Clinical trials: Intravenous
Intravenous Anesthetic Agent Overdose
Propofol Pharmacokinetics and Pharmacodynamics Modelling
The main purpose of this research is to develop a population pharmacokinetic and pharmacodynamic model of Propofol when used for induction and maintenance of anaesthesia, using BIS as a pharmacodynamic endpoint.
- Trial name
- NCT02713698
- Testing
- Propofol
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- Centro Hospitalar do Porto
Intravenous Catheterization
Virtual Reality vs Standard-of-Care for Comfort During Intravenous Catheterization
Children often need an intravenous catheter placement for delivery of fluids and medications, a procedure associated with pain and anxiety. In the Emergency Department topical anesthetics are frequently used.
- Trial name
- NCT03681730
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of British Columbia
Intravenous Injections
A Randomized Controlled Open Label Trial to Assess the Safety and Efficacy of the OptiVein IV Catheter in an Oncologic Population
A prospective, single-center, open-label, randomized controlled trial to assess the safety and efficacy of the OptiVein IV Catheter in an oncology population.
- Trial name
- NCT02420028
- Testing
- Insertion of OptiVein IV catheter, Insertion of Vasofix Certo IV catheter
- Where
- Finland
- Volunteers
- 109 people
- Sponsor
- Optomeditech Oy
Injections, Intravenous, Administration, Intravenous
A Trial to Demonstrate the Safety and Efficacy of the OptiVein IV Catheter In a Pediatric Population
A prospective, single-center, open-label, randomized controlled trial to demonstrate the safety and efficacy of the OptiVein IV Catheter in the pediatric population.
- Trial name
- NCT03145519
- Testing
- Vasofix Certo Catheter, OptiVein Catheter
- Where
- Estonia
- Volunteers
- 188 people
- Sponsor
- Optomeditech Oy
Injections, Intravenous
Comparison of Two Techniques of IV Lidocaine on Propofol Injection Pain
Intravenous lidocaine is commonly given through an intravenous (IV) line prior to injection of propofol to reduce the amount of pain during propofol injection.
- Trial name
- NCT03057704
- Testing
- Lidocaine injection flushed, Lidocaine injection tourniquet
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Difficult Intravenous Access in Pediatrics
Ultrasound Guided IV Access in a Pediatric Emergency Department
The primary objective is to determine whether the use of ultrasound guidance compared to standard IV access improves the proportion of successful IV placement on a first attempt for children in a pediatric emergency department…
- Trial name
- USgIV (NCT02125552)
- Testing
- Ultrasound guidance, Traditional intravenous access
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Children's Hospital of Philadelphia
Hepatitis C, Drug Abuse, Intravenous
The TAP Study: Treating People Who Inject Drugs in Community-Based Settings Using a Social Network Approach
This study will investigate the feasibility of treating people who inject drugs (PWID) with hepatitis C virus (HCV) in community-based settings with a 12-week course of oral therapy combination of sofosbuvir plus ledipasvir.
- Trial name
- TAP (NCT02363517)
- Testing
- Sofosbuvir/ledispasvir fixed dose combination (SOF + LDP)
- Where
- Australia
- Volunteers
- 420 people
- Sponsor
- Macfarlane Burnet Institute for Medical Research and Public Health Ltd
Anesthesia, Intravenous
Target Effect-site Concentration of Remifentanil in Transperineal Prostate Puncture
The research about the target effect-site concentration of remifentanil, inhibiting stress reaction of the perineal prostate puncture when Dexmedetomidine being continuous pumping
- Trial name
- NCT03428191
- Testing
- Remifentanyl+Dexmedetomidine
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chinese Medical Association
Cocaine-Related Disorders, Opioid-Related Disorders
The Therapeutic Workplace Initiation Study
The primary purpose of the study is to determine if the central feature of the Therapeutic Workplace, the abstinence reinforcement contingency, is critical to initiate cocaine abstinence in injection drug using methadone patients…
- Conditions
- Cocaine-Related Disorders, Opioid-Related Disorders, Heroin Dependence, Substance Abuse, Intravenous
- Trial name
- NCT00249470
- Testing
- Abstinence & Work, Work Only
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Johns Hopkins University
Anaesthesia, General, Anesthesia, Intravenous
Oxygenation by 100% Oxygen Via High Flow Nasal Cannula in Surgical Patients
Oxygenation with high-flow nasal cannula with 100% oxygen has only been evaluated in a limited number of studies. Although data are convincing it is of importance to evaluate this new concept in our department before implementing…
- Conditions
- Anaesthesia, General, Anesthesia, Intravenous, Ventilation
- Trial name
- NCT02706431
- Testing
- Hyperventilation
- Volunteers
- 31 people
- Sponsor
- Karolinska University Hospital
Cocaine-Related Disorders, Heroin Dependence
Employment-based Reinforcement of Naltrexone Ingestion and Abstinence
A randomized study is planned over 5 years to evaluate the effectiveness of the Therapeutic Workplace in promoting naltrexone ingestion and abstinence in unemployed opiate-dependent injection drug users.
- Conditions
- Cocaine-Related Disorders, Heroin Dependence, Opioid-Related Disorders, Substance Abuse, Intravenous
- Trial name
- NCT00149669
- Testing
- employment-based reinforcement
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Johns Hopkins University
Intravenous Anesthetic Agent Overdose
Interest of a Tetanus Test at a Fixed Remifentanil Concentration Before Laryngoscopy and Skin Incision
Individually-tailored administration of the opioid analgesic component during general anaesthesia is still a challenge for the anesthesiologist.
- Trial name
- NCT02884310
- Testing
- Remifentanil adapted to SPI, Remifentanil fixed
- Volunteers
- 48 people
- Sponsor
- Erasme University Hospital
Preemptive Intravenous Ibuprofen, Intraoperative Analgesia
Impact of Preemptive Intravenous Ibuprofen on Intraoperative Analgesia in Third Molar Teeth
This study was planned to evaluate the analgesic efficacy of preemptive intravenous (iv) ibuprofen on pain occurring during and after the mandibular third molar surgeon
- Trial name
- NCT03170726
- Testing
- arveles, intrafen 800 mg, plasebos
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erzincan University
Elective Surgery, Intravenous Anesthesia
Preoperative Anxiety's Incidence and Related Factors in Surgical Patients
Preoperative anxiety is often described as an uncomfortable, tense unpleasant mood before surgery, an emotional response to a potential challenge or threat to reality.
- Conditions
- Elective Surgery, Intravenous Anesthesia, Preoperative Anxiety
- Trial name
- NCT03162692
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Xuzhou Medical University
Balanced Anesthesia, Intracerebral Hemorrhage
Hemodynamics and Vital Organ Function in Intracerebral Hemorrhage
Spontaneous non-traumatic intracerebral hemorrhage (ICH) is a common symptom in clinical practice and is the most serious among all types of stroke.Recently, as a relatively mainstream and recognized INTERACT2 (five well-known…
- Conditions
- Balanced Anesthesia, Intracerebral Hemorrhage, Total Intravenous Anesthesia
- Trial name
- NCT03129009
- Testing
- Total intravenous anesthesia group, Balanced anesthesia group
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xuzhou Medical University
Immunoglobulins, Intravenous, Hemolysis
Isoagglutinins in the Development of IVIG-associated Hemolysis
Patients at high risk of IVIG-associated hemolysis (defined as receipt of a 28-day cumulative dose of ≥ 2 g/kg, adjusted for ideal body weight, and non-O blood group) will be prospectively monitored using a standardized protocol…
- Trial name
- NCT02259478
- Where
- 6 sites in Canada
- Volunteers
- 144 people
- Sponsor
- Toronto Transfusion Medicine Collaborative
Indication for Peripheral Intravenous Catheterization
Study to Assess Electrocardiogram Waveforms Produced Through the Utilization of the Sherlock 3CG™ Tip Confirmation System
This study was to gather real-time ECG data through the use of the SHERLOCK 3CG™ Tip Confirmation System (TCS), an electrocardiogram (ECG)-based peripherally-inserted central catheter (PICC) tip confirmation technology.
- Trial name
- MODUS (NCT03028090)
- Testing
- SHERLOCK 3CG™ Tip Confirmation System with MODUS Software
- Where
- 2 sites in United States
- Volunteers
- 182 people
- Sponsor
- C. R. Bard
Cocaine-Related Disorders, Drug Administration Schedule
Drug Interaction Study With NS2359 and Cocaine in Cocaine Experienced Volunteers - 1
The purpose of this study is to conduct a drug interaction study with NS2359 and cocaine in cocaine experienced volunteers.
- Conditions
- Cocaine-Related Disorders, Drug Administration Schedule, Infusions, Intravenous
- Trial name
- NCT00032916
- Testing
- NS2359
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cocaine-Related Disorders, Drug Administration Schedule
Evaluation of Modafinil as a Cocaine Treatment Medication and Interactions With Cocaine - 1
The purpose of this study is to evaluate modafinil, a cocaine treatment medication, and its interactions with intravenous (IV) cocaine.
- Conditions
- Cocaine-Related Disorders, Drug Administration Schedule, Infusions, Intravenous
- Trial name
- NCT00033046
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cocaine-Related Disorders, Infusions, Intravenous
Cocaine-Metyrapone Interaction Study - 1
The purpose of this study is to examine the safety of two consecutive days of metyrapone (MRP) in subjects who may use cocaine concurrently.
- Trial name
- NCT00033098
- Testing
- Metyrapone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute on Drug Abuse (NIDA)