Clinical trials: Intraocular Lenses
Cataract
Evaluation of the BunnyLens TR Intraocular Lens
With age, a human crystalline lens opacifies (cataract) disabling the eye in generating a clear, well contrasted image. The only therapeutic solution to this problem is surgical replacement of the crystalline lens with an…
- Trial name
- NCT01659801
- Testing
- BunnyLens TR
- Volunteers
- 25 people
- Sponsor
- Hanita Lenses
Cataract, Lens Opacities
PMCF Retrospective Study Outcomes of a Premium Monofocal IOL
Multicentric, retro- / prospective, open-label, observational PMCF study to investigate visual performance, contrast sensitivity and patient satisfaction after mono- or bilateral implantation of Isopure 1.2.3.
- Trial name
- PHY2110 (NCT04874376)
- Testing
- IOL implantation experimental (Isopure 1.2.3.)
- Where
- 6 sites in Spain
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
A Intra-patient Comparison of Closed Loop and Plate Haptic Toric Intraocular Lenses
During cataract surgery an artificial lens is implanted in the eye. These artificial lenses are called intraocular lenses (IOLs) and there are many different types of IOL designs.
- Trial name
- NCT02264457
- Testing
- T-flex Aspheric Toric IOL, AT TORBI toric IOL
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Plymouth
Cataract, Lens Opacities
Clinical Outcomes of MICROPURE and PodEye Monofocal Intraocular Lenses
Prospective, non-randomised, open, controlled, single-center post-market clinical follow study about Micropure 1.2.3. and PODEYE intraocular lenses.
- Trial name
- PHY1803 (NCT03796624)
- Testing
- Micropure 1.2.3., PODEYE
- Where
- Czechia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Lens Subluxation
Sutureless Technique for Repositioning and Scleral Fixation of the Capsular Bag - Intraocular Lens Complex With Permanent Use of Iris Retractors
Sutureless technique for repositioning and scleral fixation of the capsular bag-intraocular lens complex with permanent use of iris retractors
- Trial name
- NCT07257172
- Testing
- Sutureless technique for repositioning and scleral fixation of the capsular bag - intraocular lens complex with permanent use of iris retractors
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Military Institute od Medicine National Research Institute
Cataract
Comparing the Visual Outcome, Visual Quality, and Satisfaction Among Three Types of Multi-focal Intraocular Lenses
The investigators are going to Investigate the comparative efficacy of the patients who underwent cataract surgery with three different multifocal IOLs.
- Trial name
- NCT04019691
- Testing
- Mix-and-Match, EDOF, Trifocal
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Cataract Senile
Evaluation of a Trifocal Lens
Evaluation of the clinical safety and effectiveness of hydrophilic acrylic intraocular lens
- Trial name
- NCT04545671
- Testing
- trifocal lens
- Where
- Germany
- Volunteers
- 389 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Anterior Chamber Inflammation
Iontophoretic Delivery of EGP-437 in Patients Who Have Undergone Cataract Surgery
Phase 2b trial evaluating the safety and efficacy of EGP-437, versus placebo using the EyeGate® II Drug Delivery System (EGDS) in patients having undergone cataract surgery with implantation of a monofocal posterior chamber…
- Conditions
- Cataract, Anterior Chamber Inflammation, Pain, Postoperative
- Trial name
- NCT03180255
- Testing
- Dexamethasone phosphate
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Cataract
Evaluation of 3 Intraocular Lenses Following Lens Extraction
The objective of this study is to evaluate the efficacy and subject satisfaction with three different FDA approved lenses for adults over 40 years of age who desire a reduction in spectacle dependence.
- Trial name
- NCT01122576
- Testing
- Crystalens AO, ReSTOR, Tecnis Multifocal IOL
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Bausch & Lomb Incorporated
Pseudoexfoliation Glaucoma, Intraocular Pressure
Efficacy and Safety of Lens Extraction in Patients With Pseudoexfoliation Glaucoma
There are several publications that have demonstrated the protective role of cataract surgery against the development of long-term glaucoma, especially in cases of pseudoexfoliation glaucoma (PXFG).
- Trial name
- NCT03494465
- Testing
- PHACOEMULSIFICATION, MEDICAL GLAUCOMA TREATMENT
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Xerencia de Xestión Integrada de Ferrol
Cataract, Lens Opacities
Comparison of Clinical Outcomes on Trifocal IOLs FineVision POD F GF and FineVision POD F in Asian Eyes
Prospective, randomised, controlled, single-surgeon, single-center clinical study to compare the clinical outcomes of two trifocal IOLs with different material (hydrophobic and hydrophilic) from the same manufacturer.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1706 (NCT03306355)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Philippines
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
A-constant Optimization of a Toric Monofocal IOL
The study is a prospective series study to determine the IOL constant of a hydrophilic toric monofocal intra-ocular lens (IOL)
- Trial name
- NCT04944238
- Testing
- Ankoris
- Where
- Belgium
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
CAtaract ASSessment of IntrOcular Lens Objective PErformancE
Prospective, interventional, non-invasive, monocentric, longitudinal, non-randomized study
- Trial name
- CASSIOPEE (NCT06168617)
- Testing
- Performance tasks in daily life
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Cataracts
Safety and Effectiveness of the Calhoun Vision Light Adjustable Intraocular Lens (LAL)
The primary objective of this study is to evaluate, for the visual correction of aphakia, the safety and effectiveness of the Calhoun Vision Light Adjustable intraocular lens (LAL) and Light Delivery Device (LDD) in treating…
- Trial name
- NCT00845520
- Testing
- Lens implantation +1.00 D postop target, Lens implantation -1.00 D postop target, Lens implantation 0.00 D postop target
- Where
- 6 sites in United States, Mexico
- Volunteers
- 74 people
- Sponsor
- Calhoun Vision, Inc.
Cataract
Stability of Secondary Intraocular Lenses With no Capsular Support
Assessment and differences in the centration, tilt and wobble of two secondary IOLs without capsular support.
- Trial name
- NCT06345846
- Testing
- IFIOL, SFIOL
- Where
- Austria
- Volunteers
- 82 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Cataract, Presbyopia
MULTICENTER, DOUBLE-ARM, PATIENT AND ASSESSOR-MASKED, PROSPECTIVE, RANDOMIZED CLINICAL TRIAL TO COMPARE VISUAL PERFORMANCE OF NEGATIVE AND NEUTRAL ASPHERIC MONOFOCAL INTRAOCULAR LENSES
The purpose of this study is to compare the binocular distance, intermediate, and near visual acuity and patient reported outcomes of the Johnson \&Johnson Eyhance and Bausch \& Lomb enVista IOLs.
- Trial name
- NCT07385014
- Testing
- Neutral Aspheric Monofocal IOL, Negative Aspheric Monofocal IOL
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Milton S. Hershey Medical Center
Cataracts
Modified Intraocular Lens to Reduce Eye Inflammation After Cataract Surgery in Uveitis Patients
This study will test the effectiveness of an intraocular lens treated with heparin in reducing or preventing inflammation after cataract surgery in patients with uveitis.
- Trial name
- NCT00001311
- Testing
- heparin-surface modified intraocular lens
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Eye Institute (NEI)
Light Adjustable Lens, Objective Depth of Focus
Objective Depth-of-Focus Changes During Light Adjustable Lens UV Adjustments
This observational pilot study will examine how a person's vision changes during the routine adjustment and finalization of a Light Adjustable Lens (LAL) after surgery.
- Trial name
- NCT07868003
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Clarity Eye Institute
Cataract
A Clinical Investigation of the ClarVista HARMONI™ Modular Intraocular Lens Implant Following Cataract Surgery
The main objectives of this feasibility study were: To demonstrate the feasibility of HARMONI Modular Intraocular Lens (HMIOL) implantation and assembly in subjects undergoing cataract surgery (All HMIOL Cohort), and To…
- Trial name
- NCT02521766
- Testing
- Harmoni Modular Intraocular Lens, Commercially Available Intraocular Lens, Optic exchange
- Where
- 2 sites in New Zealand, Philippines
- Volunteers
- 217 people
- Sponsor
- ClarVista Medical
Cataract Senile
Study on Visual Performance of a Monofocal Intraocular Lens
Retrospective/Prospective Study on Visual Performance of a Monofocal Intraocular Lens (IOL). The objective is to compare best corrected distance visual acuity (CDVA) between 1-3-month and 12- month follow-up.
- Trial name
- NCT04740788
- Testing
- Monofocal IOL
- Where
- Austria
- Volunteers
- 44 people
- Sponsor
- Carl Zeiss Meditec AG