Clinical trials: Intrauterine Fetal Demise
Fetal Growth Restriction (FGR), Placental Insufficiency
Placental Imaging Techniques
The goal of this proof-of-concept, case-control, clinical trial is to evaluate the efficacy of using two newer ultrasound technologies, quantitative ultrasound (QUS) and ultrafast power Doppler imaging (uPDI), to evaluate the…
- Conditions
- Fetal Growth Restriction (FGR), Placental Insufficiency, Preeclampsia, Still Births
- Trial name
- NCT06861309
- Testing
- ultrafast power Doppler imaging (uPDI) / quantitative ultrasound (QUS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Carilion Clinic
Unexplained Stillbirth
Low Molecular Weight Heparin in Pregnancies With Unexplained Stillbirths
Bemiparin for pregnant women with abnormal umbilical artery Doppler ultrasound
- Trial name
- NCT03601338
- Testing
- Bemiparin, multivitamins and routine antenatal follow up
- Where
- Iraq
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Pain, Breastfeeding
Kinesio Taping Application After Cesarean Section
The study was planned in a randomized controlled study design to determine the effect of kinesio taping applied to women who gave birth by cesarean section on acute pain, comfort level and breastfeeding behavior.
- Conditions
- Pain, Breastfeeding, Caesarean Section;Stillbirth
- Trial name
- NCT05213975
- Testing
- Kinesio tape
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Stillbirth and Fetal Death, Miscarriages
Parents' Experience of Child Loss During Pregnancy or Birth
The investigators are conducting a participatory study with and for parents after child loss during pregnancy or birth. Their aim is to develop treatment recommendations for healthcare professional.
- Conditions
- Stillbirth and Fetal Death, Miscarriages, Experience
- Trial name
- NCT06771661
- Testing
- Workshops, Focus group interviews, Narrative interviews
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- Fritz Sterr
Stillbirth and Fetal Death, Termination of Pregnancy
A Feasibility Study of Virtopsy With Tissue Sampling in Besancon University Hospital
The aim of this project is to assess the feasibility of a new local post mortem procedure at Besançon University Hospital : Virtopsy+, magnetic resonance (MR) imaging with tissue sampling of the fetus and newborns.
- Conditions
- Stillbirth and Fetal Death, Termination of Pregnancy, Neonatal Death
- Trial name
- VIRTOPSY+ (NCT03877900)
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Stillbirth, Delivery Complication
The PartoMa Project: Enabling Best Post Possible Childbirth Care in Tanzania.
Introduction Childbirth care remains suboptimal in many low-resource settings, causing unacceptable maternal and perinatal mortality and morbidity.
- Conditions
- Stillbirth, Delivery Complication, Delivery Delayed, Apgar; 4-7 at 1 Minute
- Trial name
- NCT04685668
- Testing
- The PartoMa guidelines and training
- Where
- Tanzania
- Volunteers
- 65,181 people
- Sponsor
- University of Copenhagen
Pregnancy, Pregnancy Complications
AI-POCUS for Maternal and Neonatal Health in Ethiopia
Maternal and neonatal health remains one of the most pressing global health challenges, particularly in low- and middle-income countries (LMICs).
- Conditions
- Pregnancy, Pregnancy Complications, Preterm Birth, Fetal Growth Restriction
- Trial name
- AIM-ETH (NCT07171086)
- Testing
- AI-POCUS (BabyChecker, Delft Imaging), AI-POCUS (Edan, China)
- Where
- Ethiopia
- Volunteers
- 1,059 people, healthy volunteers welcome
- Sponsor
- Tsinghua University
Postpartum Complication, Caesarean Section;Stillbirth
The Effect of Simulation-based Breastfeeding Education on Breastfeeding Self-efficacy and Breastfeeding Problems
In the literature, there are studies conducted to determine the effect of simulation-based and different training techniques models given in the prenatal period on postpartum breastfeeding self-efficacy.
- Trial name
- NCT06081374
- Testing
- simulation implication
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Labor Induction
A Randomized Trial of Two Regimens of Misoprostol for Second Trimester Termination for Intrauterine Fetal Death
Misoprostol (Cytotec®) is a synthetic prostaglandin E1 analog that has been marketed in the United States since 1988 as a gastric cytoprotective agent.
- Trial name
- NCT00141895
- Testing
- Misoprostol
- Where
- Lebanon
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Small for Gestational Age at Delivery, Hypoxic-Ischemic Encephalopathy
Umbilical Cord Abnormalities in the Prediction of Adverse Pregnancy Outcomes
The objective of our study is to investigate the association of umbilical cord abnormalities with adverse pregnancy outcomes. The umbilical cord parameters that will be investigated as part of this study include the umbilical…
- Conditions
- Small for Gestational Age at Delivery, Hypoxic-Ischemic Encephalopathy, Stillbirth, Admission to Neonatal Unit
- Trial name
- ULOOP (NCT05901688)
- Testing
- Umbilical cord measurements & observations
- Where
- United Kingdom
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Medway NHS Foundation Trust
Perinatal and Neonatal Outcomes in Pregnancies With Type 2 Diabetes Mellitus (T2DM)
Antenatal Myo-inositol Supplementation in Pre-existing Diabetes
This feasibility pilot study aims to gather data that can guide the design of a larger, more comprehensive trial to establish the effects of myo-inositol supplementation on supporting healthy outcomes in pregnancies complicated…
- Trial name
- AMulet (NCT07241221)
- Testing
- Myo-inositol and folic acid supplement, Folic acid supplement
- Where
- Singapore
- Volunteers
- 182 people
- Sponsor
- National University Hospital, Singapore
Stillbirth
Revealed Versus Concealed Cerebroplacental Ratio
The purpose of this study is to evaluate the role of an integrated strategy at selecting fetuses for delivery at term based on a combination of fetal biometry and cerebroplacental ratio (CPR) to reduce stillbirth rate and adverse…
- Trial name
- NCT02907242
- Testing
- Revealment
- Where
- 9 sites in Chile, Czechia and 4 more
- Volunteers
- 11,582 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Perinatal Mortality
Global Network Implementation of Helping Babies Breathe (HBB)
The primary purpose of this pre-post evaluation is to test the impact on perinatal mortality (fresh stillbirths or early neonatal deaths) among births > 1500g of training birth attendants at health facilities in the Helping…
- Trial name
- NCT01681017
- Testing
- HBB/ENC Training and Equipment, HBB/ENC supplies
- Where
- 3 sites in India, Kenya
- Volunteers
- 70,704 people
- Sponsor
- NICHD Global Network for Women's and Children's Health
Abortion, Stillbirth
Perioperative Dexmedetomidine to Reduce Post-procedure Grief Following Second-trimester Dilation and Evacuation
People seeking second-trimester dilation and evacuation (D\&E) procedures are often facing profoundly challenging circumstances, including desired pregnancies complicated by fetal anomalies or demise, serious maternal health…
- Conditions
- Abortion, Stillbirth, PTSD (Childbirth-Related), Grief (Traumatic Grief and Existential Grief)
- Trial name
- NCT07537894
- Testing
- Dexmedetomidine (IV) 0.5 mcg/kg
- Where
- United States
- Sponsor
- Stanford University
Stillbirth, Neonatal Respiratory Depression
Newborn Heart Rate as a Catalyst for Improved Survival
Heart rate (HR) is not routinely assessed during newborn resuscitations in low- and lower-middle income countries (LMICs). Many non-breathing newborns classified as fresh stillbirths have a heartbeat and are live born.
- Conditions
- Stillbirth, Neonatal Respiratory Depression, Neonatal Bradycardia, Neonatal Resuscitation
- Trial name
- NCT03799861
- Testing
- Epoch 2: HBB with NeoBeat, Epoch 3: HR-guided HBB
- Where
- 3 sites in Democratic Republic of the Congo
- Volunteers
- 24,034 people, healthy volunteers welcome
- Sponsor
- American Academy of Pediatrics
Caesarean Section;Stillbirth, Microbial Colonization
Lactobacillus Kefiri LKF01 (DSM32079) in Newborns Born by Caesarian Section
The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants' life.
- Trial name
- NCT03154866
- Testing
- Lactobacillus kefiri LKF01 DSM32079
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Fetal Growth Retardation, Stillbirth
Prediction of Late Fetal Growth Restriction Using Cerebroplacental Ratio
To investigate the screening performance of CPR and biophysical profile score for the prediction of composite of adverse neonatal morbidity and mortality and operative delivery (CS or instrumental) for intrapartum fetal distress…
- Conditions
- Fetal Growth Retardation, Stillbirth, Neonatal Respiratory Failure, Neonatal Death
- Trial name
- NCT04640467
- Testing
- Biophsical profile, Cerebroplacental ratio
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Anxiety State
COVID-19-associated Anxiety of Pregnant Women for Anomalies, Stillbirth and Preterm Labor
Capture of anxiety for anomalies, stillbirth and preterm Labor of pregnant women during COVID-19 pandemia
- Trial name
- CAASP (NCT04568551)
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Stillbirths and Infant Mortality
Oral Azithromycin to Prevent Stillbirths and Infant Mortality in Mali
The double blind randomized controlled trial will assess the efficacy of oral azithromycin administered to pregnant women and/or infants during routine care in preventing stillbirths and mortality through 6-12 months of age in…
- Trial name
- SANTE (NCT03909737)
- Testing
- Azithromycin to pregnant women, Azithromycin to infants, No intervention to pregnant women
- Where
- Mali
- Volunteers
- 99,700 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Decreased Fetal Movements Affecting Care of Mother, Pregnancy
Promoting Awareness Fetal Movements to Reduce Fetal Mortality Stillbirth, a Stepped Wedge Cluster Randomised Trial.
Rates of stillbirth in Scotland are among the highest in resource rich countries. The majority of stillbirths occur in normally formed infants, with (retrospective) evidence of placental insufficiency being the commonest clinical…
- Conditions
- Decreased Fetal Movements Affecting Care of Mother, Pregnancy, Stillbirth
- Trial name
- AFFIRM (NCT01777022)
- Testing
- A package of interventions
- Where
- 29 sites in Ireland, United Kingdom
- Volunteers
- 430,830 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh