Clinical trials: Intractable Chronic Migraine
Refractory Chronic Migraine
Treatment of Chronic Migraine With Erenumab Alone or as an Add on Therapy
Treatment of chronic migraineurs who have failed more than 3 preventive drugs with Erenumab alone, to reduce frequency of monthly migraine days or as an add on therapy
- Trial name
- NCT04152434
- Testing
- Erenumab Auto-Injector
- Where
- Canada
- Volunteers
- 158 people
- Sponsor
- Clinique des Céphalées de Montréal
Migraine, Headache
Ticagrelor Therapy for RefrACTORy Migraine Study
This is a prospective, open-label, single-arm pilot study treating 40 subjects to assess the hypothesis that P2Y, G protein-coupled 12 (P2Y12) inhibition with Brilinta/ticagrelor (90 mg by mouth (PO) twice a day) reduces episodic…
- Conditions
- Migraine, Headache, Migraine Headache
- Trial name
- TRACTOR (NCT02518464)
- Testing
- Ticagrelor 90 mg twice per day
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Columbia University
Migraine, Headache Disorders, Primary
Efficacy of Greater Occipital Nerve Radiofrequency for Refractory Migraine Treatment
Objective: Ultrasound-guided pulsed radiofrequency therapy can be used on the greateroccipital nerve (GON) in patients with chronic migraine (CM) who are unresponsive to conservative treatments.
- Trial name
- NCT05199064
- Testing
- Ultrasound guided greater occipital nerve (GON) radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Chronic Migraine, Medication Overuse Headache
Effects of Transcranial Direct Current Stimulation in Refractory Chronic Migraine and Medication-overuse Headache
The purpose of the study is to evaluate the efficacy of the transcranial direct current stimulation of the primary motor cortex (M1) in patients affected by refractory chronic migraine (coded as 1.5.1 in the international…
- Trial name
- NCT01752439
- Testing
- Anodal transcranial direct current stimulation
- Volunteers
- 30 people
- Sponsor
- Dr Armando Perrotta, MD, PhD
Migraine, Chronic Migraine Headache
Bilateral Embolization of the Middle Meningeal Arteries for Refractory Chronic Migraine
This study is to test the safety and feasibility of a procedure called embolization of the middle meningeal arteries (MMA), using a product called Onyx. Embolization creates a plug in the arteries.
- Conditions
- Migraine, Chronic Migraine Headache, Refractory Migraine
- Trial name
- MMAE-Migraine (NCT07223008)
- Testing
- embolization of middle meningeal arteries
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Johns Hopkins University
Chronic Pain
Home-based Transcranial Stimulation in the Treatment of Patients With Refractory Chronic Pain
Refractory chronic pain represents a serious and limiting health condition which does not respond to standard pharmacological therapy.
- Trial name
- NCT05099406
- Testing
- Transcranial electrical stimulation
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Santiago de Compostela