Clinical trials: Intraocular Lenses
Cataract
Observational, Prospective Clinical Investigation on Mini 4 Ready Intraocular Lens
Cataract surgery presents an extremely high success rate in improving vision and quality of life and it is currently the most commonly performed ophthalmic surgery, especially considering its growing utility in the aging…
- Trial name
- NCT06093880
- Testing
- monofocal intraocular lens
- Where
- Italy
- Volunteers
- 125 people
- Sponsor
- SIFI SpA
to Compare the Effect of Two Types of IOLs, on the Incidence of Cystoid Macular Edema
The Effect of a Blue Light Filtering IOL
To compare the effect on blood retinal barrier disruption 3 and 12 months after implantation of either a blue light filtering intraocular lens(blue-filtering IOL) or an ultraviolet light filtering intraocular lens(UV-filtering…
- Conditions
- to Compare the Effect of Two Types of IOLs, on the Incidence of Cystoid Macular Edema, After Cataract Surgery
- Trial name
- NCT00571831
- Testing
- intraocular lens implantation
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Showa University
Pseudophakic Bullous Keratopathy, Anterior Chamber Intraocular Lens
Descemet Membrane Endothelial Keratoplasty Combined With Intraocular Lens Exchange: Sequential Versus Combined Surgery
Surgical treatment of corneal endothelial decompensation in the presence of an anterior chamber intraocular lens (AC IOL) is technically challenging.
- Trial name
- NCT04344522
- Testing
- Descemet membrane endothelial keratoplasty DMEK, IOL exchange, iridoplasty
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
The Comparison of IOL Formulas in Eyes With PCE≥15um Undergoing Cataract Surgery
Comparison of IOL Formulas in Eyes With PCE≥15µm
The goal of this observational study is to evaluate the long-term refractive outcomes of advanced intraocular lens (IOL) power calculation formulas in cataract patients with posterior corneal elevation (PCE ≥ 15 μm).
- Trial name
- NCT07346456
- Testing
- Intraocular lens calculation formulas
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Cataract
Clinical Safety and Efficacy of CT ASPHINA 509 Lenses
Clinical safety and efficacy of CT ASPHINA 509 IOLs after implantation
- Trial name
- UVEA509 (NCT03145116)
- Testing
- CT ASPHINA 509
- Where
- Germany
- Volunteers
- 95 people
- Sponsor
- Carl Zeiss Meditec AG
Intraocular Lens Dislocation
Late In-the-bag intraOcular Lens dislocatioN Surgery
Overall aim of the study is to compare the safety and efficacy of two different surgical methods to treat Late In-the-bag intraocular lens dislocation.
- Trial name
- LION (NCT03276104)
- Testing
- IOL repositioning, IOL exchange
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Cataract
A Study of MELT-300 (Midazolam and Ketamine Sublingual Tablets) for Sedation and Intraoperative Ocular Analgesia in Participants Undergoing Cataract Extraction With Lens Replacement (CELR)
The primary purpose of the study is to evaluate the efficacy and safety of MELT-300 (Midazolam and Ketamine Sublingual Tablets) and the contribution of midazolam and ketamine components to sedation and during the surgery or…
- Trial name
- NCT05133518
- Testing
- MELT-300, Midazolam alone, Ketamine alone
- Where
- 3 sites in United States
- Volunteers
- 338 people
- Sponsor
- Melt Pharmaceuticals
Cataract
Laser Treatment of the Crystalline Lens
The use of a femtosecond laser in cataract surgery that gives equivalent or improved results comapred to conventional phaco-emulsification surgery.
- Trial name
- NCT01001117
- Testing
- LensAR laser surgery, Phaco-emulsification cataract surgery
- Where
- Mexico
- Volunteers
- 75 people
- Sponsor
- LensAR Incorporated
Cataract
Evaluation Of Bilateral Tecnis Multifocal Versus ReSTOR 3D Intraocular Lenses
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR intraocular lenses (IOLs) 6 months post cataract surgery.
- Trial name
- NCT01061918
- Testing
- Tecnis MF, ReSTOR
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Innovative Medical
Aphakia
A Real-World Evidence (RWE) Long-Term Follow-Up Study to Assess Outcomes of Alcon Monofocal Intraocular Lenses
The purpose of this post-market clinical follow-up (PMCF) study is to describe the long-term safety and performance of AcrySof Single-Piece and AcrySof Multi-Piece monofocal intraocular lenses (IOLs).
- Trial name
- NCT05799950
- Testing
- AcrySof single-piece IOL, AcrySof multi-piece IOL
- Where
- 7 sites in United States, Puerto Rico
- Volunteers
- 138 people
- Sponsor
- Alcon Research
Cataract
A Study Assessing Safety and Efficacy of MD-15 Intraocular Lens in Patients With Aphakic Eye After Cataract Surgery
To evaluate safety and efficacy of MD-15 intraocular lens implanted into the aphakic eyes
- Trial name
- NCT02888210
- Testing
- MD-15 Intraocular Lens
- Where
- Japan
- Volunteers
- 110 people
- Sponsor
- Santen Pharmaceutical Co., Ltd.
Cataract
Long-term With a Trifocal Intraocular Lens
The main aims of this study were to evaluate the patient reported outcomes (PROs), safety and efficacy, after 6-year (66 - 78 months) from the binocular implantation of the AT LISA tri 839MP.
- Trial name
- NCT04861909
- Testing
- AT LISA tri 839MP
- Where
- Spain
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Qvision, Ophthalmology Department
Cataract, High Myopia
Visual Outcomes of an Enhanced Monofocal Intraocular Lens Targeted for Monovision in Highly Myopic Eyes: a Randomized Controlled Trial
The goal of this clinical trial is to evaluate whether an enhanced monofocal intraocular lens targeted for monovision can improve visual outcomes in patients with cataract and high myopia (axial length ≥ 26 mm).
- Trial name
- NCT07168109
- Testing
- Enhanced monofocal intraocular lens implantation (monovision strategy), Enhanced monofocal intraocular lens implantation (bilateral myopia strategy)
- Volunteers
- 66 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract
A Comparison of Visual Function After Bilateral Implantation of Presbyopia-correcting Intraocular Lenses (IOLs)
The purpose of this study is to prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with the AcrySof® IQ ReSTOR® +3 versus those bilaterally implanted with the…
- Trial name
- NCT01166971
- Testing
- ReSTOR +3, Tecnis MF
- Where
- 3 sites in United States
- Volunteers
- 65 people
- Sponsor
- Alcon Research
Cataract
Safety and Effectiveness of a Multifocal Intraocular Lens (IOL)
To evaluate the safety and effectiveness of the ZM900 Tecnis Multifocal lens. Results from two studies (an original study with 125 multifocal and 123 monofocal subjects, protocol DIOL-101-TCNS, and an expansion study with 222…
- Trial name
- NCT00747565
- Testing
- Tecnis ZM900 Multifocal Intraocular Lens, CeeOn 911A monofocal IOL
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Cataract
Evaluate the Safety and Effectiveness of the enVista® One-Piece Hydrophobic Acrylic Trifocal Intraocular Lens
The objective of the study is to evaluate the safety and effectiveness of the enVista trifocal intraocular lens when implanted in the capsular bag.
- Trial name
- NCT03603600
- Testing
- enVista MX60E, enVista MX60EF
- Where
- 23 sites in United States
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Comparison of 2 Diffractive Trifocal IOLs
Compare two commercially available bilateral implanted diffractive trifocal lenses (Zeiss AT Lisa tri vs. Rayner trifocal) after cataract surgery concerning visual function and spectacle independence.
- Trial name
- NCT03748381
- Testing
- Cataract surgery
- Where
- Austria
- Volunteers
- 44 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Cataract, Spherical Aberrations
Optical Quality After Implantation of a Spherical or Aspherical Intraocular Lens in Hypermetropic Patients
The purpose of this study is to evaluate differences in the depth of focus after implantation of a spherical or aspheric IOL in hypermetropic and emmetropic patients.
- Conditions
- Cataract, Spherical Aberrations, Intraocular Lenses, Depth of Focus
- Trial name
- NCT01995630
- Testing
- AMO Tecnis ZA9003, AMO Sensar AR40e
- Where
- Austria
- Volunteers
- 62 people
- Sponsor
- Medical University of Graz
Cataract, Presbyopia
Clinical Evaluation and Comparison of the Tecnis Symfony Optiblue and Tecnis Symfony IOLs
The goal of this clinical study is to compare the Tecnis Symfony Optiblue intraocular lens implant to the Tecnis Symfony intraocular lens implant in patients over 22 years old with cataracts in both eyes.
- Trial name
- NCT06567834
- Testing
- Tecnis Symfony Optiblue/Tecnis Symfony Optiblue Toric (Models ZXR00V/ZXW150), Tecnis Symfony/Tecnis Symfony Toric (Models ZXR00/ZXT150)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Empire Eye and Laser Center
Presbyopia, Myopia
Presbyopic Phakic Intraocular Lens for Myopia Correction
This is a prospective single-center study of implantations of the presbyopic version of phakic intraocular lens IPCL (EyeolUK, United Kingdom).
- Trial name
- NCT03836898
- Testing
- Presbyopic posterior chamber phakic intraocular lens IPCL
- Where
- Czechia
- Volunteers
- 10 people
- Sponsor
- Gemini Eye Clinic