Clinical trials: Intrauterine Insemination
Infertility
Does Endometrial Injury Improve Intrauterine Insemination Outcome?
The investigator suggests that local endometrial injury using pipelle catheter performed in the follicular phase (cycle day 5, 6 or 7) of the stimulation cycle may improve the pregnancy rates among patients undergoing…
- Trial name
- NCT02542280
- Testing
- endometrial injury., intrauterine insemination, ovarian stimulation
- Volunteers
- 360 people
- Sponsor
- Ain Shams Maternity Hospital
Infertility
Automated Sperm Sample Preparation Protocol
This clinical trial would be directed at determining the effectiveness of an innovative sperm sample preparation protocol for intrauterine insemination (IUI).
- Trial name
- NCT03999762
- Testing
- sample prep
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Nanonc Inc.
Infertility, HIV Infections
HIV-discordant Couple Intrauterine Insemination
The investigators propose to treat couples who wish to have a child in which the man is HIV-positive and the woman is HIV-negative. The investigators call these couples HIV-discordant.
- Trial name
- NCT00975546
- Testing
- Sperm washing and testing for HIV contamination, Intrauterine Insemination
- Where
- United States
- Sponsor
- University of Missouri-Columbia
Infertility, Insemination
Pozzi Forceps in Intrauterine Insemination
Many infertility and subfertility issues are treated nowadays with intrauterine inseminations. This is a minimally invasive technique that consists in placing sperm into a woman's uterus.
- Trial name
- NCT03435809
- Testing
- Intrauterine insemination
- Where
- Canada
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Infertility
36 Versus 42 Hour Time Interval From Ovulation to Intrauterine Insemination
The purpose of this study is to prove that a higher clinical pregnancy rate can be achieved with a 42 to 44 hour time interval between ovulation trigger and intrauterine insemination than a 36 to 38 hour time interval in…
- Trial name
- NCT02210611
- Testing
- Intrauterine Insemination 36 hours, Intrauterine Insemination 42 hours
- Where
- Israel
- Volunteers
- 71 people
- Sponsor
- HaEmek Medical Center, Israel
Compare Pregnancy Rates Between FSH Stimulation and FSH and, GnRH Antagonist
Single Injection of Ganirelix in Gonadotropin Intrauterine Insemination (IUI) Cycles
Ovulation induction (OI) using gonadotropins is one of the most widely prescribed treatments of infertility. One common problem encountered while attempting OI using gonadotropins is premature ovulation.
- Trial name
- NCT01286051
- Testing
- Follistim administration, Follistim plus Ganirelix
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Houston Fertility Institute
Infertility
Pre-washing the Catheter With a Culture Medium Before Intrauterine Insemination
The aim of the study to evaluate the possible effect of washing the insemination catheters before intrauterine insemination on the pregnancy outcomes.
- Trial name
- NCT04736459
- Testing
- Pre-washed catheter vs. Unwashed catheter in the intrauterine insemination
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Infertility
Study Evaluating the Timing of Intrauterine Insemination in Relation to Positive Home Ovulation Prediction Kit
The aim of this study is to assess the impact of the timing of intrauterine insemination (IUI) in relation to the natural surge of luteinizing hormone (LH), as detected by home ovulation predictor kits, on pregnancy rates per…
- Trial name
- NCT02294773
- Testing
- Intrauterine Insemination, Clomiphene, Letrozole
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Midwest Fertility Specialists
Reproductive Issues
The Efficacy and Safety of Female PRP Co-incubation With Sperm During (IUI) Cycles
The investigators hypothesize that infertility patients undergoing IUI who receive female autologous platelet-rich plasma (PRP) co-incubation with husband's sperm would have higher clinical pregnancy rate.
- Trial name
- NCT07615634
- Testing
- non-PRP group (control group), PRP group (intervention group)
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Chinese University of Hong Kong
Infertility Unexplained, Infertility, Male
Comparison of the Effect of Microchip and Density Gradient Methods in Intrauterine Insemination Cycles
Microfluidic chips are one of the methods of sperm separation to eliminate DNA fragmentation in sperm. It is thought that the separation of sperm by centrifugation in the classical gradient density (Percoll) method used in sperm…
- Trial name
- NCT04144244
- Testing
- MicroFluidic Sperm Sorting Chips, Gradient-Density Centrifugation
- Where
- Turkey (Türkiye)
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Relationship of Progesterone Levels and Pregnancy
The Effect of Progesterone Levels on Pregnancy
The aim of this study is to investigate the effect of progesterone levels on pregnancy occurrence on the 3rd and 5th days after insemination.
- Trial name
- NCT04707430
- Testing
- blood progesterone test
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Sezcan Mumusoglu
Infertility
Luteal Phase Progesterone in IUI and Gonadotropin Cycles
This is a study of patients undergoing Controlled Ovarian Hyperstimulation (COH) with Gonadotropins and Intrauterine Insemination (IUI) at a Fertility Clinic.
- Trial name
- NCT01941875
- Testing
- Progesterone Effervescent Vaginal Tablets
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Infertility
Combining LHu With Ultrasound Monitoring in IUI
Intra-uterine insemination (IUI), generally in combination with ovarian stimulation, is one of the most commonly used treatments for infertility.
- Trial name
- NCT01205555
- Testing
- urine LH testing
- Where
- Canada
- Volunteers
- 367 people
- Sponsor
- Clinique Ovo
Infertility
Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success
In this study the investigators took the opportunity of having a large sample of IUI cycles in a single centre to try to analyse the effect of stimulation protocols and of the infertility origin on the results, taking in account…
- Trial name
- GONADOTROP (NCT03669276)
- Where
- France
- Volunteers
- 1,251 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Infertility
Sperm Motility and IUI Live Birth Rate
This prospective cohort study aims to establish a cut-off threshold for pre-washed total rapidly motile sperm count (TRMSC) based on WHO 2021 criteria to predict the live birth rate following intrauterine insemination (IUI).
- Trial name
- IUI (NCT06117995)
- Testing
- Assessment the pre-washed sperm motility before IUI
- Volunteers
- 536 people
- Sponsor
- Mỹ Đức Hospital
Endometriosis I-II
Role of Intrauterine Insemination in Patients With Endometriosis I-II
Intrauterine insemination (IUI) is an ART that provides good results in selected patients, improving their reproductive prognosis. Endometriosis I y II, according to ASRM classification, remains an indication to perform IUI.
- Trial name
- NCT03425604
- Testing
- Intrauterine insemination
- Volunteers
- 9,979 people
- Sponsor
- IVI Bilbao
Infertility, Intrauterine Insemination
Personalized Insemination Treatment Study
This study is intended for women undergoing their first cycle of 3 intrauterine inseminations. All 3 inseminations will be personalized by using algorithms to determine the dose of study medication.
- Conditions
- Infertility, Intrauterine Insemination, Reproduction
- Trial name
- PITS (NCT03830723)
- Testing
- Follitropin delta
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Clinique Ovo
Infertility
A Phase II Clinical Study of Lidocain Pertubation as Treatment for Couples With Unexplained Infertility
The study tested the hypothesis that a pertubation with a lidocain solution will enhance pregnancy rate.
- Trial name
- NCT00449449
- Testing
- Pertubation with Lidocain Solution
- Where
- Sweden
- Volunteers
- 330 people
- Sponsor
- Isifer AB
Infertility
Luteal Support and Intrauterine Insemination (IUI) With Clomiphene Citrate
The purpose of this study is to assess the effect of luteal phase supplement (LPS) on pregnancy rate in IUI cycles stimulated with clomiphene citrate.
- Trial name
- NCT01046708
- Testing
- micronized progesterone
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Pregnancy
Timing of Intrauterine Insemination (IUI) 24 or 48 Hours After Spontaneous Luteinizing Hormone (LH) Peak
The aim of the present study is to prospectively evaluate whether performing an intra-uterine insemination 24 hours after the spontaneous LH peak may result in significantly higher ongoing pregnancy rates compared to 48 hours.
- Trial name
- NCT01622023
- Testing
- intra-uterine insemination
- Where
- Belgium
- Volunteers
- 435 people
- Sponsor
- Universitair Ziekenhuis Brussel