Clinical trials: Intubation Complication, active
Intubation Complications
Ramped Versus Supine Position for Emergent Endotracheal Intubation in Adult Patients; Prospective, Randomized, Comparative Study
Endotracheal intubation is a life saving procedure for critically unwell and injured patients presenting to the emergency department.
- Trial name
- NCT06924411
- Testing
- Direct Intubation
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Airway Complication of Anesthesia, Adverse Events
Prospective Assessment Project of AirwaY Management-related Incidents in Adult Anaesthesia Care PAPAYA III
The overall objective of the study is to evaluate and analyze major and minor incidents during airway management in adults under anaesthesia care at all study sites.
- Trial name
- PAPAYA-III (NCT06117176)
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 40,000 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Intubation Complication
Smart Checklist Implementation for Pediatric Tracheal Intubations in the ICU- Multicenter Study
The purpose of the study is to implement a patient-provider dyad tailored, Electronic Health Record (EHR)-informed, digitized Smart Checklist as a Quality Improvement (QI) intervention to support bedside clinician teams to reduce…
- Trial name
- SMART PICU (NCT06085326)
- Testing
- Smart Checklist
- Where
- 6 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Children's Hospital of Philadelphia
Postoperative Pulmonary Complications
Postoperative Pulmonary Complications After Use of Supraglottic Airway Devices and Neuromuscular Blockade
SupAIR is an international, multicenter, randomized controlled trial investigating whether airway management and neuromuscular blockade during general anesthesia influence postoperative pulmonary complications.
- Trial name
- SupAIR (NCT07829094)
- Testing
- Airway management strategy, Initiation of neuromuscular blockade (NMB), Deep versus moderate neuromuscular blockade (NMB)
- Volunteers
- 6,800 people
- Sponsor
- University Hospital Ulm
Anesthesia, Airway Complication of Anesthesia
Apnoeic Oxygenation During Pediatric Tracheal Intubation
The goal of this randomized, controlled, single-blinded clinical trial is to evaluate the effectiveness of apnoeic Oxygenation in pediatric anesthesia.
- Conditions
- Anesthesia, Airway Complication of Anesthesia, Anesthesia; Adverse Effect
- Trial name
- NCT06576596
- Testing
- apnoeic Oxygenation
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Heidelberg
Intubation, Nasogastric, Intubation Intraesophageal
Comparing Two Methods to Measure Nasogastric Tube Length
The goal of this clinical trial is to learn if using a novel nasogastric tube assisted placement system (NCKU-NG system) can more accurately place the nasogastric tube at the optimal position in the stomach compared to…
- Conditions
- Intubation, Nasogastric, Intubation Intraesophageal, Intubation Depth, Intubation Times
- Trial name
- NCT06982495
- Testing
- NCKU-NG system, Conventional blind insertion
- Volunteers
- 220 people
- Sponsor
- National Cheng-Kung University Hospital
Neurogenic Dysphagia, Traumatic Brain Injury
Register Study: Implementation of Pharyngeal Electrostimulation Therapy for the Treatment of Acute Neurogenic Dysphagia
Neurogenic dysphagia occurs with disruption of neurological systems or processes involved in the execution of coordinated and safe swallowing.
- Conditions
- Neurogenic Dysphagia, Traumatic Brain Injury, Stroke, Dysphagia
- Trial name
- R:IphEst (NCT05190718)
- Testing
- Pharyngeal electrostimulation
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Karl Landsteiner University of Health Sciences
Anesthesia, Intubation; Difficult or Failed
PrediSuisse: Automatized Assessment of Difficult Airway
In the "PrediSuisse" research project, the investigators aim to create a reliable, reproducible, ultra-portable and radiation-free automatized software, able to identify automatically collected features, facial characteristics…
- Conditions
- Anesthesia, Intubation; Difficult or Failed, Airway Complication of Anesthesia
- Trial name
- PrediSuisse (NCT06453525)
- Testing
- intubation
- Where
- Switzerland
- Volunteers
- 1,800 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Respiratory Distress Syndrome (& [Hyaline Membrane Disease]), Respiratory Distress Syndrome (Neonatal)
Surfactant Administration Methods in Preterm Infants With RDS: A Swedish Cohort Study
The goal of this observational study is to evaluate different methods of surfactant administration in preterm infants with respiratory distress syndrome (RDS).
- Conditions
- Respiratory Distress Syndrome (& [Hyaline Membrane Disease]), Respiratory Distress Syndrome (Neonatal), Respiratory Distress Syndrome (RDS), Respiratory Distress Syndrome of Newborn
- Trial name
- NCT07550218
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Vastra Gotaland Region
Intubation Complication
Comparison of First Attempt Success Based on Endotracheal Tube Type During Videolaryngoscope-guided Intubation Without Stylet
Patients are randomly assigned to either the oral RAE tube group (Group O) or the reinforced tube group (Group R). In both groups, tracheal intubation is performed using a videolaryngoscope without a stylet, and the first-attempt…
- Trial name
- NCT07682480
- Testing
- endotracheal tube
- Volunteers
- 246 people
- Sponsor
- Seoul National University Hospital
Anesthesia Intubation Complication
Ability to Maintain Saturation Levels Without Oxygen Supplementation as a Extubation Criteria Without TOF Monitoring Equipment
Patients undergoing general anesthesia will have an endotracheal tube inserted. Adequate muscle strength recovery in the recovery room is crucial to ensure before extubation.
- Trial name
- NCT06275542
- Testing
- Train of four monitoring device intraoperative, Neostigmine, Air chalenge prior to extubation
- Where
- Indonesia
- Volunteers
- 240 people
- Sponsor
- University of Surabaya
Cleft Palate, Cleft Lip
Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring
Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population.
- Conditions
- Cleft Palate, Cleft Lip, Laryngospasm, Bronchospasm
- Trial name
- NCT07651904
- Testing
- Standard General Anesthesia per Institutional Protocol
- Volunteers
- 150 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Intubation; Difficult or Failed, Intubation Complication
Non-inferiority Trial Comparing visionPRO to Glidescope Video Laryngoscopes
Indirect video laryngoscope tracheal intubation with the GlideScope (Verathon Inc., Bothell, USA) has become a well-established technique in emergency and clinical anaesthesia, offering first-pass intubation success rates…
- Conditions
- Intubation; Difficult or Failed, Intubation Complication, Video Laryngoscopy, Airway Management
- Trial name
- NCT06676462
- Testing
- Video laryngoscopy with visionPRO, Video laryngoscopy with Glidescope
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pressor Response
Dexmedetomidine Nebulization for Attenuation of Pressor Response to Laryngoscopy and Endotracheal Intubation in Sever Preeclamptic Patients
Dexmedetomidine nebulization in sever preeclamptic patients
- Trial name
- NCT07164326
- Testing
- Dexmedetomidine, Saline
- Volunteers
- 100 people
- Sponsor
- Assiut University
Critical Illness, Difficult; Intubation, Postpartum, During Puerperium
Ultrasound Airway Assessment of Critically Ill Preeclamptic; Comparison Between Two Technique
Unexpected difficult airway exposes the patient to serious morbidity and even mortality. The changes in pregnancy and preeclampsia increase the risk of difficult intubation.
- Conditions
- Critical Illness, Difficult; Intubation, Postpartum, During Puerperium, Pre-Eclampsia
- Trial name
- NCT06651879
- Testing
- techniques of ultrasound examination of the airway
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Post Operative Sore Throat, Hoarseness
Efficacy of Flurbiprofen Spray for Postoperative Sore Throat Following Double-Lumen Endobronchial Intubation
The goal of this study is to evaluate whether topical flurbiprofen reduces the incidence and severity of postoperative sore throat (POST) and hoarseness in patients undergoing double-lumen tube (DLT) intubation for elective…
- Trial name
- FLURBI-POST (NCT07163429)
- Testing
- Flurbiprofen 8.75 MG, Saline spray
- Where
- Thailand
- Volunteers
- 58 people
- Sponsor
- Kittitorn Supphapipat, MD
Delayed Sequence Intubation, Rapid Sequence Induction and Intubation
Comparison of Peri-intubation Oxygenation Values and Complications in Patients Intubated With the Delayed Versus Rapid Sequence Intubation Protocols
This study compares two different methods of helping patients breathe by placing a tube in their airway (intubation) in an emergency setting.
- Conditions
- Delayed Sequence Intubation, Rapid Sequence Induction and Intubation, Intubation, Intubation Complications
- Trial name
- DSI vs RSI (NCT07380763)
- Testing
- Delayed Sequence Intubation, Rapid Sequence Intubation
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Intubation, Intubation Complications
A Stepped Wedge Cluster Randomised Trial Of Video Versus Direct Laryngoscopy For Intubation Of Newborn Infants
Many newborn babies have difficulty breathing. When babies need a lot of help, a doctor will intubate them - i.e. put a tube into their windpipe (trachea) - so that they can be given support with a breathing machine.
- Conditions
- Intubation, Intubation Complications, Infant, Newborn, Infant Respiratory Distress Syndrome
- Trial name
- NEU-VODE (NCT06757543)
- Testing
- Video laryngoscopy, Direct laryngoscopy with standard laryngoscope
- Where
- 17 sites in Croatia, Czechia and 8 more
- Volunteers
- 840 people
- Sponsor
- University College Dublin
Intubation Complication
Incidence of Acute Laryngeal Injury Following Endotracheal Intubation
The purpose of this investigation is to delineate the incidence of acute and chronic laryngeal injury following intubation within our health system.
- Trial name
- NCT03250975
- Testing
- Budesonide and Azithromycin
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Vanderbilt University Medical Center
Emergence Delirium, Anesthesia
Emergence Delirium、fBFI-ENO Score (Extraversion + Neuroticism - Openness) Based on the Fast Big Five Personality Scale-10、An Adult Patient With ASAI-III Who is Scheduled for Elective Non-cardiac Surgery and is to Undergo General Anesthesia With Tracheal Intubation
The aim of this study is to verify the generalizability of the fBFI-ENO score (extraversion + neuroticism - openness) constructed based on the Rapid Big Five Personality Scale - 10 across different genders, ages, and surgical…
- Trial name
- NCT07775768
- Volunteers
- 880 people
- Sponsor
- Hongjiao Xu