Clinical trials: Intraocular Lens Implant
Bilateral Cataract, Astigmatism
Non-comparative Trial Following Participants Implanted Bilaterally With Mini WELL Toric Ready Intraocular Lens for 6 Months After the Second Eye Implant (FUSION)
This is a multicenter, non-comparative trial following participants implanted bilaterally with the Mini WELL Toric Ready intraocular lens (IOL) for 6 months after the second eye implant.
- Trial name
- FUSION (NCT03861351)
- Testing
- Mini WELL Toric Ready intraocular lens
- Where
- 4 sites in France, Germany and 1 more
- Volunteers
- 58 people
- Sponsor
- SIFI SpA
Posterior Synechiae of Iris
Mydriatic Drops After Combined Surgery
The study goal is to evaluate the influence of mydriatic drops on the development of posterior synechia after combined cataract and vitrectomy surgery.
- Trial name
- NCT05614622
- Testing
- Cyclopentolate Hydrochloride 1.0% eye drops
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Primary Open Angle Glaucoma (POAG), Cataract
Study of an Implantable Device for Lowering Intraocular Pressure in Glaucoma Patients Undergoing Cataract Surgery
The purpose of this study is to evaluate the safety and efficacy of the CyPass Implant for lowering intraocular pressure (IOP) in patients with glaucoma who undergo cataract surgery.
- Trial name
- COMPASS (NCT01085357)
- Testing
- Cataract Surgery, CyPass Micro-Stent
- Volunteers
- 897 people
- Sponsor
- Transcend Medical, Inc.
Glaucoma, Cataract
Vivity Outcomes in Patients With Early Stage Glaucoma
The goal of the study is to determine the visual outcomes in patients with mild, pre-perimetric glaucoma who undergo cataract surgery with implantation of the Alcon Vivity Extended Range Intraocular Lens (IOL).
- Conditions
- Glaucoma, Cataract, Presbyopia
- Trial name
- VIVA (NCT04670575)
- Testing
- Cataract Surgery with Implantation of Vivity Extended Range of Vision IOL
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Vance Thompson Vision
Cataract
Three Intraocular Lenses Designed to Improve Distance, Intermediate and Near Vision Following Lens Extraction
The objective of this study is to compare the contrast sensitivity, high and low contrast visual acuity (VA), glare meter outcomes, and subject satisfaction with three different FDA-approved intraocular lenses (IOLs) designed to…
- Trial name
- NCT01225952
- Testing
- Crystalens AO, ReSTOR 3.0, AMO Tecnis Multifocal
- Where
- Philippines
- Volunteers
- 93 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Evaluation of the Safety and Effectiveness of the Akreos MI Five-0 Intraocular Lens.
The objective of this 12-month clinical investigation is to evaluate the safety and effectiveness of the Bausch \& Lomb Akreos MI Five-O intraocular lens (IOL).
- Trial name
- NCT00804726
- Testing
- Akreos MI Five-O
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Visual Outcome and Visual Quality After Bilateral Implantation of the AcrySof® IQ IOL Compared to MI60® and Tecnis® IOL
The objective of the study is to compare the visual outcomes of three aspheric monofocal intraocular lenses after cataract surgery - ACRYSOF® IQ, Tecnis® and Akreos® MI60.
- Trial name
- NCT00760058
- Testing
- AcrySof® IQ IOL, Tecnis® Aspheric intraocular lens, Akreos® MI60 intraocular lens
- Where
- United States
- Sponsor
- Alcon Research
Dry Eye Disease (DED), Cataract
Impact of DED on the Accuracy of Preoperative Keratometry Values in the Calculation of IOL Power for Cataract Surgery.
This study looks at how dry eye disease can affect important eye measurements needed before cataract surgery. These measurements guide us in choosing the right artificial lens to implant, which is essential for achieving clear…
- Trial name
- NCT06989827
- Testing
- Preservative free artificial tear
- Where
- Croatia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Sestre Milosrdnice
Age-related Cataract
Evaluation of Capsular Bag Shape Changes After Plate-haptic Intraocular Lens Implantation by SS-OCT
Evaluation of capsular bag shape changes after plate-haptic intraocular lens implantation by SS-OCT.
- Trial name
- NCT05148741
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenzhou Medical University
Cataract
AI-Driven IOL Prediction Using SS-OCT Biometry
This prospective, multicenter, non-interventional observational study aims to evaluate the agreement between a novel swept-source optical coherence tomography (SS-OCT) biometer and the IOLMaster 700 for ocular biometric…
- Trial name
- NCT07733154
- Testing
- IOLMaster 700, Novel SS-OCT Biometer
- Where
- 3 sites in Australia, China and 1 more
- Volunteers
- 2,500 people
- Sponsor
- The Hong Kong Polytechnic University
Cataract, Aphakia
Evaluation of the Safety & Effectiveness of the Bausch & Lomb AKREOS® TL Intraocular Lens
This study is to evaluate the safety and effectiveness of the Bausch \& Lomb Akreos TL (thin lens) intraocular lens (IOL) following implantation in adults requiring cataract surgery.
- Trial name
- NCT00838045
- Testing
- The Bausch & Lomb Akreos TL IOL (MI60) posterior chamber IOL
- Where
- Germany
- Volunteers
- 125 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Hyperopia
A Clinical Evaluation of a Phakic Intraocular Lens
The objective of this study is to evaluate the clinical performance of the STAAR EVO+ Visian™ Implantable Collamer® Lens with Aspheric (EDOF) Optic as refractive elements to correct or reduce myopia or hyperopia with presbyopia…
- Conditions
- Myopia, Hyperopia, Astigmatism, Presbyopia
- Trial name
- NCT07291739
- Testing
- Implantable Collamer Lens (ICL)
- Where
- Philippines
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Staar Surgical Company
Presbyopia
Luminous Efficiency Function V(λ)' of Patients That Underwent Pseudophakic Presbyopic Corrections
Primary objective of this study is to construct and validate a modified luminous efficiency function that addresses the distinct total eye light transmittance of patients that underwent bilateral pseudophakic presbyopic…
- Trial name
- NCT04263636
- Testing
- Phacoemulsification with bilateral trifocal diffractive IOLs
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Cataract
Trial Following Subjects Bilaterally Implanted With Mini Well Ready For 2 Years After the Second Eye Implant
The study objective is to evaluate the visual performance of MINI WELL Ready at 24 months following the second eye implant. The objectives of safety are to evaluate the rate of Secondary Surgical Interventions related to the…
- Trial name
- NCT04801992
- Testing
- MINI WELL Ready (SIFI SpA, Italy)
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- SIFI SpA
Congenital Cataract
Infant Aphakia Treatment Study (IATS)
The primary purpose is to determine whether infants with a unilateral congenital cataract are more likely to develop better vision following cataract extraction surgery if they undergo primary implantation of an intraocular lens…
- Trial name
- IATS (NCT00212134)
- Testing
- Contact lens correction of aphakia, Intraocular lens implantation
- Where
- 13 sites in United States
- Volunteers
- 114 people
- Sponsor
- Stanford University
Lens Implantation, Intraocular, Cataract
Evaluation of the Long-term Efficacy and Safety of Monofocal Plate Haptic Intraocular Lens
Our study aims to determine the efficacy and safety of the monofocal plate haptic intraocular lens to be implanted in patients planning for cataract surgery and to determine the complications that may develop due to the lens.
- Trial name
- NCT06238271
- Testing
- Acriva BB UDM 611
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Yuzuncu Yil University
Cataract Senile
Prospective Evaluation of an Hydrophilic Acrylic Intraocular Lens
Evaluation of the clinical safety and effectiveness of an hydrophilic acrylic intraocular lens
- Trial name
- UVEA 809 (NCT04907500)
- Testing
- Intraocular lens
- Where
- Romania
- Volunteers
- 387 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Comparison of Functional Vision Provided by AMO Tecnis Z9000 and Alcon SA60AT Acrysof
This study is to compare intraindividually the functional vision provided by two different posterior chamber intraocular lenses: AMO Tecnis Z9000 and Alcon SA60AT Acrysoft.
- Trial name
- NCT00459303
- Testing
- aspherical intraocular lens, spherical intraocular lens
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
High Myopia
Accuracy of Intraocular Lens Power in High Myopia
evaluation of the accuracy of iol power in high myopia using different biometry formula \& iol master
- Trial name
- NCT03394300
- Testing
- iol power calculation
- Volunteers
- 30 people
- Sponsor
- Assiut University
Cataract
A Clinical Study Comparing Postoperative Outcomes Between the TECNIS Intraocular Lens.
This is a prospective, multi-center, masked, three-arm, randomized clinical study of the TECNIS Eyhance Toric II IOL (test #1) and TECNIS Synergy Toric II (test #2) compared to the TECNIS Toric 1-Piece IOL (control).
- Trial name
- NCT05396599
- Testing
- Model DIU, Model DFW, Model ZCT
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.