Clinical trials: Intubation, Difficult
Airway Management, Intubation, Intratracheal
The Difficult Airway Management Trial: "The DIFFICAIR-Trial"
In general anesthetic the patient is deprived of his awareness and ability to breathe. It is therefore one of the most important tasks in anesthesia to ensure the patient's airway and breathing.
- Trial name
- DIFFICAIR (NCT01718561)
- Testing
- SARI
- Where
- 28 sites in Denmark
- Volunteers
- 76,058 people, healthy volunteers welcome
- Sponsor
- Hillerod Hospital, Denmark
Intubation; Difficult or Failed, Airway Complication of Anesthesia
Comparing Full vs. Partial Glottis View Using CMAC D-Blade Video Laryngoscope in Simulated Cervical Injury Patient
Direct laryngoscope requires proper alignment of the oro-pharyngeal-laryngeal axis to provide an optimal glottic view for intubation.
- Trial name
- NCT04833166
- Testing
- CMAC D-blade videolaryngoscope with full or partial glottic view
- Where
- Malaysia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Cardiac Arrest, Coma
Out-of-Hospital Intubation With Metal Single Use Laryngoscope Blades
New single use laryngoscope metal blades are available for intubation. This type of blade is safer than the reusable ones concerning the interhuman cross infection risk.
- Conditions
- Cardiac Arrest, Coma, Major Trauma, Respiratory Distress
- Trial name
- LAMETA (NCT00644722)
- Testing
- MacIntosh Green Lite (metal single use laryngoscope blades), MacIntosh Green Spec II (metal reusable laryngoscope blades)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Henri Mondor University Hospital
Difficult Airway Intubation, Airway Management During Operative Procedure
Comparison of Video Laryngoscopy and Conventional Laryngoscopy for Safe Intubation in Adult Thyroid Surgery Patients With Anticipated Difficult Airway
This clinical study is designed to compare two different techniques used for inserting a breathing tube (a process known as intubation) in adult patients undergoing thyroid surgery who are predicted to have a difficult airway.
- Trial name
- NCT07113171
- Testing
- Conventional Direct Laryngoscope, Video Laryngoscope
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sheikh Zayed Medical College
Intubation; Difficult or Failed
Standard Versus Hyperangulated Video Laryngoscopy Blades for Intubation in Neonates and Small Infants
The goal of this prospective randomized cross over clinical trial is to compare the difference in the percentage of glottic opening (POGO) between two different video laryngoscopy blades, the hyperangulated Cobalt blade and the…
- Trial name
- NCT05843565
- Testing
- Non-standard blade (NSB), Standard blade (SB)
- Where
- Lebanon
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Tracheal Intubation, Elective Surgery, Tracheal Diamater Measurement
Ultrasound Measurement of Skin-to-Epiglottis Distance for Prediction of Difficult Airway in Adult Patients
This prospective observational study aims to evaluate the predictive value of ultrasound-measured skin to epiglottis distance for difficult airway in adult patients undergoing elective or emergency procedures requiring airway…
- Conditions
- Tracheal Intubation, Elective Surgery, Tracheal Diamater Measurement, Ultrasound Evaluation of Airway
- Trial name
- NCT07609147
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Hacettepe University
Intubation;Difficult
Predictive Parameters for Difficult Tracheal Intubation Identification in Thyroid Surgery
Intubation manoeuvres in patients undergoing thyroid surgery might be challenging for anesthesiologist. Thyroid gland enlargement (goiter) or tissue fibrosis (neoplasms) could alter the physiologic anatomy of upper airways and…
- Trial name
- NCT03578601
- Testing
- Thyroid surgery
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Padova
Pediatric Anesthesia, Intubation;Difficult
Emergency Front of the NecK Access (eFONA) in Children
Study participants will be shown an illustrated training video demonstrating and explaining the RST. The video may be reviewed until the participant feels confident to perform procedure.
- Trial name
- eFONA (NCT03576352)
- Testing
- a rapid sequence tracheostomy (RST) on rabbit cadaver
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Airway Management
MGPOCUS Assisted Bronchoscopy in Difficult Endotracheal Intubation
Introduction Endoracheal intubation (ETI) is a crucial but risky procedure, especially among patients with suspected difficult endotracheal intubation (DTI).
- Trial name
- NCT05647174
- Testing
- MGPOCUS-assisted bronchoscope-guided intubation, Bronchoscope-guided intubation
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Peking Union Medical College Hospital
Intubation;Difficult
The Difficult Airway
Patients who are obese, as defined by a BMI ≥ 30 kg/m2 may be more difficult to intubate than non-obese patients. Traditional methods of airway assessment such as Mallampati score, mouth opening, and thyromental distance may not…
- Trial name
- NCT03671824
- Testing
- Measurements
- Where
- United States
- Volunteers
- 4,022 people
- Sponsor
- University of Texas Southwestern Medical Center
Intubation; Difficult
Miller Straight Blade vs Macintosh Blade
The purpose of this prospective open labeled randomized study was to compare the "laryngoscopic glottis view" as well as "ease of intubation" between the two blades in routine intubations in non-difficult airways.
- Trial name
- NCT02664532
- Testing
- Miller group, Macintosh group
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tata Main Hospital
Intubation; Difficult or Failed, Intubation Complication
Expert Consensus Statements for the Management of a Physiologically Difficult Airway Using the Delphi Method (PDADelphi)
The aim of this study is to review/identify the existing definition and management strategies for a physiologically difficult airway (PDA), to generate expert consensus on the various aspects of managing a patient with a PDA…
- Conditions
- Intubation; Difficult or Failed, Intubation Complication, Hemodynamic Instability, Critical Illness
- Trial name
- PDADelphi (NCT05762068)
- Testing
- Delphi procedure
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Failed or Difficult Intubation, Sequela, Intubation; Difficult
Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs
Advanced airway interventions are common high risk, high stakes events for children in intensive care units (ICU) and emergency departments (ED), with risk for life and health threatening consequences.
- Conditions
- Failed or Difficult Intubation, Sequela, Intubation; Difficult, Intubation Complication
- Trial name
- NEAR4KIDs (NCT02493478)
- Where
- 87 sites in United States, Australia and 9 more
- Volunteers
- 150,000 people
- Sponsor
- Children's Hospital of Philadelphia
Artificial Intelligence (AI), Difficult Intubation
THE ROLE OF ARTIFICIAL INTELLIGENCE TRAINED WITH PRE-MEASURED NUMERICAL DATA IN PREDICTION OF DIFFICULT INTUBATION
This study aims to develop an artificial intelligence (AI)-based model to predict difficult intubation in patients undergoing general anesthesia.
- Trial name
- NCT06961240
- Testing
- AI-Based Difficult Airway Prediction Model
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Kutahya Health Sciences University
Intubation;Difficult, Thoracic Diseases
Fiberoptic Bronchoscope of Double Lumen Tube and Single Lumen Tube in Patients With Semi-regid Neck Collar.
Many intrathoracic procedures demand optimal collapse of the operative lung to facilitate surgical exposure. Single-lung ventilation can be achieved using a double-lumen tube (DLT), a Univent tube, or an independent bronchial…
- Trial name
- NCT03392766
- Testing
- single lumen tube and bronchial blocker, double lumen tube
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Ajou University School of Medicine
Intubation;Difficult
Comparison of Endotracheal Intubation Over the Aintree With Fiberoptic Bronchoskop Via the I-gel and LMA Protector
Investigators aimed to compare the ease of use of the LMA protector and I-gel LMA for tracheal intubation with the Aintree catheter in our study.
- Trial name
- NCT03501602
- Testing
- LMA protector, I-gel LMA
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Difficult Intubation, Thoracic Surgery
Double Lumen Tube Positioning With Bonfils Fiberoptic Stylet: Prospective Observational Study in 30 Adult Patients
The aim of this prospective observational study is to evaluate the efficacy of Bonfils fiberoptic stylet to perform tracheal intubation with double lumen tube after failure of standard laryngoscopy in 30 adults patients scheduled…
- Trial name
- NCT03982745
- Testing
- bonfils
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Università Politecnica delle Marche
Difficult Airway, Difficult Intubation
LeHeR Maneuver vs Sniffing Position During Video Laryngoscopy in Predicted Difficult Airway
The left head rotation (LeHeR) maneuver, in which the head of the supine patient is rotated 45° to the left, is a simple, equipment-free technique proposed to improve the laryngeal view.
- Conditions
- Difficult Airway, Difficult Intubation, Video Laryngoscopy, Airway Management
- Trial name
- LeHeR-VL (NCT07902973)
- Testing
- Video laryngoscopy in the sniffing position, Left Head Rotation (LeHeR) maneuver
- Volunteers
- 40 people
- Sponsor
- Sakarya University
Intubation; Difficult or Failed, Anesthesia
Use of Point-of-View Camera to Faciliate Learning of Endotracheal Intubation
The study team proposes that mounting a point-of-view camera on the student's head will enable the team to view what the student is seeing in real-time when intubating with a normal laryngoscope.
- Trial name
- NCT04477044
- Testing
- Study Group
- Where
- Singapore
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Endotracheal Intubation
A Comparison of Tracheal Intubation Using the Totaltrack vs the Airtraq Laryngoscope in Difficult Airway Management
Endotracheal intubation is usually required to allow unrestricted surgical approach. The Macintosh laryngoscope is the standard method.
- Trial name
- NCT02395406
- Testing
- Orotracheal intubation with Totaltrack, Orotracheal intubation with Airtraq
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Manuel Ángel Gómez-Ríos