Clinical trials: Intraocular Lens Implant
Cataract, Astigmatism
Rotational Stability of the Acrysof, Tecnis and Envista Intraocular Lenses
Brief Summary: Age-related cataract is the main cause of impaired vision in the elderly population worldwide. In the UK, more than half of people who are over 65 years old have some cataract development in one or both eyes.
- Trial name
- NCT04345380
- Testing
- Implantation of an Alcon Acrysof SN60WF intraocular lens, Implantation of an AMO Tecnis ZCB00 intraocular lens, Implantation of an Envista MX60 intraocular lens
- Where
- Austria
- Volunteers
- 199 people
- Sponsor
- Medical University of Vienna
Aphakia Cataract
Long-Term Clinical Outcomes Of Subjects Enrolled In The RxSight Light Adjustable Lens (LAL) And Light Delivery Device (LDD) New Enrollment Study
This is an observational, follow up study of subjects previously enrolled in the "RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) New Enrollment Study".
- Trial name
- NCT07347379
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- 6 sites in United States
- Volunteers
- 108 people
- Sponsor
- RxSight, Inc.
Pediatric Cataract
Outcome of Capsular After Pediatric Cataract Surgery With Primary Intraocular Lens Implantation
The aim of this study is to evaluate the outcome of capsular in children with cataract, and to explore potential preoperative structural clues for postoperative glaucoma.
- Trial name
- Capsular (NCT04357249)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Wenzhou Medical University
Cataract
Visual Performance of an Extended Depth of Focus IOL in an Emmetropic or Monovision Modality
Comparison of the visual performance of a refractive extended depth of focus intraocular lens in an emmetropic or monovision modality
- Trial name
- NCT06624826
- Testing
- Emmetropic modality, Monovision modality
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Cataract, Corneal Astigmatism
Clinical Investigation of the Safety and Effectiveness of an Investigational Model of the TECNIS® Intraocular Lens
This study will be a prospective, multicenter, bilateral, comparative, three-way masked (Sponsor, subject and evaluator), randomized clinical investigation conducted at up to 15 sites.
- Trial name
- BRAVO (NCT03949335)
- Testing
- IOL Model ZFR00V, IOL Model ZCB00
- Where
- 15 sites in United States
- Volunteers
- 272 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Intraocular Lens, Cataract
Comparison of a Novel Non-diffractive Extended Depth of Focus Intraocular Lens (IOL) and a Trifocal IOL
The purpose of this study is to compare visual performance and quality of life (QOL) following bilateral implantation of a novel non-diffractive extended depth-of-focus (EDOF) intraocular lens (IOL) (AcrySof® IQ Vivity, Alcon…
- Conditions
- Intraocular Lens, Cataract, Quality of Life
- Trial name
- NCT05262504
- Testing
- İntraocular lens implantation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Baskent University Ankara Hospital
Cataract
A-constant Optimization of a Toric Monofocal IOL
The study is a prospective series study to determine the IOL constant of a hydrophilic toric monofocal intra-ocular lens (IOL)
- Trial name
- NCT04944238
- Testing
- Ankoris
- Where
- Belgium
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Clinical Investigation of Omega Refractive Capsule, Model VI
The objective of this study is to evaluate the safety and effectiveness of the investigational Omega Refractive Capsule (model VI)
- Trial name
- ORCVI (NCT04574115)
- Testing
- Omega Refractive Capsule with an FDA approved Intraocular Lens, FDA approved Intraocular Lens
- Where
- Costa Rica
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Omega Ophthalmics
Congenital Cataract
Comparison of Minimal Invasive Lens Surgery and Traditional Cataract Surgery
Previously, we have developed a minimal invasive lens surgery in the purpose of reduce post-operative complications of congenital cataract.
- Trial name
- NCT03230799
- Testing
- minimal invasive lens surgery, traditional cataract surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Cataracts
Clinical Investigation of the TECNIS® Next-Generation Intraocular Lens, Model DEN00V
Prospective, multicenter, bilateral, masked (sponsor, subject and evaluator), randomized clinical trial to evaluate the safety and effectiveness of the TECNIS IOL, Model DEN00V in comparison to an aspheric monofocal IOL.
- Trial name
- NCT05574959
- Testing
- investigational IOL Model DEN00V, control IOL Model ZCB00/DCB00
- Where
- 10 sites in United States
- Volunteers
- 243 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Lens Opacities, Cataract
Clinical Outcomes of an New EDOF IOL (Isopure®)
Single-center, retrospective, open-label observational study aiming to evaluate visual outcomes and patient satisfaction after bilateral implantation of Isopure® EDOF-IOL with a mono-minovision target.
- Conditions
- Lens Opacities, Cataract, Pseudophakia
- Trial name
- NCT05704686
- Testing
- Isopure 1.2.3 intraocular EDOF lens implantation
- Where
- Switzerland
- Volunteers
- 62 people
- Sponsor
- Kristof Vandekerckhove, MD, MBA
Pediatric Cataract, Congenital Cataract
Toric Intraocular Lens Implantation for Pediatric Aphakia
Here, we conducted a nonrandomized clinical trial aims to evaluate and compare the prognosis of visual function in children of these two types of IOL implantation over a three-year postoperative period.
- Trial name
- NCT07088796
- Testing
- Toric IOL implantation, Non-toric IOL implantation
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Cataract
Optimizing the Assessment of Refractive Outcomes After Cataract Surgery
The purpose of this study is to evaluate current available assessments (automated vs. manual) with which manifest refraction data and biometric variables are obtained to understand if data from an automated refractor can be…
- Trial name
- NCT02842151
- Testing
- Manifest refraction, ACRYSOF® IQ Monofocal IOL Model SN60WF, Topcon® KR-1W Wave-Front Analyzer
- Volunteers
- 162 people
- Sponsor
- Alcon Research
Cataract
Low-add Multifocal vs. Monofocal IOLs
Compare low-add multifocal IOLs with monofocal IOLs to evaluate if patients in the low-add multifocal IOL group have better unaided distance visual acuity compared to the monofocal group.
- Trial name
- NCT03749161
- Testing
- Low-add multifocal IOL, Monofocal IOL
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Intraocular Lens Rotation, Capsular Tension Ring
Combined Capsular Tension Ring and IOL Implantation for Management of Cataracts
This study included cataract patients who underwent intraocular lens (IOL) implantation with or without capsular tension ring (CTR), which aimed to evaluate the contribution of the use of CTR in clinical visual outcomes and…
- Trial name
- NCT05530473
- Testing
- capsular tension ring
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Eye Disorders, Cataract Extraction
Effectiveness of a Large Language Model-Based Educational Tool on Intraocular Lens Options
Patients with cataracts disease need to choose what type of artificial lens will go into their eye prior to surgery date. Some lenses are standard and are usually covered by insurance.
- Conditions
- Eye Disorders, Cataract Extraction, Cataract and IOL Surgery, Cataract Surgery Experience
- Trial name
- NCT07317661
- Testing
- LLM-based Education
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Stanford University
Lens Implantation, Intraocular
Wavefront Analysis and Contrast Sensitivity After Cataract Surgery With Akreos Advanced Optics Intraocular Lens Implantation
Purpose: To determine whether implantation of an intraocular lens (IOL) with a modified anterior and posterior aspherical surface (Akreos AO, Bausch \& Lomb,Inc) results in reduced ocular aberrations (spherical aberration) and in…
- Trial name
- NCT00863759
- Testing
- implantation of intraocular lens (IOL)
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- University of Sao Paulo
Cataract Senile
Study on Visual Performance of a Monofocal Intraocular Lens
Retrospective/Prospective Study on Visual Performance of a Monofocal Intraocular Lens (IOL). The objective is to compare best corrected distance visual acuity (CDVA) between 1-3-month and 12- month follow-up.
- Trial name
- NCT04740788
- Testing
- Monofocal IOL
- Where
- Austria
- Volunteers
- 44 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
To Compare Early Rotation of Two Extended Depth of Focus Intraocular Lenses
To demonstrate that the Carl Zeiss Meditec (CZM) Extended depth of focus (EDOF) Intraocular lens (IOL) is superior to the competitor EDOF IOL with respect to Rotational Stability.
- Trial name
- VENUStoric (NCT03839420)
- Testing
- CZM IOL, Competitor IOL
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Performance of a Hydrophilic and a Hydrophobic Intraocular Lens of Similar Design
Comparison of the capsular bag performance of the RayOne Hydrophobic Aspheric with the RayOne Aspheric
- Trial name
- NCT03955796
- Testing
- Hydrophobic IOL, Non-hydrophobic IOL
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA