Clinical trials: Intrauterine Fetal Demise
Pregnancy Complications, Preeclampsia
Severe Pregnancy Complications Are Associated With Elevated Factor VIII Plasma Activity
Congenital and acquired thrombophilia were identified as risk factors for thrombosis in systemic vessels.Thrombophilias have also been recently found to be associated with preeclampsia, intrauterine fetal growth restriction…
- Conditions
- Pregnancy Complications, Preeclampsia, Placental Abruption, Intrauterine Fetal Growth Restriction
- Trial name
- NCT00573118
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Stillbirth, Intrauterine Growth Retardation
Antenatal Detection of Fetal Growth Restriction and Stillbirths Rate.
The main objective is to assess the role of antenatal detection of fetal growth restriction (FGR) on stillbirth, by a case-control study in a population-based sample of small for gestational age (SGA) livebirths and stillbirths…
- Conditions
- Stillbirth, Intrauterine Growth Retardation, Infant, Small for Gestational Age
- Trial name
- REPERE (NCT01995968)
- Testing
- Antenatal identification of fetal growth restriction
- Where
- 21 sites in France
- Volunteers
- 480 people
- Sponsor
- University Hospital, Grenoble
Preeclampsia
Low Dose Aspirin for the Prevention of Preeclampsia
Preeclampsia is one of the three leading causes of maternal morbidity and mortality all over the world. The use of low dose aspirin has been mentioned in several studies with promising results.
- Trial name
- NCT01890005
- Testing
- Aspirin
- Where
- Panama
- Volunteers
- 476 people
- Sponsor
- Saint Thomas Hospital, Panama
Advanced Maternal Age Pregnancy, High Risk Pregnancy
University Hospital Advanced Age Pregnant Cohort
The University Hospital Advanced Age Pregnant (UNIHOPE) Cohort is the major part of the National Key Research and Development Program on Reproductive Health \& Major Birth Defects Control and Prevention Project, which is funded…
- Conditions
- Advanced Maternal Age Pregnancy, High Risk Pregnancy, Perinatal Death, Maternal Death
- Trial name
- UNIHOPE (NCT03220750)
- Where
- 9 sites in China
- Volunteers
- 22,000 people, healthy volunteers welcome
- Sponsor
- Peking University
Major Depressive Disorder, Miscarriage
Group Interpersonal Psychotherapy for Treatment of Major Depressive Disorder Following Perinatal Loss
The purpose of this study is to conduct a randomized pilot trial in a sample of 60 women who meet criteria for Major Depressive Disorder (MDD) 1-18 months after a perinatal loss to demonstrate the feasibility of the proposed…
- Conditions
- Major Depressive Disorder, Miscarriage, Stillbirth, Neonatal Death
- Trial name
- NCT01867749
- Testing
- Group Interpersonal Psychotherapy (IPT-G), Coping with Depression (CWD)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Brown University
Adverse Pregnancy Outcome
Using Placental Pathology to Prevent Recurrent Adverse Pregnancy Outcomes: A Pilot Project
The goal of this randomized clinical trial is to evaluate if we can use placental pathology in a prior pregnancy which had an adverse outcome, such as early delivery, stillbirth, a baby born smaller than expected, or severe forms…
- Trial name
- NCT06004674
- Testing
- Lovenox 40mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Endeavor Health
Stillbirth, Infant Mortality
Impact of Smoke-free Legislation on Early-life Mortality and Low Birth Weight in England
The purpose of this study is to investigate whether there has been a change in low birth weight and perinatal and infant mortality following the July 2007 introduction of a ban on smoking in public places and workplaces in…
- Conditions
- Stillbirth, Infant Mortality, Sudden Infant Death, Infant, Low Birth Weight
- Trial name
- NCT02039583
- Testing
- Smoke-free legislation
- Where
- United Kingdom
- Volunteers
- 10,291,118 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Pregnancy Outcome Trends in Low-resource Geographic Areas
Maternal Newborn Health Registry
The primary purpose of this population-based study is to quantify and understand the trends in pregnancy outcomes in defined low-resource geographic areas over time, in order to provide population-based data on stillbirths…
- Trial name
- MNH (NCT01073475)
- Testing
- There is no intervention associated with the parent MNHR study. For the MNHR COVID sub-study, participants will be asked to provide a blood specimen at or near delivery.
- Where
- 15 sites in United States, Bangladesh and 5 more
- Volunteers
- 950,000 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Premature Birth, Perinatal Mortality
Assessing the Impact of Smoke-free Legislation on Perinatal Health in the Netherlands
The purpose of this study is to investigate whether there has been a change in perinatal outcomes following the phased smoking ban introduction (January 2004 for workplaces; July 2008 for bars and restaurants) workplaces in the…
- Conditions
- Premature Birth, Perinatal Mortality, Infant, Low Birth Weight, Stillbirth
- Trial name
- NCT02189265
- Testing
- Smoke-free legislation
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 2,069,695 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Stillbirth, Fetal Death
Investigating the Structured Use of Ultrasound Scanning for Fetal Growth
Fetal growth restriction during pregnancy represents one of the biggest risk factors for stillbirth (Gardosi et al, 2013), with 'about one in three term, normally formed antepartum stillbirths are related to abnormalities of…
- Conditions
- Stillbirth, Fetal Death, Fetal Growth Retardation, Small for Gestational Age
- Trial name
- OxGRIP (NCT03662178)
- Where
- United Kingdom
- Volunteers
- 56,000 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Grief, Post Traumatic Stress Disorder
Walk With Me (WWM) for Perinatal Grief
The goal of this clinical trial is to learn if the Along With Me web-based intervention works to decrease posttraumatic stress symptoms and suicidal ideation among bereaved parents following pregnancy and early infant loss.
- Conditions
- Grief, Post Traumatic Stress Disorder, Suicidal Ideation, Miscarriage
- Trial name
- PeriGrief-II (NCT07011940)
- Testing
- Along With Me, Peer Guide
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Miscarriage, Stillbirth
Follow-up of Pregnant Women After a Mass Vaccination of Oral Cholera Vaccine (ShancholTM) in Nsanje Malawi
This study, to be carried out immediately following an emergency, reactive cholera vaccination campaign in Nsanje District, Malawi, will be a cohort study to estimate the safety of killed oral cholera vaccine (OCV), in pregnant…
- Conditions
- Miscarriage, Stillbirth, Cholera
- Trial name
- NCT02499172
- Testing
- Shanchol
- Where
- United States
- Volunteers
- 2,758 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
COVID-19, COVID-19 Pneumonia
Effect of Covid 19 Infection on Fetomaternal Outcome
The novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was discovered for the first time in December 2019 in Wuhan (China) and the disease it causes is called coronavirus disease 2019…
- Conditions
- COVID-19, COVID-19 Pneumonia, Fetal Growth Retardation
- Trial name
- NCT05160649
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Fayoum University
Maternal Death, Infant Death
Effects of a Health Workforce Capacity Building and Quality Improvement Intervention in Kinshasa
The aim of the study is to evaluate a health workforce capacity building and quality improvement intervention focused on integrated day-of-birth and post-pregnancy care at 16 hospitals in Kinshasa, Democratic Republic of Congo.
- Conditions
- Maternal Death, Infant Death, Stillbirth
- Trial name
- NCT03363308
- Testing
- training for health care workers supplmented by QI teams
- Where
- Democratic Republic of the Congo
- Volunteers
- 250 people
- Sponsor
- Jhpiego
Pregnancy, Eclampsia
A Cluster-Randomized Trial of Ultrasound Use to Improve Pregnancy Outcomes in Low Income Country Settings
In many low-income countries, the use of ultrasound by medical officers and non-physician health care staff (e.g., midwives) for antenatal identification of high risk pregnancies is a new intervention requiring authoritative…
- Conditions
- Pregnancy, Eclampsia, Placenta Previa, Stillbirth
- Trial name
- NCT01990625
- Testing
- Antenatal Ultrasound Scan
- Where
- 5 sites in Guatemala, Kenya and 3 more
- Volunteers
- 45,038 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Infant, Small for Gestational Age, Infant, Low Birth Weight
KBTH-GIRHL Healthy Birth Weight Study: A Cross-Section
This study was designed and conducted in an effort to establish a comparison group for the Ghana PrenaBelt Trial (NTC02379728). The Ghana PrenaBelt Trial examined the effect, on birth weight, of a belt-like device to help…
- Conditions
- Infant, Small for Gestational Age, Infant, Low Birth Weight, Pregnancy, Sleep
- Trial name
- KBTH-HBWS (NCT03062228)
- Where
- Ghana
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Placental Malaria Infection, HIV Infections
Intermittent Preventive Treatment of Malaria in HIV-Seropositive Pregnant Women in Zambia
Prevention of malaria in pregnancy is critical given the high incidence of malaria in Zambia and its serious impact on both maternal and infant survival.
- Conditions
- Placental Malaria Infection, HIV Infections, Stillbirth, Prematurity
- Trial name
- NCT00270530
- Testing
- Sulfadoxine-pyrimethamine (Fansidar)
- Where
- Zambia
- Volunteers
- 454 people
- Sponsor
- Center for International Health and Development
Stillbirth and Fetal Death
Intervention to Prevent Mental Health Disorders of Women and Their Partners Who Experienced Pregnancy Loss
The goal of this clinical trial is to test impact of a multiprofessional intervention in mothers and partners who suffer a pregnancy loss.
- Trial name
- Enzo (NCT06340555)
- Testing
- GUIA ATENCION MULTIDISCIPLINAR SANT BOI, USUAL CARE
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fundació Sant Joan de Déu
Obstetric Labor Complications, Stillbirth
The PartoMa Project: For Improving Monitoring, Action and Triage During Labour
OVERALL OBJECTIVE In an East African referral hospital, to develop and analyze the effect of locally agreed and achievable guidelines and a continual in-house training program for strengthening partogram-based…
- Conditions
- Obstetric Labor Complications, Stillbirth, Maternal Death
- Trial name
- PartoMa (NCT02318420)
- Testing
- The PartoMa intervention
- Where
- Tanzania
- Volunteers
- 3,087 people
- Sponsor
- Ib Christian Bygbjerg