Clinical trials: Intraoperative Neurophysiological Monitoring
Thyroid
Low-dose Rocuronium Effect Neural Monitoring in Thyroid Surgery
Intraoperative Neuromonitoring (IONM) was started to be used by surgeons to help prevent laryngeal nerve (RLN) damage during thyroid and parathyroid operations.
- Trial name
- NCT04230915
- Testing
- Intraoperative nerve monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Brainstem Lesion, Surgery
Data Collection and Analysis in Brainstem Surgeries
The hypothesis is that the structural documentation and analysis of the data of demographics, neuroimaging, IONM and clinical outcomes can help to further standardize the use of such equipment for detecting the integrity of the…
- Conditions
- Brainstem Lesion, Surgery, Intraoperative Neurophysiologic Monitoring
- Trial name
- NCT04707053
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Cantonal Hospital of St. Gallen
Recurrent Laryngeal Nerve Injuries
Recurrent Laryngeal Nerve's Motor Function: Sometimes Motor Fibers May Also Be Located in The Posterior Branch
The investigators hypothesized that, sometimes the posterior branch of the recurrent laryngeal nerve may also have motor function.
- Trial name
- NCT02493881
- Testing
- intraoperative neuromonitoring
- Volunteers
- 337 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Spinal Disease, Anesthesia
Influence of Lidocaine Infusion on Motor Evoked Potential Thresholds
The purpose of this study is to determine the effect of lidocaine infusion on intraoperative neuromonitoring in patients undergoing spine surgery.
- Conditions
- Spinal Disease, Anesthesia, Post Operative Pain
- Trial name
- NCT06792474
- Testing
- Lidocaine in Saline, Normal saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Bone Neoplasm, Metastatic Malignant Neoplasm in the Bone
Intraoperative Neuromonitoring of Sacral Reflexes to Predict Post Operative Function in Patients Undergoing Sacrectomy for Pelvic Bone Malignancy or Patients Undergoing Spinal Procedures Without Sacral Root Involvement
This clinical trial tests how well monitoring the sacral reflexes during surgery (intraoperatively) works to predict the post operative function for patients undergoing removal of the lowest part of the spine (sacrectomy) for…
- Trial name
- NCT07707024
- Testing
- Intraoperative Nerve Monitoring, Surgical Procedure, Survey Administration
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- City of Hope Medical Center
Thyroidectomy
Optimal Concentration of Remifentanil for NIM Tube Intubation With Low-dose NMBA
During thyroid surgery, Intraoperative Neuromonitoring (IONM) plays a crucial role in preventing serious complications such as bilateral vocal cord paralysis.
- Trial name
- NCT06162390
- Testing
- Remifentanil
- Where
- South Korea
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Chilgok Hospital
Evaluation of the Role of IONM in Minimally Invasive Parathyroidectomy Performed for Solitary Parathyroid Adenoma
Evaluation of the Role of Intraoperative Neuromonitoring(IONM) in Patients Undergoing Parathyroid Surgery for Solitary Parathyroid Adenoma
Aim: Intraoperative neuromonitoring (IONM) is frequently used in cases of primary hyperparathyroidism (pHPT); however, its role in cases of solitary parathyroid adenoma has not been clearly defined, and differing opinions exist…
- Trial name
- NCT07836335
- Testing
- INTRAOPERATIVE NEUROMONITORING
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Izmir Katip Celebi University
Cardiac Disease, Cognitive Dysfunction
Cerebral Oxygen Saturation Monitoring In Cardiac Surgery (COSMICS)
Neurological dysfunction continues to be one of the complications of considerable concern in patients undergoing cardiac surgery.
- Trial name
- COSMICS (NCT04766554)
- Testing
- Cerebral oximetry monitor (The INVOS® Cerebral/Somatic Oximeter) and protocol-based interventions
- Where
- 2 sites in Brazil
- Volunteers
- 326 people
- Sponsor
- Instituto Nacional de Cardiologia de Laranjeiras
Epilepsy, Temporal Lobe
The Utility of NIOM During LITT for Refractory MTLE
Mesial temporal lobe epilepsy (MTLE) is the most common cause of medication-resistant epilepsy in adults, and MRI-guided laser interstitial thermal therapy is a new approach to its surgical management; however, while LITT…
- Trial name
- NCT02913742
- Testing
- monitoring by depth electrode
- Where
- United States
- Sponsor
- Duke University
Intraoperative Neurophysiological Monitoring, Spine Surgery
Ciprofol and Remimazolam for Intraoperative Neurophysiological Monitoring During Spine Surgery
Intraoperative neurophysiological monitoring, including motor evoked potentials and somatosensory evoked potentials, is commonly used during spine surgery to help detect impending neurological injury.
- Conditions
- Intraoperative Neurophysiological Monitoring, Spine Surgery, Anesthesia
- Trial name
- CIRIONM (NCT07718152)
- Testing
- Ciprofol, Remimazolam
- Volunteers
- 60 people
- Sponsor
- Affiliated 2 Hospital of Nantong University
Intraoperative Monitoring, Spinal Diseases
Intraoperative Monitoring (IOM) Patient Registry
The primary objective of this study is to evaluate the rate of new or worsening neurologic deficits and/or radiculopathy following lumbar or cervical surgery in light of IOM using neurological testing (motor and sensory) in the…
- Trial name
- IOM (NCT02187653)
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- DC2 Healthcare
Humans, Urinary Incontinence
Intraoperative Nerve Monitoring During Robotic-assisted Radical Prostatectomy
The purpose of this study is to evaluate whether the use of intraoperative nerve monitoring during robotic-assisted radical prostatectomy (RARP) can predict and improve post-surgery urinary continence and erectile function.
- Conditions
- Humans, Urinary Incontinence, Male Urogenital Diseases, Prostatectomy
- Trial name
- NCT03721029
- Testing
- Intraoperative nerve monitoring,, standard of care robotic-assisted radical prostatectomy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Chronic Pain, Neuropathic Pain
Intraoperative Neuromonitoring Recording With a Novel SCS Paddle
The purpose of this study is to demonstrate safety and efficacy of a new spinal cord stimulation paddle electrode which is able to target the dorsal horns, dorsal nerve roots, and dorsal columns.
- Conditions
- Chronic Pain, Neuropathic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes
- Trial name
- NCT05045625
- Testing
- HD Study Electrode
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Albany Medical College
Thyroid
Effect of Intraoperative Nerve Monitoring on Voice Quality During Thyroid Surgery
"Effect of intraoperative nerve monitoring on voice quality during thyroid surgery" Thyroidectomy is a quite often surgical procedure applied by both head and neck surgeons and endocrine surgeons.Recent advances in surgical and…
- Trial name
- NCT02509715
- Testing
- Intraoperative nerve monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Monitoring, Physiologic, Intraoperative Neurophysiological Monitoring
Analyzing the Noxious Autonomic Response During Shoulder Arthroscope Surgery
To record the digital data from monitoring instruments (standard patient monitor) containing cardiovascular system information, and from depth-of-anesthesia monitoring modules (Bispectral index, Entropy module, Surgical…
- Conditions
- Monitoring, Physiologic, Intraoperative Neurophysiological Monitoring, Anesthesia and Analgesia, Arthroscopy
- Trial name
- NCT03688529
- Volunteers
- 40 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Intervertebral Disc Degeneration, Intervertebral Disc Displacement
Protection of Autonomic Nervous System During Lower Spine Surgical Procedures: A Safety and Feasibility Study
A safety and feasibility study of free-run and stimulated corporal electromyography (EMG) to assess autonomic neural function during spinal and/or pelvic surgery in women and men.
- Conditions
- Intervertebral Disc Degeneration, Intervertebral Disc Displacement, Spinal Curvatures, Spinal Stenosis
- Trial name
- NCT02873182
- Testing
- Autonomic nervous system monitoring
- Volunteers
- 20 people
- Sponsor
- Stanley Skinner
Nerve Entrapments, Pelvic Pain
Integration of Intraoperative Neuromonitoring Into Decompression Surgery
To describe a novel technique by integrating the intraoperative neurophysiological monitoring (IONM) into laparoscopy to protect pelvic nerves by continuously monitoring when they are at risk during surgery.
- Trial name
- NCT06009640
- Testing
- Intraoperative neurophysiological monitoring with Nicolet Endeavor IOM Machine
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Breast Cancer, Surgery
Intraoperative Neuromonitoring (IONM) and Bipolar Electrocautery (BE) During Axillary Lymph Node Dissection (ALND)
The purpose of this study is to determine whether the implementation of existing neurosurgical techniques of intraoperative neuromonitoring (IONM) and the replacement of monopolar electrocautery with bipolar electrocautery (BE)…
- Trial name
- NCT07528638
- Testing
- IONM procedure
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Cincinnati
Spine Condition
Evaluating MIONM Effectiveness in Predicting Postoperative Neurological Deficits Using Combined Modalities
Objective: This study aimed to integrate findings from spinal and cranial surgeries with existing literature, emphasizing the role of Intraoperative Neurophysiological Monitoring (IONM) in improving surgical outcomes through best…
- Trial name
- MIONM (NCT06712069)
- Testing
- Multimodal Intraoperative Neurophysiologic Monitoring (MIONM)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Recurrent Laryngeal Nerve Injuries
CRANIO-CAUDAL AND LATERAL APPROACH FOR RECURRENT LARYNGEAL NERVE
The recurrent laryngeal nerve (RLN) dissection should be performed cranio-caudally in TOETVA approach.The aim of this study was to compare the cranio-caudal and lateral approach for RLN dissection in regard with the rates of LOS…
- Trial name
- NCT04379804
- Testing
- Lateral approach, Cranio-caudal approach
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Istanbul University