Clinical trials: Intraoperative Analgesia
Colicystitis
Comparison of the Effectiveness of Intraoperative Intravenous Lidocaine and Intravenous Remifentanil in Postoperative Pain Management in Laparoscopic Cholecystectomy
This study aims to compare the effects of intraoperative intravenous lidocaine and intravenous remifentanil on postoperative pain management in patients undergoing laparoscopic cholecystectomy under general anesthesia.
- Trial name
- NCT07312877
- Testing
- Lidocaine, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Mastectomy, Modified Radical
Intraoperative Pectoral Block vs IV Analgesia for Pain After Modified Radical Mastectomy
There is difference in post operative pain between patients receiving inter- pectoral block and those receiving standard Intravenous analgesia(INJ TORADOL) in patients undergoing Modified Radical Mastectomy.
- Trial name
- NCT07257874
- Testing
- bupivacaine 0.5% injection, Ketorolac 30 mg IV
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Islamabad Medical and Dental College
Analgesia, Nociceptive Pain
Effect of ANI on Intraoperative Opioid Consumption
The aim of the study is to compare the analgesic nociception index (ANI), which is used to determine the dose of analgesic agent needed in the intraoperative period, with the conventional method in patients with erector spinae…
- Conditions
- Analgesia, Nociceptive Pain, Nerve Block, Pain
- Trial name
- NCT05106452
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Spine Surgery, Postoperative Pain Management
Intraoperative Placement of Vancomycin-impregnated Calcium Sulfate Beads Conjugated With Analgesics to Improve Spine Surgery Outcomes
The goal of this clinical trial is to learn if using calcium sulfate beads that contain vancomycin (an antibiotic) and pain-relieving medicines during spine surgery can improve recovery compared to standard care with intravenous…
- Trial name
- NCT07201987
- Testing
- Vancomycin (local, via calcium sulfate beads), Morphine (local, via calcium sulfate beads), Bupivacaine (local, via calcium sulfate beads)
- Volunteers
- 100 people
- Sponsor
- Ganesh M. Shankar
Complication of Anesthesia
Assessing Peripheral Nerve Block Scoring Systems for Intra-Operative and Post-Operative Analgesia
The purpose of this study is to determine if Peripheral Nerve Block scoring systems are effective in predicting the achievement of intra-operative anaesthesia and post-operative analgesia.
- Trial name
- NCT02041806
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- The Adelaide and Meath Hospital
Acute Post Operative Pain, Motor Activity
Compartive Study Between Caudal and Perianal Block During Anal Sphincter Sparing Procedures Under General Anesthesia
Anal fistula is an abnormal tract communicating an external opening in the perianal skin with an internal opening in the anal canal. Anal fistula is treated by fistulotomy .
- Trial name
- NCT05557734
- Testing
- caudal block, perianal block
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University
Pain, Postoperative
Effect of Ketamine on Analgesia Post-Cardiac Surgery
Randomized, controlled, double-blind pilot study evaluating the effect of an intraoperative infusion of intravenous Ketamine on the quantity of opioid consumed postoperatively in coronary artery bypass surgery patients receiving…
- Trial name
- NCT02925858
- Testing
- Normal Saline Flush, 0.9% Injectable Solution_#1, Ketamine Hydrochloride
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Jewish General Hospital
Analgesia
Efficacy and Safety of Erector Spinal Plane Block (ESPB) for Analgesia in Laparoscopic Cholecystectomy
Purpose: to evaluate the efficacy and safety of erector spinal block (ESB) for analgesia in laparoscopic cholecystectomy（LC）. Method: This study is a randomized, single-blind, controlled clinical trial.
- Trial name
- NCT04648345
- Testing
- Erector spinal plane block
- Volunteers
- 90 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Laparoscopic Nissen Fundoplication
Intraoperative Use of Dexketoprofen Trometamol, Pethidine Hcl, Tramadol Hcl and Their Combinations for Postoperative Pain Management in Laparoscopic Nissen Fundoplication
The purpose of this study is to evaluate the analgesic effects of dexketoprofen trometamol, tramadol hydrochloride, pethidine hydrochloride and their combinations in laparoscopic Nissen fundoplication.
- Trial name
- NCT01558622
- Testing
- dexketoprofen trometamol, tramadol hydrochloride, pethidine hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Kavaklıdere Umut Hospital
Pain, Anesthesia
NoL and BIS Monitoring on Patients Recovery and Safety After Surgery
So far, only vital signs (mostly, blood pressure and heart rate) helped the anesthesiologist to administer hypnotic agents or analgesics.
- Trial name
- CINAAMON (NCT03410485)
- Testing
- BIS index/NoL index, Variation of baseline mean arterial pressure
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Erector Spinae Plane Block
Effectiveness of Bilateral Ultrasound-Guided Erector Spinae Plane Block
The proposed mechanism of action of the ESPB is via blockade of the dorsal and ventral rami of the spinal nerves and sympathetic nerve fibers.
- Trial name
- NCT04110210
- Testing
- Bilateral Ultrasound-Guided Erector Spinae Plane Block, Morphine Consumption
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Intraoperative Neurophysiological Monitoring, Pain Management
Effect of a Bolus of Clonidine Systemically Administered on the Excitability of the Spinal Motoneurons of the Lower Extremity
The purpose of this study is to assess the effect of IV clonidine administration on lower limb spinal motoneuron excitability during standardized total intravenous anesthesia (propofol and remifentanil).
- Trial name
- EXCICLON (NCT02592915)
- Testing
- Clonidine hydrochloride, Single bolus of physiologic sodium chloride serum administered IV after induction and obtaining a stable anaesthetic level
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Queen Fabiola Children's University Hospital
Post Operative Pain
Comparison of Intraoperative Intravenous Lidocaine Infusion and Transversus Abdominis Plane (TAP) Block for Post-operative Analgesia Following Laproscopic Cholecystectomy
This study is aimed to determine the post operative pain after laparoscopic cholecystectomy by dividing patients into three different group.
- Trial name
- NCT05231941
- Testing
- Lidocaine IV, Ropivacaine
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Postoperative Pain
Dexamethasone for Post Cesarean Delivery Analgesia
The purpose of this study is to assess the effectiveness intravenous (IV) dexamethasone when used as part of a multimodal regimen to manage post cesarean delivery pain.
- Trial name
- NCT01868633
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Iowa
Laminectomy
Preemptive Analgesia for Postlaminectomy
To relieve post laminectomy pain, we have tried intraoperative perineural injection of lidocaine right after the exposure in expecting that this would be preemptive analgesia by blocking the nerve transmission so that…
- Trial name
- NCT00656526
- Testing
- Lidocaine, perineural injection, intraoperatively, Lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Harran University
Osteoarthritis, Degenerative Joint Disease
Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement
The purpose of this study is to clarify the efficacy of a multidrug versus single drug periarticular injection when only standard operative and postoperative pain management protocols used and the control group is exposed to what…
- Trial name
- NCT03119038
- Testing
- Bupivicaine + epinephrine, Bupivacaine, Ropivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Pain, Postoperative, Tonsillar Hypertrophy
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.
- Conditions
- Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis, Pediatric Sleep Apnea
- Trial name
- OPTIMAL (NCT06576830)
- Testing
- Methadone, Fentanyl/Hydromorphone
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Duke University
Distal Radius Fracture
Randomized Controlled Trial Assessing the Effect of Dexamethasone on Postoperative Function After Distal Radius Fixation
The study is designed to assess the use of intraoperative dexamethasone on postoperative analgesia and stiffness after open reduction and internal fixation of distal radius fractures.
- Trial name
- NCT04889547
- Testing
- Dexamethasone, No dexamethasone
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Anesthesia , Analgesia, Breast Surgery
Intraoperative Music and Propofol Consumption in Breast Surgery
The goal of this study is to find out whether listening to music during surgery can reduce the amount of propofol, an anesthesia medicine, needed in patients having elective breast surgery.
- Trial name
- NCT07687095
- Testing
- Intraoperative Music
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Uludag University
Pain Management, Laparascopic Sleeve Gastrectomy
Ketamine for Shoulder Pain Following Laparoscopic Gastric Sleeve Surgery
Shoulder pain is a well-recognized complaint following laparoscopic surgery. It is underlying mechanism has various causes, therefore, modalities in management and prevention of this sort of pain are numerous with different…
- Trial name
- NCT07429916
- Testing
- Intraoperative ketamine
- Where
- Jordan
- Volunteers
- 50 people
- Sponsor
- King Abdullah University Hospital