Clinical trials: Intraocular Pressure Changes
Autoregulation
Regulation of Choroidal Blood Flow During Combined Changes in Intraocular Pressure and Arterial Blood Pressure
Autoregulation is the ability of a vascular bed to maintain blood flow despite changes in perfusion pressure. For a long time it had been assumed that the choroid is a strictly passive vascular bed, which shows no autoregulation.
- Trial name
- NCT00812526
- Testing
- Suction cup application, Squatting
- Where
- Austria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Glaucoma, Open-Angle, Ocular Hypertension
Intraocular Pressure With Loteprednol and Dexamethasone
The purpose of this study is to compare intraocular pressure (IOP) changes after pterygium surgery among patients using loteprednol and dexamethasone during the postoperative period.
- Trial name
- NCT00781300
- Testing
- Loteprednol Etabonate 0.5%, Dexamethasone 0.1%
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Glaucoma, Cataract
IOP and Ocular Biometrics Changes After Phacoemulsification in Glaucoma Patients and Controls
Effect of phacoemulsification on intraocular pressure has been studied with variable results.Furthermore, effect of phacoemulsification on ocular biometrics including anterior chamber depth and angle opening distance has also…
- Trial name
- NCT04334473
- Testing
- phacoemulsification and Intraocular lens implantation, Ultrasound Biomicrosopy (UBM)
- Where
- Egypt
- Volunteers
- 37 people
- Sponsor
- Mai Nasser Abd Elmohsen
Intraocular Pressure, Refractive Surgery
Measuring the Changes of the Intraocular Pressure After Corneal Laser Refractive Surgery Using Different Techniques
To evaluate the changes that occur in the intraocular pressure after corneal refractive surgery either PRK , LASIK and femtosecond laser by using Corvis CT results and applanation tonometer
- Trial name
- NCT07549815
- Testing
- Corvis machine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Intraocular Pressure
Intraocular Pressure Change Following Intravitreal Injection of Anti-vascular Endothelial Growth Factor Agent
The introduction of additional fluid into the vitreous cavity by intravitreal therapy would be expected to cause an immediate rise in the intraocular pressure.
- Trial name
- NCT02474225
- Testing
- Intravitreal injection (bevacizumab or ranibizumab)
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Prince of Songkla University
Vascular; Change, Dietary Modification
On-Line Intervention to Lower Cardiovascular Risk in Pediatric Heart Transplant Patients
Pediatric heart transplant patients have a high-risk cardiovascular profile affecting their long-term outcomes and survival. Currently, no effective cardiovascular preventative care is provided for this pediatric population, in…
- Conditions
- Vascular; Change, Dietary Modification, Physical Activity, Health Behavior
- Trial name
- NCT02519946
- Testing
- On-Line Diet and Exercise Intervention
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Stanford University
Intraocular Pressure Changes, Peripheral Anterior Synechiae Increasing
Laser Iridotomy Versus Surgical Iridectomy in Early Angle Closure
This is a randomized controlled clinical trial to compare laser peripheral iridotomy(LPI) and surgical peripheral iridectomy. Subjects of primary angle closure suspect, primary angle closure will be randomized to undergo LPI or…
- Trial name
- NCT01468103
- Testing
- Surgical Iridectomy, Laser Iridotomy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Sun Yat-sen University
Diabetic Macular Edema, Neovascular Age-Related Macular Degeneration
Changes in Intraocular Pressure After Intravitreal Injection
Intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections introduce additional fluid volume into the eye, which can cause an acute, transient elevation in intraocular pressure (IOP).
- Conditions
- Diabetic Macular Edema, Neovascular Age-Related Macular Degeneration, Retinal Vein Occlusion, Ocular Hypertension
- Trial name
- NCT07826286
- Volunteers
- 50 people
- Sponsor
- Assiut University
Vision Disorders, Ocular Surface Disease
Optic Nerve Diameter and Intraocular Pressure Changes in Patients Undergoing Vitrectomy Under General Anesthesia
This study aimed to measure optic nerve sheath changes in the intraoperative period in patients who underwent vitrectomy surgery and to investigate the intraoperative factors that may affect this.
- Trial name
- NCT05195801
- Testing
- USG
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Akdeniz University
Intraocular Pressure Changes, Upper Gastrointestinal Endoscopy
Intraocular Pressure Changes During EGD
This prospective observational study evaluates short-term changes in intraocular pressure (IOP) during elective esophagogastroduodenoscopy (EGD) performed under routine sedation.
- Trial name
- ENDO-IOP (NCT07190508)
- Testing
- No Intervention (Observational)
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Sevim Şenol Karataş
Glaucoma
Change in IOP Fluctuation After DSLT
This is a prospective, single-center, single-arm, observational study designed to evaluate the change in diurnal intraocular pressure (IOP) fluctuation following Direct Selective Laser Trabeculoplasty (DSLT) in patients with…
- Trial name
- NCT07428668
- Testing
- Voyager DSLT
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ophthalmology Associates, Fort Worth
Eye Disease
The DIOXXACT Trial(Diurnal IOP and OBF Xalatan vs Xalatan And Cosopt Trial)
Diurnal and intervisit fluctuations in IOP are strongly associated with progression of open angle glaucoma and therefore need to be minimized.
- Trial name
- DIOXXACT (NCT00957190)
- Testing
- Dorzolamide 20 mg and Timolol 5 mg
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Intraocular Pressure, Intracranial Pressure
Intraocular Pressure and Optic Nerve Sheath Diameter Changes in Laparoscopic Cholecystectomies
Pneumoperitoneum created during laparoscopic surgeries has some effects on human physiology. Increased intraabdominal pressure results in increased intrathoracic pressure, and eventually may result in increased intracranial and…
- Conditions
- Intraocular Pressure, Intracranial Pressure, Pneumoperitoneum
- Trial name
- NCT03933254
- Testing
- Intraocular pressure measurement via ocular tonometry
- Sponsor
- Marmara University
Healthy
Regulation of Optic Nerve Head Blood Flow During Combined Changes in Intraocular Pressure and Arterial Blood Pressure
Autoregulation is defined as the ability of a vascular bed to adapt its vascular resistance to changes in perfusion pressure. In the eye, several studies have reported that retinal blood flow is autoregulated over a wide range of…
- Trial name
- NCT00912665
- Testing
- Laser Doppler Flowmetry, Goldmann applanation tonometer, squatting
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Glaucoma, Pulmonary Hypertension
Changes in Eye Pressure and Anterior Chamber Depth With Oral Endothelin Antagonist Therapy
There is growing evidence that a cause of glaucoma is linked to circulatory problems and poor auto-regulation of blood flow to the optic nerve.
- Trial name
- NCT00452283
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Colorado, Denver
Retina; Change, Intraocular Pressure
Changes After Suprachoroidal Injection.
Changes after suprachoroidal injection are analyzed for statistical analysis.
- Conditions
- Retina; Change, Intraocular Pressure, Cataract, Macular Edema
- Trial name
- NCT05288192
- Testing
- Suprachoroidal triamcinolone acetonide (SCTA) injection
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Benha University
Healthy Volunteers
SENSIMED Triggerfish Sensor Sizes
This is a study investigating the effect of various SENSIMED Triggerfish sensor lens sizes on the recorded IOP related patterns in 10 healthy volunteers.
- Trial name
- NCT01972997
- Testing
- SENSIMED Triggerfish
- Where
- Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Healthy
Choroidal Thickness During Changes in Intraocular Pressure and Arterial Blood Pressure
Age-related macular degeneration (AMD) and glaucoma are among the leading causes of blindness in the western world. Elevated intraocular pressure (IOP) is a well known major risk factor for glaucoma.
- Trial name
- NCT01333891
- Testing
- Phenylephrine, Sodium-Nitroprusside, Suction Cup
- Where
- Austria
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Intraocular Pressure
IOP Changes With Different Anesthetic Agents During Laparoscopic Colorectal Surgery
This study is aimed to evaluate how intraocular pressure (IOP) is changed depending on surgical position (Trendelenburg versus reverse Trendelenburg) in the same patient and to compare the effects of different anesthetics on IOP…
- Trial name
- NCT03016234
- Testing
- Desflurane, Propofol
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Saint Vincent's Hospital, Korea
Spine Surgery, Vision Impairment
Intraocular Pressure During Prone Spinal Surgery
Postoperative visual loss resulting from surgical procedures not performed on the eye is a devastating outcome for the patient and poorly understood by the medical community. It is potentially a preventable complication.
- Trial name
- NCT00176722
- Testing
- table tilt
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- University of Medicine and Dentistry of New Jersey