Clinical trials: Intravenous Injections, open to volunteers
Protein C Deficiency
A Study of Freeze-dried Human Protein C Concentrate (TAK-662) in Participants With Congenital Protein C Deficiency
This study is conducted in Japan of Freeze-dried Human Protein C Concentrate (TAK-662) used to treat participants with congenital protein C deficiency.
- Trial name
- NCT06590974
- Testing
- Freeze-dried Human Protein C Concentrate
- Where
- Japan
- Volunteers
- 7 people
- Sponsor
- Takeda
Post-Dural Puncture Headache
Prophylactic Intravenous Injection of Neostigmine Plus Atropine Versus Ketorolac on Post-dural Puncture Headache in Patients Undergoing Infraumbilical Surgeries
Post-dural puncture headache (PDPH) or spinal (or post-spinal) headache is one of the most common side effects of spinal anesthesia, with an incidence of 6-36%.
- Trial name
- NCT06729047
- Testing
- normal Saline, Neostigmine, Ketorolac
- Where
- Egypt
- Volunteers
- 330 people
- Sponsor
- Assiut University
Alzheimer's Disease
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of SHR 3201 Injection in Healthy Participants
This study is a randomized, double-blind, dose-escalation, placebo-controlled Phase I clinical trial in healthy participants to evaluate the safety, tolerability, and pharmacokinetics of single intravenous and subcutaneous…
- Trial name
- NCT07889349
- Testing
- SHR 3201 Injection
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Beijing Suncadia Pharmaceuticals Co., Ltd
Advanced Solid Tumors
A Study of the Safety and Efficacy of the Intravenous and Intratumoral Injection of OVV-01 in Patients With Advanced Solid Tumours.
This is an open-label, single-arm, dose escalation clinical study to evaluate the safety and preliminary efficacy of OVV-01 Injection in patients with advanced solid tumors, following both intravenous (iv.) and intratumoral (it.)…
- Trial name
- NCT07648472
- Testing
- OVV-01 Injection
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Joint Biosciences Ltd.
Crigler-Najjar Syndrome
Gene Therapy for Severe Crigler Najjar Syndrome
This is a Phase 1/2, multinational, open-label, study to evaluate the safety and efficacy of an intravenous infusion of GNT0003 in patients with Crigler-Najjar aged ≥10 years and requiring phototherapy.
- Trial name
- CareCN (NCT03466463)
- Testing
- GNT0003
- Where
- 4 sites in France, Italy and 1 more
- Volunteers
- 17 people
- Sponsor
- Genethon
Healthy Volunteers (HV)
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of KR25102 in Healthy Volunteers
Phase 1 Single Ascending Doses(SAD): Six cohorts of 53 healthy volunteers (HVs) will receive a single IV bolus injection of study drug or placebo.
- Trial name
- NCT07618156
- Testing
- KR25102 for Injection
- Where
- China
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Jiangxi Kvvit Pharmaceutical Co., Ltd.
Procedural Pain
Intravenous Nalbuphine Versus Lidocaine for Prevention of Propofol Injection Pain
Propofol is a commonly used intravenous anesthetic agent, but its administration is frequently associated with injection pain, causing patient discomfort and agitation.
- Trial name
- NCT07422558
- Testing
- Nalbuphine, Lidocaine
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Hayatabad Medical Complex
Advanced Solid Tumors
OVV-01 Intravenous and Intratumoral Injection Combined With AK112 for the Treatment of Advanced Solid Tumors
This study is an open-label, multiple-route-of-administration dose-escalation clinical trial designed to evaluate the safety and preliminary efficacy of OVV-01 injection administered intravenously or intravenously plus…
- Trial name
- NCT07650825
- Testing
- OVV-01, AK112
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Nurse Education, Intravenous Catheters
The Effect of Intravenous Injection Training Based on the ARCS-V Model on Levels of Learning Motivation and Self-Efficacy
Intravenous (IV) administration, one of the most fundamental and common practices carried out by nurses, is defined as the administration of medication directly into the circulatory system via a vein.
- Conditions
- Nurse Education, Intravenous Catheters, INTRAVENOUS CATHETER APPLICATION, Intravenous Therapy
- Trial name
- NCT07691983
- Testing
- ARCS-V Model Teaching
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Healthy Participants, Ulinastatin
Pharmacokinetics, Safety and Tolerability of Single Sequential and Multiple Intravenous Infusions of Ulinastatin for Injection in Healthy Chinese Participants
This is a Phase 1 clinical study. The purpose of this study is to evaluate the pharmacokinetics, safety and tolerability of ulinastatin for injection after single sequential and multiple continuous intravenous infusions in…
- Trial name
- NCT07923578
- Testing
- Ulinastatin
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Techpool Bio-Pharma Co., Ltd.
Trauma Injury
IV Injection of Metoclopramide With or Without Dexamethasone
Reflux and the aspiration of gastric contents have always been important focal points. Previous study stated that trauma is an important factor in aspiration pneumonia.
- Trial name
- NCT07343817
- Testing
- Dexamethasone, Ultrasonography assessment
- Volunteers
- 1 people
- Sponsor
- Ahmed Nassar Ibrahim Mohammed
Tonsillectomy
Comparsion of Intravenous Injection of Magnesium Sulfate and Lidocaine Effectiveness on the Prevention of Laryngospasm and Analgesic Requirement in Tonsillectomy
Tonsillectomy is one of the most common surgeries in children which is associated with many morbidities such as postoperative pain, nausea, vomiting, bleeding and laryngospasm .
- Trial name
- NCT06761547
- Testing
- magnsium sulfate, Lidocaine (drug), Saline
- Volunteers
- 90 people
- Sponsor
- Assiut University