Clinical trials: Intravenous Therapy
Multiple Sclerosis
Efficacy Study of Adrenocorticotropin Hormone to Treat Multiple Sclerosis (MS) Relapses After Sub-responding to an Initial 3 Day Course of Intravenous (IV) Methylprednisolone
The purpose of this study is to compare intramuscular (IM) ACTH (adrenocorticotropin hormone) and intravenous (IV) methylprednisolone (Solumedrol) for the treatment of an MS (Multiple Sclerosis) relapse (exacerbation) after…
- Trial name
- RECLAIM (NCT00947895)
- Testing
- Methylprednisolone, ACTH
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Neurologique Foundation, Inc.
Bacterial Pneumonia
Cx611-0204 SEPCELL Study
The purpose of this randomised, multicentre, double-blind, placebo-controlled, phase Ib/IIa study is to assess the safety, tolerability and efficacy of eASCs (Cx611) administered intravenously as adjunctive therapy, therefore in…
- Trial name
- SEPCELL (NCT03158727)
- Testing
- Cx611
- Where
- 33 sites in Belgium, France and 4 more
- Volunteers
- 84 people
- Sponsor
- Tigenix S.A.U.
Staphylococcal Infections
Vancomycin Study: Treatment of Catheter Related Bloodstream Infection Caused by Coagulase Negative Staphylococcus
Patients admitted into the Intensive Care Unit (ICU) have an intravenous (IV) catheter (small plastic tube) placed in their vein.
- Trial name
- NCT00175370
- Testing
- Vancomycin
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Pemphigus
IVIG With Rituximab vs Rituximab as First Line Treatment of Pemphigus
Pemphigus is a rare acquired autoimmune disease in which immunoglobulin G (IgG) antibodies target desmosomal proteins to produce intraepithelial, and mucocutaneous blisters.
- Trial name
- NCT04400994
- Testing
- Rituximab, IVIg
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- The University of Hong Kong
Fibromyalgia
Intravenous Micronutrient Therapy (IVMT) for Fibromyalgia
The purpose of this study is to determine if intravenous micronutrient therapy (IVMT) is effective in the treatment of fibromyalgia, as assessed by validated functional and pain measures.
- Trial name
- NCT00067405
- Testing
- Intravenous micronutrient therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Intravenous Drug Abuse, Chronic Hepatitis C
Psychoeducation Reaches HCV-infected Methadone/Buprenorphine Substituted Patients in Standard Antiviral Treatment
Study objective: Feasibility and efficacy of a standardised psychosocial intervention (psychoeducation) in substituted opioid dependent patients
- Trial name
- Permit (NCT00844272)
- Testing
- Psychoeducation
- Volunteers
- 189 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Amyotrophic Lateral Sclerosis
Safety and Efficacy of Intravenous Administration of SHED-CM for ALS
This study evaluates the safety and efficacy of Stem Cell from Human Exfoliated Deciduous teeth Conditioned Media (SHED-CM) in patients with Amyotrophic Lateral Sclerosis (ALS), using the Japanese version of the revised ALS…
- Trial name
- SCA202401 (NCT06889857)
- Testing
- The study drug is SHED-CM manufactured by U-Factor
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- Hitonowa Medical
Post-Traumatic Stress Disorders, Major Depressive Disorder
Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans
Co-occurring post-traumatic stress disorder (PTSD) and major depressive disorder (MDD) is the most common response to trauma; it is associated with poor clinical outcomes and substantial human disability.
- Trial name
- NCT04032301
- Testing
- Ketamine, Normal Saline
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Preeclampsia
A Study of Cerebral-circulatory Response to Intravenous Antihypertensive Treatment in Women With Serious Preeclampsia
The purpose of this study is a systematical registration of hemodynamic measurements (cardiac output, blood pressure and systemic vascular resistance) in women with serious preeclampsia.
- Trial name
- NCT00403572
- Volunteers
- 8 people
- Sponsor
- Oslo University Hospital
Cerebral Malaria
Efficacy of Intrarectal Versus Intravenous Quinine for the Treatment of Childhood Cerebral Malaria
Cerebral malaria is the most lethal complication of P.falciparum infection with a mortality rate between 5 and 40%. Intravenous quinine remains the recommended treatment for cerebral malaria.
- Trial name
- NCT00124267
- Testing
- Intrarectal quinine
- Where
- Uganda
- Volunteers
- 108 people
- Sponsor
- Makerere University
Transplantation:Mesenchymal Stem Cell Transplantation
Parkinson's Disease Therapy Using Cell Technology
Treatment of patients with Parkinson's disease using mesenchymal stem cells is a perspective method to influence on the pathogenesis of the disease. At the same time, this is a complex and still insufficiently explored process.
- Trial name
- NCT04146519
- Testing
- Autologous mesenchymal stem cells
- Where
- Belarus
- Volunteers
- 50 people
- Sponsor
- Belarusian Medical Academy of Post-Graduate Education
Colitis, Ulcerative
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Ulcerative Colitis (UC)
Vedolizumab is a medicine that helps to reduce inflammation and pain in the digestive system. In this study, children and teenagers with moderate to severe ulcerative colitis will be treated with vedolizumab.
- Trial name
- NCT04779307
- Testing
- Vedolizumab
- Where
- 65 sites in United States, Australia and 12 more
- Volunteers
- 121 people
- Sponsor
- Takeda
Urolithiasis
Intravenous Paracetamol or Morphine for the Treatment of Acute Flank Pain
STUDY OBJECTIVE: This randomized, controlled trial evaluates the analgesic efficacy and safety of intravenous single-dose paracetamol and morphine for the treatment of acute flank pain.
- Trial name
- NCT01318187
- Testing
- paracetamol, morphine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Pamukkale University
Chronic Hepatitis C
Therapy With Ledipasvir/Sofosbuvir in Patients With Genotype 1 HCV Infection Receiving Opiate Substitution Therapy
Patients with chronic hepatitis C that are under opiate substitution therapy are likely to have psychiatric comorbidities such as depression; hence an Interferon based therapy is contraindicated.
- Trial name
- NCT02638233
- Testing
- Sofosbuvir 400mg / Ledipasvir 90 mg (FDC)
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Wilhelminenspital Vienna
Small Cell Lung Cancer
Second-line Treatment in Patients With Small Cell Lung Cancer (SCLC)
The purpose of this study is to determine treatment efficacy and tolerability of second-line treatment in patients with small cell lung cancer comparing oral combinaison chemotherapy with intravenous combination chemotherapy.
- Trial name
- NCT00418743
- Where
- 24 sites in France
- Volunteers
- 138 people
- Sponsor
- Groupe Francais De Pneumo-Cancerologie
HIV, HIV Infections
A Trial to Compare Raltegravir Versus Nevirapine as Anchor Drug for HIV+ Chinese IDUs on Methadone Maintenance
This is a pilot randomized controlled Open-label trial to compare raltegravir and nevirapine as anchor Drug in combined antiretroviral therapy(ART) for ART-naive HIV+ Chinese injection drug users who are also on methadone…
- Trial name
- NCT01042652
- Testing
- Raltegravir
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Centers for Disease Control and Prevention, China
Primary Breast Cancer
Zoledronic Acid in the Treatment of Breast Cancer With Minimal Residual Disease in the Bone Marrow
Metastatic bone disease is an important prognostic factor for survival which will in median be close to two years after first diagnosis of osseous metastases.
- Trial name
- MRD-1 (NCT00172068)
- Testing
- Zoledronic acid + Calcium/Vitamin D
- Where
- 4 sites in Germany
- Volunteers
- 96 people
- Sponsor
- Novartis Pharmaceuticals
Iron Deficiency, Inflammatory Bowel Disease
Maintenance Treatment of Iron Deficiency in IBD Patients
The aim of this study is to evaluate the treatment of iron deficiency in IBD patients.
- Trial name
- FER-IBD-MAIN (NCT00810004)
- Testing
- Ferinject
- Where
- Russia
- Volunteers
- 245 people
- Sponsor
- Vifor Pharma
Acute Ischemic Stroke
Enoxaparin and/or Minocycline in Acute Stroke
The purpose of this study is to investigate whether enoxaparin, minocycline, or both medications in combination may help in recovery from acute stroke.
- Trial name
- NCT00836355
- Testing
- Enoxaparin, Minocycline
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Bipolar Disorder
Treatment Study of Bipolar Depression
The purpose of this study is to determine whether a single intravenous administration of an N-methyl-D-aspartate antagonist is safe and effective for the acute treatment of bipolar depression.
- Trial name
- NCT00947791
- Testing
- ketamine, midazolam
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
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