Clinical trials: Intravascular Volume
Hemorrhage
Comparison of Compensatory Reserve Index to Changes in Stroke Volume and Intravascular Volume
The purpose of this study is to demonstrate the correlation of the Compensatory Reserve Index (CRI) numeric and graphical trend readings to intravascular volume changes as compared to graded blood loss (removal of 20% of…
- Trial name
- NCT02980471
- Testing
- Pulse Oximeter
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Flashback Technologies
Lumbar Spine Surgery, Hemodynamic Changes
IVC Collapsibility Index in Lumbar Stabilization Surgery
This study aims to evaluate perioperative hemodynamic changes using the inferior vena cava (IVC) collapsibility index in patients undergoing lumbar stabilization surgery under general anesthesia.
- Conditions
- Lumbar Spine Surgery, Hemodynamic Changes, Intravascular Volume Status
- Trial name
- NCT07549165
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Septic Shock, Vein Collapsibility
Fluid Responsiveness in Septic Shock Evaluated by Caval Ultrasound Doppler Examination
The study aims at clarification of venous collapsibility measures with real venous flow measurements during dynamic maneuver testing fluid responsiveness in septic shock patients.
- Conditions
- Septic Shock, Vein Collapsibility, Intravascular Doppler, Volume Responsiveness in Septic Shock
- Trial name
- FRIEND (NCT02676427)
- Testing
- passive leg raising
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Charles University, Czech Republic
Intensive Care
Measurement of Cardiac Output and Intravascular Volume Status in Children Using COstatus (SH)
Assessment and monitoring of cardiac function in the pediatric intensive care unit (PICU) is an integral part of hemodynamic monitoring of critically ill patients whether it is done directly or indirectly.
- Trial name
- NCT01613859
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Transonic Systems Inc.
Antithrombin III Levels, Albumin Levels
Albumin Utilization in Adult Cardiac Surgical Patients : A Multicentre Prospective Cohort Study
The goal of our proposed multicentre prospective cohort study is to characterize perioperative usage patterns of crystalloids and albumin, as well as key patient outcomes, in cardiac surgical patients.
- Trial name
- AlbACS-1Pro (NCT06395480)
- Where
- 2 sites in Canada
- Volunteers
- 104 people
- Sponsor
- University Health Network, Toronto
Hypotension, Sepsis
Carotid Doppler Ultrasound for the Measurement of Intravascular Volume Status
Ultrasound represents an attractive non-invasive method to assess hemodynamic status. Understanding dynamic changes in hemodynamics in situations such as hypovolemia, sepsis, and cardiogenic shock can potentially help improve…
- Trial name
- NCT02907931
- Testing
- Point of Care Ultrasound
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yale University
Intravascular Volume
Internal Jugular Vein Distensibility and Pleth Variability Index(PVI) for Evaluating Fluid Responsiveness
Assessment of intravascular volume status is crucial in order to predict the efficacy of volume status in major abdominal surgery.
- Trial name
- NCT03673475
- Testing
- Assessment of fluid responsiveness
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Tepecik Training and Research Hospital
Coronary Artery Disease
Effects of Combined Therapy With Statin Plus Fenofibrate on Coronary Atherosclerotic Plaque Compared With Statin Alone
The purpose of this study is to determine effects of combination therapy with rosuvastatin and fenofibrate on atheromatous plaques and its tissue characteristics of de novo coronary lesions with intermediate stenosis in patient…
- Trial name
- NCT02232360
- Testing
- Rosuvastatin and fenofibrate, Rosuvastatin alone
- Where
- 6 sites in South Korea
- Volunteers
- 106 people
- Sponsor
- Gachon University Gil Medical Center
Congestive Heart Failure
Blood Volume and Hemodynamic Analysis in Patients With Chronic Heart Failure
The primary hypothesis is that patients with HFREF (heart failure with reduced ejection fraction) will demonstrate a markedly expanded intravascular volume which will correlate with elevated right heart hemodynamics and increased…
- Trial name
- NCT02120014
- Testing
- blood volume measurement, venous plethysmography
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Positive-Pressure Respirations, Respiratory Failure
Inferior Vena Cava Indexes in Positive Pressure Supports
Collapsibility (CI-IVC), distensibility (dIVC) and delta (ΔIVC) indices, which are dynamic measures of inferior vena cava (IVC) diameter, are used to assess the intravascular volume status in critically ill patients.
- Trial name
- NCT03452046
- Testing
- IVC diametres
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Tepecik Training and Research Hospital
Heart Failure
Intravascular Volume Expansion to Neuroendocrine-Renal Function Profiles in Chronic Heart Failure
Researchers are trying learn more about how the heart and blood volume interact in subjects with heart failure and how measuring blood volume may help them develop better ways of treating and managing heart failure patients.
- Trial name
- NCT04156854
- Testing
- Quantitated Blood Volume Analysis
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Blood Loss, Surgical, Fluid Retention
Comparison Between Hyperoncotic and Isooncotic Albumin to Support Blood Loss Replacement
Fluid intravascular replacement is usually performed with either balanced crystalloids or iso-oncotic colloids, (synthetic colloids, plasma and 5% albumin).
- Trial name
- VASCALB (NCT05391607)
- Testing
- Hyperoncotic Albumin 20%, Isooncotic Albumin 5%, Ringer's Lactate Crystalloid Solutions (control group)
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Intravascular Volume
Noninvasive Assessment of Intravascular Volume Status for Postoperative Patients
Ultrasound measurements of the inferior vena cava (IVC) have been proposed as a noninvasive tool to help guide fluid management.
- Trial name
- NCT03766451
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Beni-Suef University
Intraoperative Complications
Hydroxyethyl Starch (130/0.4) for Intravascular Volume Therapy in Liver Transplantation
There are no standardized plasma volume replacement protocols during liver transplantation surgery. The current study is designed to compare efficacy, safety, and costs of perioperative volume replacement with Voluven…
- Trial name
- NCT00308100
- Testing
- Hydroxyethylstarch 130/0.4, 5% Albumin
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Fresenius Kabi
Hypercholesterolemia, Acute Coronary Syndrome
Evaluation of Effect of Alirocumab on Coronary Atheroma Volume in Japanese Patients Hospitalized for Acute Coronary Syndrome With Hypercholesterolemia
Primary Objective: To compare the efficacy of alirocumab (Praluent®) with standard of care (SoC) on coronary atheroma progression (percent change in normalized total atheroma volume [TAV]) after 9 months of treatment in…
- Trial name
- ODYSSEY J-IVUS (NCT02984982)
- Testing
- Alirocumab SAR236553, Atorvastatin, Rosuvastatin
- Where
- 39 sites in Japan
- Volunteers
- 206 people
- Sponsor
- Sanofi