Clinical trials: Intraocular Lenses
Intraocular Lens Replacement
Safety, Efficacy and Pharmacokinetics of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification
The purpose of this study is to determine the safety, efficacy and pharmacokinetics of OMS302 (the study drug) for maintaining intraoperative mydriasis and preventing post operative pain in individuals undergoing Intraocular Lens…
- Trial name
- OMS302-ILR-004 (NCT01579565)
- Testing
- OMS302
- Where
- 14 sites in United States, Netherlands
- Volunteers
- 416 people
- Sponsor
- Omeros Corporation
GLAUCOMA 1, OPEN ANGLE, D (Disorder), Cataract
Comparison of Visual Outcomes and Patient Satisfaction in Mild to Moderate Glaucoma Patients Undergoing Cataract Surgery With EDOF Versus Monofocal IOLs
Cataract is the leading cause of reversible vision loss, while glaucoma remains the primary cause of irreversible blindness, often impairing contrast sensitivity (CS), glare tolerance, and dark adaptation.
- Trial name
- NCT07436871
- Testing
- Cataract surgery (Monofocal intraocular lens implantation), cataract surgery (Extended depht of focus intraocular lens implantation)
- Volunteers
- 74 people
- Sponsor
- OMIQ Research
Cataract
Lenstec Tetraflex Accommodating Posterior Chamber Intraocular Lens (IOL) Clinical Investigation
The purpose of the following clinical protocol is to evaluate the safety and effectiveness of the Lenstec Tetraflex Accommodating Posterior Chamber Intraocular Lens (IOL) for the protocol inclusion/exclusion criteria.
- Trial name
- NCT00969371
- Testing
- posterior chamber IOL implantation, Experimental TetraFlex Study IOL
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Cataract, Intraocular Lens Implantation
The Femtosecond Laser in Residency Training (FLIRT) Pilot Study
This pilot study aims to primarily assess the rate of complication of anterior vitrectomy for patients undergoing femtosecond laser-assisted (FLA) cataract extraction and intraocular lens placement (CEIOL) compared to manual…
- Trial name
- FLIRT (NCT03115216)
- Testing
- FLA-CEIOL, CEIOL
- Sponsor
- University of Southern California
Cataract
Revised Capsular Polishing and Its Impact on the Positioning of the Intraocular Lens and Visual Quality Following Femtosecond Laser-assisted Cataract Surgery
This study aims to investigate the impact of improved capsular polishing on the long-term stability of effective lens position (ELP) and visual quality in patients following femtosecond laser-assisted cataract surgery combined…
- Trial name
- ELPVQFLACS (NCT06517095)
- Testing
- improved capsular polishing, the conventional I/A polishing
- Where
- China
- Sponsor
- Xi'an People's Hospital (Xi'an Fourth Hospital)
Intraocular Lens, Cataract
Evaluation of Safety and Effectiveness of an IOL With a Virtual Aperture Optic
Cataracts are cloudy areas in the lens of the eye that can cause changes in vision. Symptoms of cataracts include cloudy or fuzzy vision and sensitivity to glare.
- Conditions
- Intraocular Lens, Cataract, Presbyopia
- Trial name
- NCT05955846
- Testing
- cataract surgery, implantation of device IOL FG-80030.1
- Where
- 8 sites in Portugal, Spain and 1 more
- Volunteers
- 60 people
- Sponsor
- Z Optics, Inc.
Cataract
Comparison of a New EDOF-IOL With a Standard-EDOF-IOL
Comparison of the new extended depth of focus (EDOF) intraocular lens (IOL) ARTIS ACTIVE, which is designed as a twinset of IOLs, with the standard EDOF IOL AT Lara .
- Trial name
- NCT03921762
- Testing
- Cataract surgery with Artis Active IOLs, Cataract surgery with AT Lara IOLs
- Where
- Austria
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Cataract, Presbyopia
Clinical Investigation of the Visual Outcomes and Safety of a Trifocal Intraocular Lens (IOL) in a Korean Population
The purpose of this study is to confirm the effectiveness of the investigational lens in a Korean population, especially for visual performance, quality of vision, and subject satisfaction with the visual outcome, as well as the…
- Trial name
- NCT03268746
- Testing
- AcrySof IQ PanOptix Multifocal IOL
- Where
- 4 sites in South Korea
- Volunteers
- 52 people
- Sponsor
- Alcon Research
Cataract
Post Marketing Clinical Evaluation Assessing the Visual Performance of Hanita Lenses "Intensity SL" Intraocular Lens
This clinical study will assess the safety and performance of Intensity SL IOL, 1 year post operation. The study will also evaluate the patient satisfaction of the implanted patients.
- Trial name
- Post-op (NCT06075459)
- Where
- Argentina
- Volunteers
- 60 people
- Sponsor
- Hanita Lenses
Inflammation, Pain
Efficacy and Safety of XG-102 in Reduction of Post-cataract Surgery Intraocular Inflammation and Pain
The purpose of this study is to evaluate the clinical efficacy and safety of XG-102 (900µg) compared to vehicle in the treatment of subjects with inflammation and pain following cataract surgery.
- Conditions
- Inflammation, Pain, Cataract
- Trial name
- NCT02508337
- Testing
- XG-102
- Where
- United States
- Volunteers
- 309 people
- Sponsor
- Xigen SA
Cataract Congenital
Multifocal vs Monofocal IOL in Congenital Cataract Surgery
The aim of this study is to evaluate long-term outcome after congenital cataract surgery comparing results achieved with multifocal and monofocal IOLs.
- Trial name
- NCT04872829
- Testing
- cataract surgery
- Volunteers
- 43 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Cataract, Corneal Astigmatism
Clinical Investigation of Two Tecnis Investigational Lenses
This study is a 6-month, prospective, multicenter, randomized (1:1:1), subject-masked and evaluator-masked, bilateral clinical investigation of the TECNIS IOL Models C1V000 and C2V000 versus the TECNIS Eyhance™ Model ICB00 IOL.
- Trial name
- NCT04890249
- Testing
- Investigational IOL Model C1V000, Investigational IOL Model C2V000, Control IOL Model ICB00
- Where
- 8 sites in Australia, New Zealand
- Volunteers
- 221 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Corneal Endothelial Cells
Corneal Endothelial Assessment After Posterior Chamber Phakic Intraocular Lens Implantation
our primary aim of the work to assess the effect of phakic IOL implantation on corneal endothelium. we also used the specular microscope to assess the corneal endothelium
- Trial name
- NCT06849375
- Testing
- phakic IOL implantation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Cataract, Presbyopia Correction
Night Driving After Trifocal Versus Monofocal IOL Implantation
This prospective observational cohort study will compare night-driving visual difficulty and visual disturbances after bilateral implantation of an Alcon trifocal intraocular lens or an Alcon monofocal intraocular lens in adults…
- Trial name
- TriIOL (NCT07755189)
- Testing
- AcrySof IQ PanOptix TFNT00 Trifocal Intraocular Lens, Alcon Monofocal Intraocular Lens
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Jin Yang
Aphakia, Corneal Astigmatism
Clinical Investigation of an AcrySof IQ PanOptix Toric Intraocular Lens
The purpose of this study is to evaluate the effectiveness and safety of the TFNT20 low cylinder power intraocular lens when implanted in the eye to replace the natural lens following cataract removal.
- Trial name
- NCT04542525
- Testing
- ACRYSOF IQ PanOptix Toric Trifocal IOL, Cataract surgery
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- Alcon Research
Cataract
Multicentric Clinical Investigation to Assess Safety and Performance of Lux HighAdd IOL
The study purpose is to demonstrate safety and performance of bilateral implantation of LuxHighAdd intraocular lens compared with the LuxGood Monofocal lens.
- Trial name
- HIGHADD (NCT06446817)
- Testing
- LuxHighAdd IOL, LuxGood IOL
- Where
- 3 sites in France
- Volunteers
- 57 people
- Sponsor
- Cutting Edge SAS
Cataract, Age-related Cataract
Association Between Light Spectrum and Survival After Cataract Surgery
This study was a retrospective observational cohort analysis of subjects aged 65 years and older, who underwent bilateral cataract surgery within a single (15 hospital) healthcare system, to determine the association between type…
- Conditions
- Cataract, Age-related Cataract, Circadian Rhythm Disorders, Glaucoma
- Trial name
- NCT04187157
- Testing
- Blue-light filtering intraocular lens, Conventional intraocular lens
- Where
- United States
- Volunteers
- 10,192 people
- Sponsor
- University of Pittsburgh
Cataract
Evaluation of the Rotational Stability
To evaluate rotational stability of the investigational device implanted after cataract surgery.
- Trial name
- NCT03247751
- Testing
- intraocular lens
- Volunteers
- 95 people
- Sponsor
- Nidek Co. LTD.
Cataract, Presbyopia Correction
Photopic and Mesopic Multifocal IOL Performance
Modern cataract surgery has become a refractive procedure. Both, multifocal lens implantation and pseudophakic monovision with monofocal IOLs are effective means to address presbyopia correction after cataract surgery.
- Trial name
- MIOLRead (NCT06978556)
- Testing
- No intervention is subject of the study. Only standard pre- and postoperative data will be evaluated.
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IROC AG
Presbyopia
Functional Assessment of Activities of Daily Living (ADL) in Patients Who Underwent Mini-monovision Correction
Patients who underwent mini-monovision (with bilateral myopic defocus, MM-BMD) surgery for presbyopia correction with monofocal intraocular lenses implantation are supposed to have sufficient uncorrected vision capacity for…
- Trial name
- NCT02431156
- Testing
- Assessment of visual capacity
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Democritus University of Thrace