Clinical trials: Intrauterine Device (IUD)
IUD, Endometrial Biopsy
2.5% Lidocaine/2.5% Prilocaine Cream for IUD Insertion and Endometrial Biopsy
The aim of this study is to determine if 5g of self-administered topical 2.5% lidocaine/2.5% prilocaine cream, reduces pain during IUD insertion and/or endometrial biopsy.
- Trial name
- NCT07768059
- Testing
- 2.5% lidocaine/2.5% prilocaine topical cream, VersaPro Cream Base for Compounding
- Where
- Canada
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Intra-uterine Device Complication
the Effect of Vitamin B 1 on Menstrual Pattern After Insertion of the IUD.
investigate the effect of vitamin B 1 on menstrual bleeding and spotting after insertion of the IUD.
- Trial name
- NCT05971680
- Testing
- VITAMIN B1 500mg, intra-uterine contraceptive device
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Beni-Suef University
Pain
Photobiomodulation on Pain Perception During the Insertion of the T 380 Copper Intrauterine Device (IUD)
Unplanned pregnancy affects up to 65% of women in some regions of Brazil, contributing to unsafe abortions and maternal mortality.
- Trial name
- NCT06984796
- Testing
- Photobiomodulation, Simulation of Photobiomodulation
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Primary Immune Deficiency Diseases
Primitive Immunodeficiency, Intrauterine Devices and Menstrual Hygiene Products
Primary immune deficiency diseases (PIDDs) constitute a large group of genetic disorders of the immune system which associates to varying degrees an increased susceptibility to infections and immuno-pathological manifestations…
- Trial name
- FEMIDIP (NCT06519734)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intrauterine Devices, Cesarean Section
Immediate Postplacental Insertion of IUDs at Time of Cesarean Delivery: A Randomized Clinical Trial
This is a randomized controlled trial among women who deliver by cesarean at UNC Women's Hospital and desire an Intrauterine Device (IUD) for contraception postpartum.
- Trial name
- IUD@CSD (NCT01539759)
- Testing
- Immediate Postplacental Placement of an IUD during cesarean delivery
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of North Carolina, Chapel Hill
IUD
3 mL Inhaled Methoxyflurane for Intrauterine Device (IUD) Insertion
Intrauterine device (IUD) insertion is a common contraceptive procedure often associated with moderate to severe pain, particularly among nulliparous individuals.
- Trial name
- NCT07295054
- Testing
- Methoxyflurane, Saline
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Women's College Hospital
Contraception
Use Sonography in Patients With Intrauterine Device Presenting With Bleeding
Intrauterine contraceptive device is one of the most efficient and reversible methods of birth control with low cost and long duration of use However, in the first year after insertion, between 5 and 15% of women will have their…
- Trial name
- NCT03140800
- Testing
- intrauterine device
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intrauterine Device Migration
Intrauterine Device Insertion and Felt Pain
The aim of this study is to compare the pain score between the direct method and the conventional method in patients who have undergone copper or hormonal intrauterine devices (IUD) for contraception and to find an answer to the…
- Trial name
- NCT05956184
- Testing
- Intrauterine Device Insertion
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Anxiety, Pain
Investigating Pre-Procedural Anxiety and Effect of Analgesia on Intrauterine Device Placement and Endometrial Biopsy
The purpose of this study is to evaluate pre-procedural anxiety and patient pain perception with IUD insertion/ EMB procedure when using analgesia versus no analgesia by the end of the study and to evaluate the effect of age…
- Trial name
- NCT07031206
- Testing
- Paracervical block- Lidocaine without epinephrine, Benzocaine Gel applied to the cervix, Hydroxyzine Hydrochloride
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pain Due to Intrauterine Contraceptive Device
Pain Control for Intrauterine Device Placement Using Paracervical Block
Intrauterine device (IUD) placement can be painful for patients during and after the procedure. Fear of pain from IUD insertion can be a barrier to obtaining this highly effective long acting reversible contraception.
- Trial name
- NCT02219308
- Testing
- Paracervical Block (PCB)
- Where
- 2 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Contraceptive; Complications, Intrauterine
Surveillance Study of the Contraceptive Intrauterine Device UT380®
The study is a long term Post Market Surveillance Study involving women who will received UT 380® device as a contraceptive method.
- Trial name
- CCDDIUUT (NCT03642171)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Quanta Medical
Intrauterine Device
Intrauterine Device Insertion: a Step for High Satisfaction
The intrauterine device is a safe, reliable and long-acting reversible contraceptive method. Instrumentation of lower genital mucosa during intrauterine device application provokes pain because it is highly sensitive to touch.
- Trial name
- NCT03383432
- Testing
- Intrauterine device, Ultrasound, uterine sounding sparing technique
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Assiut University
Contraception
Effectiveness of Prolonged Use of IUD/Implant for Contraception
This study will evaluate LNG-IUD and Etonogestrel (ENG) Implant users who are willing to use their contraception beyond the end of the FDA-approved duration.
- Trial name
- EPIC (NCT02267616)
- Testing
- Etonogestrel Implant
- Where
- 2 sites in United States
- Volunteers
- 1,076 people, healthy volunteers welcome
- Sponsor
- Indiana University
Contraception, Unintended Pregnancy
Innovative Model of Patient-Centered ConTraception
This study is testing models of contraceptive care that were developed as part of the Contraceptive CHOICE Project. CHOICE is a prospective cohort study of 9,256 women designed to: 1) promote the use of long-acting reversible…
- Trial name
- IMPACCT (NCT02364037)
- Testing
- CHOICE Project Structured Contraceptive Counseling, Contraceptive Education Session, Cost Support for IUDs and implants
- Where
- 3 sites in United States
- Volunteers
- 1,008 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Contraception
Cervical Lidocaine-Prilocaine Cream vs Glyceryl Trinitrate Cream in Nulliparous Women With LNG-IUD Insertion
the aim of the present study is to compare safety and efficacy of cervical Lidocaine-Prilocaine cream versus glyceryl trinitrate cream on pain perception during levonorgestrel- intrauterine device insertion among nulliparous…
- Trial name
- NCT04355598
- Testing
- Lidocaine-Prilocaine cream, glyceryl trinitrate cream
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cervical Pain, Pelvic Pain
The Effect of Nitroprusside on Intrauterine Device (IUD) Insertion
Increasing accessibility of long-acting reversible contraceptive methods, like intrauterine devices (IUDs), is an important strategy to reduce the risk of unintended pregnancy.
- Trial name
- NCT01248091
- Testing
- Nitroprusside Gel
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
IUD
Use of Cervical Cap and Menstrual Disc for Application of Topical Anesthetic Prior to IUD Insertion
This prospective, open label, double arm, feasibility group study will recruit participants planning to undergo office intrauterine device (IUD) placement without sedation or anxiolysis at the Center for Women's Health.
- Trial name
- NCT06891794
- Testing
- Menstrual disc with EMLA cream, Cervical cap with EMLA cream
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Oregon Health and Science University
IUCD Complication
Vaginal Misoprostol and Dinoprostone Prior to Copper Intrauterine Device Insertion in Women
To compare the effect of vaginal dinoprostone versus vaginal misoprostol administered before the copper intrauterine device(IUD) insertion in reducing IUD insertion pain and the difficulty in inserting the IUD in multiparous…
- Trial name
- NCT04505917
- Testing
- dinoprostol, misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital
Pain
The Analgesic Efficacy of Forced Coughing During Intrauterine Device Insertion
This was a randomized controlled trial of 400 women who attended the outpatient clinic of Menoufia University Hospital for copper IUD insertion.
- Trial name
- NCT04602897
- Testing
- forced coughing
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Contraception
Misoprostol Prior to Intrauterine Device (IUD) Insertion in Nulliparous Women
Because of misoprostol's known ability to cause cervical dilation, some family planning providers give their patients a dose of this drug prior to insertion.
- Trial name
- miso (NCT01147497)
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Emory University