Clinical trials: Intraocular Lenses
Aphakia
Clinical Study of a UV-Absorbing Acrylic Posterior Chamber Intraocular Lens
The purpose of this study is to assess the safety and efficacy of the HMY Model YA-60BB Intraocular Lens (IOL) when implanted in the posterior chamber of the human eye for the optical correction of aphakia following cataract…
- Trial name
- HMY (NCT00625313)
- Testing
- HMY Model YA-60BB IOL
- Where
- United States
- Volunteers
- 617 people, healthy volunteers welcome
- Sponsor
- Hoya Surgical Optics, Inc.
Cataract, Lens Opacities
Clinical Study to Investigate Visual Performance of a Hydrophobic Monofocal IOL After Bilateral Implantation
Prospective, non-randomised, open, controlled, single-center post-market clinical follow study about Micropure 1.2.3 IOL.
- Trial name
- PHY1801 (NCT03423524)
- Testing
- Micropure 1.2.3.
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Lens Diseases
Accuracy of Intra Ocular Lens CARLEVALE Calculation
The purpose of this study is to assess the accuracy of intra ocular lens power calculation using the new Carlevale sutureless scleral fixation posterior chamber intra ocular lens.
- Trial name
- NCT05368870
- Testing
- Carlevale implantation
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Poitiers University Hospital
Cataract, Corneal Astigmatism
Clinical Trial of a Hydrophilic EMV Toric Lens RAO210T in the Correction of Aphakia and Corneal Astigmatism
The objectives of the clinical investigation are to determine the safety and performance of the RayOne EMV Toric (Model RAO210T) following unilateral implantation and approximately 6 months (120 to 180 days) of post-operative…
- Trial name
- NCT05985304
- Testing
- RayOne EMV Toric IOL, RayOne Monofocal IOL, Cataract Surgery
- Where
- 9 sites in United States
- Volunteers
- 274 people
- Sponsor
- Rayner Intraocular Lenses Limited
Cataracts
Contralateral ReSTOR / Monofocal or Phakic Eye
Bilateral evaluation of unilateral implantation of ReSTOR and contralateral monofocal or phakic eye.
- Trial name
- NCT00731640
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Alcon Research
Cataract Senile
Prospective Clinical Study of Preoperative and Postoperative Unilateral Mild Cataract Patients
This is to compare preoperative and postoperative binocular functional vision in patients with unilateral intraocular len（IOL） in one eye and mild cataract in the fellow eye.
- Trial name
- NCT04266847
- Testing
- monofocal IOL,bifocal IOL,or trifocal IOL
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Cataract
Clinical Study to Evaluate the Safety and Performance of the enVista® One-Piece Hydrophobic Acrylic Trifocal Intraocular Lens in Subjects Undergoing Cataract Extraction
The objective of the study is to evaluate the safety and performance of the enVista trifocal intraocular lens when implanted in the capsular bag.
- Trial name
- NCT04224155
- Testing
- enVista MX60EFH trifocal intraocular lenses (IOLs), enVista MX60E monofocal intraocular lenses (IOLs)
- Where
- 9 sites in Canada
- Volunteers
- 165 people
- Sponsor
- Bausch & Lomb Incorporated
Macular Degeneration
Influence of Blue Light Filtering Intraocular Lenses on Daytime Levels of Melatonin
The "blue light hazard" has been reported to cause retinal damage (oxidative stress), particularly to the central fovea due to its energetic, shorter wavelength visible photons, which is why blue-light filtering intraocular…
- Trial name
- BluMel (NCT00444249)
- Testing
- White Alcon IOL, Yellow Alcon IOL, White Hoya IOL
- Where
- Austria
- Volunteers
- 136 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Intraocular Lens Complication
Re-fixating Dislocated Scleral Fixing Intra-ocular Lens
To minimize multiple manipulations and to decrease the economical burden; here, we describe how to utilize the patient's own dislocated intraocular lens to re-fixate with the sclera.
- Trial name
- NCT05278949
- Testing
- The surgical intervention
- Where
- Iraq
- Volunteers
- 5 people
- Sponsor
- Omer Othman Abdullah
Intraocular Lens Replacement
Safety and Efficacy of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification
The purpose of this study is to determine the safety and efficacy of OMS302 (the study drug) for maintaining intraoperative mydriasis in individuals undergoing Intraocular Lens Replacement (ILR) surgery.
- Trial name
- OMS302-ILR-003 (NCT01454063)
- Testing
- OMS302
- Where
- 16 sites in United States
- Volunteers
- 405 people
- Sponsor
- Omeros Corporation
Cataract, Lens Opacity
Comparison of Clinical Outcomes POD L GF vs POD F GF (PHY1707)
Prospective, randomised, controlled, single-surgeon, single-center clinical study to compare the clinical outcomes of two trifocal IOLs differing in the dominance of additional power.
- Conditions
- Cataract, Lens Opacity, Presbyopia
- Trial name
- NCT03688399
- Testing
- IOL implantation experimental, IOL implantation comparator
- Where
- Hungary
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Reading Performance in Patients With Acrysof IQ Vivity Versus Acrysof IQ
Comparison of the visual function and reading performance between the Acrysof IQ Vivity IOL, an EDOF IOL, and the monofocal Acrysof IQ.
- Trial name
- NCT05194657
- Testing
- enhanced depth of focus IOL, monofocal IOL
- Where
- Austria
- Volunteers
- 68 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Bilateral Cataract, Astigmatism
Non-comparative Trial Following Participants Implanted Bilaterally With Mini WELL Toric Ready Intraocular Lens for 6 Months After the Second Eye Implant (FUSION)
This is a multicenter, non-comparative trial following participants implanted bilaterally with the Mini WELL Toric Ready intraocular lens (IOL) for 6 months after the second eye implant.
- Trial name
- FUSION (NCT03861351)
- Testing
- Mini WELL Toric Ready intraocular lens
- Where
- 4 sites in France, Germany and 1 more
- Volunteers
- 58 people
- Sponsor
- SIFI SpA
Cataract
Visual Outcomes of Vivity in Patients With High Axial Length
The objective is to assess the visual outcomes and quality of vision of patients receiving the AcrySof® Vivity Intraocular lens (IOL), when implanted in eyes with high ocular axial length (≥24.5mm), after uneventful cataract…
- Trial name
- NCT05210569
- Testing
- Vivity
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Dr. James J. Wiens Medical Corporation
Cataract, Intraocular Lens
Comparison on Outcomes of Four IOLs in Patients With Cataracts
The objective of this study was to compare the objective visual outcomes and subjective fuctional vision of four different intraocular lens (IOL) in patients underwent cataracts surgery. This was a retrospective study.
- Conditions
- Cataract, Intraocular Lens, Visual Outcomes
- Trial name
- NCT06590272
- Testing
- TECNIS PCB00 intraocular lens, HumanOptics Diff-Aay intraocular lens, TECNIS Symfony ZXR00 intraocular len
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Shanghai 10th People's Hospital
Cataract
CAtaract ASSessment of IntrOcular Lens Objective PErformancE
Prospective, interventional, non-invasive, monocentric, longitudinal, non-randomized study
- Trial name
- CASSIOPEE (NCT06168617)
- Testing
- Performance tasks in daily life
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Cataract, Phakic Intraocular Lens Explantation
Molecular Background of Endothelial Cell Loss in Patients With Phakic Intraocular Lenses: a Tear and Aqueous Humour Analysis Study
Rationale: The number of highly myopic patients is increasing. Especially in East and Southeast Asia, up to 90% of adolescents are currently myopic.
- Trial name
- MoBack (NCT04174924)
- Testing
- Phakic intraocular lens (pIOL) explantation
- Where
- Netherlands
- Volunteers
- 126 people
- Sponsor
- Maastricht University Medical Center
Outcomes Following Restor IOL Lens Implant
Clinical Outcomes After AcrySof® ReStor IOL Surgery in Faculty Practice at UTSW Medical Center at Dallas: A Retrospective Review
To evaluate the clinical outcomes of AcrySof® ReSTOR® IOL for the Faculty Practice at UTSW Medical Center at Dallas
- Trial name
- NCT00344578
- Testing
- Restor IOL
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Cataract
DEXTENZA Compared to Topical Steroid Therapy Prior to Cataract Surgery in Patients Who Receive Premium Intraocular Lenses
The investigators seek to assess the effect of pre-operative and continued post-operative corticosteroid use on pain, patient preference, visual outcomes, and change in objective quantifiable biological parameters in patients…
- Trial name
- NCT04479748
- Testing
- Dexamethasone, Prednisolone Acetate 1% Oph Susp
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Prism Vision Group
Cataract, Astigmatism
Use of Toric Intraocular Lens to Neutralize Keratometric Astigmatism
The purpose of this study is to evaluate neutralization of keratometric astigmatism in patients with cataract and astigmatism higher than 1 diopter, with phaco surgery and the implantation of a toric intraocular lens.
- Trial name
- NCT00925886
- Testing
- Acrysof Toric one-piece intraocular lens
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Asociación para Evitar la Ceguera en México