Clinical trials: Intrinsic Capacity
Osteoporosis, Sarcopenia
Comprehensive Risk Assessment and Prevention Plan of Osteoporosis and Sarcopenia for the Elderly Participating in Community-based Long-term Care Services
The purpose of this project is: 1. Provide the epidemiological data of the prevalence, incidence, and risk factors of osteoporosis and sarcopenia among the elderly in rural areas. 2.
- Conditions
- Osteoporosis, Sarcopenia, Frailty
- Trial name
- NCT05104034
- Testing
- Osteoporosis screening and treatment as needed, Sarcopenia, Exercise
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Frailty, Aging
Effect of Multicomponent Exercises VIVIFRAIL® in Older Adults
This study employs a randomized, controlled, paired, single-blind clinical trial design. The targeted demographic comprises individuals aged 60 and above.
- Conditions
- Frailty, Aging, Physical Disability
- Trial name
- NCT06271239
- Testing
- Intervention group (ViviFrail), Group Suggestions for a Healthy Life (CG)
- Where
- 4 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Sleep Quality, DNA Damage Repair Deficiency
Melatonin and DNA Damage Study
This research aims to determine if melatonin supplementation, through improvements in sleep quality, increases the ability to repair oxidative DNA damage and reduce lipid peroxidation levels among nightshift workers.
- Conditions
- Sleep Quality, DNA Damage Repair Deficiency, Oxidative Stress
- Trial name
- NCT03945955
- Testing
- Melatonin
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Chronic Kidney Disease (CKD)
Exercise and Monitoring With Post-Hospitalization Muscle Atrophy to Sustain Intrinsic Capacity and Strength
The aging Veteran population has more frequent inpatient hospitalization than non-Veterans. In addition, older Veterans have an inability to fully recover muscle mass and function after hospital-acquired weakness.
- Trial name
- EMPHASIS (NCT06607913)
- Testing
- Exercise
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- VA Office of Research and Development
Shoulder Pain, Sleep Quality
Effects of Respiratory Muscle Strengthening and Diaphragmatic Breathing on Shoulder Pain and Disability
The aim of the study is to investigate the effects of respiratory muscle strengthening and diaphragmatic breathing on pain levels, respiratory capacity and sleep quality in participants with shoulder pain and disability.
- Conditions
- Shoulder Pain, Sleep Quality, Lung Cavity, Pain Intensity
- Trial name
- NCT07885215
- Testing
- shoulder rehabilitation, respiratory muscle strengthening exercises and diaphragmatic breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Zonguldak Bulent Ecevit University
Healthy Aging, Healthspan
Sheba Healthspan Research Population (SHARP) Trial - Sheba Longevity Center Diagnostic and Intervention Protocol to Lower Biological Age in Older Adults
Background: Population aging is accelerating rapidly in Israel and worldwide, necessitating adaptation of the healthcare system and considering new approaches that serve the needs of older adult populations.
- Conditions
- Healthy Aging, Healthspan, Biological Age, Intrinsic Capacity
- Trial name
- SHARP (NCT07596576)
- Testing
- healthspan personalized protocol, Control
- Where
- Israel
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Obesity Hypoventilation Syndrome (OHS), Hypoventilation
Effects of Exercise Training on Exercise Capacity and Sleep Quality in Patients With Obesity Hypoventilation Syndrome
Obesity Hypoventilation Syndrome is defined as a combination of obesity (BMI ≥ 30 kg/m2) and daytime hypercapnia in arterial blood gas analysis (PaCO2 > 45 mmHg) without other pathologies that cause hypoventilation.
- Conditions
- Obesity Hypoventilation Syndrome (OHS), Hypoventilation, Obesity, Respiration Disorders
- Trial name
- NCT05398068
- Testing
- Exercises and Diet, Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Frailty
Feasibility and Usability of Intrinsic Capacity Monitoring With Eforto and Its Predictive Value for Health Outcomes in Older Community-dwelling Persons
In this study, 160 community-dwelling older adults (65 years and older) will be provided with an eforto® system to self-monitor their muscle fatigability and self-perceived fatigue for 2 consecutive days per week during 12 months…
- Trial name
- FORTO 2 (NCT05368337)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Aging
Healthy Aging Through Optimized Exercise
here is enormous variation in how individuals respond to exercise and understanding the factors that drive this variation will guide individualized exercise prescriptions to improve or maintain health into older age.
- Trial name
- HELIOS (NCT07093216)
- Testing
- Exercise
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obstructive Sleep Apnea (OSA), Exercise Snacks
Exercise Interventions in Obstructive Sleep Apnea Syndrome
Obstructive Sleep Apnea Syndrome (OSA) is a condition characterized by repeated pauses or reductions in breathing during sleep, which can negatively affect sleep quality, daytime functioning, and physical capacity.
- Conditions
- Obstructive Sleep Apnea (OSA), Exercise Snacks, Physical Activity, Circadian Rhythm
- Trial name
- NCT07634029
- Testing
- Aerobic Exercise Training, Exercise Snacking
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Istanbul University - Cerrahpasa
Physical Functional Performance, Psychological Health
Interactive Exergaming With Otago Exercise Program on Mobility in Community-Dwelling Older Adults
This clinical trial aims to evaluate the effectiveness of interactive exergaming combined with Otago Exercise Program on mobility among community-dwelling older adults aged 65 and above.
- Conditions
- Physical Functional Performance, Psychological Health, Physical Fitness, Mobility Limitation
- Trial name
- GAME-OEP (NCT06814678)
- Testing
- Interactive Exergaming with Otago Exercise Program, Control Group with Usual Care
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University
Healthy, Healthy Adult
Sleep-Assessment in Patients Between High Altitude HA vs. Sea Level LA in Healthy Individuals H
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on sleeping parameters by polygraphy in healthy individuals, who live permanently >2600m.
- Conditions
- Healthy, Healthy Adult, High Altitude Effects, High Altitude
- Trial name
- NCT07801950
- Testing
- Descent from 2850m to sea level and re-ascent back to 2850m
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Multiple Sclerosis
Cognitive Functions in Patients With Multiple Sclerosis
Approximately 65% of multiple sclerosis (MS) patients appear to have problems in their cognitive function. Long-term memory is one of the most frequently affected functions in MS patients.
- Trial name
- NCT03594357
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Gazi University
Virtual Reality, Congenital Diaphragmatic Hernia
Virtual Reality and Congenital Diaphragmatic Hernia
The study has been designed to investigate the effect of 12 weeks of using virtual reality based exercises on pulmonary functions, exercise capacity, functional performance, and quality of life in children with…
- Conditions
- Virtual Reality, Congenital Diaphragmatic Hernia, Children
- Trial name
- NCT05612503
- Testing
- Traditional physical therapy program, Virtual reality-based exercises
- Where
- Saudi Arabia
- Volunteers
- 52 people
- Sponsor
- Qassim University
Ageing, Disability
The Beijing Longitudinal Disability Survey in Community Elderly
The goal of this observational study is to establish the prospective cohort of the Beijing Longitudinal Disability Survey in Community Elderly (BLINDSCE) to explore the high-risk factors and preventive interventions for…
- Conditions
- Ageing, Disability, Cognitive Impairment, Frailty
- Trial name
- BLINDSCE (NCT06863727)
- Where
- China
- Volunteers
- 1,962 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing