Clinical trials: Intraocular Lens Implant
Cataract, Presbyopia
A Clinical Evaluation of the LensGen Intraocular Lens
A multi-center, open-label, non-comparative clinical trial to assess the safety and efficacy of the LensGen IOL (Juvene IOL) for the treatment of aphakia and presbyopia after removal of the natural crystalline lens due to…
- Trial name
- Grail (NCT05364658)
- Testing
- Juvene IOL
- Where
- 2 sites in Mexico
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- LensGen, Inc.
Presbyopia, Ametropia
Clinical Trial With Artiflex Presbyopic (Artiplus)
The purpose of this clinical trial is to evaluate the effectiveness and safety of the multifocal Artiflex Presbyopic (Artiplus) intraocular lens.
- Conditions
- Presbyopia, Ametropia, Refractive Errors, Myopia
- Trial name
- NCT04632784
- Testing
- Artiflex Presbyopic (Artiplus) implantation
- Where
- 7 sites in South Korea, Spain
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Ophtec BV
Cataract
Visual Outcomes of Tecnis Symfony Opti-Blue EDOF Intraocular Lens (IOL)
Tecnis Symfony Optiblue EDOF IOL is the latest version of Tecnis Symfony IOL with a violet light filter (VLF), which blocks short-wavelength light and improves the quality of vision while minimizing visual disturbances.
- Trial name
- NCT06500416
- Testing
- Tecnis Symfony OptiBlue/ Tecnis Symfony OptiBlue toric IOL
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Coastal Eye Surgeons PLLC
Cataracts
A Comparative Pilot Study Of High-Order Aberrations With Aspheric IOL Models SN60WF and ZCB00
The purpose of this study was to prospectively compare high-order aberrations between eyes implanted with the AcrySof® Natural IQ (SN60WF) intraocular lens (IOL) versus those implanted with the Tecnis ZCB00 IOL.
- Trial name
- NCT01105585
- Testing
- Tecnis 1-piece Aspheric Acrylic (ZCB00) IOL, AcrySof Natural IQ (SN60WF) IOL
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Alcon Research
Age-Related Macular Degeneration, Lens, Intraocular
Implantation of SML in Patients With Dry Age-related Macular Degeneration and Myopic Maculopathy
Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss in developed countries among people over 50 years of age. Myopic maculopathy is also an important cause of irreversible vision loss.
- Conditions
- Age-Related Macular Degeneration, Lens, Intraocular, Myopic Maculopathy
- Trial name
- NCT03882606
- Testing
- Scharioth Macula Lens (SML, Medicontur)
- Where
- Spain
- Volunteers
- 3 people
- Sponsor
- Consorci Sanitari de Terrassa
Cataract Bilateral, Astigmatism Bilateral
Vision and Balance Changes After Bilateral Implantation of Toric IOLs
Cataracts are the major cause of blindness in the world. Cataract surgery, being the most performed surgery in the world today, provide correction by extracting the natural lens from its capsular bag and replaced by an artificial…
- Trial name
- NCT05629078
- Testing
- Toric intraocular lens Zeiss AT TORBI
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- University of Plymouth
Age Related Cataracts
Intraindividual Comparison of EMO IOLs
The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery.
- Trial name
- EMO (NCT05822089)
- Testing
- phacoemulsification and intraocular lens implantation
- Where
- Austria
- Volunteers
- 461 people
- Sponsor
- Medical University of Vienna
Glistenings
Evaluation of Glistenings in Intraocular Lenses Implanted in Normal Patients Following Routine Cataract Extraction.
Evaluation of glistenings in intraocular lenses implanted in normal patients following routine cataract surgery. The lenses used will be Model X-60 made by the AVS company Vs AcrySof MA50BM made by the Alcon company.
- Trial name
- AVS Vs MA50BM (NCT01131481)
- Testing
- Intraocular lens
- Where
- United States
- Sponsor
- Fry Eye Associates and Fry Eye Surgery Center
Cataracts
PROOF-OF-CONCEPT STUDY FOR NEW INTRAOCULAR LENS, MODEL C0002
Prospective, two-arm, randomized, bilateral, subject/evaluator-masked clinical study to evaluate the distance visual acuity, peripheral refractive error and functional vision of the EPV IOL compared to a standard monofocal…
- Trial name
- NCT05531292
- Testing
- Model C0002, Model ZCB00/DCB00
- Where
- 2 sites in France
- Volunteers
- 106 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract
Clinical Outcomes With Bilateral Implantation of Odyssey IOLs
This study is a single center, ambispective study of visual outcomes after successful bilateral cataract surgery. Subjects will be assessed at least 3 months postoperatively at a single visit.
- Trial name
- NCT06550375
- Testing
- TECNIS Odyssey IOL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mann Eye Institute
Glaucoma, Ocular Hypertension
Safety and Efficacy of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract Surgery
The goal of this clinical trial is to test a new method to deliver an approved medicine called Timolol in the eye of participants with glaucoma or ocular hypertension and requiring cataract surgery.
- Trial name
- NCT07036510
- Testing
- TimoD implant, Injector system, Timolol eye drops 0.5%
- Where
- Panama
- Volunteers
- 42 people
- Sponsor
- EyeD Pharma
Cataract
PureSee/Odyssey Mix-and-Match IOL
Observational, prospective, bilateral, single-arm investigator-initiated study. Single cohort at one site: TECNIS PureSee intraocular lens in the dominant eye and TECNIS Odyssey intraocular lens in the non-dominant eye.
- Trial name
- NCT07898917
- Testing
- Mix-and-match PureSee/Odyssey cohort
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Gainesville Eye Associates
Aphakia
Bicentric Clinical Investigation to Assess Safety and Performance of LuxBoost IOL
The study purpose is to demonstrate safety and performance of bilateral implantation of LuxBoost intraocular lenses compared with the LuxGood Monofocal lens.
- Trial name
- LuxBoost (NCT06258707)
- Testing
- LuxBoost IOL, LuxGood IOL
- Where
- 2 sites in France
- Volunteers
- 58 people
- Sponsor
- Cutting Edge SAS
Aphakia, Cataract
A Clinical Study to Evaluate The Safety and Effectiveness of The RxSight Light Adjustable Lens (LAL) In Subjects Desiring an Extended Depth of Focus
The primary objective of this study is to evaluate, for the visual correction of aphakia and presbyopia, the safety and effectiveness of the RxSight Light Adjustable Lens (LAL) to provide an extended depth of focus (improve…
- Conditions
- Aphakia, Cataract, Presbyopia
- Trial name
- NCT04177771
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD) - Pre-COVID Population, SofPort LI61AO IOL, Tecnis ZCB00 or ZTC150 IOL
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- RxSight, Inc.
Light Adjustable Lens, Objective Depth of Focus
Objective Depth-of-Focus Changes During Light Adjustable Lens UV Adjustments
This observational pilot study will examine how a person's vision changes during the routine adjustment and finalization of a Light Adjustable Lens (LAL) after surgery.
- Trial name
- NCT07868003
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Clarity Eye Institute
Cataracts
Clinical Investigation of AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0]
The purpose of this study is to compare the safety and efficacy of an investigational multifocal intraocular lens (IOL) to an FDA-approved monofocal IOL.
- Trial name
- NCT01510717
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0], AcrySof® IQ Monofocal IOL Model SN60WF
- Volunteers
- 409 people
- Sponsor
- Alcon Research
Cataract
Night Driving Pilot
Pilot study to evaluate usability of Mesotest II for assessment of night driving capacity of pseudo-phakic patients implanted with aspheric monofocal posterior chamber IOL *AT.Smart 46LC.
- Trial name
- NCT00876278
- Testing
- *AT.Smart 46LC
- Where
- Germany
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Visual Performance With a Trifocal Intraocular Lens
The purpose of this study is to evaluate the visual performance of a trifocal intraocular lens at distance, near and intermediate viewing, by way of visual acuity measurement, contrast sensitivity.
- Trial name
- NCT01605058
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BMI Southend Hospital
Cataracts
A Real-World Study for the TECNIS Synergy™ Intraocular Lens
This is a prospective and retrospective, single-center, single-arm, open-label clinical study of the TECNIS Synergy™ IOL. The study will enroll up to 100 subjects from a single site in China.
- Trial name
- NCT05090826
- Testing
- Model ZFR00V
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract, Lens Opacities
Clinical Study to Investigate Visual Performance of a Hydrophobic Monofocal IOL After Bilateral Implantation
Prospective, non-randomised, open, controlled, single-center post-market clinical follow study about Micropure 1.2.3 IOL.
- Trial name
- PHY1801 (NCT03423524)
- Testing
- Micropure 1.2.3.
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.