Clinical trials: Intraoperative Hypotension
Intraoperative Hypotension, General Anesthesia
Deep Learning Models for Prediction of Intraoperative Hypotension Using Non-invasive Parameters
The investigators aimed to investigate the deep learning model to predict intraoperative hypotension using non-invasive monitoring parameters.
- Trial name
- NCT05762237
- Where
- South Korea
- Volunteers
- 5,175 people
- Sponsor
- Samsung Medical Center
Kidney Transplant, Delayed Graft Function
Effect of Terlipressin for Intraoperative Blood Pressure Management in Kidney Transplantation
Prospective double blind randomized controlled trial. By randomizing patients undergoing kidney transplantation into a conventional catecholamine drug (dobutamine) blood pressure maintenance group and a terlipressin-complexed…
- Conditions
- Kidney Transplant, Delayed Graft Function, Intraoperative Hypotension
- Trial name
- NCT06855758
- Testing
- terlipressin
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Friendship Hospital
Hypotension
Decision Support for Intraoperative Low Blood Pressure
The purpose of this study is to determine whether a decision support system can improve the adherence to thresholds for low blood pressure by anesthesia providers, which in turn prevents their patients from having organ injury.
- Trial name
- NCT02726620
- Testing
- Attending real-time decision support, In-room real-time decision support, Attending feedback emails
- Where
- United States
- Volunteers
- 22,435 people
- Sponsor
- Vanderbilt University Medical Center
Hypotension (MeSH: D007022)
Carotid Artery Blood Flow, Blood Pressure, and Cardiac Output During Anesthesia in Children Aged 0-5 Years
Blood pressure is routinely monitored during anesthesia in children, but blood pressure alone may not accurately reflect blood flow to vital organs.
- Trial name
- CARFLOW (NCT07847203)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Cardiac Surgery, Intraoperative Hemodynamic Instability
Impact of Intraoperative Hemodynamic Instability on Outcomes in Cardiac Surgery
Intraoperative hemodynamic instability (IOHI) is a common occurrence during cardiac surgery and is associated with organ hypoperfusion. However, the specific impact of IOHI on composite adverse outcomes remains unclear.
- Conditions
- Cardiac Surgery, Intraoperative Hemodynamic Instability, Postoperative Complication, Acute Kidney Injury
- Trial name
- NCT07324694
- Where
- Turkey (Türkiye)
- Volunteers
- 351 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Radiography, Interventional
Early Detection of Intra Operative Hypotension (IOH) During the Induction of General Anaesthesia
During general anaesthesia, intraoperative hypotension (IOH), defined as a mean arterial pressure (MAP) drop of more than 20%, is frequent with potential deleterious effects for patients.
- Trial name
- NCT03756935
- Testing
- All monitoring
- Volunteers
- 62 people
- Sponsor
- Hopital Lariboisière
Myocardial Infarction Postoperative, Myocardial Injury
Myocardial Infarction in the Perioperative Setting
Acute myocardial infarction (AMI) is a significant complication following non-cardiac surgery. The investigators sought to evaluate incidence of perioperative AMI, its preoperative and intraoperative risk factors and the outcomes…
- Conditions
- Myocardial Infarction Postoperative, Myocardial Injury, Intraoperative Complications, Intraoperative Hypotension
- Trial name
- MIPS (NCT03837535)
- Testing
- Surgery
- Where
- Sweden
- Volunteers
- 400,742 people
- Sponsor
- Karolinska University Hospital
Serum Lactate Post-pancreatic Duodenectomy
Intra-operative Hypotension and Post-operative Lactate Level After Pancreatic-duodenectomy
Intraoperative hypotension is a frequent occurrence during pancreaticoduodenectomy (PD) and has been associated with impaired tissue perfusion and organ dysfunction.
- Trial name
- HYPOL (NCT07346274)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Clinico Humanitas
Intraoperative Hypotension, Postoperative Pulmonary Complications (PPCs)
PRO STRESS Trial: Proactive Low-Dose Norepinephrine to Reduce Intraoperative Fluid Administration in Patients at High-Risk for Postoperative Pulmonary Complications Undergoing Laparoscopic Abdominal Surgery
Intraoperative hypotension is commonly treated with fluid administration; however, excessive fluid therapy may contribute to postoperative pulmonary complications.
- Conditions
- Intraoperative Hypotension, Postoperative Pulmonary Complications (PPCs), Fluid Over-load
- Trial name
- PRO STRESS (NCT07627360)
- Testing
- Norepinephrine
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Suez Canal University
the Duration and Severity of Intraoperative Hypotension
HPI in Laparoscopic Colorectal Surgery
Using the Hypotension Prediction Index in patients undergoing laparoscopic colorectal surgery, including data from National Taiwan University Hospital and Taipei Veterans General Hospital
- Trial name
- NCT06756672
- Testing
- HPI guidance, No HPI guidance
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Intraoperative Hypotension
Hypotension Decision Assist - Use, Safety and Efficacy
This clinical investigation will investigate whether Hypotension Decision Assist (HDA) is a feasible, safe and effective patient clinical decision support system to enhance an anaesthetist's ability to manage a patient's…
- Trial name
- HDA-USE (NCT05101590)
- Testing
- Monitored by HDA
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Directed Systems Limited
Intraoperative Hypotension
Oscillometric Versus Intraarterial Blood Pressure Monitoring During Robot-Assisted Prostatectomy
The PROST-BP trial is a prospective, single-center, randomized, patient-blinded, non-inferiority trial investigating whether intermittent oscillometric blood pressure monitoring is non-inferior to continuous intraarterial blood…
- Trial name
- PROST-BP (NCT07349186)
- Testing
- Oscillometric blood pressure monitoring, Intraarterial blood pressure monitoring
- Where
- Germany
- Volunteers
- 210 people
- Sponsor
- University of Hamburg-Eppendorf
Hypotension During Surgery, Geriatric Patient
Relationship Between Grip Strength and Intraoperative Hemodynamic Parameters
In geriatric anesthesia, hand grip strength is used as an important biomarker to evaluate the general health status of elderly patients.
- Conditions
- Hypotension During Surgery, Geriatric Patient, Hand Grip Strength
- Trial name
- NCT06679933
- Testing
- Hand grip strength measurament
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Acute Kidney Injury
Preoperative Serum Albumin and Duration of Intraoperative Hypotension on Postoperative Acute Kidney Injury
Acute kidney injury is one of major adverse postoperative complications. research about postoperative acute kidney injury conclude that low preoperative albumin and intraoperative hypotension is associated to postoperative acute…
- Trial name
- NCT03882658
- Where
- China
- Volunteers
- 37,610 people
- Sponsor
- Peking University First Hospital
General Anesthesia, Aged
Remimazolam Versus Midazolam for General Anesthesia Induction in Elderly Patients Undergoing Non-Cardiac Surgery
This prospective observational cohort study evaluates the effectiveness and safety of two benzodiazepine sedatives-remimazolam and midazolam-used for general anesthesia induction in elderly patients (≥65 years) undergoing…
- Conditions
- General Anesthesia, Aged, Intraoperative Hypotension, Anxiety
- Trial name
- NCT07746505
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hypotension, Neonatal Hypotension
Appropriate Dosage of Vasopressor in Neonates and Infants
In this study, the investigators will evaluate cerebral blood flow before and after drug infusion using ultrasound to suggest blood pressure criteria and dosage of ephedrine, a vasopressor, to maintain adequate cerebral blood…
- Conditions
- Hypotension, Neonatal Hypotension, Intraoperative Complications
- Trial name
- NCT06257316
- Testing
- EPHEDrine Hydrochloride 5 mg/ml
- Volunteers
- 132 people
- Sponsor
- Seoul National University Hospital
Hypotension During Surgery
Use of Hypotension Prediction Index to Reduce Intraoperative Hypotension in Major Thoracic Surgery
Intraoperative hypotension is linked to increased incidence of perioperative adverse events such as myocardial and cerebrovascular infarction and acute kidney injury.
- Trial name
- NCT05615168
- Testing
- "Acumen IQ" guided hemodynamic optimization, "Flotrac" guided hemodynamic optimization
- Where
- Croatia
- Volunteers
- 34 people
- Sponsor
- University Hospital Dubrava
Intra-operative Hypotension, Carotid Stenosis
Effect of Blood Pressure on rSO2 in Carotid Endarterectomy (CEA)
Carotid endarterectomy (CEA) is the recommended treatment for symptomatic high degree stenosis of the internal carotid artery (ICA).
- Trial name
- NCT01451294
- Testing
- Administration of phenylephrine, Administration of ephedrine
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- G.J. de Borst
Intraoperative Hypotension
Continuous Versus Bolus Administration of Norepinephrine to Treat Hypotension During Anesthetic Induction
Intraoperative hypotension is common in patients having non-cardiac surgery with general anesthesia and is associated with organ injury and death.
- Trial name
- INDUCT (NCT05940649)
- Testing
- Continuous norepinephrine administration
- Where
- Germany
- Volunteers
- 262 people
- Sponsor
- Kristen Thomsen
Postoperative Delirium (POD), Intraoperative Hypotension
Maintaining Intraoperative Mean Arterial Pressure at 85 mmHg or Higher to Reduce Postoperative Delirium in Older Patients With Arterial Hypertension Having Non-cardiac Surgery
In older patients having surgery, postoperative delirium (an acute disturbance in awareness, attention, or cognition) is common and associated with short-term and long-term morbidity and mortality.
- Trial name
- ASPIRE-85 (NCT07713121)
- Testing
- MAP at 85 mmHg or higher (intervention group), MAP at 65 mmHg or higher (control group)
- Where
- Germany
- Volunteers
- 3,432 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf