Clinical trials: Intravenous
Hemodialysis Complication, Anemia
Intravenous Versus Oral Iron Therapy in Hemodialysis Patients
This study is aim to compare the efficacy of intravenous versus oral iron therapy regarding the hemoglobin levels, iron status and erythropoietin dosage in maintenance hemodialysis patients
- Conditions
- Hemodialysis Complication, Anemia, Iron Deficiency Anemia
- Trial name
- IVO-IRON (NCT04464850)
- Testing
- Intravenous iron, Oral iron
- Where
- Thailand
- Volunteers
- 124 people
- Sponsor
- Chiang Mai University
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory Pneumonitis
This phase II trial studies how well infliximab and intravenous immunoglobulin therapy work in treating patients with pneumonitis that does not respond to steroid treatment.
- Conditions
- Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Steroid-Refractory Pneumonitis
- Trial name
- NCT04438382
- Testing
- Infliximab, Intravenous Immunoglobulin Therapy, Prednisone
- Where
- 18 sites in United States
- Volunteers
- 1 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Influenza, Flu
A Phase 1, Open Label, Ascending Dose Cohort Study of the Pharmacokinetics of Anti-Influenza Hyperimmune Intravenous Immunoglobulin in Healthy Subjects
Despite currently available antivirals, influenza causes significant morbidity and mortality, with 226,000 excess hospitalizations and 30,000-50,000 deaths each year in the United States alone, and more therapies are needed in…
- Trial name
- NCT02037282
- Testing
- Anti-influenza IVIG
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cancer
A Study of Telemonitoring in Cancer Patients
The goal of this prospective, randomized, unblinded, single-centre, interventional study is to assess the effectiveness of standard of care with Cureety, compared to standard of care alone, to reduce the number of all telephone…
- Trial name
- MINERVA (NCT06381024)
- Testing
- remote patient monitoring
- Where
- France
- Volunteers
- 86 people
- Sponsor
- Centre Hospitalier de Bligny
Alzheimer´s Disease
Long-Term Study of IGIV, 10% in Alzheimer´s Disease
The purpose of this long-term study is to provide additional evidence of safety and efficacy of IGIV, 10% treatment in participants with Alzheimer´s Disease who have completed the Phase 3 Baxter precursor study 160701.
- Trial name
- NCT01736579
- Testing
- Immune Globulin Intravenous (Human), 10% (IGIV, 10%)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Baxalta now part of Shire
Postoperative Pain
Nalbuphine as an Adjuvant to Intravenous Regional Anesthesia
The effect of addition of nalbuphine to lidocaine in intravenous regional anesthesia
- Trial name
- NCT02678585
- Testing
- Nalbuphine, Lidocaine
- Where
- Egypt
- Volunteers
- 106 people
- Sponsor
- Assiut University
Healthy
Study of LY3039478 in Healthy Participants
The study involves one dose of LY3039478 given by mouth followed by an intravenous infusion (IV) (via a tube linked to a small needle in the vein) of LY3039478.
- Trial name
- NCT02906618
- Testing
- LY3039478, 13C 15N 2H-LY3039478 IV
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Leiomyoma, Uterine, Intraoperative Blood Loss
Intravenous Tranexamic Acid and Intramyometrial Desmopressin Effect on Blood Loss During Laparoscopic Myomectomy.
To evaluate the effect of intravenous tranexamic acid plus intramyometrial desmopressin administration on perioperative blood loss and blood transfusion need in laparoscopic myomectomy operation.
- Trial name
- NCT05517590
- Testing
- Tranexamic acid, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Myelodysplastic Syndromes and Leukemia, Myeloid, Acute
Decitabine, Arsenic Trioxide and Ascorbic Acid for Myelodysplastic Syndromes and Acute Myeloid Leukemia
This study is designed to test the combination of decitabine, arsenic trioxide and ascorbic acid in patients with myelodysplastic syndromes (MDS) and acute myeloid leukemia
- Trial name
- NCT00671697
- Testing
- Arsenic Trioxide, Decitabine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Washington University School of Medicine
Healthy Volunteers
A Study to Assess Safety, Tolerability, Pharmacokinetics (PK), Immunogenicity, and Pharmacodynamics (PD) of Intravenous Infusions of E2814 in Healthy Participants
The primary objective of this study is to evaluate the safety and tolerability of single and multiple intravenous infusions of E2814 in healthy adult participants.
- Trial name
- NCT04231513
- Testing
- E2814
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Elderly, Orthopedic Surgery
Dexmedetomidine Supplemented Intravenous Analgesia in Elderly After Orthopedic Surgery
Delirium is common in the elderly after orthopedic surgery and is associated with worse outcomes. The investigators hypothesize that, for elderly patients after orthopedic surgery, dexmedetomidine supplemented intravenous…
- Conditions
- Elderly, Orthopedic Surgery, Analgesia, Dexmedetomidine
- Trial name
- NCT03629262
- Testing
- Dexmedetomidine
- Where
- 2 sites in China
- Volunteers
- 712 people
- Sponsor
- Peking University First Hospital
Pain
Comparison of Tramadol Orally Versus an Optimized Dose of Intravenous Tramadol for Postoperative Pain Relief in Ambulatory Surgery
The purpose of this study is to compare the administration of 1 unit dose of 50 mg tramadol perorally given in 3 unit dosages versus tramadol IV given in 3 unit dosage of 35 mg during the first 6 hours postoperatively and to…
- Trial name
- NCT00735748
- Testing
- Tramadol per os (Tradonal Odis® orodispersible tablets), Tramadol IV (Tradonal® IV)
- Where
- Belgium
- Volunteers
- 195 people
- Sponsor
- University Hospital, Ghent
Skeletal Muscle Relaxation
A Phase I Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenous Bolus and Infusion HRS-9190 in Healthy Adults
This study is divided into two parts. The first part adopts a single-center, randomized, single-blind, placebo-controlled dose escalation trial design to investigate the safety, tolerability, pharmacokinetics (PK), and effects on…
- Trial name
- NCT07142850
- Testing
- HRS-9190
- Where
- China
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Thrombosis
Safety and Tolerability Study of E-WE Thrombin in Healthy Adult Subjects
The purpose of this study is to assess the safety, tolerability and pharmacodynamics of a single iv dose of E-WE Thrombin in healthy adult subjects.
- Trial name
- NCT03453060
- Testing
- E-WE Thrombin- Dose 1, E-WE Thrombin- Dose 2, E-WE Thrombin- Dose 3
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Aronora, Inc.
Acinetobacter Baumannii Infection
Evaluation of the Safety, Tolerability and Pharmacokinetics of Intravenous ETX2514 Administered in Healthy Subjects
This research project is being conducted to look at the safety, tolerability, and pharmacokinetics (PK; how the human body processes a substance) of ETX2514 when given to healthy volunteers intravenously as a single dose, and…
- Trial name
- NCT02971423
- Testing
- ETX2514, Sulbactam, Imipenem/Cilastatin
- Where
- Australia
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Entasis Therapeutics
Heart Failure
Evaluate the Safety and Efficacy of 48-Hour Infusions of HNO (Nitroxyl) Donor in Hospitalized Patients With Heart Failure
A Study to Evaluate Safety and Efficacy of Continuous 48-Hour Intravenous Infusions of HNO Donor in Hospitalized Patients with Heart Failure and Impaired Systolic Function
- Trial name
- STANDUP AHF (NCT03016325)
- Testing
- HNO Donor
- Where
- 116 sites in United States, Argentina and 11 more
- Volunteers
- 329 people
- Sponsor
- Bristol-Myers Squibb
Abortion in First Trimester
Intravenous Ketamine for Pain Control During First Trimester Surgical Abortion
A therapeutic abortion is one of the most common procedures performed in Canada, with approximately 100,000 occurring annually. 95% of induced abortions are done surgically, with just over two thirds of these procedures taking…
- Trial name
- NCT03751423
- Testing
- PO Morphine, IV Fentanyl, IV Ketamine
- Where
- Canada
- Volunteers
- 123 people
- Sponsor
- Dr. Marie Eve Sophie Bussiere-Cote
Cross Infection, Pneumonia, Bacterial
Intravenous Colistin Versus Intravenous Colistin Plus Nebulized Colistin in VAP Due MDR Acinetobacter Baumannii
Compare the clinical efficiency evaluated by the treatment of the intravenous colistin plus inhaled colistin opposite to the treatment with colistin intravenous plus inhaled saline solution in patients with VAP due to baumannii…
- Trial name
- NCT00645723
- Testing
- Colistin, Colistin and saline solution
- Where
- Spain
- Volunteers
- 67 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Adult Rhabdomyosarcoma, Childhood Alveolar Rhabdomyosarcoma
Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma
This randomized phase II trial studies how well vinorelbine tartrate and cyclophosphamide work in combination with bevacizumab or temsirolimus in treating patients with recurrent or refractory rhabdomyosarcoma.
- Conditions
- Adult Rhabdomyosarcoma, Childhood Alveolar Rhabdomyosarcoma, Childhood Pleomorphic Rhabdomyosarcoma, Childhood Rhabdomyosarcoma With Mixed Embryonal and Alveolar Features
- Trial name
- NCT01222715
- Testing
- Bevacizumab, Cyclophosphamide, Laboratory Biomarker Analysis
- Where
- 184 sites in United States, Australia and 2 more
- Volunteers
- 87 people
- Sponsor
- National Cancer Institute (NCI)
Anemia, Colorectal Neoplasm
IVICA: Intravenous Iron in Colorectal Cancer Associated Anaemia
116 eligible patients with confirmed non-metastatic colorectal adenocarcinoma and anemia will be randomized to receive either oral ferrous sulphate (control) or intravenous ferric carboxymaltose (intervention).
- Trial name
- IVICA (NCT01701310)
- Testing
- Ferric carboxymaltose, Ferrous Sulphate
- Where
- 8 sites in United Kingdom
- Volunteers
- 116 people
- Sponsor
- Nottingham University Hospitals NHS Trust
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