Clinical trials: Intrauterine Insemination
Infertility
Extended Letrozole Regimen Versus Clomiphene Citrate for Superovulation in Patients With Unexplained Infertility Undergoing Intrauterine Insemination
The aim of this randomized controlled trial is to compare the efficacy of extended letrozole regimen (2.5mg/day from cycle day 1 to 9) with clomiphene citrate (100 mg/day from cycle day 3 to 7) in women with unexplained…
- Trial name
- NCT01232075
- Testing
- Extended letrozole regimen, Clomiphene citrate regimen
- Where
- 2 sites in Egypt
- Volunteers
- 214 people
- Sponsor
- Cairo University
Infertility, Spermatozoa
Ejaculatory Abstinence in IUI Cycles
Intrauterine insemination (IUI) combined with ovarian stimulation, has been an extensively used procedure for the treatment of patients with unexplained infertility.
- Conditions
- Infertility, Spermatozoa, Reproductive Disorder
- Trial name
- NCT04361292
- Testing
- INTRAUTERINE INSEMINATION
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Infertility, Female
Controlled Ovarian Stimulation and Human Uterine Lavage
This is a feasibility study intended to demonstrate the Previvo Uterine Lavage System's ability to recover embryos from the uterus following either natural cycle (NC)/intrauterine insemination (IUI), or controlled ovarian…
- Trial name
- NCT03426007
- Testing
- Uterine lavage
- Where
- Mexico
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Previvo Genetics
Infertility, Female, Anti-Mullerian Hormone Deficiency
Pregnancy Prediction Using Anti-Müllerian Hormone in Intrauterine Insemination Cycles
The goal of this study is to compare the cumulative pregnancy rates after 4 artificial inseminations with donor (IAD) in non-sterile women with plasma AMH levels > and < 1.1 ng/mL.
- Trial name
- NCT06263192
- Testing
- Intrauterine insemination
- Where
- Spain
- Volunteers
- 342 people
- Sponsor
- Jose Antonio Moreno
No Explained Sterility
Step Up Versus Step Down in Controlled Ovarian Stimulation
The aim of the study is to evaluate if the Step up protocol is equal or superior regarding efficacy and security than the step down protocol. In couple submitted two intrauterine insemination.
- Trial name
- NCT01376999
- Testing
- FSH-r (Follicule stimulate hormone)
- Where
- Spain
- Volunteers
- 158 people
- Sponsor
- Parc de Salut Mar
Infertility, Male Infertility
The Efficiency of a New Sperm-Wash Device for Intrauterine Insemination in Couples With Infertility
This study evaluates the effectiveness of a novel sperm-wash device designed to improve outcomes in intrauterine insemination (IUI) for couples with infertility.
- Trial name
- IUI (NCT06956287)
- Testing
- LensHooke CA0, Density Gradient Centrifugation (DGC)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chung Shan Medical University
Unexplained Infertility
Cost-effective Treatment of Unexplained Infertility
The issue of unexplained infertility that Southam brought up in 1960 is still a problem today. Despite improvements in infertility assessment, many couples still don't know why they are infertile.
- Trial name
- NCT06178523
- Testing
- Clomiphene Citrate., Sildenafil Citrate, Intrauterine Insemination
- Where
- Saudi Arabia
- Volunteers
- 900 people
- Sponsor
- Batterjee Medical College
Unexplained Infertility, Polycystic Ovarian Syndrome
Nimodipine to Prevent LH Surge During Ovulation Induction: Blinded Placebo-controlled RCT
The main purpose of this study is to test the effectiveness of nimodipine in preventing a luteinizing hormone (LH) surge in women undergoing ovulation induction with clomiphene citrate.
- Conditions
- Unexplained Infertility, Polycystic Ovarian Syndrome, Anovulatory
- Trial name
- NIMO (NCT01672801)
- Testing
- Nimodipine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boston IVF
The Study Focusses on Improving the Implantation Rate in IVF
Effect of Intrauterine Navigation Using Intrauterine Insemination Catheter for Mock Embryo Transfer Prior to Day 3 Embryo Transfer on Pregnancy Rate: A Pilot Study
Objective: To evaluate the effect of intrauterine navigation using intrauterine insemination catheter (IUI) one day prior to day 3 embryo transfer (ET) on pregnancy rate. Design: Pilot randomized controlled study.
- Trial name
- NCT03358732
- Testing
- endometrial navigation one day before the embyo transfer using IUI catheter ,
- Where
- Saudi Arabia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
Infertility, Pertubation
Effect of Pertubation on Pregnancy Rates Before Intrauterine Insemination Treatment
To demonstrate a possible beneficial impact of pertubation we designed a randomized prospective study, in which uterine washing was administered prior to insemination in patients diagnosed with unexplained infertility.
- Conditions
- Infertility, Pertubation, Insemination
- Trial name
- NCT01999959
- Testing
- Pertubation
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Gazi University
Progesterone
Comparison of the Effect of Subcutaneous Progesterone and Vaginal Progesterone for Luteal Phase Support
The invesigators aimed to seperate the patients,which is going to be applied IUI, to two different groups as prospective randomized controlled ;assess the efficacy of the two different way pressurised progesterone by appling…
- Trial name
- NCT05276531
- Testing
- subcutaneous progesterone, vaginal progesterone
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Infertility
SU Versus GD for Sperm Preparation in IUI
Intrauterine insemination (IUI) is the first-line treatment for couples with unexplained and mild male factor infertility. The result of IUI depends on many factors including the sperm preparation techniques.
- Trial name
- NCT04477356
- Testing
- SU, DG
- Where
- Vietnam
- Volunteers
- 912 people
- Sponsor
- Mỹ Đức Hospital
Subfertility
Stimulated Versus Un-stimulated Intrauterine Insemination Cycles in Women With Endometriosis
Four hundred and fifty women with endometriosis will be divided into 3 equal groups using computer generated random numbers: Group 1 will have up to 4 stimulated intrauterine insemination (IUI) cycles, group 2 will have up to 4…
- Trial name
- NCT02470169
- Testing
- Merional, IUI, Choriomon
- Where
- 2 sites in Egypt
- Volunteers
- 450 people
- Sponsor
- Cairo University
Sterility
Comparative Assessment of the Clinical Utility of Ovarian Stimulation With Menotropin Versus Menotropin Plus GnRH Antagonist
To assess the effectiveness of protocols of ovarian hyperstimulation combining urinary gonadotrophins + GnRH antagonist vs urinary gonadotrophins, to achieve clinical pregnancy in females undergoing intrauterine insemination.
- Trial name
- PROMENIA (NCT01331733)
- Testing
- hMG-HP, hMG + GnRH antagonist
- Where
- 7 sites in Spain
- Volunteers
- 131 people
- Sponsor
- Ferring Pharmaceuticals
Infertility
Effect of Cervical Occlusion During Intrauterine Insemination (IUI)
Study Hypothesis: There is a difference in pregnancy rates between intrauterine insemination (IUI) in cycles performed with cervical occlusion by a balloon catheter designed for sonohysterograms as compared to those performed…
- Trial name
- NCT00951171
- Testing
- Intrauterine Insemination, IUI with the standard inseminator
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Pregnancy, Live Birth
Folic Acid and Zinc Supplementation Trial (FAZST)
The overarching goal of this trial is to determine if an intervention comprising folic acid and zinc dietary supplementation improves semen quality and indirectly fertility outcomes (i.e., live birth rate) among couples trying to…
- Conditions
- Pregnancy, Live Birth, Spontaneous Abortion
- Trial name
- FAZST (NCT01857310)
- Testing
- 5 mg folic acid and 30 mg elemental zinc
- Where
- 4 sites in United States
- Volunteers
- 2,370 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infertility
Intrauterine Insemination and Nursing
This study investigates the effect of virtual reality glasses use and therapeutic touch on pain, anxiety and patient satisfaction in women during intrauterine insemination procedure
- Trial name
- NCT05192330
- Testing
- Virtual Reality Glasses, Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Infertility
Intrauterine Insemination Predictor Factors
Multiple studies have reported on the impact of factors such as female age, duration of infertility, type of infertility, hormone levels (i.e.
- Trial name
- NCT03836118
- Testing
- Homologous intrauterine insemination (IUI)
- Where
- Italy
- Volunteers
- 2,970 people
- Sponsor
- Istituto Clinico Humanitas
Oxidative Stress
The Effect of the Sexual Abstinence Period on the Production of Reactive Oxygen Species in Patients Who Planned to Take Part in Intrauterine Insemination
To determine the ideal sexual abstinence time for producing high quality sperm
- Trial name
- NCT02401997
- Testing
- sexual abstinence
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gazi University
Infertility, Infertility Secondary
Sperm Preparation Prior to Intrauterine Insemination Study
This is a randomized controlled trial comparing density gradient centrifugation and microfluidic sperm sorting in patients undergoing intrauterine insemination to evaluate cumulative pregnancy outcomes.
- Conditions
- Infertility, Infertility Secondary, Infertility Unexplained, Anovulation
- Trial name
- PIoUS (NCT05693220)
- Testing
- Zymot Multi sperm separation device, Density gradient centrifugation
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of California, San Francisco