people
- Sponsor
- Ziekenhuis Oost-Limburg
Intracerebral Hemorrhage Basal Ganglia, Intracerebral Haemorrhage
Minimally Invasive Surgery For Patients With Spontaneous Deep Intracerebral Hemorrhage
This observational cohort study evaluates the safety and effectiveness of minimally invasive surgery (MIS) compared with standard medical management in adults with spontaneous deep intracerebral hemorrhage.
- Trial name
- MISDIH (NCT07234955)
- Where
- Vietnam
- Volunteers
- 300 people
- Sponsor
- Huynh Quoc Huy
Intracranial Hemorrhage
INVEST Feasibility - Minimally Invasive Endoscopic Surgery With Apollo in Patients With Brain Hemorrhage
The primary objective of this multicenter single arm feasibility study is to provide an assessment of enrollment and follow up feasibility for this patient population being treated with the Apollo Minimally Invasive Surgical…
- Trial name
- NCT02654015
- Testing
- Apollo MIES, Medical Management
- Where
- 7 sites in United States
- Volunteers
- 50 people
- Sponsor
- J. Mocco
Procedural Pain
To Explore the Optimal Dose of Alfentanil for Skull Pin Fixation in Intracranial Surgery
Forty patients were enrolled, and all patients used total intravenous anesthesia (alfentanil-propofol based TIVA) as anesthesia induction and maintenance.
- Trial name
- NCT06563297
- Testing
- Alfentanil
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Extracorporeal Life Support
Optic Nerve Sheath Diameter and the Duration of Extracorporeal Life Support During Newborn Cardiac Surgery
Mortality rates for newborns with congenital heart disease (CHD) have dramatically decreased thanks to surgical methods and medical treatment improvements.
- Trial name
- NCT05930691
- Testing
- Optic nerve sheath diameter measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Konya City Hospital
Cerebral Hemorrhage, Head Injury
Biomarkers Correlation With Volemia
The purpose of this study is to determine whether the Biomarkers (pro adrenomedullin (MR proADM), pro arginin vasopressin (CT proAVP), pro atrial natriuretic peptid (MR proANP), Pro Endothelin) changes at Day 2, Day 5 and Day 7…
- Conditions
- Cerebral Hemorrhage, Head Injury, Non Traumatic Post Surgery, Poly Trauma Patients Without Heart Failure
- Trial name
- ENVOL (NCT01858675)
- Testing
- Biomarkers, red blood cells and plasma assessment
- Where
- France
- Volunteers
- 66 people
- Sponsor
- ThermoFisher Scientific Brahms Biomarkers France
Chronic Subdural Hematoma
Middle Meningeal Artery Embolisation in Chronic Subdural Hematoma
This international multicenter study evaluates the efficacy and safety of middle meningeal artery embolization (MMAE) using PVA particles or liquid embolic agents as a perioperative treatment to prevent the recurrence of chronic…
- Trial name
- EMMA-CS (NCT07751887)
- Testing
- Middle Meningeal Artery Embolisation
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital Hradec Kralove
Intracranial Hypertension
Effects of Extracorporeal Circulation Techniques on Cerebral Perfusion in CABG Surgery
This prospective study aims to compare the effects of minimal invasive extracorporeal circulation (MiECC) and conventional reservoir-based extracorporeal circulation techniques on cerebral perfusion in patients undergoing…
- Trial name
- NCT07420738
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kartal Kosuyolu High Speciality Training and Research Hospital
Intracranial Hemorrhage, Hypertensive
Minimally-invasive Surgery Versus Craniotomy in Patients With Supratentorial Hypertensive Intracerebral Hemorrhage
The effectiveness of craniotomy in the treatment of intracerebral hemorrhage remains controversial. Two main types of minimally invasive surgery, endoscopic evacuation and stereotactic aspiration, have been attempted for hematoma…
- Trial name
- MISICH (NCT02811614)
- Testing
- Endoscopic Evacuation, Stereotactic Aspiration, Craniotomy
- Where
- China
- Volunteers
- 733 people
- Sponsor
- Chinese PLA General Hospital
Cerebral Aneurysm, Arteriovenous Malformations
Exploration of Anticoagulation Program in Cerebral Aneurysm and Arteriovenous Malformations With Hybrid Operation 2
In the stage of randomized controlled study, our purpose is to obtain the Intraoperative anticoagulation program supported by evidence-based medicine.
- Trial name
- EAPCAAMHO2 (NCT03306836)
- Testing
- Heparin Sodium
- Where
- China
- Volunteers
- 408 people
- Sponsor
- Beijing Tiantan Hospital
Unruptured Intracranial Aneurysms
Brain Lesions Following Endovascular and Surgical Treatment of Unruptured Intracranial Aneurysms
The purpose of this study is to determine the incidence and impact of brain lesions in MRI after coiling and clipping of unruptured intracranial aneurysms on clinical and neurological outcome of patients.
- Trial name
- LESUIA (NCT01490463)
- Where
- Germany
- Sponsor
- Johann Wolfgang Goethe University Hospital
Pseudotumor Cerebri, Idiopathic Intracranial Hypertension (IIH)
Operative Procedures Vs. Endovascular Neurosurgery for Untreated Pseudotumor Trial
Pseudotumor cerebri, also called idiopathic intracranial hypertension (IIH), is characterized by elevated intracranial pressure, headache, and if severe, vision loss. IIH is difficult to treat.
- Trial name
- OPEN-UP (NCT02513914)
- Testing
- Dural Venous Sinus Stenting, Cerebrospinal Fluid Shunting
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Optic Nerve Cup, Intracranial Pressure Increase
Effect of Lithotomy Position on Optic Nerve Sheath Diameter
In this study, the effect of increased venous return and increased intra-abdominal pressure on intracranial pressure in the lithotomy position was evaluated.
- Trial name
- NCT06464419
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Brain Neoplasm
Single Dose Tramadol Effect on Extubation Response and Quality of Emergence Post-supratentorial Intracranial Surgery
Several modalities have been studied to prevent coughing during emergence, including extubation in a deep plane of anesthesia but have proved to be unreliable. So far, no reliable method is recommended as standard of care.
- Trial name
- NCT02964416
- Testing
- Injection Tramadol
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Aga Khan University
Postoperative Cognitive Complications, Delirium
Prospective Observational Multimodal Neuromonitoring During High-Risk Adult Surgery
This is a prospective observational cohort study of adult patients undergoing high-risk surgery at UT Southwestern Medical Center.
- Conditions
- Postoperative Cognitive Complications, Delirium, Perioperative/Postoperative Complications, Brain Injuries
- Trial name
- NCT07577726
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas Southwestern Medical Center
Stroke, Transient Ischemic Attack
The "COSMOS"-Study (Copeptin in Osmoregulation and Stress Assessment)
Sodium imbalance is common and an adverse prognostic factor in hospitalized patients. However, identifying the causes of sodium imbalance is challenging in clinical practice.
- Trial name
- NCT00390962
- Where
- Switzerland
- Volunteers
- 469 people
- Sponsor
- University Hospital, Basel, Switzerland
Pituitary Adenoma
Semi-sitting Versus Supine Position in Endoscopic Skull Base Surgery
This study is to prospectively compare the standard supine (control group) and the semi-sitting position (head elevation of 30°; intervention group) in endoscopic endonasal pituitary surgery.
- Trial name
- PosESS (NCT04584866)
- Testing
- Endonasal endoscopic pituitary surgery in semi-sitting position, Endonasal endoscopic pituitary surgery in supine position
- Where
- Switzerland
- Volunteers
- 54 people
- Sponsor
- University Hospital, Basel, Switzerland
AVM (Arteriovenous Malformation) Intracranial
Cerebral Vascular Malformations: From Multimodal Imaging, to Endovascular, Surgical or Combined Treatment
Cerebrovascular malformations (CVMs) are a heterogeneous group of disorders and can be classified histopathologically into five main categories: arteriovenous malformations (AVMs), dural arteriovenous fistulas (AVDs)…
- Trial name
- NCT05729295
- Testing
- Endovascular embolization or surgery
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
INTRACRANIAL TUMOR, INTRACRANIAL PRESSURE
Evaluation of Postoperative Intracranial Pressure in Patients Undergoing Intracranial Tumor Surgery
Ultrasonography(USG)-guided optic nerve sheath diameter measurement and its correlation with brain computed tomography in the evaluation of intracranial pressure in patients who underwent intracranial brain tumor surgery.
- Conditions
- INTRACRANIAL TUMOR, INTRACRANIAL PRESSURE, OPTIC NERVE
- Trial name
- NCT06559566
- Testing
- USG, BCT
- Volunteers
- 50 people
- Sponsor
- Sezen Kumaş Solak