Clinical trials: Intravenous
Nonconvulsive Seizures
Intravenous Lacosamide Compared With Fosphenytoin in the Treatment of Patients With Frequent Nonconvulsive Seizures
This a phase 2 study comparing the efficacy of intravenous (IV) lacosamide (LCM) with IV fosphenytoin (fPHT) in controlling frequent nonconvulsive seizures (NCSs), the Adverse Events profile of LCM compared with fPHT when used to…
- Trial name
- TRENdS (NCT01458522)
- Testing
- fPHT, LCM
- Where
- 11 sites in United States
- Volunteers
- 74 people
- Sponsor
- Aatif Husain
Cystic Fibrosis
Virtual Care in CF (VIRTUAL-CF) Study
Cystic fibrosis (CF) is the most common fatal inherited condition in Caucasians, causing recurrent chest infections (pulmonary exacerbations).
- Trial name
- NCT03069651
- Testing
- Virtual Care
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Heart of England NHS Trust
Healthy Volunteer
A Bioavailability and Pharmacokinetic Study of Subcutaneous and Intravenous RO6811135 in Healthy Volunteers
This open-label, randomized, 2-way crossover study will assess the absolute bioavailability and pharmacokinetics of RO6811135 in healthy male volunteers.
- Trial name
- NCT01802853
- Testing
- RO6811135
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Amphetamine-Related Disorders
Assessment of Potential Interactions Between Methamphetamine and Selegiline - 1
The purpose of this study is to assess the potential interactions between intravenous methamphetamine and oral selegiline.
- Trial name
- NCT00033072
- Testing
- Selegiline
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Anemia of Chronic Kidney Disease
Comparison Study of Two Iron Compounds for Treatment of Anemia in Hemodialysis Patients
Patients with end-stage kidney disease on maintenance hemodialysis frequently require iron supplementation to compensate for ongoing iron losses, and to maintain hemoglobin levels with or without additional use of…
- Trial name
- COPEFER (NCT02198495)
- Testing
- Supplementation of ferric carboxymaltose, Supplementation of iron sucrose
- Where
- 2 sites in Austria
- Volunteers
- 143 people
- Sponsor
- Medical University of Vienna
Cholestasis, Jaundice, Obstructive
SMOFlipid to Lessen the Severity of Neonatal Cholestasis
Parenteral nutrition (PN) provides intravenous nutritional supplementation for infants unable to absorb adequate enteral nutrients secondary to insufficient intestinal length or function.
- Trial name
- NCT02721277
- Testing
- SMOFlipid
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Florida
Colicystitis
Comparison of the Effectiveness of Intraoperative Intravenous Lidocaine and Intravenous Remifentanil in Postoperative Pain Management in Laparoscopic Cholecystectomy
This study aims to compare the effects of intraoperative intravenous lidocaine and intravenous remifentanil on postoperative pain management in patients undergoing laparoscopic cholecystectomy under general anesthesia.
- Trial name
- NCT07312877
- Testing
- Lidocaine, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Obesity, Malnourished
Using Exhaled Air to Determine Changes in Nutritional Status of Patients on Intravenous Nutrition
Carbon-12 and carbon-13 are naturally-occurring isotopes that are found in exhaled breath. Investigators have proved that the 13CO2/12CO2 breath delta value (BDV) changes in subjects who were in negative energy balance then fed a…
- Conditions
- Obesity, Malnourished, Fasting
- Trial name
- UEAIVN (NCT02843256)
- Testing
- Isomark Canary
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Hip Fracture, Surgical Intervention
Efficacy and Safety of Intravenous Iron Sucrose in Patients With Hip Fracture to Prevent Perioperative Anemia
The purpose of this study is to evaluate the safety and efficacy of intravenous iron sucrose in patients with hip fracture and surgical intervention to prevent perioperative anemia.
- Trial name
- NCT01084122
- Testing
- Iron sucrose
- Where
- Spain
- Volunteers
- 360 people
- Sponsor
- Hospital Clinic of Barcelona
Antimycotic for Systematic Use
Evaluate Bioequivalence of Voriconazole(200mg/Vial) .
A Randomized, Single-dose, Two-way Crossover Study to Evaluate Bioequivalence of Two Formulations of Voriconazole(200mg/Vial) After Intravenous Infusion of 200mg Voriconazole in Healthy Volunteers Under Fasting Conditions.
- Trial name
- NCT04552353
- Testing
- Vaway
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Yung Shin Pharm. Ind. Co., Ltd.
Intravenous Drug Usage
Median Effective Dose of Dexmedetomidine in Elective Upper Limb Lidocaine Intravenous Regional Anesthesia
Auxiliary drugs augment the effect of local anesthetic in intravenous regional anesthesia (IVRA). The purpose of our study was to estimate the median effective dose (ED50) of Dexmedetomidine in elective upper limb Lidocaine 0.5%…
- Trial name
- dexdix (NCT04304157)
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- South Valley University
Postoperative Sore Throat, Cough, Hoarseness
Effect of Intravenous Lidocaine and Dexamethasone Combination on Postoperative Sore Throat, Cough and Hoarseness.
Post operative sore throat (POST) following tracheal intubation is a common problem causing dissatisfaction and discomfort to the patients.
- Trial name
- NCT01990781
- Testing
- LD: Lidocaine and dexamethasone, L:Lidocaine, D: Dexamethasone
- Where
- Nepal
- Volunteers
- 180 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Healthy Volunteers
Multiple Dose Escalation Study of M201-A in Healthy Japanese Subjects
This Phase I is designed to evaluate the safety, tolerability and pharmacokinetics of multiple ascending doses of M201-A administered by multiple continuous intravenous injection in Healthy Japanese subjects.
- Trial name
- NCT04464681
- Testing
- M201-A Injection
- Where
- Japan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Kitasato University
Healthy
Safety, Tolerability and Pharmacokinetics of Single Rising Intravenous Doses of BI 44370 BS Solution in Healthy Male Volunteers
Study to investigate safety, tolerability, and pharmacokinetics of BI 44370 BS solution for intravenous (i.v.) infusion
- Trial name
- NCT02215031
- Testing
- BI 44370
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Coxarthrosis, Avascular Necrosis of Hip
Effect of Peri-operative Glucocorticoids on Short-term Functional Outcome After THA
This randomized, single surgeon, placebo controlled, double blind study will be conducted in order to investigate whether or not peri-operative high doses of intravenous glucocorticoids improve short-term functional outcome after…
- Trial name
- DEXA (NCT04317872)
- Testing
- High dose of peri-operative intravenous dexamethasone, Low dose of peri-operative intravenous dexamethasone
- Where
- Belgium
- Volunteers
- 71 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Anesthesia, General
Automated Anesthesia During Bronchoscopy
The purpose of this study is to compare manual administration of propofol and remifentanil and dual closed-loop using bispectral index as the control variable during rigid bronchoscopy.
- Trial name
- NCT00571181
- Testing
- Closed-loop system, TCI (Infusion Toolbox)
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Hopital Foch
Polyneuropathies
The Impact of IVIG Treatment on Critical Illness Polyneuropathy and/or Myopathy in Patients With MOF and SIRS/Sepsis
Critical illness polyneuropathy and/or myopathy (CIPNM) is a severe complication of critical illness. Retrospective data suggest that early application of IgM-enriched intravenous immunoglobulin (IVIG) may prevent or mitigate…
- Trial name
- CIPNM (NCT01867645)
- Testing
- IgM-enriched Intravenous Immunoglobulins, Human Albumin
- Where
- Austria
- Volunteers
- 38 people
- Sponsor
- Medical University of Vienna
Healthy Volunteer
A Trial to Learn if Single Ascending Intravenous (IV) Doses of REGN7508 Are Safe and Well Tolerated, and How it Works in the Body of Healthy Adult Participants
This study is researching an experimental drug called REGN7508 (called "study drug"). The aim of this study is to see how safe and tolerable the study drug is in healthy participants.
- Trial name
- NCT05603195
- Testing
- REGN7508 (IV), REGN7508 (SC)
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Allogeneic Stem Cell Transplantation
Study Comparing Valganciclovir Versus Ganciclovir in Patients Following Allogeneic Stem Cell Transplantation
The objective of this study is to assess the efficacy and safety of oral valganciclovir versus intravenous ganciclovir in patients following allogenic stem cell transplantation.
- Trial name
- CONVINCE (NCT01185223)
- Testing
- Valganciclovir, Ganciclovir
- Where
- 17 sites in Austria, Germany and 1 more
- Volunteers
- 212 people
- Sponsor
- Pierrel Research Europe GmbH
Healthy
Bioavailability Study of MLDL1278A After Subcutaneous and Intravenous Administration in Healthy Subjects
This is a study in healthy volunteers designed to investigate the PK following intravenous and subcutaneous administration of MLDL1278A (also known as BI-204).
- Trial name
- NCT01486823
- Testing
- MLDL1278A
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- BioInvent International AB
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