Clinical trials: Intubation Complication
Sore-throat, Dysphonia
No Post Intubation Laryngeal Symptoms
The purpose of the study is to test a novel endotracheal tube support device that reduces pressure of the tube on the voice box for prevention of post intubation laryngeal symptoms including sore throat, change in voice and…
- Conditions
- Sore-throat, Dysphonia, Dysphagia, Intubation Complication
- Trial name
- No-PILS (NCT05383417)
- Testing
- EndoClip
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Anesthesia Intubation Complication
Tracheal Palpation of Sliding Cuff to Assess Endotracheal Tube Location
Correct endotracheal tube (ETT) placement is important. Proper ETT position is achieved when the distal tip is in mid-trachea with the head in neutral alignment.
- Trial name
- NCT02502461
- Testing
- cuff palpation
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Saskatchewan
Intubation Complication
Suction Catheter as a Guide for Nasotracheal Intubation Under General Anesthesia
The goal of this clinical trial to study the efficacy of suction catheter guided technique and conventional technique during nasotracheal intubation.
- Trial name
- NCT05717907
- Testing
- suction catheter
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Mahidol University
Infant, Newborn, Diseases, Other Preterm Infants
Surfactant Positive Airway Pressure and Pulse Oximetry Trial
This study compared the use of continuous positive airway pressure initiated at birth with the early administration of surfactant administered through a tube in the windpipe within 1 hour of birth for premature infants born at 24…
- Conditions
- Infant, Newborn, Diseases, Other Preterm Infants, Infant, Small for Gestational Age, Premature Birth
- Trial name
- SUPPORT (NCT00233324)
- Testing
- Surfactant, Continuous Positive Airway Pressure (CPAP), Supplemental oxygen with target saturation of 85 to 89%
- Where
- 22 sites in United States
- Volunteers
- 1,316 people
- Sponsor
- NICHD Neonatal Research Network
Infections, Hospital, Ventilator-Associated Pneumonia
Strategies To Prevent Pneumonia 2 (SToPP2)
Ventilator-associated pneumonia (VAP) is a serious complication in mechanically ventilated critically ill patients. The intervention tested in this project (swabbing the mouth with chlorhexidine before the endotracheal tube is…
- Conditions
- Infections, Hospital, Ventilator-Associated Pneumonia, Mechanical Ventilation Complication
- Trial name
- SToPP2 (NCT00893763)
- Testing
- Pre-intubation CHX, Control
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- University of South Florida
Respiratory Failure, Intubation
Efficiency of the King Vision Video Laryngoscope
The investigators studied the efficiency of Macintosh laryngoscope and the King Vision video laryngoscope in adult patients scheduled for general anesthesia.
- Trial name
- NCT02482870
- Testing
- Macintosh laryngoscope, King Vision video laryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Airway Control, Anesthesia
Ketamine Versus Etomidate for Rapid Sequence Intubation
The purpose of this study is to compare the effectiveness and safety of ketamine and etomidate during rapid sequence intubation (RSI).
- Conditions
- Airway Control, Anesthesia, Intubation, Complication
- Trial name
- NCT01823328
- Testing
- Ketamine, Etomidate
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Hennepin Healthcare Research Institute
Infant, Newborn, Infant, Small for Gestational Age
Hydrocortisone for BPD
The Hydrocortisone and Extubation study will test the safety and efficacy of a 10 day course of hydrocortisone for infants who are less than 30 weeks estimated gestational age and who are intubated at 14-28 days of life.
- Conditions
- Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight, Infant, Premature
- Trial name
- NCT01353313
- Testing
- Hydrocortisone
- Where
- 20 sites in United States
- Volunteers
- 800 people
- Sponsor
- NICHD Neonatal Research Network
Anesthesia Intubation Complication
Comparison of Flexible Fibreoptic Scope With Pentax AWS Videolaryngoscope for Ease of Intubation During Awake Intubation
The purpose of this study is to identify whether Pentax Airway Scope (AWS) videolaryngoscope would be a more effective device compared to flexible fibreoptic scope (FOS) for awake intubation in a difficult airway.
- Trial name
- NCT02614924
- Testing
- Flexible fibreoptic scope, Pentax AWS videolaryngoscope
- Volunteers
- 40 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Mechanical Ventilation Complication, Acute Respiratory Failure
Protocolized Post-Extubation Respiratory Support Study
Invasive mechanical ventilation is common in the medical intensive care unit, and the period of time following extubation remains high risk as 11 to 15% of patients require reintubation after their first extubation.
- Conditions
- Mechanical Ventilation Complication, Acute Respiratory Failure, Intubation Complication
- Trial name
- PROPER (NCT03288311)
- Testing
- Protocolized post-extubation respiratory support, Usual Care
- Where
- United States
- Volunteers
- 751 people
- Sponsor
- Vanderbilt University Medical Center
Failed or Difficult Intubation, Sequela, Intubation;Difficult
Tracheal Intubation Coaching in NICUs
The purpose of the study is to determine the efficacy of video coaching training for neonatology attending providers on tracheal intubation procedural outcomes in neonatal ICUs.
- Conditions
- Failed or Difficult Intubation, Sequela, Intubation;Difficult, Intubation Complication
- Trial name
- NCT03194503
- Testing
- VL Coaching training using C-MAC video laryngoscope
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 1,512 people
- Sponsor
- Children's Hospital of Philadelphia
Mechanical Ventilation Complication
Clinical Study of the Endotracheal Tube Used in Prone Position Ventilation Condition
In this study, the investigators adopt the special endotracheal tube to those patients at prone posture during the operation,or those with acute respiratory distress syndrome in the intensive care unit(ICU), so that the…
- Trial name
- NCT02449356
- Testing
- prone position endotracheal tube(PPT)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wangyuan Zou
Airway Complication of Anaesthesia
Effectiveness and Safety of the Levitan Scope for Laryngoscopy and Tracheal Intubation With a Simulated Difficult Airway
A laryngoscope is a medical instrument that is used to get a view of the voice box and the space in between the vocal cords. A laryngoscope is used to place a breathing tube into the trachea (windpipe or airway) to protect the…
- Trial name
- NCT01491984
- Testing
- Laryngoscopy order: 1) MAC, 2) Levitan, Laryngoscopy order: 1) Levitan, 2) MAC
- Volunteers
- 105 people
- Sponsor
- IWK Health Centre
Intubation Complication
Evaluating the Hemodynamic Effects of Ketamine Versus Etomidate During Rapid Sequence Intubation
The purpose of this study is to compare the hemodynamic effects of ketamine v etomidate during rapid sequence intubation (RSI) in the pre-hospital and emergency department setting.
- Trial name
- Ket-RSI (NCT03545503)
- Testing
- Etomidate, Ketamine
- Where
- United States
- Volunteers
- 428 people
- Sponsor
- South East Area Health Education Center, Wilmington, NC
Anesthesia Intubation Complication, Tracheal Disease
The Effect of Prophylactic Ketorolac on Sore Throat After Thyroid Surgery
Sore throat is one of most frequent complaints related to general anesthesia with tracheal intubation. Although sore throat is regarded as a minor and short-lasting discomfort after surgery, its incidence and intensity in high…
- Trial name
- NCT02039427
- Testing
- Ketorolac, Dexamethasone
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Yeungnam University College of Medicine
Anesthesia Intubation Complication
Propofol for Pediatric Tracheal Intubation With Deep Anesthesia During Sevoflurane Induction
The purpose of this study is to determine the amount of propofol required to achieve 50% of patients obtaining a perfect ("excellent") intubation score of 5 on the Steyn modification of the Helbo-Hansen Intubation Score, when…
- Trial name
- NCT01150838
- Testing
- propofol
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Virginia
Intubation Complication, Intubation;Difficult
Novel Airway Device to Aid Endotracheal Intubations
Pneumaglide is a device designed to facilitate intubation. Patients who are undergoing a surgical procedure under general anesthesia and will require placement of endotracheal tube will be screened and upon fulfilling the…
- Trial name
- NCT03340207
- Testing
- Pneumaglide
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University at Buffalo
Acute Respiratory Failure, Intubation Complication
Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation
Endotracheal intubation is common in the care of critically ill patients. Complications of airway management in this setting are frequently encountered and may be associated with an increased risk of death.
- Trial name
- PrePARE (NCT03026777)
- Testing
- intravenous crystalloid fluid, 500 mL
- Where
- 7 sites in United States
- Volunteers
- 337 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Secretion Removal Above ETT Cuff
Evaluation of Above the Cuff Suctioning During General Anesthesia
The aim of this prospective, randomized, pilot study is compare ease of tracheal intubation, amount of microaspiration and efficacy of secretion removal using three FDA (Food and Drug Administration)-cleared endotracheal tubes…
- Trial name
- NCT01386879
- Testing
- methylene blue
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Thomas Jefferson University
Postoperative Pain
Optimal Sevoflurane Concentration for Intubation in Combination of Clincal Remifentanil Doses
Intubation is a procedure that requires well relaxed muscles while general anesthesia is performed. In order to get adequate muscle relaxation, remifentanil, sevoflurane or both agents in combination have been reported as they…
- Trial name
- NCT02440204
- Testing
- Intubation, Remifentanil, Sevoflurane
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Severance Hospital