Clinical trials: Intraocular Lens Implant
Corneal Endothelial Cell Loss, Secondary Intraocular Lens
Anterior Chamber Versus Scleral Fixated Intraocular Lens: Long-term Vision and Safety Outcomes
This is a prospective comparative non-randomized cohort study to understand the long-term vision outcomes, safety, and stability of anterior chamber intraocular lenses (AC IOLs) vs. scleral-fixated intraocular lenses (SF IOLs).
- Trial name
- NCT04072978
- Testing
- Intraocular lens implantation
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Cataract
A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects
Prospective, randomized, multicenter, multi-arm, subject and vision-assessor-masked, two stage study with Stage 1 as a three-arm initial enrollment period, followed by Stage 2 as a head-to-head study refined based on the Stage 1…
- Trial name
- NCT06922084
- Testing
- Clareon PanOptix, Clareon PanOptix PRO, Mix-and-Match PanOptix/Vivity
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Berkeley Eye Center
Cataract
A Prospective, Single-Arm Clinical Evaluation of Visual, Refractive, and Patient-Reported Outcomes Following Bilateral Implantation of the TECNIS PureSee™ Extended Depth of Focus Intraocular Lens
Assess the visual, refractive, and patient-reported outcomes - including spectacle independence - of bilateral cataract surgery with implantation of the TECNIS PureSee extended depth of focus (EDOF) IOL in subjects with visually…
- Trial name
- NCT07790887
- Testing
- PureSee IOL
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Vance Thompson Vision
Pseudophakia
Corrected VA With Long-Term Follow-Up After AcrySof® Intraocular Lens (IOL) Implantation
The purpose of this study is to compare the long-term visual acuity (VA) with an acrylic IOL to a silicone or polymethylmethacrylate (PMMA) IOL in cataract patients. This study will take place in Japan.
- Trial name
- NCT02450799
- Testing
- Acrylic IOL, Silicone IOL, PMMA IOL
- Volunteers
- 104 people
- Sponsor
- Alcon, a Novartis Company
Presbyopia
Visual Outcomes After Presbyopic Lens Exchange
Evaluation of mean preoperative and postoperative Corrected distance visual acuity (CDVA) after Refractive Lens Exchange in presbyopic patients
- Trial name
- RELAX (NCT03790592)
- Testing
- trifocal IOL
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Intraocular Lens Implantation
The Femtosecond Laser in Residency Training (FLIRT) Pilot Study
This pilot study aims to primarily assess the rate of complication of anterior vitrectomy for patients undergoing femtosecond laser-assisted (FLA) cataract extraction and intraocular lens placement (CEIOL) compared to manual…
- Trial name
- FLIRT (NCT03115216)
- Testing
- FLA-CEIOL, CEIOL
- Sponsor
- University of Southern California
Cataract
Comparative Study of 2 Multifocal Intraocular Lenses in Heidelberg
The goal of this clinical trial is to compare the performance of 2 intraocular lenses (IOLs): ARTIS SYMBIOSE (study lenses) vs PANOPTIX (comparator) through binocular Distance Corrected Intermediate Visual Acuity (DCIVA) assessed…
- Trial name
- C2H (NCT06327347)
- Testing
- intraocular lens implantation in cataract surgery
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Cristalens Industrie
Posterior Chamber Phakic Intraocular Lens, Vault
Study on the Diagnostic Efficacy of ICL Selection and Prediction Depth Model Based on Eye Images
To evaluate the diagnostic efficacy of deep learning network model in implantable collamer lens selection and prediction in a multicenter cross-sectional study
- Conditions
- Posterior Chamber Phakic Intraocular Lens, Vault, Deep Neural Network, Myopia
- Trial name
- NCT06669728
- Testing
- AI diagnostic algorithm
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Cataract, Visual Quality
Visual Outcomes of Functional Intraocular Lenses in Cataracts
This is a prospective, multi-center, randomized comparative study. The purpose of the study is to evaluate and compare the objective and subjective visual outcomes of different types of functional intraocular lenses (IOLs) in…
- Trial name
- NCT06092164
- Volunteers
- 20,000 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Presbyopia
Mix and Match Study of Two Multifocal Intraocular Lens With Different Add Power
To assess postsurgical visual acuity (distant, intermediate, near), refractive errors, contrast sensitivity, visual function and patient satisfaction after implantation of multifocal IOLs of different add power contralaterally.
- Trial name
- NCT02556944
- Testing
- Phacoemulsification with multifocal intraocular lens
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- tae-young chung
Congenital Cataract
Secondary Intraocular Lens Implantation in Pediatric Patients
This prospective, non-randomized controlled study aiming at comparing the prognosis of minimal invasive lens surgery and traditional cataract surgery for treating congenital cataracts after the patient receives secondary…
- Trial name
- NCT03240796
- Testing
- minimal invasive surgery and secondary IOL implantation, traditional cataract surgery and secondary IOL implantation
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sun Yat-sen University
Cataract, Lens Opacity
Comparison of Visual Outcomes After Implantation of the POD AY GF F (PhysIOL) and the POD AY 26P F (PhysIOL)
The study is a prospective randomised controlled study. The patients get monolateral IOL implantation of POD F GF and POD F in the contralateral eye. Both IOLs are trifocal IOLs consisting of the same optical design.
- Trial name
- NCT02981186
- Testing
- IOL implantation experimental, IOL implantation comparator
- Where
- Hungary
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Presbyopia Correction, Astigmatism
A Planned Study at Multiple Sites is Being Done to Compare the Results of Two Types of Trifocal Toric Intraocular Lenses Used in Cataract Surgery
To evaluate the clinical outcomes and patient satisfaction of two commercially available trifocal toric intraocular lenses Primary Objective: To compare the distance-corrected intermediate visual acuity between the two trifocal…
- Conditions
- Presbyopia Correction, Astigmatism, Cataract
- Trial name
- NCT07232615
- Testing
- Optiflex TRIO Intraocular Lens, AcrySof® IQ PanOptix®
- Where
- 6 sites in Germany, India and 1 more
- Volunteers
- 138 people
- Sponsor
- Biotech Healthcare Holding Gmbh
Astigmatism, High Myopia
Comparison Between TICL and ICL+AK for High Myopic Astigmatism
To compare the outcomes of a toric Implantable Collamer Lens (ICL) and a spherical Implantable Collamer Lens combined with astigmatic keratotomy (AK) in the correction of high myopic astigmatism.
- Trial name
- NCT03202485
- Testing
- Toric Implantable Collamer Lens, ICL + Astigmatic keratotomy
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation
Dextenza Within Upper Lid Canaliculus Compared With Lower Lid Canaliculus Following Bilateral Cataract Extraction Surgery With PCIOL.
Assessing DEXTENZA efficacy when placed within the upper eyelid canaliculus as opposed to the lower eyelid canaliculus.
- Trial name
- NCT04592081
- Testing
- Dextenza 0.4Mg Ophthalmic Insert
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kerry Assil, MD
Cataracts
AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan
The purpose of this study is to evaluate safety and effectiveness of AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0] in Japanese cataract patients.
- Trial name
- NCT01605877
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]
- Where
- 2 sites in Japan
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Cataract Senile
Precisight® Intraocular Lens Implantation for Cataract Treatment
The purpose of this study is to determine the refractive outcomes and optimize the clinical features of a new intraocular lens intended to treat the senile cataract.
- Trial name
- PEACE (NCT02970487)
- Testing
- Intraocular implant of the Precisight
- Where
- Philippines
- Volunteers
- 96 people
- Sponsor
- InfiniteVision Optics
Cataract
Clinical Evaluation of a 1-Piece Intraocular Lens
The aims of this study are to: Demonstrate a reduction in postoperative cylinder compared to results from the control lens Demonstrate better uncorrected distance visual acuity compared to the control lens
- Trial name
- NCT01098812
- Testing
- Tecnis ZCB00 IOL (control), Toric Intraocular lens
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Posterior Capsule Opacification
Posterior Capsule Opacification Following Cataract Surgery With Implantation of the MICS IOL L313
This study collects intra- and postoperative data from the patients´charts retrospectively and evaluates retro- and prospectively the rate of posterior capsule opacification (PCO) following implantation of the intraocular lens L…
- Trial name
- NCT03184428
- Testing
- Postoperative observation and survey
- Where
- Germany
- Volunteers
- 3,785 people
- Sponsor
- Dietrich-Bonhoeffer-Klinikum
Pterygium, Cataract
Effect of Pterygium Excision on Intraocular Lens Power Calculation for Subsequent Cataract Operation
Pterygium is known to induce with-the-rule astigmatism. Excision of pterygium will steepen the cornea and reduce corneal astigmatism.
- Conditions
- Pterygium, Cataract, Astigmatism
- Trial name
- NCT00563667
- Testing
- pterygium excision
- Where
- 3 sites in China
- Volunteers
- 40 people
- Sponsor
- Hospital Authority, Hong Kong