Clinical trials: Intraocular Lens
Cataract
Presbyopia-Correcting Intraocular Lenses (IOLs)
The purpose of this study is to prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with Presbyopia-Correcting Intraocular Lenses (IOLs).
- Trial name
- NCT00963560
- Testing
- ReSTOR +3, Crystalens HD, Crystalens AO
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Alcon Research
Cataract
Prospective Clinical Study of Unilateral or Bilateral Implantation of Intraocular Lens in Cataract Patients
This is to evaluate the satisfaction of patient and postoperative functional vision of unilateral or bilateral Implantation of intraocular lens（IOLs） in cataract patients.
- Trial name
- NCT04265820
- Testing
- unilateral implantation of IOL, bilateral implantation of IOL
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Capsular Contracture, Implant, Pediatric Cataract
Capsular Outcomes of Pediatric Cataract Surgery With Primary Intraocular Lens Implantation
Lens capsular often changes after pediatric cataract surgery，causing complications such as anterior capsulerhexis shrinkage, visual axis opacification (VAO), zonular dehiscence and so on.
- Trial name
- capsular (NCT04803097)
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Yune Zhao
Primary Open Angle Glaucoma
24h Continuous Intraocular Pressure (IOP) Monitoring vs Goldmann Applanation Tonometry
A study in which intraocular pressure (IOP) will be monitored over 24 hours using the SENSIMED Triggerfish® device and Goldmann applanation tonometry (GAT) in primary open angle glaucoma patients.
- Trial name
- NCT01217853
- Testing
- SENSIMED Triggerfish
- Where
- 2 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Sensimed AG
Astigmatism
Comparison of Clinical Outcomes of Toric Intraocular Lens
This study is to compare the clinical outcome of Precizon toric intraocular lens(IOL) to that of Tecnis toric IOL.
- Trial name
- NCT03085901
- Testing
- Precizon toric intraocular lens, Tecnis toric intraocular lens
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Cataract
Postoperative Rotational Dynamics of Three Toric Intraocular Lens Designs
This prospective comparative cohort study evaluates and compares postoperative rotational stability and time-course dynamics of three commercially available toric intraocular lenses (TECNIS Toric II [ZCU], AcrySof IQ Toric, and…
- Trial name
- 3 TORIC ROTATE (NCT07453992)
- Testing
- TECNIS Toric II (ZCU), AcrySof IQ Toric, AT TORBI 709M
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jin Yang
Congenital Cataract
Comparison of Minimal Invasive Lens Surgery and Traditional Cataract Surgery
Previously, we have developed a minimal invasive lens surgery in the purpose of reduce post-operative complications of congenital cataract.
- Trial name
- NCT03230799
- Testing
- minimal invasive lens surgery, traditional cataract surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Cataract
Surgeon Experience ReSTOR A +4 Intraocular Lens (IOL)
To collect visual outcome data post AcrySof ReSTOR Aspheric +4 implantation from surgeons throughout the United States.
- Trial name
- NCT00733512
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Alcon Research
Secondary Cataract Surgery, Aphakia
Comparison of Two Different Intraocular Lenses Implanted With Yamane Technique
In case of instability or rupture of capsular bag occurs during cataract surgery, Yamane technique is one of the options to fix intracocularlens' haptics.
- Conditions
- Secondary Cataract Surgery, Aphakia, Complicated Cataract Surgery
- Trial name
- NCT05912829
- Testing
- IOL Master 700, Casia-2, MS-39
- Where
- 2 sites in Austria
- Volunteers
- 50 people
- Sponsor
- Johannes Kepler University of Linz
Cataract, Lens Opacities
Rotational Stability Analysis of a Toric Monofocal IOL
This is a single-center, prospective PMCF study whereby patients undergoing routine cataract surgery will have monolateral implantation of hydrophilic monofocal toric intraocular lens Ankoris.
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- PHY2013 (NCT04933487)
- Testing
- IOL implantation experimental
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract, Intraocular Lens Implantation
The Femtosecond Laser in Residency Training (FLIRT) Pilot Study
This pilot study aims to primarily assess the rate of complication of anterior vitrectomy for patients undergoing femtosecond laser-assisted (FLA) cataract extraction and intraocular lens placement (CEIOL) compared to manual…
- Trial name
- FLIRT (NCT03115216)
- Testing
- FLA-CEIOL, CEIOL
- Sponsor
- University of Southern California
Cataract
Clinical Behavior of the Asqelio™ Trifocal Diffractive Intraocular Lens
The main objective of this study was to evaluate distance, intermediate, and near vision in patients who have undergone cataract extraction with bilateral implantation of a new hydrophobic trifocal diffractive intraocular lens…
- Trial name
- NCT05776446
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- AST Products, Inc.
Cataract, Astigmatism
Evaluation of Toric Intraocular Lens(IOL) Combined With Capsular Tension Ring(CTR) in Patients With Cataract Combined With High Myopia
The objective of this study is to evaluate the postoperative visual quality and IOL stability in patients with cataracts and high myopia who have undergone surgery using astigmatism-correcting IOLs in conjunction with tension…
- Conditions
- Cataract, Astigmatism, Intraocular Lens Rotation
- Trial name
- NCT06571773
- Testing
- intraoperative implantation of Capsular Tension Ring, none intraoperative implantation of CTR
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Shanghai 10th People's Hospital
Cataract
Level of Agreement of Intraocular Lens Power Measurements Between IOLMaster and Verion
Primary objective of this study is to evaluate the level of agreement of two keratometry modules, the IOLMaster and the Verion Reference Unit, in terms of keratometric values and IOL power calculation.
- Trial name
- NCT03876782
- Testing
- IOLMaster, Verion
- Where
- Greece
- Volunteers
- 54 people
- Sponsor
- Democritus University of Thrace
Cataracts
Clinical Investigation of the TECNIS® Next-Generation Intraocular Lens, Model DEN00V
Prospective, multicenter, bilateral, masked (sponsor, subject and evaluator), randomized clinical trial to evaluate the safety and effectiveness of the TECNIS IOL, Model DEN00V in comparison to an aspheric monofocal IOL.
- Trial name
- NCT05574959
- Testing
- investigational IOL Model DEN00V, control IOL Model ZCB00/DCB00
- Where
- 10 sites in United States
- Volunteers
- 243 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract
AMO's Tecnis™ Multifocal Intraocular Lenses (Tecnis MF), Alcon's ReStor Multifocal IOL
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR IOLs Six months post cataract surgery.
- Trial name
- NCT01278420
- Testing
- Tecnis MF, ReSTOR
- Where
- 6 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Fuch's Endothelial Dystrophy, Cataracts
Study of the Effect of Aspheric Lenses in Patients With Fuch's Dystrophy
The proposed study will recruit patients with mild to moderate Fuch's dystrophy who need cataract surgery alone. They will be randomly assigned to receive either spheric or aspheric lenses.
- Trial name
- NCT02109276
- Testing
- Spheric Sensar(R) 3-piece IOL, Aspheric Tecnis(R) 3-piece IOL
- Where
- Canada
- Sponsor
- Queen's University
Intraocular Lens, Cataract
Evaluation of Safety and Effectiveness of an IOL With a Virtual Aperture Optic
Cataracts are cloudy areas in the lens of the eye that can cause changes in vision. Symptoms of cataracts include cloudy or fuzzy vision and sensitivity to glare.
- Conditions
- Intraocular Lens, Cataract, Presbyopia
- Trial name
- NCT05955846
- Testing
- cataract surgery, implantation of device IOL FG-80030.1
- Where
- 8 sites in Portugal, Spain and 1 more
- Volunteers
- 60 people
- Sponsor
- Z Optics, Inc.
Cataract, Pseudophakia
Clinical Investigation of the Safety and Performance of Model 690AD and Model 690ADY Monofocal Intraocular Lens Implantation
Medicontur hydrophilic posterior chamber monofocal intraocular lens (IOLs) are indicated to improve vision at far distance in adults with cataract and/or ametropia (hyperopia, myopia), secondarily to removal of the crystalline…
- Conditions
- Cataract, Pseudophakia, Intraocular Lens Complication, Intraocular Lens Opacification
- Trial name
- NCT05750225
- Testing
- Standard of care, Patient satisfaction questionnare
- Where
- 2 sites in Hungary
- Volunteers
- 52 people
- Sponsor
- Medicontur Medical Engineering Ltd
VR-based Informed Consent, Cataract and Intraocular Lens Surgery
VR for Cataract Anxiety Lowering Management
Cataract is currently the leading cause of blindness globally, and surgery is the only effective treatment. With the advancement of medical technology, cataract surgery is usually performed under topical anesthesia, which means…
- Trial name
- VR-CALM (NCT07586280)
- Testing
- Virtual reality simulation of intraoperative audiovisual experience
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine