Clinical trials: Intrauterine Devices
Pain Due to Intrauterine Contraceptive Device
Pain Control for Intrauterine Device Placement Using Paracervical Block
Intrauterine device (IUD) placement can be painful for patients during and after the procedure. Fear of pain from IUD insertion can be a barrier to obtaining this highly effective long acting reversible contraception.
- Trial name
- NCT02219308
- Testing
- Paracervical Block (PCB)
- Where
- 2 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Breast Cancer, Contraception
Breast Cancer and Intrauterine Contraception
The present work seeks an alternative to the copper IUD for contraception in breast cancer patients, evaluating the satisfaction and continuity of the copper and silver IUD, as well as the quality of life, compared to the copper…
- Trial name
- NCT05148910
- Testing
- Silver and copper IUD (TCu380Ag), Copper IUD (TCu380A)
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
Contraception
GyneFix-Viz*: A Study of Serosal-Anchor (SA) Distance
The GyneFix-Viz is a frameless copper intrauterine device (IUD) used for contraception. The GyneFix IUD has been marketed in Europe and Asia for about 10 years.
- Trial name
- GF (NCT01979835)
- Testing
- GyneFix Viz
- Where
- Canada
- Volunteers
- 1,030 people, healthy volunteers welcome
- Sponsor
- Wiebe, Ellen, M.D.
IUCD Complication
Vaginal Misoprostol and Dinoprostone and Isonicotinic Acid Hydrazide Prior to Copper Intrauterine Device Insertion
To compare the effect of vaginal dinoprostone versus vaginal misoprostol and Isonicotinic Acid Hydrazide administered before the copper intrauterine device(IUD) insertion in reducing IUD inertion pain and the difficulty in…
- Trial name
- NCT04505943
- Testing
- Isonicotinic Acid Hydrazide, dinoprostine, misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital
Postoperative Adhesion of Uterus
Pivotal Clinical Study to Assess the Anti-adhesive Effect and Safety of ABT13107 Applied to Postoperative Intrauterine
This study is intended to evaluate the efficacy and safety of ABT13107 compared to Hyalobarrier applied to postoperative intrauterine.
- Trial name
- NCT04007211
- Testing
- ABT13107, Hyalobarrier
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Medy-Tox
Contraception
HR-QoL and Sexuality in Mirena Inserted Contraception Users
The purpose of this study is to evaluate the changes in the quality of life, as well as in the sexual activity, in women inserted with MIRENA, a hormonal contraceptive intra-uterine system, over the first 12 months of use.
- Trial name
- NCT00498784
- Testing
- Mirena
- Where
- France
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Bayer
IUD Insertion Pain
Celecoxib Versus Hyoscine Butyl-bromide in Reducing Pain Associated With IUD.
Many oral analgesic drugs such as the nonsteroidal anti-inflammatory drug (NSAID) are used to relieve pain from gynaecological procedures and dysmenorrhea.
- Trial name
- NCT03499743
- Testing
- hyoscine butyl bromide, Celecoxib 200mg
- Where
- Egypt
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Cairo University
IUD Insertion Pain
the Effect of Isosorbide Mononitrate in Reducing Pain During Cooper Intrauterine Device Insertion
The aim of the study is to evaluate the efficacy of isosorbide mononitrate vaginal administration in reducing pain during copper IUD insertion in nulliparous women
- Trial name
- NCT04312048
- Testing
- Isosorbide mononitrate
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Cairo University
Pain Relief
Lidocaine In-situ Gel Before Intrauterine Device Insertion
Intrauterine device can cause pain and discomfort in several ways: Use of the tenaculum to grasp the cervix and straighten the uterus for proper insertion; trans-cervical actions including measuring uterine depth, inserting the…
- Trial name
- NCT02943135
- Testing
- lidocaine in-situ gel
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Birth Control
The Effect of Birth Control Methods on Anti-Mullerian Hormone (AMH) Levels
Anti-mullerian hormone (AMH) has been shown to be a reliable marker of ovarian reserve. In prior studies, tubal ligation has been shown to have an adverse effect on ovarian reserve.
- Trial name
- NCT01308931
- Where
- 3 sites in United States
- Sponsor
- Valleywise Health
HIV, Immune Cells (Mucosal and Systemic)
Quantification of Immune Cells in Women Using Contraception (CHIC II)
This study is being done to understand if using birth control causes changes in the immune cells within the reproductive tract (including the cervix and the lining of the uterus) of healthy women.
- Conditions
- HIV, Immune Cells (Mucosal and Systemic), Contraception
- Trial name
- CHIC-II (NCT01873170)
- Testing
- levonorgestrel exposure, DMPA exposure, etonogestrel exposure
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Contraception
Immediate Postplacental IUD Insertion
The study will be a randomized clinical trial. Women with less than 10 prenatal visits and/or 2 or more no show visits who desire an Intrauterine Device (IUD) will be considered for enrollment.
- Trial name
- NCT02169869
- Testing
- Mirena, Paragard
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Oregon Health and Science University
Pain Relief
Comparison Between 2 Doses of Misoprostol Before Intrauterine Device
The purpose of the investigators' study was to evaluate whether misoprostol will improve pain scores .
- Trial name
- NCT02901561
- Testing
- misoprostol 200, misoprostol 400
- Where
- Egypt
- Volunteers
- 212 people
- Sponsor
- Assiut University
IUD Insertion
Comparison of Pain Level During Intrauterine Device (IUD) Insertion Between Conventional and Direct Method
The so-called "direct" method of intrauterine device (IUD) and intraintuerine system (IUS) insertion is increasingly used. A study has shown that it is technically simpler and assumes less painful than the classic pose.
- Trial name
- KIDDS (NCT03473717)
- Testing
- classic method, direct method
- Where
- 10 sites in France
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intrauterine Devices, Copper, Metrorrhagia
Tracking IUD Bleeding Experiences: An Evaluation of Bleeding Profiles in New Intrauterine Device Users
This study aims to use validated tools as well as new technology to examine changes in bleeding patterns among women who are initiating the copper T380A IUD.
- Conditions
- Intrauterine Devices, Copper, Metrorrhagia, Menstruation, Menstrual Cycle
- Trial name
- TRIBE (NCT02311478)
- Testing
- T380A Intrauterine Copper Contraceptive
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of Utah
Unplanned Pregnancy
A Pilot Study of Early Postpartum Intrauterine Contraception
This is a prospective clinical trial of ultrasound guided intrauterine contraception insertion 10 minutes - 48 hours after vaginal delivery of single infant.
- Trial name
- ImmPPIUD (NCT00997932)
- Testing
- Levonorgestrel-Releasing Intrauterine Contraceptive System (LNG-IUS), 52 Mg, 5 Year Duration
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Contraception
Safety and Expulsion of Delayed Versus Immediate Postpartum Intrauterine Device Placement
This is randomized controlled trial designed for pregnant women who deliver vaginally at the University of Louisville Hospital and desire to have an intrauterine device (IUD) inserted for postpartum contraception.
- Trial name
- IUD (NCT01598662)
- Testing
- Mirena (levonorgestrel-releasing intrauterine system)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Louisville
IUD Insertion Pain
Oral Ketorolac for IUD Pain Reduction
To determine if oral ketorolac given at different timepoints prior to intrauterine device (IUD) insertion influences pain experienced during this procedure.
- Trial name
- NCT06853327
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pain
Intracervical Lidocaine Gel for IUD Insertional Pain
The intrauterine device (IUD) is a form of birth control that is extremely effective and safe, even in women who have not yet had children.
- Trial name
- NCT01214161
- Testing
- 2% lidocaine gel
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Columbia University
Healthy
Intrauterine Embryo Development With ANECOVA Device
We aim to compare the morphological and chromosomal features of human embryos cultured In Vitro versus those developed in a new In Vivo culture system with encapsulation in utero as well as implantation and pregnancy rate.
- Trial name
- ANECOVA (NCT00480103)
- Testing
- in vivo (ANECOVA D-1) or in vitro culture in 25-µl droplets of cleavage medium (Medicult®) under paraffin oil
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA