Clinical trials: Intraocular Lenses
IOL, Cataract
Clinical Outcomes of Patients with LAL+ in At Least One Eye
The objective of this study is to collect data on bilateral pseudophakic patients implanted with the RxSight Light Adjustable Lens+ (LAL+) in at least one eye
- Trial name
- NCT06650358
- Testing
- Light Adjustable Lens+
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Frank A. Bucci, Jr., M.D.
Cataract
DEXTENZA Compared to Topical Steroid Therapy Prior to Cataract Surgery in Patients Who Receive Premium Intraocular Lenses
The investigators seek to assess the effect of pre-operative and continued post-operative corticosteroid use on pain, patient preference, visual outcomes, and change in objective quantifiable biological parameters in patients…
- Trial name
- NCT04479748
- Testing
- Dexamethasone, Prednisolone Acetate 1% Oph Susp
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Prism Vision Group
Aphakia, Cataract
Exploratory Study to Evaluate the Use of the RxSight Light Adjustable Lens (LAL) and the Light Delivery Device (LDD) to Improve Visual Outcomes
The objective of this study is to evaluate, for the visual correction of aphakia, whether the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) can be used to improve visual outcomes after performing adjustments…
- Trial name
- NCT03895034
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 66 people
- Sponsor
- RxSight, Inc.
Age Related Cataracts
Visual Performance of Clareon PanOptix vs. a Comparable Multifocal Intraocular Lens
This is a two-part, multi-center, investigator-initiated clinical study comparing visual outcomes and patient satisfaction in subjects receiving bilateral implantation of either the Clareon PanOptix intraocular lens (IOL) or a…
- Trial name
- NCT07006428
- Testing
- Clareon PanOptix or PanOptix Toric IOLs, Comparable multifocal IOL
- Where
- 3 sites in United States
- Volunteers
- 290 people
- Sponsor
- Argus Research Center, Inc.
Cataract
A Dynamic Study of Pupil Diameter After Artificial Lens Implantation in Patients With High Myopia
Age-related cataract remains the leading cause of blindness in developing countries. And, with the aging of the population in these countries, the number of cataract patients will continue to grow.
- Trial name
- NCT06505434
- Testing
- Cataract surgery
- Volunteers
- 60 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Cataract
Intraocular Steroid After Cataract Surgery Study
The use of one dose of an antibiotic and steroid injected into the eye at the end of cataract surgery is as safe and effective as the post operative use of eyedrops after cataract surgery.
- Trial name
- NCT00478764
- Testing
- intraocular triamcinolone and gatifloxicin
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Dean Health System
Refractive Assessment
Visual Performance After RESTOR Implantation
The purpose of this study is to evaluate the distance, intermediate, and near vision after aspheric multifocal diffractive AcrySof® ReSTOR SN6AD1 intraocular lens (IOL) implantation.
- Trial name
- NCT01065064
- Testing
- RESTOR IOL
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Oftalmologico de Brasilia
Ocular Hypertension
Intraocular Pressure in Ocular Hypertensives With Scleral Lens Wear
The purpose of this study is to determine if short-term wear of a spherical rigid contact lens, called a scleral lens, will raise intraocular pressure in ocular hypertensive patients.
- Trial name
- NCT04442464
- Testing
- Scleral Lens
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Cataract Extraction
Comparison of Acular LS With Lotemax to Prevent Inflammation After Cataract Surgery and Intraocular Lens Implantation
The purpose of this study is to compare the effectiveness of Acular LS® and Lotemax® in the prevention of inflammation in the eye after cataract surgery. Acular LS is made by Allergan, Inc.
- Trial name
- NCT00366691
- Testing
- Acular LS, Lotemax
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Refractive Lens Exchange
RLE Outcomes With Bilateral Implantation of Odyssey IOLs
This study is a single center, ambispective study of visual outcomes after successful bilateral implantation of the Odyssey IOL. Subjects will be assessed at least 2 months postoperatively at a single visit.
- Trial name
- NCT06979557
- Testing
- Odyssey IOL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mann Eye Institute
Cataract, Cataract Surgery
Binocular and Monocular Distance-Corrected Visual Performance and Defocus Characteristics of Clareon Truplus Intraocular Lens (IOL)
This study aims to generate data that characterizes visual outcomes, including the binocular distance-corrected intermediate visual acuity (DCIVA) at 66cm or defocus behavior, of the Clareon TruPlus modified monofocal intraocular…
- Conditions
- Cataract, Cataract Surgery, Cataract Bilateral, Cataract (Post-operative Cataract Surgery Follow-up)
- Trial name
- BMVDI (NCT07589894)
- Testing
- Clareon TruPlus IOL
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Colvard Kandavel Eye Center
Cataract
Comparison of Gemini III Rev 2 Implanted in Conjunction With an Approved IOL vs Eyes Implanted With an Approved IOL
This study is a prospective, observational, randomized, controlled, paired eye, subject-masked design.
- Trial name
- NCT04059796
- Testing
- Omega Gemini III Rev 2 Device, Control Eye
- Where
- Costa Rica
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Omega Ophthalmics
Cataract
The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1
To assess the safety and effectiveness of treatment with an intracanalicular dexamethasone (0.4mg) insert in the operating room following cataract surgery/intraocular lens implant (IOL) compared to insertion 1-day post-op.
- Trial name
- NCT05100186
- Testing
- Dexamethasone 0.4 MG [Dextenza]
- Volunteers
- 50 people
- Sponsor
- Joseph Kavanagh, MD
Cataract, Lens Opacities
Clinical Study to Compare Visual Performance of Two Trifocal IOLs
Prospective, randomised, controlled, single-surgeon, single-center post-market clinical follow up study to compare the clinical outcomes of two trifocal IOLs with different material
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1702 (NCT03347981)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Spain
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Glaucoma, Cataract
IOP and Ocular Biometrics Changes After Phacoemulsification in Glaucoma Patients and Controls
Effect of phacoemulsification on intraocular pressure has been studied with variable results.Furthermore, effect of phacoemulsification on ocular biometrics including anterior chamber depth and angle opening distance has also…
- Trial name
- NCT04334473
- Testing
- phacoemulsification and Intraocular lens implantation, Ultrasound Biomicrosopy (UBM)
- Where
- Egypt
- Volunteers
- 37 people
- Sponsor
- Mai Nasser Abd Elmohsen
Cataract, Lens Opacities
Comparison of ISOPURE and EYHANCE (Switzerland)
This is a prospective randomised open-label study with the aim to compare the visual performance of the premium monofocal Isopure IOL versus the extended depth of focus Eyhance® IOL after phaco-emulsification cataract surgery.
- Trial name
- PHY2301 (NCT05875922)
- Testing
- IOL implantation experimental (ISOPURE 1.2.3.), IOL implantation active comparator (TECNIS Eyhance)
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract Senile
Extended Depth of Focus (EDF) Intraocular Lens (IOL) Versus Monofocal Intracoular Lens (IOL)
Extended depth of focus (EDF) intraocular lens (IOL) versus Monofocal intraocular lens (IOL)
- Trial name
- NCT07092020
- Testing
- EDF, Monofocal IOL
- Where
- 14 sites in Bulgaria, Czechia and 2 more
- Volunteers
- 220 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Glaucoma
Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution
This trial is a randomized study to evaluate and compare two doses of the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle…
- Conditions
- Cataract, Glaucoma, Ocular Hypertension
- Trial name
- Tigris (NCT06120842)
- Testing
- Bimatoprost Implant System (High Dose), Bimatoprost Implant System (Low Dose), Timolol Maleate Ophthalmic Solution, 0.5%
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- SpyGlass Pharma, Inc.
Cataract, Lens Opacities
Visual Performance, Patient Satisfaction and PCO Rate After Implantation of a Trifocal Hydrophobic IOL
Prospective, controlled, single-surgeon, single-center post-market clinical follow up study to investigate the clinical outcomes of a hydrophobic trifocal IOL (PhysIOL POD F GF)
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1703 (NCT03306342)
- Testing
- IOL implantation experimental
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract, Astigmatism
A Trial of Toric Versus Non-toric Intraocular Lenses in Phacoemulsification Cataract Surgery
This is a randomised controlled trial that formally compares intra-ocular lenses, which can be used in cataract surgery, one of which is the standard 'monofocal' lens, and the other is the newer toric lens which can correct…
- Trial name
- NCT01712503
- Testing
- Phacoemulsfication cataract surgery and intra-ocular lens implant
- Where
- United Kingdom
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Western Sussex Hospitals NHS Trust