Clinical trials: Intrauterine Device (IUD)
Prevention of Pregnancy
Comparative Study of the VeraCept Low-Dose Intrauterine Copper Contraceptive vs. the TCu380 Copper IUD
The purpose of this study is to evaluate the safety and effectiveness of the VeraCept Low Dose Intrauterine Copper Contraceptive compared to the standard T shaped copper IUD, the TCu380.
- Trial name
- NCT02167763
- Testing
- VeraCept Intrauterine Copper Contraceptive, TCu380 IUD
- Where
- Dominican Republic
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sebela Women's Health Inc.
Contraception
DIU-QoL. Quality of Life Evaluation in Intrauterine Device Users.
Knowledge about the impact on quality of life of women initiating IUD in the Spanish population at baseline and after 12 months of use.
- Trial name
- DIUQoL (NCT01731132)
- Testing
- Levonorgestrel IUD or Copper IUD
- Where
- Spain
- Volunteers
- 207 people
- Sponsor
- Bayer
Contraception, Mood Change
Stress Hormones and IUDs
Determine what kind of side effects women experience in the first year after they start using an intrauterine device.
- Trial name
- NCT03499379
- Testing
- Mirena, Paraguard
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception
Early vs. Interval Postpartum IUD Insertion
Intrauterine devices (IUDs) are historically placed at a six-week postpartum visit for women who desire intrauterine contraception after delivery.
- Trial name
- EPPIUD (NCT03462758)
- Testing
- IUD
- Where
- 4 sites in United States
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Contraception
Study Assessing the Reduction of Pain Felt During Installation Intra- Uterine Device by Direct Technique
Intrauterine devices (IUDs) are contraceptive methods of long-acting (from 3 to 10 years depending on the model) and among the most effective.
- Trial name
- DIRECTE (NCT02595125)
- Testing
- IUD
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
IUD Insertion Pain, IUD Insertion
Intrauterine Device Insertion Pain Management
The goal of this clinical trial is to learn if use of topical benzocaine prior to the injection of lidocaine is effective in decreasing pain experienced during IUD insertion in patients 18 or older.
- Trial name
- NCT06951191
- Testing
- Benzocaine 20%, Lidocaine 2%, Saline 0.9%
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Pain
Self-administered Intravaginal 2% Lidocaine Gel Prior to Intrauterine Device Insertion in Nulliparous Women
This study is designed to evaluate if self-inserted intravaginal 2% lidocaine gel is effective at decreasing pain during intrauterine device insertion in nulliparous women.
- Trial name
- LIVIIN (NCT01534520)
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Contraception
Misoprostol With Intrauterine Device Insertion
The purpose of this study is to see if using misoprostol (a medication that softens the cervix) before placing an intrauterine device for contraception reduces pain in women who have never delivered a baby.
- Trial name
- NCT00613366
- Testing
- Misoprostol, Magnesium Oxide
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Postpartum Contraception, Reproductive Health
Predictors of PPIUCD Discontinuation at Two Years: A Clinical Study in Pakistan
This prospective cohort study evaluated the continuation rates, complications, and satisfaction associated with postpartum intrauterine contraceptive devices (PPIUCDs) as a long-acting reversible contraception (LARC) method.
- Conditions
- Postpartum Contraception, Reproductive Health, Family Planning
- Trial name
- NCT06766396
- Testing
- Postpartum Intrauterine Contraceptive Device (PPIUCD).
- Where
- Pakistan
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Glucose Homeostasis
Postprandial Glucose Handing in Contraceptive and IUD Users
Goals: The long-term use of hormonal birth control has been shown to effect glucose handling, or blood sugar regulation, and potentially lead to insulin resistance which increases a person's risk for metabolic diseases such as…
- Trial name
- HCPG (NCT07169591)
- Testing
- Oral Glucose Tolerance test (75g 2-hour)
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- McMaster University
Intrauterine Contraceptive Device Complication
A Comparative Study Evaluating Pain Experienced During Intrauterine Device Insertion in Women
The intrauterine device (IUD) is a reversible contraceptive method with good efficacy and long-lasting action. One of the obstacles to IUD insertion, both for healthcare professionals and patients, is the fear of painful…
- Trial name
- DODIU (NCT07437235)
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Rouen
Contraception
A Novel IUD Insertion Technique
A previous trial performed by our research team, in order to reduce the pain associated with intrauterine device insertion, compared the novel technique of IUD insertion under the guidance of the trans-abdominal sonography to the…
- Trial name
- NCT02582268
- Testing
- intrauterine device TCu 380A, Trans-abdominal sonography
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Reproductive Health
RH and Adolescents
This study will create a model of reproductive health services for HIV-positive female adolescents in Asia.
- Trial name
- NCT02713750
- Testing
- reversible contraceptive methods
- Where
- 4 sites in Thailand
- Volunteers
- 77 people
- Sponsor
- The HIV Netherlands Australia Thailand Research Collaboration
Family Planning
Postpartum Family Planning Program in Rwanda
This trial wants to address high unmet need for postpartum family planning (PPFP) in Rwanda. A previous pilot study tested the intervention (informed by formative work with couples/clients, clinic providers, champions, and…
- Trial name
- NCT05056545
- Testing
- C4 Intervention
- Where
- Rwanda
- Volunteers
- 38,220 people
- Sponsor
- Emory University
Pain During Intrauterine Device Insertion, Anxiety
Virtual Reality for Pain Reduction During IUD Insertion
This study aims to evaluate the effectiveness of virtual reality (VR) as a non-pharmacological distraction intervention during intrauterine device (IUD) insertion.
- Trial name
- NCT07648134
- Testing
- Virtual Reality
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
IUD Insertion Complication, Pain, Acute
The Effectiveness of Music on Pain and Anxiety in IUD Insertion
Although intrauterine devices (IUDs) are a highly effective contraceptive method, fear of pain during insertion is one barrier to use.
- Conditions
- IUD Insertion Complication, Pain, Acute, Anxiety Acute
- Trial name
- NCT03828760
- Testing
- Music listening
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- McMaster University
Vaginal Microbial Diversity
Effects of Copper Versus Levonorgestrel Intrauterine Devices on Mucosal Microbiota and Barrier Function Among Young African Women
The goal of this clinical trial is to definitively determine whether copper intrauterine device (IUD) or hormonal intrauterine system (IUS) results in greater vaginal microbial diversity after 1 year in women (n= approximately…
- Trial name
- NCT07627958
- Testing
- Levonorgesterel Intrauterine system (LNG IUS), Copper T Intrauterine device (Cu-IUD)
- Where
- Kenya
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
HIV, Contraception
Impact of Different Contraceptives on the Immune System of HIV Infected Women in Zambia
In this study, 66 HIV-infected women who desire contraception will be randomly assigned to use either an IUD or Depo Provera, and will be followed for six months.
- Conditions
- HIV, Contraception, HIV Infections
- Trial name
- MSRC (NCT00807625)
- Testing
- Depo Provera, Copper T Intrauterine contraception device
- Where
- Zambia
- Volunteers
- 66 people
- Sponsor
- University of Alabama at Birmingham
Abnormal Uterine Bleeding
Evaluation of the Effects of Levonorgestrel-releasing Intrauterine Device and Dydrogestreone on Quality of Life and Sexual Life in Patients With Abnormal Uterine Bleeding.
This study was retrospectively collected from patients who were diagnosed with abnormal uterine bleeding and received oral dydrogesterone therapy for at least six months or who were administered an intrauterine device containing…
- Trial name
- NCT05474703
- Testing
- SF-36 Scores
- Where
- Turkey (Türkiye)
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
IUD Complication
Postpartum Intra-caesarean Intrauterine Device Insertion Using a Novel Technique
The assessment of efficacy and patient safety of immediate postpartum IUD insertion using a novel technique.
- Trial name
- NCT04718337
- Volunteers
- 75 people
- Sponsor
- Assiut University