Clinical trials: Intraocular Lens Implant
Cataract
Clinical Evaluation of the Performance of the enVista® Aspire™ (EA) Lens
A Prospective, Single-Center, Randomized Clinical Investigation to evaluate the safety and performance of the enVista® Aspire ™ (EA) intraocular lens (IOL) when compared to the MX60E monofocal IOL (control lens) and an IOL with a…
- Trial name
- NCT06479148
- Testing
- enVista® Aspire™, An IOL with a slightly extended depth of focus, MX60E
- Where
- Honduras
- Volunteers
- 27 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Evaluation of Visual Acuity and Patient Satisfaction With AT LISA TRI 839MP Intraocular Lenses
The purpose of the study is to evaluate the far, intermediate and near visual acuities with a trifocal IOL.
- Trial name
- NCT01731743
- Testing
- AT LISA tri 839MP
- Where
- Germany
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Pseudophakia
Effect of Optic Edge Design in a Silicone Intraocular Lens on Posterior Capsule Opacification
Purpose: To compare the posterior capsule opacification (PCO) inhibiting effect of the sharp posterior optic edge design of the Clariflex silicone intraocular lens (IOL) with that of the double-round edge design of the SI40…
- Trial name
- NCT00428363
- Testing
- Cataract surgery with implantation of an intraocular lens
- Where
- Austria
- Volunteers
- 52 people
- Sponsor
- Medical University of Vienna
Cataract
Post-Market Clinical Survey of Clareon® IOL AutonoMe™ in Japanese Subjects
This purpose of this survey study is to collect and describe clinical outcomes for the intraocular lens (IOL) delivery performance of Clareon® IOL AutonoMe™ when used in daily practice.
- Trial name
- NCT03824028
- Testing
- Clareon® IOL AutonoMe™ automated preloaded delivery system
- Where
- 3 sites in Japan
- Volunteers
- 384 people
- Sponsor
- Alcon Research
Eye Diseases, Postcataract Aphakia
Investigation of the Safety and Effectiveness of a Trifocal IOL
This study is a prospective, multicenter, randomized, double masked confirmatory trial comparing an investigational trifocal intraocular lens (IOL) and a commercially available monofocal IOL.
- Conditions
- Eye Diseases, Postcataract Aphakia, Cataract, Lens Opacities
- Trial name
- NCT04176965
- Testing
- FINEVISION HP IOL, Alcon AcrySof SN60AT
- Where
- 20 sites in United States
- Volunteers
- 539 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Visual Outcomes After Implantation of a New Multifocal Intraocular Lens
This prospective nonrandomized study comprised patients with cataract, corneal astigmatism, and motivation for spectacle independence. In all cases, a Rayner M-flex® T toric Intraocular Lens will be implanted in the capsular bag.
- Trial name
- NCT01505816
- Testing
- Multifocal Intraocular Lens (RAYNER M-FLEX T TORIC IOL)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Oftalmologico de Brasilia
Cataract
Pseudophakic Eyes With Presbyopia-correcting IOLs: OCT Biometry and Pyramid Aberrometry
To correlate ocular morphology from anterior segment OCT and pyramid wavefront sensing in order to comprehensively analyze pseudophakic in vivo image quality of presbyopia-correcting IOLs in cataract patients.
- Trial name
- NCT07436247
- Testing
- Osiris-T Pyramid Wavefront Sensor - (CSO, Italy)
- Where
- 2 sites in Austria
- Volunteers
- 80 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Cataract
IOL Power Calculation Using Dual Schiempflug Analyzer
This study evaluates the various ocular parameters which are necessary for ocular biometry and the calculated IOL powers using both dual Schiempflug analyzer and optical low-coherence refelctometry.
- Trial name
- NCT02362334
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Cataract
Tilt Prediction of Clareon Intraocular Lens
Misalignment of intraocular lenses can cause severe loss of visual quality. Different types of misalignments are known. Tilt, one type of intraocular lens misalignment is thought to play a negative role for the optical…
- Trial name
- NCT06595693
- Where
- Austria
- Volunteers
- 52 people
- Sponsor
- Johannes Kepler University of Linz
Cataract, Signs and Symptoms
Spherical Aberration and Contrast Sensitivity in IOLs
Purpose: To determine whether implantation of an intraocular lens (IOL) with a modified anterior aspheric surface results in reduced spherical aberration and improved contrast sensitivity after cataract surgery.
- Conditions
- Cataract, Signs and Symptoms, Pseudophakia, Lens Diseases
- Trial name
- IOLs (NCT00576485)
- Testing
- Cataract surgery and intraocular lens implantation
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Cataract
Visual Outcomes After Cataract Surgery: Multifocal AcrySof® IQ ReSTOR® Intraocular Lenses Versus Monofocal Intraocular Lenses
The purpose of this study is to assess and compare visual outcomes of the AcrySof® IQ ReSTOR® +3.0 D intraocular lens (IOL) to a commercially available monofocal IOL in cataract patients.
- Trial name
- NCT01290068
- Testing
- AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL, AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL, Monofocal IOL
- Volunteers
- 208 people
- Sponsor
- Alcon Research
Cataract, Pseudophakia
Wavefront Analisys and Contrast Sensitivity of Spherical and Aspherical Intraocular Lenses
Purpose:To compare visual performance, total and high order wavefront aberrations (coma, spherical aberration and other terms) and contrast sensitivity in eyes implanted with one monofocal aspheric intraocular lens (IOL) and two…
- Trial name
- NCT00347243
- Testing
- phacoemulsification (cataract surgery)
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Presbyopia, IOL, Cataract
Evaluation of the Visual Acuity Curves of an Enhanced Monofocal Intraocular Lens
The primary objective of this study is to evaluate postoperative visual acuity curves in pseudophakic patients following unilateral or bilateral implantation of the enhanced monofocal TECNIS Eyhance IOL, using the DDARTVC.
- Trial name
- IOL-VAC (NCT07439835)
- Testing
- Phacoemulsification with enhanced monofocal IOLs
- Where
- Greece
- Volunteers
- 62 people
- Sponsor
- Democritus University of Thrace
Astigmatism
Visual Performance With Clareon® Vivity® Intraocular Lenses (IOLs)
The purpose of this study is to generate clinical data to quantify the impact of residual astigmatism on the overall visual performance during distance, intermediate, and near viewing in patients implanted with Clareon Vivity…
- Trial name
- NCT06784063
- Testing
- Clareon Vivity Extended Vision IOL
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Alcon Research
Rhegmatogenous Retinal Detachment, Hypotony Ocular
Ocular Hypotony and Refractive Predictability in RRD Surgery
This study evaluates how preoperative ocular hypotony (Goldmann IOP ≤ 7 mmHg) affects refractive predictability, axial length measurements, and visual outcomes in patients undergoing combined phacovitrectomy with silicone oil for…
- Trial name
- HYP-RRD (NCT07283614)
- Testing
- Combined Phacovitrectomy with Intraocular Lens Implantation and Silicone Oil Tamponade, Silicone Oil Removal
- Where
- Kazakhstan
- Volunteers
- 45 people
- Sponsor
- Kazakh Eye Research Institute
Cataract
Clinical Evaluation of a New Aspheric Intraocular Lens.
This study evaluates the visual performance and occurrence of posterior capsular opacification after implantation of a new aspherical intraocular lens compared with a control spherical lens of otherwise identical design.
- Trial name
- NCT00786565
- Testing
- Advanced Akreos Adapt in one operated eye., Akreos Adapt in fellow operated eye.
- Volunteers
- 75 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Corneal Astigmatism
Post-market Study to Obtain Surgeon Feedback on Clinical Outcome in Eyes Implanted With TECNIS Toric II IOL
This is a multicenter, prospective, single-arm, open-label, clinical study of the commercially available TECNIS Toric II, Model ZCU IOL.
- Trial name
- NCT04210232
- Testing
- TECNIS® TORIC II Intraocular Lens (IOL)
- Where
- 12 sites in United States
- Volunteers
- 54 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract
Influence of DisCoVisc Ophthalmic Viscosurgical Device (OVD) on Intraoperative Aberrometry Readings
The purpose of the study is to develop a nomogram that correlates intraoperative, aphakic refraction measurements when the anterior chamber is pressurized with either balanced salt solution (BSS) or DisCoVisc; and to understand…
- Trial name
- NCT03751033
- Testing
- BSS, DiscoVisc
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Clinical Research Consultants, Inc.
Cataracts, Visual Acuity Reduced Transiently
The Incidence of Glistenings in the 2017 Intraocular Lenses Made by Alcon and Abbott Medical Optics
The purpose of this study is to seek academic/non-industry research funding support to independently investigate the incidence and density of lens glistenings in cataract patients who are implanted with the latest generations of…
- Conditions
- Cataracts, Visual Acuity Reduced Transiently, Loss of Visual Contrast Sensitivity, Functional Visual Loss
- Trial name
- NCT03409185
- Testing
- Alcon 1 piece SA60AT lens, AMO 1-piece AABOO lens
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Toronto
Cataract
Visual Function After Implantation of Bilateral AcrySof® Toric Natural Intraocular Lens
The purpose of this study is to evaluate the effect that placement and power of the AcrySof Toric has on post-operative visual acuity and spectacle independence for distance vision.
- Trial name
- NCT00760487
- Testing
- AcrySof Toric IOL
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Alcon Research