Clinical trials: Intraocular Lenses
Cataract, Presbyopia
The Visual Performances of a Progressive Multifocal Intraocular Lens With Extended Depth of Focus
The purpose of this observational, non-controlled, multicenter trial with a retrospective design is to evaluate the visual performance of one cohort of patients who received the EDOF MINI WELL® intraocular lenses following…
- Trial name
- NCT02740010
- Testing
- EDOF Mini WELL Ready IOL
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- SIFI SpA
Cataract
Evaluation of Safety and Performance of the EyenableTM Intraocular Lens for Cataract Treatment
Cataract is characterized by the loss of the normal transparency of the crystalline lens. It is a progressive, chronic disease that affect individuals over the age of 50. It is the leading cause of blindness around the world.
- Trial name
- NCT06223113
- Testing
- EyenableTM PA60AS1 IOL
- Volunteers
- 200 people
- Sponsor
- Xi'an Eyedeal Medical Technology Co., Ltd
Myopia
Implantable Phakic Lens (IPCL) VS Implantable Collamer Lens
Phakic intraocular lenses (pIOL) of different designs and materials have been used effectively instead of corneal refractive surgery in certain situations.
- Trial name
- NCT04624035
- Testing
- Implantable Collamer Lens (ICL) in treatment of myopia in adults., Implantable Intraocular Lens (IPCL) in treatment of myopia in adults.
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Cataract
Spectacle Independence and Overall Satisfaction With AcrySof® Panoptix® Toric Intraocular Lens
The study was designed to assess the spectacle independence and satisfaction of patients receiving the AcrySof® Panoptix® Toric intraocular lens (IOL) after uneventful cataract surgery.
- Trial name
- NCT04128514
- Testing
- Panoptix Toric
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Eye Center of North Florida
Primary Open Angle Glaucoma, Ocular Hypertension
Study of LL-BMT1 in Patients With Elevated Intraocular Pressure
This is an open-label, Phase 2a clinical study of LL-BMT1 in patients with primary open-angle glaucoma and ocular hypertension. Study subjects will be treated for 7 days with a single dose of LL-BMT1.
- Trial name
- NCT04747808
- Testing
- LL-BMT1
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- MediPrint Ophthalmics, Inc.
Aphakia
Evaluation of the Tecnis™ Multifocal and Crystalens™ Accommodating Intraocular Lenses
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and Crystalens™ AO Aberration-free Accommodating intraocular lens (IOLs) 6 months after post cataract surgery.
- Trial name
- NCT01061281
- Testing
- Tecnis MF IOL, Crystalens AO IOL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Innovative Medical
Posterior Capsule Opacification After Phacoemulsification and IOL Implantation
Long-term Evaluation of Single-piece ACrysof IOL Implantation on Development of Posterior Capsule Opacification
Although contemporary cataract surgery has made tremendous strides in technological advancement, posterior capsular opacification (PCO) is still the most frequent long-term complication leading to decreased visual functions and…
- Trial name
- NCT01820065
- Testing
- Cataract surgery with IOL implantation
- Where
- India
- Volunteers
- 390 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract
Evaluating Patient Satisfaction After Cataract Surgery With Multifocal Intraocular Lens
Multifocal lens allow most patients to be spectacle-free after cataract surgery. Most studies published up-to-date have focused on visual acuity, but not on patient-reported outcomes.
- Trial name
- NCT03787576
- Testing
- Cataract surgery
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Clínica Rementería
Cataract
Glistenings and PCO Evaluation for the Envista MX60
Posterior capsule opacification (PCO) and glistenings development is among the primary reasons for sub-optimal visual capacity following cataract extraction surgery.
- Trial name
- NCT02698943
- Testing
- Phacoemulsification
- Volunteers
- 60 people
- Sponsor
- Democritus University of Thrace
Refractive Error Correction
Clinical Outcomes of the Use of a Femtosecond Laser on an Implanted Intraocular Lens
This is a prospective non-randomized patient controlled single center study which is designed to evaluate the clinical outcomes of the treatment of an implanted intraocular lens using a low-energy femtosecond laser for refractive…
- Trial name
- NCT07473557
- Testing
- Device
- Where
- Panama
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Angle Closure Glaucoma
Laser Iridotomy Versus Phacoemulsification in Acute Angle Closure
This is a randomised controlled clinical trial to compare laser peripheral iridotomy (LPI) and primary phacoemulsification with intra-ocular lens implantation (phaco/IOL) in the treatment of acute primary angle-closure glaucoma…
- Trial name
- NCT00350428
- Testing
- Laser Preipheral Iridotomy and phacoemulsification
- Where
- Singapore
- Volunteers
- 70 people
- Sponsor
- Singapore National Eye Centre
Cataract With Pre-existing Regular Corneal Astigmatism
Influence of Implantation Technique on Rotational Stability of a Frosted-Haptic Toric Intraocular Lens: A Prospective Contralateral-Eye Study
This prospective, randomized contralateral-eye study evaluates whether the implantation technique influences the rotational stability and refractive outcomes of the TECNIS Eyhance™ Toric II intraocular lens (IOL) during cataract…
- Trial name
- NCT07768722
- Testing
- OVD-assisted Implantation, BSS-assisted hydroimplantation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Patients Implanted With Monofocal Intraocular Lens
Prospective Evaluation of Near and Intermediate Visual Outcomes With Monofocal Intraocular Lenses: The Mast Study
The purpose of this study is to evaluate the near and intermediate visual outcomes of patients who have undergone routine cataract surgery (removal of cloudy crystalline lens) with phacoemulsification (the break-up and removal of…
- Trial name
- NCT01191515
- Testing
- Monofocal Intraocular Lenses
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Pseudophakia, Refractive Error
IOL Power Formula Prediction Accuracy at the Extremes of Axial Length: A Prospective Outcome Verification Study
This single-center, prospective, cross-sectional study evaluates how accurately eight modern intraocular lens (IOL) power calculation formulas predicted the postoperative refractive result in eyes with extreme axial length after…
- Trial name
- FORMULEX-OV (NCT07724795)
- Testing
- Standardized postoperative outcome visit
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Vienna Hospital Association
Capsule Opacification, Tissue Adhesions
Evaluate Capsular Apposition to Intraocular Lens
In this study, the investigators examined the capsule-IOL interaction including anterior and posterior capsule adhesion, contact between posterior capsule and the posterior edge of intraocular lense (IOL), configuration of…
- Conditions
- Capsule Opacification, Tissue Adhesions, Aphakia - Lens Capsule Present, Opacification of Intraocular Lens
- Trial name
- NCT01605812
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Wenzhou Medical University
Cataract
Medications Effect on Lenstar Measurements
Prior to cataract surgery the lens must be calculated to appropriately fit a patient for the intraocular lens implant. Lenstar is an optical biometer that calculates the axial length, keratometry, lens thickness, pupillometry…
- Trial name
- NCT02780063
- Testing
- Lenstar Biometer
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Pseudophakia
An Open-Label Evaluation of Degree of Accommodation in Pseudophakic Patients Bilaterally Implanted With Monofocal Intraocular Lenses
This study will determine the ability of three different intraocular lenses to accommodate in patients who have previously undergone bilateral intraocular lens implantation.
- Trial name
- NCT01004549
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Cataract
Prospective Clinical Study of Unilateral or Bilateral Implantation of Intraocular Lens in Cataract Patients
This is to evaluate the satisfaction of patient and postoperative functional vision of unilateral or bilateral Implantation of intraocular lens（IOLs） in cataract patients.
- Trial name
- NCT04265820
- Testing
- unilateral implantation of IOL, bilateral implantation of IOL
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Cataract Surgery, Glaucoma Surgery
PREFERENTIAL Study
To determine patient preference for the dexamethasone insert or topical prednisolone therapy through at Day 45 as measured by - Modified COMTOL survey.
- Trial name
- NCT04563559
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate 1% Ophthalmic Suspension [PRED FORTE]
- Sponsor
- Duke University
Vitrectomy, Retinal Detachment
Pars Plana Vitrectomy With 25-gauge 20000 Cpm, Bevel-tip Cutter
Report efficiency and clinical outcomes using 25-gauge, bevel-tip, 20000 cut per minute vitrectomy probe among eyes with various vitreo-retinal diseases
- Conditions
- Vitrectomy, Retinal Detachment, Vitreous Hemorrhage, Macular Holes
- Trial name
- HYPE (NCT04404296)
- Testing
- 25-gauge, bevel-tip, 20000 cut per minute pars plana vitrectomy
- Where
- Philippines
- Volunteers
- 50 people
- Sponsor
- Peregrine Eye and Laser Institute