Clinical trials: Intravenous Injections
Hepatitis C, HIV Infections
Study to Reduce Intravenous Exposures (STRIVE)
The purpose of this study is to determine whether a six-session, small group behavioral intervention based on "peer-volunteer activism" is effective in (1) decreasing distributive sharing of syringes and other injection…
- Trial name
- NCT00391482
- Testing
- Peer Mentoring Intervention for HCV-Infected IDUs
- Where
- 3 sites in United States
- Volunteers
- 750 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Healthy Volunteers
Multiple-dose Study of Levetiracetam Injection in Japanese and Caucasian Healthy Males
To compare the pharmacokinetics of levetiracetam following single and multiple 15-minute intravenous infusions of 1500 mg levetiracetam between Japanese and Caucasian healthy male subjects
- Trial name
- NCT01725009
- Testing
- Multiple 15-minute intravenous infusions of 1500 mg levetiracetam
- Where
- Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- UCB Japan Co. Ltd.
T-cell Lymphoma, Virus
Intravenous Injection of Oncolytic Virus Injection (RT-01) in Patients With Relapsed or Refractory T-cell Lymphoma
This is a single-arm, open-label, clinical pharmacology study to evaluate safety and efficacy of oncolytic virus injection(RT-01) in patients with Relapsed or Refractory T-cell Lymphoma.
- Conditions
- T-cell Lymphoma, Virus, Intravenous Injection
- Trial name
- NCT05387226
- Testing
- Oncolytic Virus Injection(RT-01)
- Volunteers
- 6 people
- Sponsor
- The First Affiliated Hospital of Bengbu Medical University
Parenteral Nutrition
A Bioequivalence Study Comparing Organic Phosphate (Sodium Glycerophosphate Injection) to Inorganic Phosphate (Sodium Phosphates Injection, USP)
This is a phase 1, prospective, single-center, randomized sequence, double-blind, 2-way crossover, relative bioavailability study in healthy adult subjects comparing Sodium Glycerophosphate Injection (SGP) to Sodium Phosphate…
- Trial name
- NCT06842121
- Testing
- Sodium Glycerophosphate Injection, Sodium Phosphates Injection
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Baxter Healthcare Corporation
Shoulder Arthroplasty, Postoperative Pain
Superior Trunk Block Catheter Versus Single-shot Superior Trunk Block With Intravenous Dexmedetomidine for Shoulder Arthroplasty
Shoulder arthroplasty is associated with significant postoperative pain. Appropriate pain control after shoulder arthroplasty is crucial for postoperative rehabilitation and patient satisfaction.
- Trial name
- NCT05020821
- Testing
- Single-shot superior trunk block with intravenous dexmedetomidine, Continuous superior trunk block
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Yonsei University
Infertility Due to Nonimplantation
Effect Of Intravenous IntralipidTherapyon Pregnancy Outcome in Women With History of Recurrent Implantation Failure Undergoing Intracytoplasmic Sperm Injection-Embryo Transfer Cycle: A Randomized Controlled Trial
To evaluate the effect ofempiricintralipidinfusion therapy on pregnancy outcomes in patient withunexplained recurrentimplantation failure (RIF) undergoIntracytoplasmic sperm injection (ICSI).
- Trial name
- NCT03374163
- Testing
- intralipid 20%
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
Neoplasms
BIBW 2992 (Afatinib) and Vinorelbine in Japanese Patients With Advanced Solid Tumours
To identify the Maximum Tolerated Dose (MTD) of afatinib in combination with vinorelbine i.v. by assessment of Dose Limiting Toxicities (DLT); To assess safety and anti-tumour efficacy and determine pharmacokinetic…
- Trial name
- NCT01214616
- Testing
- afatinib 20mg, afatinib 40mg, vinorelbine IV 25 or 20mg/m2
- Where
- 4 sites in Japan
- Volunteers
- 17 people
- Sponsor
- Boehringer Ingelheim
Systemic Lupus Erythematosus
BENLYSTA® Special Drug Use Investigation
The objective of this study is to collect and assess the information about long-term safety and effectiveness of Benlysta for intravenous injection and Benlysta for subcutaneous injection (hereinafter referred to as "Benlysta")…
- Trial name
- NCT03370263
- Testing
- Benlysta
- Where
- Japan
- Volunteers
- 1,514 people
- Sponsor
- GlaxoSmithKline
Cryptosporidiosis, HIV Infections
A Study of Spiramycin in the Treatment of Patients With AIDS-Related Diarrhea
To determine the safety and effectiveness of intravenous spiramycin in patients with AIDS-related cryptosporidial diarrhea. Spiramycin, a macrolide antibiotic, has been studied in the United States for the treatment of…
- Trial name
- NCT00000980
- Testing
- Spiramycin
- Where
- 7 sites in United States
- Volunteers
- 25 people
- Sponsor
- Rhone-Poulenc Rorer
Pain
Effect of Intravenous Lidocaine, Used to Attenuate Pain With Propofol Injection, on Defibrillation Threshold Testing
The use of lidocaine, as an anesthetic drug, during implantation of an implantable cardioverter-defibrillator(ICD)will not result in a clinically significant alteration of the defibrillation threshold during ICD placement.
- Trial name
- NCT03117166
- Testing
- lidocaine
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Drexel University College of Medicine
Central Nervous System Pathology
Study to Find the Appropriate Dose of a New Gadolinium-based Contrast Agent (GBCA) for Adults Undergoing Magnetic Resonance Imaging (MRI) for Known or Highly Suspected Brain and/or Spinal Cord Conditions
Researchers in this study want to find the appropriate dose of drug BAY1747846 for adults undergoing MRI for known or highly suspected brain and/or spinal cord conditions so that the image quality is similar to that of drug…
- Trial name
- NCT04307186
- Testing
- Gadoquatrane (BAY1747846), Gadobutrol (Gadovist/Gadavist)
- Where
- 17 sites in United States, Bulgaria and 2 more
- Volunteers
- 57 people
- Sponsor
- Bayer
Pain
Jet Injection of 1% Buffered Lidocaine Versus Topical ELA-Max for Anesthesia Prior to Intravenous (IV) Catheterization in Children
This trial is a comparison of the anesthetic effectiveness of J-Tip needle-free jet injection of 1% buffered lidocaine to the anesthetic effectiveness of topical 4% ELA-Max for peripheral intravenous catheter (PIV) insertion.
- Trial name
- NCT00444756
- Testing
- J-tip jet injection of 1% buffered lidocaine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Norton Healthcare
Chronic Calculous Cholecystitis, Laparoscopic Cholecystectomy
Using Indocyanine Green (ICG) to Outline Biliary Tree During Laparoscopic Cholecystectomy
The current study shows that Indocyanine green (ICG)-fluorescence cholangiography can be useful in identifying the extrahepatic biliary anatomy during Calot's triangle dissection.
- Trial name
- ICG (NCT06629415)
- Testing
- Indocyanine Green, Indocyanine Green Drug
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Theodor Bilharz Research Institute
Intravenous Drug Abuse, HIV Infections
Reducing Health Problems Associated With Injection Drug Use
The purpose of this study is to develop and test an intervention to reduce bacterial and viral infections among injection drug users.
- Trial name
- NCT01128920
- Testing
- Skin and Needle Hygiene Intervention, No intervention - assessment-only condition
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Northern Colorado
HIV Infections
A Study of BMY-27857 in Patients With AIDS or AIDS Related Complex
To evaluate the safety, minimum effective dose (MED), pharmacokinetics and efficacy of orally administered 2',3'-dideoxy-2',3'-didehydrothymidine (d4T) in patients with AIDS or AIDS related complex (ARC).
- Trial name
- NCT00000988
- Testing
- Stavudine
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pain on Propofol IV Injection
In Children, Does Using a Synera Patch Decrease Pain When Injecting Propofol at Anesthesia Induction?
The purpose of this study is to evaluate if the Synera Patch (lidocaine/tetracaine patch), used to numb the skin before IV placement, is effective in reducing pain associated with propofol IV administration when inducing general…
- Trial name
- Synera patch (NCT01576770)
- Testing
- lidocaine/tetracaine transdermal patch (NDC 43469-864-01), Gebauer's Ethyl Chloride
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center, Houston
Advanced Solid Tumor
RT-01 Monotherapy and in Combination With Nivolumab in Patients With Advanced Solid Tumors
This is a single-arm, open-lable study to determine the safety, tolerability and preliminary efficacy of oncolytic virus injection (RT-01) combined with or without immune checkpoint inhibitors (Nivolumab) in the treatment of…
- Trial name
- NCT05122572
- Testing
- Oncolytic Virus Injection (RT-01）
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Wuxi People's Hospital
Uterine Fibroid
Evaluating Efficacy of Intravenous Carbetocin Versus Intramyometrial Injection of Adrenaline in Reducing Blood Loss
Uterine fibroids, affecting 20-50% of all women ,and are benign tumors that arise from myometrial cells of the uterine smooth muscle tissue.
- Trial name
- NCT05986266
- Testing
- Carbetocin
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Egymedicalpedia
Lymphoma, B-cell, Diffuse
Phase I/II Study of SyB L-0501RI in Combination With Rituximab to Treat Lymphoma
For SyB L-0501RI administered by an intravenous rapid infusion in combination with rituximab, the safety will be investigated in previously untreated patients with low-grade B-cell non-Hodgkin's lymphoma (Lg-B-NHL) or mantle cell…
- Trial name
- NCT03900377
- Testing
- SyB L-0501RI
- Where
- 14 sites in Japan
- Volunteers
- 37 people
- Sponsor
- SymBio Pharmaceuticals
Pulmonary Disease, Chronic Obstructive
A Study To Investigate Safety, Blood Levels And Effects Of Giving GW642444, By Mouth, By Inhalation & By Injection
This study will involve the use of a new medicine called GW642444 being developed for the treatment of asthma and chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00711126
- Testing
- GW642444
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline