Clinical trials: Intraocular Lens Implant
Cataract
VisiOn Restoration With FluidVisION Accommodating Intraocular Lens (AIOL)
The objective of this study is to obtain an initial assessment of the safety and performance of an investigational AIOL in patients undergoing cataract extraction and IOL implantation.
- Trial name
- ORION (NCT03925545)
- Testing
- FluidVision AIOL, AcrySof IQ monofocal IOL, Cataract surgery
- Volunteers
- 85 people
- Sponsor
- PowerVision
Complications
Characteristics and Risk Ratios of Late Intraocular Lens (IOL) Complication
Late in-the-bag intraocular lens (IOL) dislocation occurs up to 30 years after cataract surgery and the prevalence ranges from 0.1% to 3.0%.
- Trial name
- NCT02747667
- Volunteers
- 10,125 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
To Collect Information About Visual Outcomes and Participant Satisfaction
Prospective Evaluation of Visual Outcomes With Tecnis One-Piece Multifocal Intraocular Lenses Compared With Patients Previously Implanted With Crystalens Aspheric Optic (AO)
The study is being conducted to collect information about visual outcomes and participant satisfaction with the Tecnis One-Piece Multifocal (MF) Intraocular Lenses (IOLs) compared with participants previously implanted with…
- Trial name
- NCT01191229
- Testing
- Tecnis one-piece MF IOL, Crystalens AO
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Posterior Capsule Opacification After Phacoemulsification and IOL Implantation
Long-term Evaluation of Single-piece ACrysof IOL Implantation on Development of Posterior Capsule Opacification
Although contemporary cataract surgery has made tremendous strides in technological advancement, posterior capsular opacification (PCO) is still the most frequent long-term complication leading to decreased visual functions and…
- Trial name
- NCT01820065
- Testing
- Cataract surgery with IOL implantation
- Where
- India
- Volunteers
- 390 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract Congenital
Multifocal vs Monofocal IOL in Congenital Cataract Surgery
The aim of this study is to evaluate long-term outcome after congenital cataract surgery comparing results achieved with multifocal and monofocal IOLs.
- Trial name
- NCT04872829
- Testing
- cataract surgery
- Volunteers
- 43 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Cataract
Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
- Trial name
- NCT00703781
- Testing
- bromfenac ophthalmic solution
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Aphakia
A Multi Focal Visual Outcome Study Using Different Near Additions
A multi-centre non-randomized clinical investigation to assess multifocal visual outcomes using different near additions, for the treatment of aphakia after cataract removal.
- Trial name
- NCT00960700
- Testing
- Visual Acuity, Contrast sensitivity, Reading Speed
- Where
- 2 sites in Germany, Lithuania
- Volunteers
- 52 people
- Sponsor
- Rayner Intraocular Lenses Limited
Cataract
Yellow Versus White Study
Blue-light-filtering IOLs are implanted increasingly often in cataract surgery. Several studies examined the effect of blue-light-filters on contrast and colour vision. However, the study outcomes were varying.
- Trial name
- YeWhi (NCT00612781)
- Testing
- cataract surgery (Hoya AF-1 [UY] YA-60BB), cataract surgery (Hoya AF-1 [UV] VA-60BB lens)
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Hospital Hietzing
Dysphotopsia, Posterior Capsule Opacification
Clinical Evaluation of Low Contrast Visual Performance and Low Light Phenomena in Patients With Various Intraocular Lens Implants
The goal of this clinical investigation is to evaluate visual acuity and contrast sensitivity in low lighting conditions using several different testing devices, and measure nighttime side effects of intraocular lens (IOL)…
- Conditions
- Dysphotopsia, Posterior Capsule Opacification, Visual Acuity, Visual Function
- Trial name
- NCT07213167
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Dr. Daniel H. Chang, MD
IOL, Cataract
Visual Performance of Multifocal Intraocular Lenses
To evaluate the clinical outcomes with an extended range of vision (ERV) IOL based on achromatic diffractive technology.
- Trial name
- NCT04913792
- Testing
- ZXR00
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Wenzhou Medical University
Cataract
Clinical Investigation of a New Intraocular Lens
The purpose of this clinical trial is to evaluate the safety and effectiveness of the TECNIS Symfony Extended Range of Vision IOL.
- Trial name
- NCT02203721
- Testing
- TECNIS Symfony Extended Range of Vision IOL, Model ZXR00, TECNIS Monofocal IOL, Model ZCB00
- Where
- 15 sites in United States
- Volunteers
- 324 people
- Sponsor
- Abbott Medical Optics
Cataract, Pseudophakia
Retrospective, Non-interventional Clinical Investigation of the Safety and Performance of 640AD Monofocal Intraocular Lens
Medicontur hydrophilic posterior chamber monofocal intraocular lens (IOL) is indicated to improve vision at far distance in adults with cataract and/or ametropia (hyperopia, myopia), secondarily to removal of the crystalline…
- Trial name
- NCT06578910
- Testing
- Standard of care, Patient satisfaction questionnare
- Where
- Hungary
- Volunteers
- 80 people
- Sponsor
- Medicontur Medical Engineering Ltd
Primary Angle Closure
Primary Angle Closure Glaucoma and Aqueous Dynamics
The aim of the study is to determine which is the best treatment for people with cataract and primary angle closure (PAC).In PAC, apposition of the iris tissue to the drainage channels (Trabecular Meshwork-TM) of the eye results…
- Trial name
- NCT00719290
- Testing
- Phacoemulsification (Acrylic Foldable Intraocular Lens (Acrysoft)), (Healon5), Phacoemulsification and goniosynechialysis (Acrylic Foldable Intraocular Lens (Acrysoft)), (Healon5)
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cataract
Presbyopia-Correcting Intraocular Lenses (IOLs)
The purpose of this study is to prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with Presbyopia-Correcting Intraocular Lenses (IOLs).
- Trial name
- NCT00963560
- Testing
- ReSTOR +3, Crystalens HD, Crystalens AO
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Alcon Research
Aphakia, Cataract
One-Piece Hydrophobic Acrylic Intraocular Lens in Subjects Undergoing Cataract Extraction
The objective of this study is to evaluate the safety and effectiveness of the enVista® One-Piece Hydrophobic Acrylic intraocular lens (IOL), following primary implantation for the visual correction of aphakia in adults 18 years…
- Trial name
- NCT01230060
- Testing
- enVista
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Bausch & Lomb Incorporated
Posterior Capsule Opacification, Cataract
Posterior Capsule Opacification and Frequency of Nd:YAG Treatment and of Two IOLs: Hoya iMics Y-60H vs. Bausch&Lomb MI60 (MIMI)
Age-related cataract is the main cause of impaired vision in the elderly population worldwide. The only treatment that can restore functional visual ability is cataract surgery where the opacified crystalline lens is removed by…
- Trial name
- NCT01786356
- Testing
- HOYA iMics Y-60H, B&L MI60
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Cataract
Evaluation of Binocular Visual Acuity and Refractive Stability in the Alcon Clareon Intraocular Lens
The objective is to evaluate refractive stability (spherical equivalent change ≤ 0.50D from 1-month to 3-months).
- Trial name
- NCT04936256
- Testing
- Clareon
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Gainesville Eye Associates
Cataract
Odyssey Evaluation in Post LASIK Patients
This prospective study evaluates the visual and refractive outcomes of the TECNIS Odyssey intraocular lens (IOL) implanted in patients with a history of myopic LASIK.
- Trial name
- NCT07260695
- Testing
- Odyssey intraocular lens
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Center For Sight
Cataract
Visual Function After Implantation of Bilateral AcrySoft ReSTOR Aspheric IOL
This study will involve up to 20 bilateral patients per surgeon. Patients will be assessed pre-operatively, and at subsequent visits (following the implantation of the intraocular lens in the second eye) at 1 week, 1 month, 3…
- Trial name
- NCT00934622
- Testing
- AcrySof® ReSTOR® Aspheric IOL
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Alcon Research
Cataract Congenital, Astigmatism
Toric Intraocular Lens Implantation in Pediatric Cataract
To evaluate the visual and refractive outcomes after an intraocular lens (IOL) implantation in pediatric eyes with cataract and preexisting corneal astigmatism
- Conditions
- Cataract Congenital, Astigmatism, IOL
- Trial name
- TILIPC (NCT06294795)
- Testing
- congenital/pediatric cataract surgery, Non-Toric IOLs, Toric IOLs
- Where
- 2 sites in Kazakhstan
- Volunteers
- 40 people
- Sponsor
- Kazakh Eye Research Institute