Clinical trials: Intraocular Pressure
Vision
Safety Study Looking at the Effects of Stendra on Vision
The purpose of this study is to see if Stendra causes any changes in vision, eye pressure, pupil dilation, and color vision in healthy males.
- Trial name
- NCT02033200
- Testing
- Stendra 200 mg
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Glaucoma
Effect of Age on Latanoprost 0.005% in Patients With Glaucoma
Latanoprost is a commonly used treatment for glaucoma. Because of its mechanism of action, it is plausible that the age of a patient using the medication may affect its efficacy and time of onset.
- Trial name
- NCT00224289
- Testing
- Latanoprost 0.005%
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Yale University
Anesthesia
Clonidine Added Lidocaine in Intraocular Pressure and Hemodynamics Ocular in Sub-Tenon's and Peribulbar Anesthesia
Regional anesthesia in orbit can reduce ocular blood flow, increase in intraocular pressure (IOP) or the pharmacological action of local anesthetics.
- Trial name
- NCT02733757
- Testing
- Clonidine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Intraocular Pressure and PROSE Lens
Tonometry Precision and Accuracy During PROSE Scleral Lens Wear: A Pilot Study
The goal of this research is to determine the reproducibility of measurements of intraocular pressure (IOP) when a scleral lens is on the eye.
- Trial name
- NCT04308941
- Testing
- Intraocular pressure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boston Sight
Primary Open Angle Glaucoma, Healthy Subjects
Efficacy of 24-hour Intraocular Pressure Fluctuation Recording With the SENSIMED Triggerfish Contact Lens Sensor
The objectives of this study are to assess the safety and effectiveness of the SENSIMED Triggerfish® (TF) device in continuous recording of relative fluctuation in intraocular pressure (IOP).
- Trial name
- NCT01390779
- Testing
- SENSIMED Triggerfish
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Problem With Vision Blindness, Intraocular Pressure
Intraocular Pressure During Abdominal Aortic Aneurysm (AAA) Repair
The objective of this study will be to answer a clinical question that has not already been investigated; that is, what are the effects of aortic infra-renal clamping and unclamping on intraocular pressure during Abdominal Aortic…
- Conditions
- Problem With Vision Blindness, Intraocular Pressure, Ischemic Optic Neuropathy
- Trial name
- NCT00450294
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Glaucoma, Open Angle Glaucoma
Performance and Safety of the ARGOS-SC Suprachoroidal Pressure Sensor in Patients With Glaucoma Undergoing Non-penetrating Glaucoma Surgery
The purpose of this study is to evaluate both the safety and feasibility of the surgical implantation of the ARGOS-SC implant during non-penetrating glaucoma surgery and the safety and usability of the ARGOS-SC implant and system…
- Trial name
- ARGOS-SC01 (NCT03756662)
- Testing
- ARGOS-SC suprachoroidal pressure sensor
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Implandata Ophthalmic Products GmbH
Intraocular Pressure, Oncology
Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients
Steep Trendelenburg positioning and insufflation of the abdominal cavity have shown to increase intra ocular pressure. Different anesthetic techniques can alter intra ocular pressure and a small pilot study showed decrease in…
- Trial name
- NCT04281017
- Testing
- TIVA, Balanced anesthesia
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florida
Robot-Assisted Laparoscopic Radical Prostatectomy
The Impacts of Surgical Visibility Through Deep Neuromuscular Blockade on Intraocular Pressure in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Intraocular pressure is significantly increase during robot-assisted laparoscopic radical prostatectomy which is performed in a steep trendelenburg position at prolonged times of pneumoperitoneum.
- Trial name
- NCT02109133
- Testing
- deep neuromuscular blockade, moderate neuromuscular blockade, Rocuronium
- Where
- South Korea
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Glaucoma, Sedation
Effect of Nitrous Oxide (N2O) on Intraocular Pressure in Healthy Volunteers
The purpose of this study is to learn if breathing nitrous oxide (also known as "laughing gas") changes the pressure in a person's eyes.
- Trial name
- NCT00967694
- Testing
- Nitrous oxide
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Nail Growth Cessation, Intraocular Pressure
Cutaneous Prostaglandin Application: Nail Growth, Nail Brittleness, and Eye Pressure
Topical prostaglandin agents are used to help reduce eye pressure in glaucoma patients. Bimatoprost (Lumigan 0.01%) is such an agent (Allergan, Inc.).
- Trial name
- NCT02448043
- Testing
- Bimatoprost 0.01%
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Glaucoma, Healthy
Glaucoma Biomarkers
Glaucoma is a major cause of blindness. The inability to predict a patient's IOP response to medications is a critical barrier for the clinician to consistently provide highly effective IOP-based treatments.
- Trial name
- NCT01677507
- Testing
- Variation in eye pressure response to timolol and latanoprost treatment
- Where
- 3 sites in United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Ocular Hypertension
Effect of Alternate Therapies on Intraocular Pressure in Ocular Hypertension
The purpose of this study is to evaluate the effect of complementary and alternative therapies, specifically alternate nostril breathing and foot reflexology, on intraocular pressure in patients with ocular hypertension.
- Trial name
- NCT02993445
- Testing
- Alternate Nostril Breathing, Foot Reflexology
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Temple University
Intraocular Pressure
The Effect of Brimonidine
This study will evaluate whether pre-treating patients with Brimonidine 0.2% before and/or after dilating the pupils will help to control the changes in intraocular pressure often seen when using dilating drops.
- Trial name
- NCT03959176
- Testing
- Brimonidine, Tropicamide, Phenylephrine Ophthalmic Product
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Normal Tension Glaucoma
Intraocular Pressure and Ocular Perfusion Pressure of Cosopt in Normal Tension Glaucoma
To prove the non-inferiority of the fixed timolol-dorzolamide combination (Cosopt) compared to 0.005% latanoprost (Xalatan) in the aspects of intraocular pressure (IOP) and ocular perfusion pressure (OPP) in subjects with normal…
- Trial name
- NCT01175902
- Testing
- dorzolamide/timolol, latanoprost
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Intraocular Pressure
Clinical Study for TONOREF III Tested to ANSI Z80.10-2014
The primary objective of this clinical study was to show that tonometry values for TONOREF III, as the representative device of the NIDEK tonometer series, were comparable to the predicate device.
- Trial name
- NCT07152808
- Testing
- NIDEK TONOREF III, Haag-Streit Goldmann Manual Tonometer
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Glaucoma
The Water Drinking Test in Glaucoma Study
To investigate the correlation and agreement between the intraocular pressure peaks detected during the water drinking test and modified diurnal tension curve in glaucomatous eyes and to analyse whether this is associated with…
- Trial name
- WIGS (NCT05283031)
- Testing
- Modified Diurnal Tension Curve
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Intraocular Pressure
Comparative Study of the NIDEK TONOREF III and the Haag-Streit Goldmann Manual Tonometer and Comparison of Pachymetry Values for NIDEK TONOREF III With the NIDEK CEM-530
The primary objective of this clinical study is to prove that tonometry values for NIDEK TONOREF III are comparable to the predicate device and to prove that the pachymeter function of NIDEK TONOREF III is equivalent to the…
- Trial name
- NCT03441477
- Testing
- Nidek Tonoref III, Haag-Streit Goldmann Manual Tonometer, NIDEK CEM-530
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Primary Open Angle Glaucoma
The Effects of Caffeinated Coffee on Intraocular Pressure
High intraocular pressure (IOP) is a known risk factor for developing primary open-angle glaucoma (POAG). There is controversy in the literature regarding the degree to which caffeine influences IOP, with some studies reporting…
- Trial name
- NCT01364207
- Testing
- Caffeinated Coffee, Decaffeinated Coffee
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Normal-Tension Glaucoma
Pilot Study on Ambulatory Intraocular Pressure and Blood Pressure Monitoring in Glaucoma
Purpose: To study the feasibility of a larger study by determining the tolerability of measuring blood pressure (BP) and intraocular pressure (IOP) over 24 hours in an ambulatory fashion with automatic devices.
- Trial name
- NCT01912599
- Testing
- Sensimed Triggerfish, Blood Pressure
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill