Clinical trials: Intrauterine Device (IUD)
Contraception
Safety and Expulsion of Delayed Versus Immediate Postpartum Intrauterine Device Placement
This is randomized controlled trial designed for pregnant women who deliver vaginally at the University of Louisville Hospital and desire to have an intrauterine device (IUD) inserted for postpartum contraception.
- Trial name
- IUD (NCT01598662)
- Testing
- Mirena (levonorgestrel-releasing intrauterine system)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Pain Associated With Intrauterine Device Insertion
LI4 Acupuncture for Pain During Intrauterine Device Insertion
This study will evaluate whether acupuncture can reduce pain during intrauterine device (IUD) insertion. Women undergoing IUD insertion will be randomly assigned to receive either real acupuncture at the LI4 point on both hands…
- Trial name
- NCT07854015
- Testing
- LI4 Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Contraception
Evaluation of a Novel and Simplified Technique for Intrauterine Contraceptive Devices Insertion: a Prospective Cohort Study
The intrauterine devices (IUDs) are a safe, reliable, long-acting and reversible contraceptive method. It is also sound safe and cheap contraceptive methods available and is nearly maintenance free for up to 10 years.
- Trial name
- NCT02841826
- Testing
- IUD, Uterine sounding, Transvaginal ultrasound
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Contraception
Safety and Efficacy of the Effect of Isosorbide Mononitrate in Reducing Pain During Levonorgestrel-releasing Intrauterine Device Insertion
the aim of the study is to evaluate the safety and efficacy of isosorbide mononitrate vaginal administration in reducing pain during LNG-IUD insertion in adolescents and young women
- Trial name
- NCT04311658
- Testing
- Isosorbide Mononitrate 40 MG
- Volunteers
- 88 people
- Sponsor
- Cairo University
Endometriosis
IUD and Norethindrone Acetate for Treatment of Endometriosis
Endometriosis is the most common reproductive disease afflicting young women, often leading to debilitating chronic pelvic pain and impaired quality of life.
- Trial name
- NCT04948489
- Testing
- norethindrone acetate (NETA)
- Where
- United States
- Sponsor
- Boston Children's Hospital
Asherman's Syndrome
Reproductive Outcome Affected by Two Adjunctive Treatments in Patients With Severe Intrauterine Adhesions
The purpose of this study is to compare the outcome of loop intrauterine contraceptive device and heart-shaped intrauterine balloon for the adjunctive treatment of severe intrauterine adhesions in patients with infertility.
- Trial name
- ROABTIPWSIUA (NCT02708277)
- Testing
- loop-shaped intrauterine contraceptive device, intrauterine balloon (Cook Medical)
- Volunteers
- 93 people
- Sponsor
- Yuqing Chen
Intrauterine Device, Cold Compress
Cold Compress for Pain Associated With Intrauterine Device Insertion
This study will be a prospective randomized controlled trial comparing cold compression to no intervention immediately prior to and during intrauterine device insertion.
- Trial name
- NCT02898831
- Testing
- Cold Compress
- Where
- 2 sites in United States
- Volunteers
- 142 people
- Sponsor
- Virginia Commonwealth University
Contraception
Naproxen for Pain Control With Intrauterine Device Insertion
The purpose of this study is: 1. To evaluate whether 550 mg of naproxen sodium reduces pain scores with IUD insertion on a 0-10cm visual analogue scale compared to placebo (primary outcome). 2.
- Trial name
- NCT02388191
- Testing
- Naproxen sodium
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
IUD Removal
Intrauterine Device (IUD) Self Removal
This pilot research study will teach patients how to self-remove intrauterine contraceptive device (IUD) through an educational video and simulation and evaluate patient perspectives and experiences related to IUD self-removal…
- Trial name
- NCT05191238
- Testing
- IUD self-removal education
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Boston Medical Center
Contraception
Vaginal Misoprostol Before Intrauterine Contraceptive Device Insertion
the current study was conducted to assess efficacy of vaginal misoprostol before IUD insertion following previous insertion failure
- Trial name
- NCT03790371
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Genital Tract Mucosal Immunity, Genital Tract Microflora
Study of Immune Cell Changes in the Genital Tract 2 Months After Initiation of an IUD for Contraception
This pilot study is being performed to investigate the influence that starting contraception with an IUD has on the local immune cell populations and features, with a particular focus on the cells and cell-surface features that…
- Trial name
- CHIC (NCT01240811)
- Testing
- IUD placement, Levonorgestrel IUD, Copper T380A IUD
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sharon Achilles
Endometriosis
Levonorgestrel-releasing Intrauterine System in Patients With Endometriosis
The hemostatic and inflammatory systems may activate each other. Endometriosis is a chronic inflammatory disease affecting 10% of women.
- Trial name
- SIU-LNG (NCT02158845)
- Testing
- LNG-IUS: levonorgestrel intrauterine system, GnRHa: leuprolide
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- University of Sao Paulo
IUD Insertion Complication
Comparison of Vaginal Misoprostol and Dinoprostone Prior to Copper Intrauterine Device Insertion in Nulliparous Women
To compare the effect of vaginal dinoprostone versus vaginal misoprostol administered before the copper intrauterine device(IUD) insertion in reducing IUD inertion pain and the difficulty in inserting the IUD in nulliparous women.
- Trial name
- NCT04080336
- Testing
- Dinoprostone, Misoprostol
- Where
- Egypt
- Volunteers
- 129 people
- Sponsor
- Cairo University
Pregnancy, Ectopic
Occurrence and Trend of Pregnancies Growing Outside the Womb (Ectopic Pregnancy) 2009-2018. A Study on a Defined Group of Persons
In this trial researchers want to learn more about the occurrence of pregnancies growing outside the womb over the last decade (2009-2018) and the potential risk factors associated with pregnancies growing outside the womb.
- Trial name
- NCT03670784
- Testing
- No intervention
- Where
- United States
- Volunteers
- 3,922,877 people
- Sponsor
- Bayer
Contraception
Immediate Versus Delayed Insertion of the Copper Intrauterine Device (IUD) After Medication Abortion
After medication abortion, women may quickly become pregnant again and therefore need an effective birth control method right away. Intrauterine devices (IUDs) are very effective for preventing pregnancy.
- Trial name
- NCT00737178
- Testing
- CuT380A
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Columbia University
Vaginal Infection
Relation Between Internal Vaginal Douching and Vaginal Infections in Intrauterine Contraceptive Device Users
To determine the effect of performing internal vaginal douching on the frequency and severity and type of vaginal infections in IUD users
- Trial name
- NCT03261804
- Testing
- relation between vaginal douching and vaginal infection
- Where
- Egypt
- Volunteers
- 604 people
- Sponsor
- Assiut University
Contraception
Early Postpartum Intrauterine Device (IUD) Placement
Women who have just given birth are at high risk for rapid repeat pregnancy, which can lead to negative consequences during the subsequent pregnancy.
- Trial name
- NCT01594476
- Testing
- Levonorgestrel IUS
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Endometrial Polyps, Retained Products of Conception
Impact of Different Saline Pressures During Hysteroscopy on Visibility, Feasibility and Patients' Discomfort
Hysteroscopy is a minimally invasive diagnostic and therapeutic procedure for various intrauterine conditions. It is performed with an optic device while entering liquid media to the uterus to allow visualization.
- Conditions
- Endometrial Polyps, Retained Products of Conception, Lysis of Intrauterine Adhesions, Removal of Retained Intrauterine Device
- Trial name
- NCT06620978
- Testing
- Low pressure: Operative hysteroscopy without anesthesia with normal Saline medium in low pressure.., High pressure: Operative hysteroscopy without anesthesia with normal Saline medium in High pressure.
- Volunteers
- 100 people
- Sponsor
- Assaf-Harofeh Medical Center
Scar Niche, Myometrial Remodeling
Postplacental Copper Intrauterine Device Versus Postpartum Progesterone-only Pills on Uterine Niche Formation
The purpose of the study is to determine whether immediate postplacental copper T380A intrauterine device insertion increases uterine-niche incidence compared with postpartum progestin-only pills after primary cesarean section .
- Conditions
- Scar Niche, Myometrial Remodeling, Contraceptive Device; Complications, Cesarean Section Complications
- Trial name
- T380A (NCT07264933)
- Testing
- Primary Cesarean Section, immediate postplacental insertion of a copper T380A intrauterine device, progesterone-only pills
- Where
- Egypt
- Volunteers
- 750 people
- Sponsor
- Benha University
Pain
Topical Lidocaine for Pain Control With Intrauterine Device (IUD) Insertion
Intrauterine contraception is a very effective, long term, reversible form of birth control, and is increasingly used in young, nulliparous patients.
- Trial name
- NCT01445756
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison