Clinical trials: Intubation
Acute Respiratory Failure
DirEct Versus VIdeo LaryngosCopE Trial
Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States.
- Trial name
- DEVICE (NCT05239195)
- Testing
- Video Laryngoscope, Direct Laryngoscope
- Where
- 12 sites in United States
- Volunteers
- 1,420 people
- Sponsor
- Vanderbilt University Medical Center
Supraglottic Airway
AMBU AScope2 Fiberoptic Intubation Versus Fastrach Intubating LMA
The purpose of this study is to compare two types of supraglottic airways (SGA), the Ambu® Aura-I and the Intubating Laryngeal Mask Airway (ILMA), regarding time to intubate, ease of insertion, sealing properties, optical view…
- Trial name
- NCT01656967
- Testing
- AMBU Aura-I/aScope 2, LMA Fastrach Single Use
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Tracheal Intubation, Laryngoscopy
Force and Pressure Distribution Using Macintosh and GlideScope Laryngoscopes in Normal Airway: an in Vivo Study
Forces applied on soft upper tissues by different laryngoscope blades during direct laryngoscopy and intubation are considered to be major stimuli to cause serious damages to the patients.
- Trial name
- NCT01685320
- Testing
- Forces applied by laryngoscope
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Campus Bio-Medico University
Intubation; Difficult
Initial Experience With Storz C-MAC Video Intubation System
The purpose of this study is to determine the safety and efficacy of the C-MAC (Karl Storz Endoscopy, Inc., Tuttlingen, Germany) video intubation system guided intubation techniques.
- Trial name
- C-MAC (NCT01104090)
- Testing
- C-MAC direct laryngoscopy, C-MAC Indirect laryngoscopy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Critically Ill Patients
Esketamine Induction Intubation in ICU Patients.
Intubation in the intensive care unit (ICU) is usually an emergency. Pathophysiological changes such as shock, respiratory failure, and metabolic acidosis in critically ill patients can significantly increase the incidence of…
- Trial name
- NCT05464979
- Testing
- Esketamine Hydrochloride 28 Mg in 0.2 mL NASAL SOLUTION [Spravato], midazolam, fentanyl
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Obesity
Pentax Airway Scope (AWS) Intubation
This study will compare the Macintosh laryngoscope with the Pentax. The Pentax AWS is a novel airway management device that is designed to facilitate laryngoscopy and endotracheal intubation.
- Trial name
- NCT00667693
- Testing
- Macintosh laryngoscope, Pentax AWS
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- The Cleveland Clinic
Airway Control
Observational Study of Rapid Sequence Intubation Drug Delivery Using Intraosseous and Intravenous Access.
This study will evaluate using intraosseous vascular access and intravenous vascular access to give patients the necessary medications to perform rapid sequence intubation, for patients with airway difficulties.
- Trial name
- NCT01486407
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Vidacare Corporation
Obesity
Comparative Effectiveness of Intubating Devices in the Morbidly Obese
This prospective, randomized study will compare the effectiveness of 4 different airway intubating devices which are most commonly used.
- Trial name
- NCT01114945
- Testing
- McGrath, GlideScope, Direct Macintosh Laryngoscopy
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Cedars-Sinai Medical Center
Obesity
Study Examining Parker-Flex Endotracheal Tube for Obese Patients
A recent article examined the use of Parker Flex-Tip tubes to standard ETTs for oral fiberoptic intubation and concluded that there was a significant benefit in terms of difficulty encountered when using the Parker Flex-Tip.
- Trial name
- NCT01894178
- Testing
- Parker Flex-Tip® tracheal tube, Portex® Tracheal Tube
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Surgeries Undergoing General Anesthesia
Study: Study to Compare Video Miller Device to Direct Laryngoscopy
The purpose of this study is to compare: the standard pediatric intubation instrument (Miller blade) used as direct laryngoscopy during tracheal intubation to the VideoMiller device (the standard pediatric blade with a camera…
- Trial name
- NCT01371032
- Testing
- VideoMiller, Direct Laryngoscopy
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Cedars-Sinai Medical Center
Eosinophilic Esophagitis
Comparing Anesthetic Techniques in Children Having Esophagogastroduodenoscopies
The purpose of this research study is to compare the safety and effectiveness of three commonly used techniques for delivering anesthesia during a procedure known as esophagogastroduodenoscopy.
- Trial name
- NCT02038894
- Testing
- Intubated with Sevoflurane (IS), Intubated with Propofol (IP), Zofran - no intubation
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cholecystitis, Stomach Cancer
Effect of Modified Stylet Angulation on the Intubation With GlideScope®
The GlideScope® videolaryngoscope usually visualize glottis better than the conventional laryngoscope. Under the visualization of glottis by GlideScope®, the insertion of endotracheal tube, however, is challenging.
- Trial name
- GlideMStylet (NCT02547064)
- Testing
- Glidescope guided intubation, GlideScope®
- Volunteers
- 162 people
- Sponsor
- Keimyung University Dongsan Medical Center
Sedation
Clinical Study to Investigate the Efficacy and the Safety of DA-9501 in Sedation During the Surgery With Epidural Anesthesia or Spinal Anesthesia Without Intubation
The purpose of this study is to examine the efficacy and safety of DA-9501 (Dexmedetomidine) in patients who require sedation during the surgery that requires epidural or spinal anesthesia without intubation under monitored…
- Trial name
- NCT01438957
- Testing
- Dexmedetomidine hydrochloride
- Where
- 12 sites in Japan
- Volunteers
- 119 people
- Sponsor
- Pfizer
Intubation; Difficult
"Neutral Head Position" and "Head-lift Position" for Orotracheal Intubation With "Trachway" Intubating Stylet in Adults
The purpose of this study is to investigate two different patient's head and neck positions(neutral head position and head-lift position) for the effectiveness of orotracheal intubation with using the "Clarus Video System…
- Trial name
- NCT02578992
- Testing
- Head-lift position, 7cm high pillow
- Where
- Taiwan
- Volunteers
- 130 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Tracheal Intubation
Randomised Controlled Trial of Intubation With the McGrath Series 5 Video Laryngoscope vs the Macintosh Laryngoscope
The simplicity of use and intuitive function of the McGrath video-laryngoscope suggests it may have a bigger role than as a back-up to conventional direct laryngoscopy and could possibly be the first-line laryngoscope for…
- Trial name
- NCT00633867
- Testing
- McGrath, Tracheal intubation using Macintosh Laryngoscope
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- NHS Grampian
Hypercapnia, Respiratory Insufficiency
Extracorporeal Lung Assist to Avoid Intubation in Patients Failing Noninvasive Ventilation for Hypercapnic ARF
The study´s intention is to evaluate the feasibility, safety and effectiveness of a pump driven extracorporeal device for removal of carbon dioxide from the blood in oder to avoid intubation and invasive mechanical ventilation in…
- Trial name
- ECLAIR (NCT01784367)
- Testing
- vv-ECCO2R (Novalung GmbH, Germany)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Airway Morbidity
Endotracheal Tube Versus Laryngeal Mask Airway for Esophagogastroduodenoscopy
Esophagogastroduodenoscopy (EGD) is a relatively common procedure in pediatric patients undergoing evaluation for various gastrointestinal ailments.
- Trial name
- NCT01936662
- Testing
- LMA, ETT
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Indiana University
Airway Management, Intubation, Intratracheal
Soiled Airway Tracheal Intubation and the Effectiveness of Decontamination by Paramedics
In more than one-in-five cases of out-of-hospital cardiac arrest, airways are blocked by vomit and blood. Sometimes, paramedics cannot clear the airway using methods they have been taught.
- Conditions
- Airway Management, Intubation, Intratracheal, Laryngoscopy, Vomiting
- Trial name
- SATIATED (NCT03599687)
- Testing
- Training in SALAD technique
- Where
- United Kingdom
- Volunteers
- 164 people
- Sponsor
- Yorkshire Ambulance Service NHS Trust
Premedication, Endotracheal Intubation
Premedication Trial for Tracheal Intubation of the NEOnate
Multicenter double blind randomized controlled trial comparing "atropine+propofol" vs "atropine+atracurium+sufentanil" as a premedication prior to endotracheal intubation of the neonate.
- Trial name
- PRETTINEO (NCT01490580)
- Testing
- atropine+ propofol, atropine + atracurium + sufentanil
- Where
- 6 sites in France
- Volunteers
- 173 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Failed or Difficult Intubation
Three-dimensional Craniofacial Phenotyping of Patients With Difficult Airway
The purpose of this study is to identify differences in craniofacial morphology and tongue size between patients who have a history of difficult airway management and a control group of patients who had an uneventful airway…
- Trial name
- NCT01630694
- Testing
- 3D Laser Scanning of the Head, Measurements and Digital Photo's of the head, neck and Mouth, Ultrasound Exam of the Tongue
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Rochester