Clinical trials: Intraoperative Care
Hypothermia, Blood Loss,
Comparison of Active and Passive Perioperative Warming Techniques in Reducing Intraoperative Blood Loss
This is a randomized, open label, parallel two arm, clinical study, which compare the Bair Hugger forced-air warming blanket and the conventional warming care practice in China on patients undergoing major surgery to determine…
- Conditions
- Hypothermia, Blood Loss,, Blood Coagulation Disorders
- Trial name
- NCT02214524
- Testing
- Bair Hugger forced air warming system
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Health Care Associated Infection, Hand Hygiene
Reducing Intraoperative Infection Transmission in the Pediatric Operating Room
Patients becoming infected during hospitalization occurs frequently and causes harm. It is important for healthcare facilities to take action to prevent these infections and their spread between patients.
- Trial name
- NCT03992209
- Testing
- Standard care, Protocolized care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Intraoperative Hypotension, Perioperative Care
Machine Learning-Assisted Management of Intraoperative Hypotension for Personalized Treatment
Intraoperative hypotension, defined as a drop in blood pressure during surgery, is a frequent event in patients undergoing general anesthesia.
- Conditions
- Intraoperative Hypotension, Perioperative Care, Hemodynamic Monitoring, Blood Pressure
- Trial name
- HYPOGUARD (NCT07396636)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Nevsehir Public Hospital
ERAS
Preliminary Survey in Preparation for the Implementation of ERAS at Dr Soetomo Hospital
This study aims to analyze the readiness of the team that will support the ERAS application at Regional General Academic Hospital Dr Soetomo.
- Trial name
- NCT05465499
- Testing
- ERAS
- Where
- Indonesia
- Volunteers
- 207 people
- Sponsor
- Dr. Soetomo General Hospital
Abdominal Aortic Aneurism, Abdominal Aortic Rupture
Haemostasis Management of Abdominal Aortic Procedures
Comparative study on efficacy of haemostatic therapy guided either by standard laboratory coagulation parameters or point-of-care testing in patients undergoing vascular surgical procedures.
- Conditions
- Abdominal Aortic Aneurism, Abdominal Aortic Rupture, Perioperative/Postoperative Complications, Surgical Blood Loss
- Trial name
- NCT03426839
- Testing
- Coagulation tests
- Volunteers
- 40 people
- Sponsor
- University of Pecs
Blood Loss, Surgical, Coagulation Disorder
Phase 3 Trial of Reltodecacog Alfa (VMX-C001) vs Usual Pharmacological Care in Patients Taking a FXa Direct Oral Anticoagulant Who Require Urgent Surgery With or Without Heparin.
The goal of this clinical trial is to learn if reltodecacog alfa (VMX-C001) works to to allow blood clotting control in participants who take FXa Direct Oral Anticoagulants (DOACs) during surgery or other invasive procedures that…
- Trial name
- EQUILIBRIX-S (NCT07288489)
- Testing
- Reltodecacog alfa, Usual Pharmacological Care
- Where
- 77 sites in United States, Australia and 16 more
- Volunteers
- 800 people
- Sponsor
- VarmX B.V.
Colorectal Surgery
NIRF Trial: Near-Infrared Spectroscopy for Intraoperative Restriction of Fluids Trial
The purpose of this study is to evaluate if the InSpectra StO2 Monitor can safely guide the amount of fluid needed during colorectal surgery.
- Trial name
- NIRF (NCT00731978)
- Testing
- Restricted intraoperative fluid management
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- Hutchinson Technology Inc
Music Therapy, Anxiety
Therapy on Perioperative Anxiety and Pain in Patients
This study aims to explore the effects of preoperative education combined with intraoperative music therapy on perioperative anxiety and pain in patients undergoing elective cesarean section.
- Conditions
- Music Therapy, Anxiety, Health Education
- Trial name
- NCT06970431
- Testing
- eoperative Education + Intraoperative Music Therapy Arm, Preoperative Education Alone Arm
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Other Complications of Esophagostomy
Outcome Study of Restrictive vs. Liberal Intraoperative Fluid Management Guided by PPV in Esophagectomy
The purpose of this study is to determine whether intraoperative restrictive fluid management guided by pulse pressure variation produces a better effect on the postoperative lung function, kidney function, inflammatory response…
- Trial name
- PPV (NCT01933451)
- Testing
- Intraoperative fluid therapy
- Where
- Taiwan
- Volunteers
- 7 people
- Sponsor
- National Taiwan University Hospital
Breast Augmentation, Pain Management in Postoperative Care
PECS I Block vs. Local Infiltration in Breast Augmentation Pain Management
This study aimed to compare the effectiveness of preoperative PECS I block and intraoperative local anesthetic infiltration in managing postoperative pain following breast augmentation surgery.
- Conditions
- Breast Augmentation, Pain Management in Postoperative Care, Pain Management After Surgery, Pain Management
- Trial name
- NCT06719726
- Testing
- PECS I Block, Local Anesthetic Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yeditepe University Hospital
Blood Loss, Surgical
Point of Care Coagulation Testing in Patients Undergoing Major Surgery
Bleeding is a frequent complication during surgery. The peri-operative administration of blood products, including packed red blood cells, thrombocytes and fresh frozen plasma (FFP), is often deemed necessary.
- Trial name
- POC-OP (NCT00656396)
- Testing
- Coagucheck XS Plus (Point of care monitor of coagulation intraoperative), Control Intervention
- Where
- Switzerland
- Volunteers
- 228 people
- Sponsor
- University of Bern
Aspiration, Respiratory
Continuous Supraglottic pH Monitoring in Prolonged Intubated Intensive Care Patients and High Risk Aspiration Intraoperative Patients
This is a pilot prospective cohort study of the incidence of supraglottic pH readings.
- Trial name
- NCT02604043
- Testing
- pH monitoring, accelerometer monitoring
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Vanderbilt University
Anesthesia
CARE--Childhood Awareness and Recall Evaluation
The purpose of this study is to describe the incidence of recall or awareness under anesthesia in children aged 5-15 by collecting anesthetic and post-operative follow-up data relating to intra-operative recall during general…
- Trial name
- NCT00308984
- Where
- 3 sites in United States
- Volunteers
- 1,784 people
- Sponsor
- Medtronic - MITG
Pain Measurement, Assessment, Pain
Device for Monitoring Pain During Intraoperative, Pre/Post Surgical Periods: Comparison With Standard of Care Monitoring
Study patients are given a hand held device to track pain post surgery.
- Trial name
- NCT02630134
- Testing
- These patients receive the Baeta device and take it home
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Heart Defects, Congenital
NIRS Guidance Trail in Children's Heart Surgery
Heart surgery in young children involves some risks. This study looks at a new type of monitor that may reduce these risks. Near Infrared Reflectance Spectroscopy (NIRS) aims to measure if enough blood reaches vital organs in the…
- Trial name
- NIRS (NCT02157597)
- Testing
- NIRS based management, Control
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Intraoperative Care, Fluid Responsiveness
Short Time Low PEEP Challenge and Mini Fluid Challenge
Optimizing fluid therapy is one of the main concerns for anesthesiologists during the intraoperative period. It becomes even more important in high-risk long lasting surgeries as pancreaticoduodenectomy.
- Trial name
- NCT05419570
- Testing
- Fluid Loading
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Istanbul Saglik Bilimleri University
Nephrectomy / Methods, Intraoperative Hypothermia
Effect of Preoperative Prewarming on Serum Lactate Levels in Patients Undergoing Elective Nephrectomy
The goal of this observational study is to learn whether warming patients before surgery, called "prewarming," affects blood lactate levels (a marker of how well tissues are getting oxygen) and recovery in adults having planned…
- Conditions
- Nephrectomy / Methods, Intraoperative Hypothermia, Hyperlactatemia
- Trial name
- NCT07702487
- Testing
- Preoperative active warming (prewarming)
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Beyzanur Aydoğdu
Perioperative Care, Surgery--Complications
Perioperative Hypothermia and Myocardial Injury After Non-cardiac Surgery
We propose to test the hypothesis that aggressive warming reduces the incidence of major cardiovascular complications, compared to routine care.
- Conditions
- Perioperative Care, Surgery--Complications, Hypothermia; Anesthesia, Myocardial Injury
- Trial name
- PROTECT (NCT03111875)
- Testing
- aggressive warming, routine thermal management
- Where
- 11 sites in United States, China
- Volunteers
- 5,056 people
- Sponsor
- The Cleveland Clinic
Anesthesia, Knee Osteoarthritis
The Assessment of Postoperative Recovery in Elder Diabetic Patients
Total Knee Replacement (TKR) performed under general anesthesia is a common successful orthopedic procedure. Nonetheless, in elder patients with diabetes mellitus (DM) this procedure can present unique challenges to orthopedic…
- Trial name
- TKRDM2013 (NCT01871012)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese PLA General Hospital
Quality of Life
Acupuncture and Integrative Care in Gynecological Surgery
Patients undergoing surgical procedures for gynecological cancer are frequently challenged by intense anxiety prior to surgery, reflecting the accompanying uncertainty regarding the diagnosis, treatment and prognosis of their…
- Trial name
- NCT03560388
- Testing
- Acupuncture and touch/relaxation
- Where
- Israel
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center