Clinical trials: Intraoperative Ventilation
Head and Neck Cancer, Obstructive Sleep Apnea
Intraoperative Ansa Cervicalis Nerve (ACN) Stimulation
Recently published data suggest that stimulation of the infrahyoid strap muscles increases pharyngeal patency in patients with obstructive sleep apnea, but the innervation of these muscles by the ansa cervicalis is variable.
- Trial name
- ACS (NCT05650710)
- Testing
- Nerve stimulation using nerve stimulation device and sterile wire electrode.
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Vanderbilt University Medical Center
Pulmonary Atelectasis
Optimizing Intraoperative Mechanical Ventilation Using EIT-titrated PEEP
The purpose of this randomized single center study is to determine the individual PEEP value that produces the best possible compromise of lung collapse and lung hyperdistention.
- Trial name
- NCT02314845
- Testing
- Optimal PEEP, Low PEEP
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Mechanical Ventilation, Postoperative Pulmonary Complications (PPCs)
Intraoperative Driving Pressure and Postoperative Lung Ultrasound Score in Robot-Assisted Radical Prostatectomy
The primary objective of this study is to evaluate the relationship between intraoperative driving pressure and postoperative lung ultrasound scores in patients undergoing robot-assisted laparoscopic radical prostatectomy.
- Conditions
- Mechanical Ventilation, Postoperative Pulmonary Complications (PPCs), Prostatic Neoplams, Driving Pressure
- Trial name
- NCT07610824
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Etlik City Hospital
Temperature Change, Body
Heated Humidification System Breathing Circuit for Maintenance of Body Temperature in Pediatric Patients
Our goal is to evaluate the efficacy of the Westmed system vs the Bair Hugger Blanket.
- Trial name
- ANAPOD (NCT03896867)
- Testing
- Anapod™ Humi-Therm Heated Humidification System Breathing Circuit, Bair Hugger™ Warming Blanket
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Intraoperative Ventilation, Respiratory Mechanics
Peak Airway Pressure and Respiratory Mechanics During PRVC Ventilation in Laparoscopic Surgery
This study aims to evaluate peak airway pressure and respiratory mechanics during pressure-regulated volume control (PRVC) ventilation in patients undergoing elective laparoscopic abdominal surgery.
- Trial name
- NCT07543939
- Testing
- PRVC Ventilation
- Where
- Saudi Arabia
- Volunteers
- 52 people
- Sponsor
- Specialized Medical Center (SMC)
Anesthesia, Peroperative Complication
Protective Ventilation Based on Alveolar Ventilation in Children
Protective ventilation decreased morbidity and mortality in adults' patients and is now a standard of care in intensive care unit and in anesthesiology.
- Trial name
- PROVENTIPED (NCT03901599)
- Testing
- Alveolar ventilation monitoring estimated by the capnographic ventilation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon
Intraoperative Ventilation
A Comparison of Different Ventilation Strategies in Children Using the Proseal™ Laryngeal Mask Airway
The purpose of this research study is to compare difference between breathing by oneself or with the partial help from an anesthesia machine in children under general anesthesia.
- Trial name
- NCT00966433
- Testing
- Spontaneous ventilation, Pressure support Ventilation, Pressure control ventilation
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Wake Forest University Health Sciences
Gastric Emptying, Glucagon-Like Peptide-1 Receptor Agonists
Effect of Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RA) on Gastric Emptying
This study aims to assess the effect of using Glucagon-like peptide-1 receptor agonists (GLP-1) receptor agonists on gastric emptying on surgical patients and whether specific guidelines need to be established for these patients.
- Conditions
- Gastric Emptying, Glucagon-Like Peptide-1 Receptor Agonists, Intermittent Fasting, Intraoperative Complication Due to Anesthesia
- Trial name
- NCT07140289
- Testing
- Ultrasound of gastric contents
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wael Saasouh, MD
Mechanical Ventilation Complication, Surgery
a Bayesian Analysis of Three Randomised Clinical Trials of Intraoperative Ventilation
The investigators designed a protocol for a Bayesian unplanned posthoc analysis using the pooled dataset from three large randomized clinical trials.
- Conditions
- Mechanical Ventilation Complication, Surgery, Pulmonary Complication, Postoperative Complications
- Trial name
- NCT05886387
- Testing
- High PEEP + Recruitment maneuvers, Standard PEEP. Low positive end-expriatory pressure
- Where
- 4 sites in Brazil, Italy and 2 more
- Volunteers
- 3,836 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Anesthesia, Mechanical Ventilation
VC-AF vs FCV in Obese Patients Undergoing Laparoscopic Surgery
Obesity adversely affects respiratory physiology by reducing lung volumes and compliance and increasing airway resistance and alveolar collapse.
- Conditions
- Anesthesia, Mechanical Ventilation, Obesity
- Trial name
- NCT07875530
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Positive-Pressure Respiration/Methods, Esophagus/Physiopathology
Intraoperative PEEP Setting During Laparoscopic Gynecologic Surgery
The creation of pneumoperitoneum during laparoscopic surgery can have significant effects on the respiratory system including decreased respiratory system compliance, decreased vital capacity and functional residual capacity and…
- Conditions
- Positive-Pressure Respiration/Methods, Esophagus/Physiopathology, Pleura/Physiopathology, Gynecologic Surgical Procedures
- Trial name
- NCT03256396
- Testing
- PEEP setting based on esophageal pressure measured
- Where
- Thailand
- Volunteers
- 44 people
- Sponsor
- Mahidol University
Obese
Intraoperative Electrical Impedance Tomography in Obese Patients Undergoing Robotic Assisted Radical Prostatectomy.
The primary objective of our study will be verify a possible improvement in arterial oxygenation in the obese patient undergoing robotic-assisted radical prostatectomy if the ventilation will be guided by electrical impedance…
- Trial name
- NCT04757025
- Testing
- Electrical Impedance Tomography, Peripheral arterial Saturation
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- Regina Elena Cancer Institute
Obesity, Sleep Apnea
Dexmedetomidine for Postoperative Analgesia After Bariatric Surgery
The purpose of this study is to determine if Dexmedetomidine given at the end of surgery will reduce postoperative morphine consumption and improve postoperative quality of recovery as compared to morphine in patients undergoing…
- Conditions
- Obesity, Sleep Apnea, Diabetes, Hypertension
- Trial name
- NCT02213159
- Testing
- Dexmedetomidine, Morphine
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- American University of Beirut Medical Center
Lung Injury, Pulmonary Complication
Intraoperative Mechanical Power and Ventilation-Associated Lung Injury: Assessing Complications
This study investigates the relationship between intraoperative mechanical power and postoperative pulmonary complications in patients undergoing major abdominal surgery.
- Trial name
- NCT06375980
- Testing
- Intraoperative Mechanical Ventilation Strategies
- Where
- Turkey (Türkiye)
- Volunteers
- 207 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Postoperative Pulmonary Complications (PPCs), Feasibility Studies
PROtective Ventilation With FLOW-Controlled Ventilation
The investigators want to investigate in patients undergoing robot-assisted laparoscopic surgery (a minimally invasive procedure) how applicable flow-controlled ventilation is, and whether it might also be safer than the current…
- Conditions
- Postoperative Pulmonary Complications (PPCs), Feasibility Studies, Pilot Study
- Trial name
- PROFLOW (NCT06703814)
- Testing
- Intraoperative flow-controlled ventilation strategy, Intraoperative pressure-controlled ventilation strategy
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cantonal Hospital of St. Gallen
Thoracic Anesthesia, Geriatric Anesthesia
The Effect of Single Lung Ventilation Duration and Intraoperative Brain Oxygenation on Cognitive Function and Postoperative Pain in Geriatric Patients
One lung ventilation (OLV) is commonly used in thoracic surgery. Although the lack of ventilation of the lung in the surgical area (independent lung) during OLV redirects pulmonary blood flow to the dependent lung, shunt…
- Conditions
- Thoracic Anesthesia, Geriatric Anesthesia, One Lung Ventillation (OLV), POCD - Postoperative Cognitive Dysfunction
- Trial name
- NCT07339124
- Testing
- Cognitive Remediation, Pain Medicine
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Respiratory Failure, Acute Respiratory Failure Requiring Reintubation
Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
Intraoperative intravenous fluid management practice varies greatly between anesthesiologists. Postoperative fluid based weight gain is associated with major morbidity.
- Conditions
- Respiratory Failure, Acute Respiratory Failure Requiring Reintubation, Pulmonary Edema, Pneumonia
- Trial name
- NCT02105298
- Where
- United States
- Volunteers
- 104,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Holmium Laser Enucleation of the Prostate, Lung Protective Ventilation
Intraoperative Lung Mechanics Changes During HoLEP Surgery
This study aims to evaluate changes in driving pressure and static lung compliance during HoLEP surgery and to investigate their relationship with surgical and perioperative factors.
- Conditions
- Holmium Laser Enucleation of the Prostate, Lung Protective Ventilation, Driving Pressure
- Trial name
- NCT07607704
- Testing
- HoLEP surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara City Hospital Bilkent
Mechanical Ventilation Complication
Airway Management in Thoracic Anesthesia in Italy
The aim of this study is to evaluate the positioning time and the malpositioning rate of DLTs and BBs, the degree of difficulty perceived in device positioning, the use of bronchoscopy (BRO), and the quality of lung collapse…
- Trial name
- AIRTHOR (NCT02361983)
- Testing
- Double lumen tube, Bronchial blocker
- Where
- Italy
- Volunteers
- 2,225 people
- Sponsor
- Azienda Ospedaliera S. Maria della Misericordia
Breast Cancer, Quality of Life
Effect of Chan-Chuang Qigong With Breathing Meditation on Quality of Life in Patients With Breast Cancer
The aim of this study was to evaluate the effect of the 15 weeks Chan-Chuang qigong program with breathing meditation on quality of life and interoceptive awareness in patients with breast cancer during chemotherapy.
- Conditions
- Breast Cancer, Quality of Life, Intraoperative Awareness
- Trial name
- NCT05385146
- Testing
- qigong
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Ching-I Chang