Clinical trials: Intraoperative Pain Control
Chronic Calcific Pancreatitis
Intraoperative Coeliac Plexus Alcohol Neurolysis Along With Frey's Procedure for a Better Pain Relief
To study the effect of Intra operative Coeliac plexus alcohol neurolysis combined with Frey's procedure for effective pain relief in patients with Chronic Calcific Pancreatitis in a single centre setting with a Randomized…
- Trial name
- INFARCT (NCT02735330)
- Testing
- celiac plexus neurolysis using absolute alcohol, Frey's procedure
- Volunteers
- 136 people
- Sponsor
- Madras Medical College
Pain, Postoperative, Opioid Use
Comparison of Postoperative Nociception Between NOL-guided and Standard Intraoperative Analgesia Based on Fentanyl
Pain is defined as an unpleasant sensory and emotional conscious experience, associated with actual or potential tissue damage. Nociception is the sympathetic response to noxious stimuli during unconsciousness.
- Conditions
- Pain, Postoperative, Opioid Use, Nociceptive Pain, Postoperative Pain
- Trial name
- NOLFentanyl (NCT03858621)
- Testing
- fentanyl NOL guided
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Victor Contreras, MSN
Patients Undergoing Total Laparoscopic Hysterectomy
Effect of Intraoperative Nociception Control Based on Analgesia Nociception Index (ANI) Monitoring on Stress Response During Total Laparoscopic Hysterectomy
The "Analgesia Nociception Index" (ANI; MetroDoloris Medical Systems, Lille, France), derived from an electrocardiogram (ECG) trace, has been proposed as a noninvasive guide to analgesia.
- Trial name
- NCT04343638
- Testing
- conventional nociception control, ANI monitor guided nociception control
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Yonsei University
Rotator Cuff Tear Arthropathy, Post Operative Pain
Effect of Radiofrequency of Suprascapular Nerve in Shoulder Reverse Arthroplasty
The purpuse of this study is to asses if the pulsed radiofrecuency of the supraescapular nerve and accesory nerve have the same or superior efectivity controlling the acute postoperative pain than interscalenic braquial plexus…
- Trial name
- NCT05785572
- Testing
- supraescapular nerve radiofrequency, interescalenic braquial plexus
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Hospital Universitario Virgen Macarena
Postoperative Pain
Clinical Effectiveness and Safety of Intraoperative Methadone in Patients Undergoing Laparoscopic Hysterectomy
The role of a single-dose of intraoperative methadone on postoperative pain and opioid consumption in patients undergoing hysterectomy remains scarcely explored.
- Trial name
- NCT03908060
- Testing
- Methadone, Morphine
- Where
- Denmark
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Impacted Mandibular Third Molar
Comparison of Electrocautery and Scalpel Blade Incisions of Impacted Mandibular Third Molars
This randomized controlled trial aims to compare electrocautery and scalpel blade incisions during surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07723326
- Testing
- scalpel blade incision, electrocautery incision
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Riphah International University
Tonsillitis
Suprazygomatic Maxillary Nerve Block in Pediatric Tonsillectomy
Tonsillectomies are among the most common surgical procedures performed in pediatric populations, with more than 14,000 procedures performed annually in Ontario, with more than 80% being performed to treat sleep-disordered…
- Trial name
- NCT07176533
- Testing
- Suprazygomatic maxillary nerve block (SZMN) with bupivacaine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Obstructive Sleep Apnea
Dex as Analgesic Adjuvant in OSA Patients
The purpose of this study is to assess whether intravenous peri-operative Dexmedetomidine reduces opioid requirements and or improves pain control after Uvulopalatopharyngoplasty (UPPP) in patients with obstructive sleep apnea…
- Trial name
- NCT03613558
- Testing
- Dexmedetomidine
- Where
- United States
- Sponsor
- Montefiore Medical Center
Analgesia, Analgesia, Epidural
Postoperative Analgesia in Major Gynecological Cancer Surgeries
The aim of this study is to compare the effectiveness of epidural block or erector spinae plane block applied for postoperative analgesia in gynecological cancer surgeries.
- Conditions
- Analgesia, Analgesia, Epidural, ERAS
- Trial name
- NCT06424938
- Testing
- Patients who underwent epidural block, Patients who underwent erector spina plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Duygu Akyol
Intra-operative Anesthesia and Analgesia Effects
Pediatric Ilioinguinal / Iliohyogogastric Nerve Block
Ilioinguinal / iliohyogogastric nerve blocks; It is frequently used for analgesia and anesthesia in inguinal region surgeons. However, 95% of these surgeons are under general anesthesia.
- Trial name
- NCT02990884
- Testing
- ketamine
- Volunteers
- 60 people
- Sponsor
- Erzincan University
Pain Measurement
Intraoperative Nociception Monitoring with Medstorm, Medasense and Anspec-pro During Total Intravenous Anesthesia
The randomized controlled trial study aims to validate a new pain monitor during general anesthesia by comparing the new ANSPEC-PRO monitor (non-CE marked) with already CE-marked pain monitors (Medstorm and Medasense).
- Trial name
- NCT04986163
- Testing
- Non-invasive analgesia monitoring with ANSPEC-PRO monitor and MEDSTORM monitor, Non-invasive analgesia monitoring with ANSPEC-PRO monitor and MEDASENSE monitor, Non-invasive analgesia monitoring with MEDSTORM monitor and MEDASENSE monitor
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- University Hospital, Ghent
Post Operative Pain, Gynecologic Cancer
Pilot: Intraoperative TAP Block and Post-operative Pain Control for Minimally Invasive Hysterectomy for Endometrial Cancer
Modern postoperative pain management aims to optimizing pain relief while minimizing opiate usage. While opiates are effective for pain relief, they result in common adverse effects such as nausea, constipation, and urinary…
- Trial name
- NCT05763667
- Testing
- Liposomal bupivacaine, Bupivacain
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Tufts Medical Center
Postoperative Analgesia, Intraoperative Analgesia
Comparison of Analgesic Efficacy ESP Block and QLB II in Kidney Transplantation
Renal transplantation is an increasingly common surgery in recent years. Opioid and/or NSAID use is common in postoperative pain management. However, these drugs have many side effects.
- Trial name
- NCT06660953
- Testing
- Erector Spinae Plane Block, Quadratus Lumborum Block (QLB)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Music Therapy, General Anesthesia
Intraoperative Music Therapy in Gynecological Oncology
Background Perioperative anxiety and postoperative pain can impact surgical morbidity. We aimed to evaluate the effect of intraoperative music therapy in the reduction of immediate postoperative pain in patients undergoing…
- Conditions
- Music Therapy, General Anesthesia, Surgery, Pain
- Trial name
- NCT04694508
- Testing
- Headphones (Disok, Alicante, España)
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Analgesia
Opioid Free Anesthesia for Laparoscopic Cholecystectomy
The goal of this interventional study is to check the efficacy of Erector Spinae block as Opioid Free Anesthesia for Laparoscopic Cholecystectomy. Laparoscopic Cholecystectomy is a commonly performed day care procedure.
- Trial name
- NCT06202664
- Testing
- Erector Spinae Block, Opioid Analgesic
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Muhammad Haroon Anwar
Analgesia
Opioid Sparing Analgesia: Dexmedetomidine Versus Lidocaine for Intracranial Surgeries in Children
Perioperative pain control is necessary in children as inadequate treatment may lead to progression of perception of pain and development of chronic pain in the future.
- Trial name
- NCT04535089
- Testing
- Dexmedetomidine injection, Lidocaine Iv
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Atrial Fibrillation, Catheter Ablation
Electroacupuncture Intervention in Catheter Ablation of Atrial Fibrillation
This is a randomized control trial to determine whether electroacupuncture(EA) intervention with Morphine can reduce the intraoperative pain and early post-operative complications in patients undergoing catheter ablation of…
- Trial name
- NCT05575544
- Testing
- Acupuncture plus morphine
- Volunteers
- 200 people
- Sponsor
- Shanghai Chest Hospital
Analgesia, Obstetrical, Coagulation Defect; Postpartum
IV Ketorolac on Platelet Function Post-Cesarean Delivery
Cesarean delivery has become the most common surgical procedure in the US. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to improve the quality of post-cesarean analgesia and markedly reduce opioid consumption.
- Conditions
- Analgesia, Obstetrical, Coagulation Defect; Postpartum, Nonsteroidals (NSAIDs)Toxicity, Postpartum Hemorrhage
- Trial name
- KetoPltAgg (NCT03805607)
- Testing
- Ketorolac Tromethamine 30 MG/ML
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Postoperative Pain, Inguinal Hernia Unilateral
Levobupivacaine and Postoperative Pain Relief
The study analysed direct levobupivacaine instillation in surgical wound and its effectiveness in postoperative pain control. Half participants received 0,5 % levobupivacaine and the other half received 0,9% saline solution
- Trial name
- NCT04869046
- Testing
- Instillation of levobupivacaine in surgical wound
- Where
- 2 sites in Serbia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mother and Child Health Institute of Serbia Dr Vukan Cupic
Postoperative Pain, Acute, Anaesthetic
Analgesic Effect of Intraoperative Intravenous S-Ketamine During Total Knee Arthroplasty Surgery
Severe acute pain after total knee arthroplasty surgery has multiple implications for hospitals and patients, monopolising resources and affecting the quality of life.
- Trial name
- NCT05289050
- Testing
- sodium chloride (NaCl; 0.9%), S-ketamine
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Ling Dong